SEMA6D (NM_153616) Human Untagged Clone

CAT#: SC124441

SEMA6D (untagged)-Human sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEMA6D
• Synonyms: FLJ11598; KIAA1479
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_153616, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGGTCTTCCTGCTTTGTGCCTACATACTGCTGCTGATGGTTTCCCAGTTGAGGGCAGTCAGCTTTC
  CTGAAGATGATGAACCCCTTAATACTGTCGACTATCACTATTCAAGGCAATATCCGGTTTTTAGAGGACG
  CCCTTCAGGCAATGAATCGCAGCACAGGCTGGACTTTCAGCTGATGTTGAAAATTCGAGACACACTTTAT
  ATTGCTGGCAGGGATCAAGTTTATACAGTAAACTTAAATGAAATGCCCAAAACAGAAGTAATACCCAACA
  AGAAACTGACATGGCGATCAAGACAACAGGATCGAGAAAACTGTGCTATGAAAGGCAAGCATAAAGATGA
  ATGCCACAACTTTATCAAAGTATTTGTTCCAAGAAACGATGAGATGGTTTTTGTTTGTGGTACCAATGCA
  TTCAATCCCATGTGTAGATACTACAGGTTGAGTACCTTAGAATATGATGGGGAAGAAATTAGTGGCCTGG
  CAAGATGCCCATTTGATGCCAGACAAACCAATGTTGCCCTCTTTGCTGATGGGAAGCTGTATTCTGCCAC
  AGTGGCTGACTTCTTGGCCAGCGATGCCGTTATTTATCGAAGCATGGGTGATGGATCTGCCCTTCGCACA
  ATAAAATATGATTCCAAATGGATAAAAGAGCCACACTTTCTTCATGCCATAGAATATGGAAACTATGTCT
  ATTTCTTCTTTCGAGAAATCGCTGTCGAACATAATAATTTAGGCAAGGCTGTGTATTCCCGCGTGGCCCG
  CATATGTAAAAACGACATGGGTGGTTCCCAGCGGGTCCTGGAGAAACACTGGACTTCATTTCTAAAGGCT
  CGGCTGAACTGTTCTGTCCCTGGAGATTCGTTTTTCTACTTTGATGTTCTGCAGTCTATTACAGACATAA
  TACAAATCAATGGCATCCCCACTGTGGTCGGGGTGTTTACCACGCAGCTCAATAGCATCCCTGGTTCTGC
  TGTCTGTGCATTTAGCATGGATGACATTGAAAAAGTATTCAAAGGACGGTTTAAGGAACAGAAAACTCCA
  GATTCTGTTTGGACAGCAGTTCCCGAAGACAAAGTGCCAAAGCCAAGGCCTGGCTGTTGTGCAAAACACG
  GCCTTGCCGAAGCTTATAAAACCTCCATCGATTTCCCGGATGAAACTCTGTCATTCATCAAATCTCATCC
  CCTGATGGACTCTGCCGTTCCACCCATTGCCGATGAGCCCTGGTTCACAAAGACTCGGGTCAGGTACAGA
  CTGACGGCCATCTCAGTGGACCATTCAGCCGGACCCTACCAGAACTACACAGTCATCTTTGTTGGCTCTG
  AAGCTGGCATGGTACTTAAAGTTCTGGCAAAGACCAGTCCTTTCTCTTTGAACGACAGCGTATTACTGGA
  AGAGATTGAAGCCTACAACCATGCAAAGTGCAGTGCTGAGAATGAGGAAGACAAAAAGGTCATCTCATTA
  CAGTTGGATAAAGATCACCACGCTTTATATGTGGCGTTCTCTAGCTGCATTATCCGCATCCCCCTCAGTC
  GCTGTGAGCGTTATGGATCATGTAAAAAGTCTTGTATTGCATCTCGTGACCCGTATTGTGGCTGGTTAAG
  CCAGGGATCCTGTGGTAGAGTGACCCCAGGGATGCTTGCTGAAGGATATGAACAAGACACAGAATTCGGC
  AACACAGCTCATCTAGGGGACTGCCATGGTGTACGATGGGAAGTCCAGTCTGGAGAGTCCAACCAGATGG
  TCCACATGAATGTCCTCATCACCTGTGTCTTTGCTGCTTTTGTTTTGGGGGCATTCATTGCAGGTGTGGC
  AGTATACTGCTATCGAGACATGTTTGTTCGGAAAAACAGAAAGATCCATAAAGATGCAGAGTCCGCCCAG
  TCATGCACAGACTCCAGTGGAAGTTTTGCCAAACTGAATGGTCTCTTTGACAGCCCTGTCAAGGAATACC
  AACAGAATATTGATTCTCCTAAACTGTATAGTAACCTGCTAACCAGTCGGAAAGAGCTACCACCCAATGG
  AGATACTAAATCCATGGTAATGGACCATCGAGGGCAACCTCCAGAGTTGGCTGCTCTTCCTACTCCTGAG
  TCTACACCCGTGCTTCACCAGAAGACCCTGCAGGCCATGAAGAGCCACTCAGAAAAGGCCCATGGCCATG
  GAGCTTCAAGGAAAGAAACCCCTCAGTTTTTTCCGTCTAGTCCGCCACCTCATTCCCCATTAAGTCATGG
  GCATATCCCCAGTGCCATTGTTCTTCCAAATGCTACCCATGACTACAACACGTCTTTCTCAAACTCCAAT
  GCTCACAAAGCTGAAAAGAAGCTTCAAAACATTGATCACCCTCTCACAAAGTCATCCAGTAAGAGAGATC
  ACCGGCGTTCTGTTGATTCCAGAAATACCCTCAATGATCTCCTGAAGCATCTGAATGACCCAAATAGTAA
  CCCCAAAGCCATCATGGGAGACATCCAGATGGCACACCAGAACTTAATGCTGGATCCCATGGGATCGATG
  TCTGAGGTCCCACCTAAAGTCCCTAACCGGGAGGCATCGCTATACTCCCCTCCTTCAACTCTCCCCAGAA
