ApoER2 (LRP8) (NM_033300) Human Untagged Clone

CAT#: SC124693

LRP8 (untagged)-Human low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LRP8
• Synonyms: APOER2; HSZ75190; LRP-8; MCI1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_033300, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGCCTCCCCGAGCCGGGCCCTCTCCGGCTTCTGGCGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGC
  TGCAGCTCCAGCATCTTGCGGCGGCAGCGGCTGATCCGCTGCTCGGCGGCCAAGGGCCGGCCAAGGATTG
  CGAAAAGGACCAATTCCAGTGCCGGAACGAGCGCTGCATCCCCTCTGTGTGGAGATGCGACGAGGACGAT
  GACTGCTTAGACCACAGCGACGAGGACGACTGCCCCAAGAAGACCTGTGCAGACAGTGACTTCACCTGTG
  ACAACGGCCACTGCATCCACGAACGGTGGAAGTGTGACGGCGAGGAGGAGTGTCCTGATGGCTCCGATGA
  GTCCGAGGCCACTTGCACCAAGCAGGTGTGTCCTGCAGAGAAGCTGAGCTGTGGACCCACCAGCCACAAG
  TGTGTACCTGCCTCGTGGCGCTGCGACGGGGAGAAGGACTGCGAGGGTGGAGCGGATGAGGCCGGCTGTG
  CTACCTGGCTGAACGAGTGTCTGCACAACAATGGCGGCTGCTCACACATCTGCACTGACCTCAAGATTGG
  CTTTGAATGCACGTGCCCAGCAGGCTTCCAGCTCCTGGACCAGAAGACCTGTGGCGACATTGATGAGTGC
  AAGGACCCAGATGCCTGCAGCCAGATCTGTGTCAATTACAAGGGCTATTTTAAGTGTGAGTGCTACCCTG
  GCTACGAGATGGACCTACTGACCAAGAACTGCAAGGCTGCTGCTGGCAAGAGCCCATCCCTAATCTTCAC
  CAACCGGCACGAGGTGCGGAGGATCGACCTGGTGAAGCGGAACTATTCACGCCTCATCCCCATGCTCAAG
  AATGTCGTGGCACTAGATGTGGAAGTTGCCACCAATCGCATCTACTGGTGTGACCTCTCCTACCGTAAGA
  TCTATAGCGCCTACATGGACAAGGCCAGTGACCCGAAAGAGCAGGAGGTCCTCATTGACGAGCAGTTGCA
  CTCTCCAGAGGGCCTGGCAGTGGACTGGGTCCACAAGCACATCTACTGGACTGACTCGGGCAATAAGACC
  ATCTCAGTGGCCACAGTTGATGGTGGCCGCCGACGCACTCTCTTCAGCCGTAACCTCAGTGAACCCCGGG
  CCATCGCTGTTGACCCCCTGCGAGGGTTCATGTATTGGTCTGACTGGGGGGACCAGGCCAAGATTGAGAA
  ATCTGGGCTCAACGGTGTGGACCGGCAAACACTGGTGTCAGACAATATTGAATGGCCCAACGGAATCACC
  CTGGATCTGCTGAGCCAGCGCTTGTACTGGGTAGACTCCAAGCTACACCAACTGTCCAGCATTGACTTCA
  GTGGAGGCAACAGAAAGACGCTGATCTCCTCCACTGACTTCCTGAGCCACCCTTTTGGGATAGCTGTGTT
  TGAGGACAAGGTGTTCTGGACAGACCTGGAGAACGAGGCCATTTTCAGTGCAAATCGGCTCAATGGCCTG
  GAAATCTCCATCCTGGCTGAGAACCTCAACAACCCACATGACATTGTCATCTTCCATGAGCTGAAGCAGC
  CAAGAGCTCCAGATGCCTGTGAGCTGAGTGTCCAGCCTAATGGAGGCTGTGAATACCTGTGCCTTCCTGC
  TCCTCAGATCTCCAGCCACTCTCCCAAGTACACATGTGCCTGTCCTGACACAATGTGGCTGGGTCCAGAC
  ATGAAGAGGTGCTACCGAGCACCTCAATCTACCTCAACTACGACGTTAGCTTCTACCATGACGAGGACAG
  TACCTGCCACCACAAGAGCCCCCGGGACCACCGTCCACAGATCCACCTACCAGAACCACAGCACAGAGAC
  ACCAAGCCTGACAGCTGCAGTCCCAAGCTCAGTTAGTGTCCCCAGGGCTCCCAGCATCAGCCCGTCTACC
  CTAAGCCCTGCAACCAGCAACCACTCCCAGCACTATGCAAATGAAGACAGTAAGATGGGCTCAACAGTCA
  CTGCCGCTGTTATCGGGATCATCGTGCCCATAGTGGTGATAGCCCTCCTGTGCATGAGTGGATACCTGAT
  CTGGAGAAACTGGAAGCGGAAGAACACCAAAAGCATGAATTTTGACAACCCAGTCTACAGGAAAACAACA
  GAAGAAGAAGACGAAGATGAGCTCCATATAGGGAGAACTGCTCAGATTGGCCATGTCTATCCTGCAGCAA
  TCAGCAGCTTTGATCGCCCACTGTGGGCAGAGCCCTGTCTTGGGGAGACCAGAGAACCGGAAGACCCAGC
  CCCTGCCCTCAAGGAGCTTTTTGTCTTGCCGGGGGAACCAAGGTCACAGCTGCACCAACTCCCGAAGAAC
