PAPP A2 (PAPPA2) (NM_020318) Human Untagged Clone

CAT#: SC125584

PAPPA2 (untagged)-Human pappalysin 2 (PAPPA2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PAPPA2
• Synonyms: PAPP-A2; PAPP-E; PAPPE; PLAC3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC125584 sequence for NM_020318 edited (data generated by NextGen Sequencing)
  ATGATGTGCTTAAAGATCCTAAGAATAAGCCTGGCGATTTTGGCTGGGTGGGCACTCTGT
  TCTGCCAACTCTGAGCTGGGCTGGACACGCAAGAAATCCTTGGTTGAGAGGGAACACCTG
  AATCAGGTGCTGTTGGAAGGAGAACGTTGTTGGCTGGGGGCCAAGGTTCGAAGACCCAGA
  GCTTCTCCACAGCATCACCTCTTTGGAGTCTACCCCAGCAGGGCTGGGAACTACCTAAGG
  CCCTACCCCGTGGGGGAGCAAGAAATCCATCATACAGGACGCAGCAAACCAGACACTGAA
  GGAAATGCTGTGAGCCTTGTTCCCCCAGACCTGACTGAAAATCCAGCAGGACTGAGGGGT
  GCAGTTGAAGAGCCGGCTGCCCCATGGGTAGGGGATAGTCCTATTGGGCAATCTGAGCTG
  CTGGGAGATGATGACGCTTATCTCGGCAATCAAAGATCCAAGGAGTCTCTAGGTGAGGCC
  GGGATTCAGAAAGGCTCAGCCATGGCTGCCACTACTACCACCGCCATTTTCACAACCCTG
  AACGAACCCAAACCAGAGACCCAAAGGAGGGGCTGGGCCAAGTCCAGGCAGCGTCGCCAA
  GTGTGGAAGAGGCGGGCGGAAGATGGGCAGGGAGACTCCGGTATCTCTTCACATTTCCAA
  CCTTGGCCCAAGCATTCCCTTAAACACAGGGTCAAAAAGAGTCCACCGGAGGAAAGCAAC
  CAAAATGGTGGAGAGGGCTCCTACCGAGAAGCAGAGACCTTTAACTCCCAAGTAGGACTG
  CCCATCTTATACTTCTCTGGGAGGCGGGAGCGGCTGCTGCTGCGTCCAGAAGTGCTGGCT
  GAGATTCCCCGGGAGGCGTTCACAGTGGAAGCCTGGGTTAAACCGGAGGGAGGACAGAAC
  AACCCAGCCATCATCGCAGGTGTGTTTGATAACTGCTCCCACACTGTCAGTGACAAAGGC
  TGGGCCCTGGGGATCCGCTCAGGGAAGGACAAGGGAAAGCGGGATGCTCGCTTCTTCTTC
  TCCCTCTGCACCGACCGCGTGAAGAAAGCCACCATCTTGATTAGCCACAGTCGCTACCAA
  CCAGGCACATGGACCCATGTGGCAGCCACTTACGATGGACGGCACATGGCCCTGTATGTG
  GATGGCACTCAGGTGGCTAGCAGTCTAGACCAGTCTGGTCCCCTGAACAGCCCCTTCATG
  GCATCTTGCCGCTCTTTGCTCCTGGGGGGAGACAGCTCTGAGGATGGGCACTATTTCCGT
  GGACACCTGGGCACACTGGTTTTCTGGTCGACCGCCCTGCCACAAAGCCATTTTCAGCAC
  AGTTCTCAGCATTCAAGTGGGGAGGAGGAAGCGACTGACTTGGTCCTGACAGCGAGCTTT
  GAGCCTGTGAACACAGAGTGGGTTCCCTTTAGAGATGAGAAGTACCCACGACTTGAGGTT
  CTCCAGGGCTTTGAGCCAGAGCCTGAGATTCTGTCGCCTTTGCAGCCCCCACTCTGTGGG
  CAAACAGTCTGTGACAATGTGGAATTGATCTCCCAGTACAATGGATACTGGCCCCTTCGG
  GGAGAGAAGGTGATACGCTACCAGGTGGTGAACATCTGTGATGATGAGGGCCTAAACCCC
  ATTGTGAGTGAGGAGCAGATTCGTCTGCAGCACGAGGCACTGAATGAGGCCTTCAGCCGC
  TACAACATCAGCTGGCAGCTGAGCGTCCACCAGGTCCACAATTCCACCCTGCGACACCGG
