SH2D1B (NM_053282) Human Untagged Clone

CAT#: SC125856

SH2D1B (untagged)-Human SH2 domain containing 1B (SH2D1B)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SH2D1B
• Synonyms: EAT2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_053282 edited
  GTAGCTCCACAGGAGGTACAGCTGCTTACACATCTCTCCTCAGAGCTGTCCCTTGACTTG
  GGGGTGAATTTCAGGCCAACAGGGCTTCCTGGGATACAAGAGCGTTCTCCATGGATCTGC
  CTTACTACCATGGACGTCTGACCAAGCAAGACTGTGAGACCTTGCTGCTCAAGGAAGGGG
  TGGATGGCAACTTTCTTTTAAGAGACAGCGAGTCGATACCAGGAGTCCTGTGCCTCTGTG
  TCTCGTTTAAAAATATTGTCTACACATACCGAATCTTCAGAGAGAAACACGGGTATTACA
  GGATACAGACTGCAGAAGGTTCTCCAAAACAGGTCTTTCCAAGCCTAAAGGAACTGATCT
  CCAAATTTGAAAAACCAAATCAGGGGATGGTGGTTCACCTTTTAAAGCCAATAAAGAGAA
  CCAGCCCCAGCTTGAGATGGAGAGGATTGAAATTAGAGTTGGAAACATTTGTGAACAGTA
  ACAGCGATTATGTGGATGTCTTGCCTTAAAGATAAGGCTGCCGGACAAAGCAAGTTGAAG
  AGATGAGTAACAGTTCTCACTGATGACCCACTTCTGCAGGCATAGGTCCAGAGCACCAAA
  CTCTAGTGGACAATTCAGACTCTCCTGGTTGTGTAACTGAAGATGTTCTGCCCACCAGCA
  CCAGAGGTCACTCTCCACATCCCCGCCTCCCAGACATATACCAGGAGCAATTTCAAAACC
  CTCTCCAGTTTCACTCTTCTTTCTTGGAATGGGACAGCCTGAACATTTTCCCTTTGACTT
  GTTAAAGGTACCACCCTACATCATGGTTGACACCCTCCTTTGGACCATGCAGTCAGAGGG
  GCAGCTTTATACAGAGGAGGGGCACACTTGTCTGTGAGTTTGAAGCCCTGAGTTCCAGTC
  CTGTGGCTGTGTGACTTTGGACACGTTTCTGCCCATCTCCAGGTCTTAGTTTCTTTGTCT
  CTGTGGTTGGGTGGGATGATAAACATTGCCCCAGTCTCTCTGTTGAGCCTGCTTGTGTCA
  GGTGAAGGTGAGGGATCGGGAGTGATGGAGATGCATACAGATCAGCACCTTCTCTGTACC
  TGCTGGACCCCCATGTGCACCCTTCTCCCTCCAGCCTGGGCTACTCTCCTCCTGGTTCTT
  TCTAATCTTAAACTTCCTGGTGAGCATTGCCCCAGCCACACTTTCTCCCTGGTTTTGCTT
  AATTCCACTTATGCATCAGTCATTTCAACAGCATGAATGTGGTTCTGTACAGTGATGTAT
  GTGGAGATTTCTAAAATATTCTATGTGTGATTTCTGTTCCCAACTAGGTTCTAAGTGCCA
  TCAAAGCACGGTTGGGTCTCCCTTGTATCTTCCACAGTGTGTAGAAATTTGTGCTGCCCA
  GAGCTGTGCCTAGTTCATAGAAACTGACTGGAAGCACATTGCTGAGGGAGGTTTGTTGAA
  TTGGTTTTTAAGGTTTATTGAAATTGATTTGCTGAATTTTTCTGCTAGTTCAAAATGTGA
  ATTAGGACCTGGTCAGTTTGAAATATACCAAATTCTATGCCCTTTCTCTTACCTATCATC
  AAATTGTAGTAATGTATTTCACCCCACTGGACTTATCTTCAGAGTTTTAAAAGAGAGGAG
  CTCTCGACTTAGAGGTAATATGAACAGATGAACAGACACTGTGGCTGGAGCCCCAAAGTG