  CCTCTTTCCGAGCTGCCTGTCGTCAAATCCAAGCGAGTGGCATTAAGCCTTGAAGATGATGGACTACCCT
  GA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_033300 unedited
  GCCGCGAAATCGGCACGAGGGCAACCCCGGCGCCGCGGCAAGGACTCGGAGGGCTGAGAC
  GCGGCGGCGGCGGCGCGGGGAGCGCGGGGCGCGGCGGCCGGAGCCCCGGGCCCGCCATGG
  GCCTCCCCGAGCCGGGCCCTCTCCGGCTTCTGGCGCTGCTGCTGCTGCTGCTGCTGCTGC
  TGCTGCTGCGGCTCCAGCATCTTGCGGCGGCAGCGGCTGATCCGCTGCTCGGCGGCCAAG
  GGCCGGCCAAGGAGTGCGAAAAGGACCAATTCCAGTGCCGGAACGAGCGCTGCATCCCCT
  CTGTGTGGAGATGCGACGAGGACGATGACTGCTTAGACCACAGCGACGAGGACGACTGCC
  CCAAGAAGACCTGTGCAGACAGTGACTTCACCTGTGACAACGGCCACTGCATCCACGAAC
  GGTGGAAGTGTGACGGCGAGGAGGAGTGTCCTGATGGCTCCGATGAGTCCGAGGCCACTT
  GCACCAAGCANGGTGTGTCCTGCAGAGAAGCTGAGCTGTGGACCCACCAGCCACAAGTGT
  GTACCTGCCTCGTGGCGCTGCGACGGGGAGAAGGACTGCGAGGGTGGAGCGGATGAGGCC
  GGCTGTGCTACCTCACTGGGCACCTGCCGTGGGGACGAGTTCCAGTGTGGGGATGGGACA
  TGTGTCCTTGCATCGAGCACTGCACCAGGAGCANGACTGTCCAGAGGGAGTGATGAAGCT
  GGCTGCTACAGGGCTGAACGGTGTCTGCACACATGGGCGCTGCTACACATCTGCACTGAC
  TCAAGATGGCTTGAATGCCCTGCCAGCAGCTTCCACTCCTGACANAAACCTGGGCAAATT
  GATGATGCAGGACCAATCCTGAACCAAACTGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_033300 unedited
  GCTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTACTTATGTT
  GATGGATAGCCACAAAGCATAATCATCTTATTTACAAAAAACAAATGCCCCAAAACCTAA
  AAAAGCCCCCCCAGCAACCAAACATCTTCTGTAAATATAGTTTTTAAATGATGAGTAAGG
  TACTGTGCCATTGGCCCCCATTTGGTTATGTGCATCATGTTAGTCAGCAGTAGCCATTCC
  ACGAATTCCTCATGGGTAGTGCAACCAGTTAAAAAGTGTATAAAACATTATACATAGAAA
  AACTCTCACATCCTTTGGATGTTTGCAGTTCATCATAACTTTGTGGTTACCTTTCCGCAA
  CATAAATTTAAAAAAAAAATCACACACACACATACACTCACACAGACCCATATATAGAAA
  CCCATTCATCCAGTCATACACCATCCAGAGTGTAGTGCATGGGACTGAATTCCATGAGGC
  ACGAAGGGGGTGATCCCATCCTCAGGGTAGTCCATCATCTTCAAGGCTTAATGCCACTCG
  CTTGGATTTGACGACAGGCAGCTCGGAAAGAGGGTTCTTCGGGAGTTGGTGCAGCTGTGA
  CCTTGGTTCCCCCGGCAAGACANAAAGCTCCTTGAGGGCAGGGGCTGGGTCTTCCGGTTC
  TCTGGTCTTCCCAGACAGGGCTCTGCCCCAGTGGGCGATCAAGCTGCTGATTGCTGCAGG
  ATAAACATGCCCATCTGGACCAGTCTCCCTATATGGAGCCCATCTTCATTTTCTTCCTCG
  GGTGGTTTCTGGAGAATGGGGTTGCCAAAATTCAGCTTTTGGGCGTCCTCCCGCTTCCGG
  TTCTCCAAATAAGGTTCCCCTCCCGCCCCGAAGGCTATCCCCTTTGGGCCCCAGAACCCC
  AAAACCGGGGCCGCCTGTGGGCCATCTTACGGTTCCTTCGAAAGGTTGGAAACGTCCTCG
  GTTTCGGTTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_033300
• ORF Size: 2382 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_033300.2, NP_150643.2
• RefSeq Size: 7273
• RefSeq ORF: 2382
• Locus ID: 7804
• Domains: ldl_recept_b, EGF_CA, ldl_recept_a, EGF, EGF
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Gene Summary: This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011]
  Transcript Variant: This variant (2) lacks two consecutive coding exons but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.