  GTTGTGCTTGTGAACTGTGAGCCCAGCAAGATTGGCAATGACCATTGTGACCCCGAGTGT
  GAGCACCCACTCACAGGCTATGATGGGGGTGACTGCCGCCTGCAGGGCCGCTGCTACTCC
  TGGAACCGCAGGGATGGGCTCTGTCACGTGGAGTGTAACAACATGCTGAACGACTTTGAC
  GACGGAGACTGCTGCGACCCCCAGGTGGCTGATGTGCGCAAGACCTGCTTTGACCCTGAC
  TCACCCAAGAGGGCATACATGAGTGTGAAGGAGCTGAAGGAGGCCCTGCAGCTGAACAGT
  ACTCACTTCCTCAACATCTACTTTGCCAGCTCAGTGCGGGAAGACCTTGCAGGTGCTGCC
  ACCTGGCCTTGGGACAAGGACGCTGTCACTCACCTGGGTGGCATTGTCCTCAGCCCAGCA
  TATTATGGGATGCCTGGCCACACCGACACCATGATCCATGAAGTGGGACATGTTCTGGGA
  CTCTACCATGTCTTTAAAGGAGTCAGTGAAAGAGAATCCTGCAATGACCCCTGCAAGGAG
  ACAGTGCCATCCATGGAAACGGGAGACCTCTGTGCCGACACCGCCCCCACTCCCAAGAGT
  GAGCTGTGCCGGGAACCAGAGCCCACTAGTGACACCTGTGGCTTCACTCGCTTCCCAGGG
  GCTCCGTTCACCAACTACATGAGCTACACGGATGATAACTGCACTGACAACTTCACTCCT
  AACCAAGTGGCCCGAATGCATTGCTATTTGGACCTAGTCTATCAGCAGTGGACTGAAAGC
  AGAAAGCCCACCCCCATCCCCATTCCACCTATGGTCATCGGACAGACCAACAAGTCCCTC
  ACTATCCACTGGCTGCCTCCTATTAGTGGAGTTGTATATGACAGGGCCTCAGGCAGCTTG
  TGTGGCGCTTGCACTGAAGATGGGACCTTTCGTCAGTATGTGCACACAGCTTCCTCCCGG
  CGGGTGTGTGACTCCTCAGGTTATTGGACCCCAGAGGAGGCTGTGGGGCCTCCTGATGTG
  GATCAGCCCTGCGAGCCAAGCTTACAGGCCTGGAGCCCTGAGGTCCACCTGTACCACATG
  AACATGACGGTCCCCTGCCCCACAGAAGGCTGTAGCTTGGAGCTGCTCTTCCAACACCCG
  GTCCAAGCCGACACCCTCACCCTGTGGGTCACTTCCTTCTTCATGGAGTCCTCGCAGGTC
  CTCTTTGACACAGAGATCTTGCTGGAAAACAAGGAGTCAGTGCACCTGGGCCCCTTAGAC
  ACTTTCTGTGACATCCCACTCACCATCAAACTGCACGTGGATGGGAAGGTGTCGGGGGTG
  AAAGTCTACACCTTTGATGAGAGGATAGAGATTGATGCAGCACTCCTGACTTCTCAGCCC
  CACAGTCCCTTGTGCTCTGGCTGCAGGCCTGTGAGGTACCAGGTTCTCCGCGATCCCCCA
  TTTGCCAGTGGTTTGCCCGTGGTGGTGACACATTCTCACAGGAAGTTCACGGACGTGGAG
  GTCACACCTGGACAGATGTATCAGTACCAAGTTCTAGCTGAAGCTGGAGGAGAACTGGGA
  GAAGCTTCGCCTCCTCTGAACCACATTCATGGAGCTCCTTATTGTGGAGATGGGAAGGTG
  TCAGAGAGACTGGGAGAAGAGTGTGATGATGGAGACCTTGTGAGCGGAGATGGCTGCTCC
  AAGGTGTGTGAGCTGGAGGAAGGTTTCAACTGTGTAGGAGAGCCAAGCCTTTGCTACATG
  TATGAGGGAGATGGCATATGTGAACCTTTTGAGAGAAAAACCAGCATTGTAGACTGTGGC
  ATCTACACTCCCAAAGGATACTTGGATCAATGGGCTACCCGGGCTTACTCCTCTCATGAA
  GACAAGAAGAAGTGTCCTGTTTCCTTGGTAACTGGAGAACCTCATTCCCTAATTTGCACA
  TCATACCATCCAGATTTACCCAACCACCGTCCCCTAACTGGCTGGTTTCCCTGTGTTGCC
  AGTGAAAATGAAACTCAGGATGACAGGAGTGAACAGCCAGAAGGTAGCCTGAAGAAAGAG