  ATAGCCCAACCAAGCGAGTGGATGTCCCCACCACTCCTGGAGTCCCAATGACTTCTCTGGAAAGACAAAG
  AGGTTATCACAAAAATTCCTCCCAGAGGCACTCTATATCTGCTATGCCTAAAAACTTAAACTCACCAAAT
  GGTGTTTTGTTATCCAGACAGCCTAGTATGAACCGTGGAGGATATATGCCCACCCCCACTGGGGCGAAGG
  TGGACTATATTCAGGGAACACCAGTGAGTGTTCATCTGCAGCCTTCCCTCTCCAGACAGAGCAGCTACAC
  CAGTAATGGCACTCTTCCTAGGACGGGACTAAAGAGGACGCCGTCCTTAAAACCTGACGTGCCACCAAAG
  CCTTCCTTTGTTCCTCAAACCCCATCTGTCAGACCACTGAACAAATACACATACTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_153616 unedited
  TAGGCGGCCCGCGAATTCGCACGAGGCCTCGTGCCGAATTCGGCACGAGGGGGATATCTA
  TTTTTACAATATTTTTCTTTATTTTCTTTCTTCCTTGCGCGTGGCAAGCTTTTTTTTTTC
  TTTTTCTTTTTTCTTACCAGCCTCCCCCCAATGAGGTAGCTCAGTGGCATTTCTGAGCAG
  GGGCCACCCTGACTTCACCTTGGCCCACCATGAGGGTCTTCCTGCTTTGTGCCTACATAC
  TGCTGCTGATGGTTTCCCAGTTGAGGGCAGTCAGCTTTCCTGAAGATGATGAACCCCTTA
  ATACTGTCGACTATCACTATTCAAGGCAATATCCGGTTTTTAGAGGACGCCCTTCAGGCA
  ATGAATCGCAGCACAGGCTGGACTTTCAGCTGATGTTGAAAATTCGAGACACACTTTATA
  TTGCTGGCAGGGATCAAGTTTATACAGTAAACTTAAATGAAATGCCCAAAACAGAAGTAA
  TACCAAACAAGAAACTGACATGGCGATCAAGACTACAGGATCGAGAAAACTGTGCTATGA
  AAGGCAAGCATAAAGATGAATGCCACAACTTTATCAAAGTATTTGTTCCAAGAAACGATG
  AGATGGTTTTTGTTTGTGGTACCAATGCATTCAATCCCATGTGTAGATACTACAGGTTGA
  GTACCTTAGAATATGATGGGGAAAGAAATAGTGGCCTGGCAAGATGCCCATTTGATGCCC
  AGACAACCAATGTTGCCCTCTTTGCTGATGGGAGCTGTATTCTGCCCAGTGGCTGACTTC
  TTGCCAGCGATGCCGNTATTATCGAGCATGGTGATGGATCTGCCCTTCGCACATAAATAT
  GATTCCAATGGATAAAAGAGCACACTTCTTCTGCATAGATATGAAACTTGTCTATTCTCT
  TTCGAAACGCGTCGACATATAACATGCAGCTGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_153616 unedited
  TGAACATCGGTGATGGCAACTTCCAGGNCCAGNATAGCACTGGGGNAGGGGTCACAGGNA
  TGCCACCCGGGTATCTGTTCAGAAAAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCAGGTAAACTCACATGTGGTATTTACAGTA
  TATTGTCATTACCTGCATGACTTAGGAAAAAATTCTCACATAACACAACACAGACAACAT
  GATTGCCCCACTGTTAGGTTTTTACAGACTGTTTCTGTTAACCCAATTACAATTCCTTTC
  ATATGTCTTTCTTTTGTCTTCTATTTTTGTTTGTTTGTTTGTTTTTTGTTTCTTACCTTG
  GGGGGTAGGAGGAGTTAAAGGAGGAAAAATTTTACTATTGGGGGGGGGGNGGAAACCAAC
  ACAATCAAAATAAAACCTTATTANTGTGTCCAAGGTTAAATANAGTGACTCAGGCTTTGA
  TTCACAGTGGACAGGAAAATTTTACTACTGAATACTGGAAAATAAATCAGGGATACCTCT
  TAATATCTTGATCTCCTTAACCTGGCCNGACTGGAATACAAGTTTTAATGAATAGCACCC
  CAAAATCCCTTGCAACTCTTACATTCTGGCCTTGGGGCCCAAATAAGTAAAGTTCATCAT
  TTTGATGGTCAAAGGACCCCCGATTCTATTCCCCTTTCAAAGCTGAACCCCATGGACTCC
  GGGGGAAAATAGAATTGCCCCCCGTTCCGCCCTGCTTAATGGAAACAACTCCCCTCCCCA
  AAAAAAACCAATGGGCACCTTAACCAACCCAAGGGGTACCAAACAAACCCCCCCCCTCTC
  CCACCGCCAATCCCCCCCGGCCGACCAAATCAAAAAAAAAAATTTATGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_153616
• ORF Size: 2997 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_153616.1, NP_705869.1
• RefSeq Size: 5884
• RefSeq ORF: 2997
• Locus ID: 80031
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance
• Gene Summary: Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]
  Transcript Variant: This variant (2) lacks two internal exons compared to variant 4. The encoded isoform (2) is missing an internal segment relative to isoform 4.