  TGGAGCATTGTGAGATTTGGGGTCACAGCAATTTATGGCTACTATTCCCTGGGTCTGGTA
  GGTAGGACAAATGTCCTCTTTTACTTTTCAAAACTGGCTTAGGTATTCATGGACCTTGAT
  TCTTCTATATACATTTTATAATAAATACGTGAAATTGCTTAAAACCTCTTTTTGGAATTT
  TTAATGAACTTGCAACAAATTTGTAAATAGGAGAGAACTGACGTTCTTGTGATGTTTTCC
  CATGCATAAACATGCCACATCCATGTTCTTGGGTCATCTTTTTTGCCCTTTCATGGAGTC
  ATAAATTTTCCCAACTGAAGTCTTGTATATTCTGTTAGATTAATTCCTATTTCTAGTTGC
  TGTAAATGATATCTTATGTTTTATTACATTTCTAATAGGATATGGTGTTGGTGAAATGTT
  AACCCTCTCATTAGATCTACTAGTTTACCTGTTGATTCTATTGTGTTTTCTATGTAAATG
  ATTTTGTCAGCTATAAATAATAACATTTTATTTTCTCTTTCCTTGCAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_053282 unedited
  GGTTCGGATTTGTATACGACTTTTATAGGCGGCCGCGTAATTCGCCATTACGGCCGGGGG
  TAGCTCCACAGAGGTACAGCTGCTTACACATCTCTCCTCAGAGCTGTCCCTTGACTTGGG
  GGTGAATTTCAGGCCAACAGGGCTTCCTGGGATACAAGAGCGTTCTCCATGGATCTGCCT
  TACTACCATGGACGTCTGACCAAGCAAGACTGTGAGACCTTGCTGCTCAAGGAAGGGGTG
  GATGGCAACTTTCTTTTAAGAGACAGCGAGTCGATACCAGGAGTCCTGTGCCTCTGTGTC
  TCGTTTAAAAATATTGTCTACACATACCGAATCTTCAGAGAGAAACACGGGTATTACAGG
  ATACAGACTGCAGAAGGTTCTCCAAAACAGGTCTTTCCAAGCCTAAAGGAACTGATCTCC
  AAATTTGAAAAACCAAATCAGGGGATGGTGGTTCACCTTTTAAAGCCAATAAAGAGAACC
  AGCCCCAGCTTGAGATGGAGAGGATTGAAATTAGAGTTGGAAACATTTGTGAACAGTAAC
  AGCGATTATGTGGATGTCTTGCCTTANAGATAAGGCTGCCGGACAAAGCAAGTTGAAGAG
  ATGAGTAACAGTTCTCACTGATGACCCACTTCTGCAGGCATAGGTCCAGAGCACCAAACT
  CTAGTGGACAATTCAGACTCTCCTGGTTGTGTAACTGAAGATGTTCTGCCCACCAGCACC
  AGGAGTCACTCTCCACATCCCCGCCTCCCAGACATATACCAGGNAGCAATTTCAAAACCC
  TCTCCAGTTTCACTCCTCTTTTCTGGAAATGGGACAGCCTGAACATTTTTCCCTTTGACC
  TGTTAAAGGTACCCCCCTACTTATGGTTGACACCCCCCTTGTGACATGCCTTCAAAGGGC
  ACCTTATACAAAGGAGGGCCCACTTTTCTTTAATTTGAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_053282
• ORF Size: 399 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_053282.4, NP_444512.2
• RefSeq Size: 2553
• RefSeq ORF: 399
• Locus ID: 117157
• Protein Pathways: Natural killer cell mediated cytotoxicity
• Gene Summary: By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]). [supplied by OMIM, Mar 2008]