  GATGAGGTTTGGCTCAAAGTGTGTTTCAATAGACCAGGAGAGGCCAGAGCAATTTTTATT
  TTTTTGACAACTGATGGCCTAGTTCCCGGAGAGCATCAGCAGCCGACAGTGACTCTCTAC
  CTGACCGATGTCCGTGGAAGCAACCACTCTCTTGGAACCTATGGACTGTCATGCCAGCAT
  AATCCACTGATTATCAATGTGACCCATCACCAGAATGTCCTTTTCCACCATACCACCTCA
  GTGCTGCTGAATTTCTCATCCCCACGGGTCGGCATCTCAGCTGTGGCTCTAAGGACATCC
  TCCCGCATTGGTCTTTCGGCTCCCAGTAACTGCATCTCAGAGGACGAGGGGCAGAATCAT
  CAGGGACAGAGCTGTATCCATCGGCCCTGTGGGAAGCAGGACAGCTGTCCGTCATTGCTG
  CTTGATCATGCTGATGTGGTGAACTGTACCTCTATAGGCCCAGGTCTCATGAAGTGTGCT
  ATCACTTGTCAAAGGGGATTTGCCCTTCAGGCCAGCAGTGGGCAGTACATCAGGCCCATG
  CAGAAGGAAATTCTGCTCACATGTTCTTCTGGGCACTGGGACCAGAATGTGAGCTGCCTT
  CCCGTGGACTGCGGTGTTCCCGACCCGTCTTTGGTGAACTATGCAAACTTCTCCTGCTCA
  GAGGGAACCAAATTTCTGAAACGCTGCTCAATCTCTTGTGTCCCACCAGCCAAGCTGCAA
  GGACTGAGCCCATGGCTGACATGTCTTGAAGATGGTCTCTGGTCTCTCCCTGAAGTCTAC
  TGCAAGTTGGAGTGTGATGCTCCCCCTATTATTCTGAATGCCAACTTGCTCCTGCCTCAC
  TGCCTCCAGGACAACCACGACGTGGGCACCATCTGCAAATATGAATGCAAACCAGGGTAC
  TATGTGGCAGAAAGTGCAGAGGGTAAAGTCAGGAACAAGCTCCTGAAGATACAATGCCTG
  GAAGGTGGAATCTGGGAGCAAGGCAGCTGCATTCCTGTGGTGTGTGAGCCACCCCCTCCT
  GTGTTTGAAGGCATGTATGAATGTACCAATGGCTTCAGCCTGGACAGCCAGTGTGTGCTC
  AACTGTAACCAGGAACGTGAAAAGCTTCCCATCCTCTGCACTAAAGAGGGCCTGTGGACC
  CAGGAGTTTAAGTTGTGTGAGAATCTGCAAGGAGAATGCCCACCACCCCCCTCAGAGCTG
  AATTCTGTGGAGTACAAATGTGAACAAGGATATGGGATTGGTGCAGTGTGTTCCCCATTG
  TGTGTAATCCCCCCCAGTGACCCCGTGATGCTACCTGAGAATATCACTGCTGACACTCTG
  GAGCACTGGATGGAACCTGTCAAAGTCCAGAGCATTGTGTGCACTGGCCGGCGTCAATGG
  CACCCAGACCCCGTCTTAGTCCACTGCATCCAGTCATGTGAGCCCTTCCAAGCAGATGGT
  TGGTGTGACACTATCAACAACCGAGCCTACTGCCACTATGACGGGGGAGACTGCTGCTCT
  TCCACACTCTCCTCCAAGAAGGTCATTCCATTTGCTGCTGACTGTGACCTGGATGAGTGC
  ACCTGCCGGGACCCCAAGGCAGAAGAAAATCAGTAA
  
  Clone variation with respect to NM_020318.2
  
• Restriction Sites: Please inquire
• ACCN: NM_020318
• ORF Size: 5373 bp
• Insert Size: 10000
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: A TrueClone.

Reference Data

• RefSeq: NM_020318.1, NP_064714.1
• RefSeq Size: 6940
• RefSeq ORF: 5373
• Locus ID: 60676
• Protein Families: Protease, Secreted Protein
• Gene Summary: This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
  Transcript Variant: This variant (1) encodes the longer isoform (1).