AMH (NM_000479) Human Untagged Clone

CAT#: SC126077

AMH (untagged)-Human anti-Mullerian hormone (AMH)


  "NM_000479" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol AMH
Synonyms MIF; MIS
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_000479 edited
CCAGCCCCTGGCAGCACCCACGATGCGGGACCTGCCTCTCACCAGCCTGGCCCTAGTGCT
GTCTGCCCTGGGGGCTCTGCTGGGGACTGAGGCCCTCAGAGCAGAGGAGCCAGCTGTGGG
CACCAGTGGCCTCATCTTCCGAGAAGACTTGGACTGGCCTCCAGGCAGCCCACAAGAGCC
TCTGTGCCTGGTGGCACTGGGCGGGGACAGCAATGGCAGCAGCTCCCCCCTGCGGGTGGT
GGGGGCTCTAAGCGCCTATGAGCAGGCCTTCCTGGGGGCCGTGCAGAGGGCCCGCTGGGG
CCCCCGAGACCTGGCCACCTTCGGGGTCTGCAACACCGGTGACAGGCAGGCTGCCTTGCC
CTCTCTACGGCGGCTGGGGGCCTGGCTGCGGGACCCTGGGGGGCAGCGCCTGGTGGTCCT
ACACCTGGAGGAAGTGACCTGGGAGCCAACACCCTCGCTGAGGTTCCAGGAGCCCCCGCC
TGGAGGAGCTGGCCCCCCAGAGCTGGCGCTGCTGGTGCTGTACCCTGGGCCTGGCCCTGA
GGTCACTGTGACGAGGGCTGGGCTGCCAGGTGCCCAGAGCCTCTGCCCCTCCCGAGACAC
CCGCTACCTGGTGTTAGCGGTGGACCGCCCTGCGGGGGCCTGGCGCGGCTCCGGGCTGGC
CTTGACCCTGCAGCCCCGCGGAGAGGACTCCCGGCTGAGTACCGCCCGGCTGCAGGCACT
GCTGTTCGGCGACGACCACCGCTGCTTCACACGGATGACCCCGGCCCTGCTCCTGCTGCC
GCGGTCCGAGCCCGCGCCGCTGCCTGCGCACGGCCAGCTGGACACCGTGCCCTTCCCGCC
GCCCAGGCCATCCGCGGAACTCGAGGAGTCGCCACCCAGCGCAGACCCCTTCCTGGAGAC
GCTCACGCGCCTGGTGCGGGCGCTGCGGGTCCCCCCGGCCCGGGCCTCCGCGCCGCGCCT
GGCCCTGGATCCGGACGCGCTGGCCGGCTTCCCGCAGGGCCTAGTCAACCTGTCGGACCC
CGCGGCGCTGGAGCGCCTACTCGACGGCGAGGAGCCGCTGCTGCTGCTGCTGAGGCCCAC
TGCGGCCACCACCGGGGATCCTGCGCCCCTGCACGACCCCACGTCGGCGCCGTGGGCCAC
GGCCCTGGCGCGCCGCGTGGCTGCTGAACTGCAAGCGGCGGCTGCCGAGCTGCGAAGCCT
CCCGGGTCTGCCTCCGGCCACAGCCCCGCTGCTGGCGCGCCTGCTCGCGCTCTGCCCAGG
AGGCCCCGGCGGCCTCGGCGATCCCCTGCGAGCGCTGCTGCTCCTGAAGGCGCTGCAGGG
CCTGCGCGTGGAGTGGCGCGGGCGGGATCCGCGCGGGCCGGGTCGGGCACAGCGCAGCGC
GGGGGCCACCGCCGCCGACGGGCCGTGCGCGCTGCGCGAGCTCAGCGTAGACCTCCGCGC
CGAGCGCTCCGTACTCATCCCCGAGACCTACCAGGCCAACAATTGCCAGGGCGTGTGCGG
CTGGCCTCAGTCCGACCGCAACCCGCGCTACGGCAACCACGTGGTGCTGCTGCTGAAGAT
GCAGGCCCGTGGGGCCGCCCTGGCGCGCCCACCCTGCTGCGTGCCCACCGCCTACGCGGG
CAAGCTGCTCATCAGCCTGTCGGAGGAGCGCATCAGCGCGCACCACGTGCCCAACATGGT
GGCCACCGAGTGTGGCTGCCGGTGACCCCTGCGCCGCGCGGACTCCTGCCCCGAGGGTCC
GGACGCGCCCCAGCTCGCGCCCCTTCCCATATTTATTCGGACCCCAAGCATCGCCCCAAT
AAAGACCAGCAAGCAACCGGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAA
>OriGene 5' read for NM_000479 unedited
NGGCCGTTCAAATTTGTATACGACTCATATAGGCGGCCGCGATTCATTCTGGTACCGGTC
CGGAATTCCCGGGATCCAGCCCCTGGCAGCACCCACGATGCGGGACCTGCCTCTCACCAG
CCTGGCCCTAGTGCTGTCTGCCCTGGGGGCTCTGCTGGGGACTGAGGCCCTCAGAGCAGA
GGAGCCAGCTGTGGGCACCAGTGGCCTCATCTTCCGAGAAGACTTGGACTGGCCTCCAGG
CAGCCCACAAGAGCCTCTGTGCCTGGTGGCACTGGGCGGGGACAGCAATGGCAGCAGCTC
CCCCCTGCGGGTGGTGGGGGCTCTAAGCGCCTATGAGCAGGCCTTCCTGGGGGCCGTGCA
GAGGGCCCGCTGGGGCCCCCGAGACCTGGCCACCTTCGGGGTCTGCAACACCGGTGACAG
GCAGGCTGCCTTGCCCTCTCTACGGCGGCTGGGGGCCTGGCTGCGGGACCCTGGGGGGCA
GCGCCTGGTGGTCCTACACCTGGAGGAAGTGACCTGNGAGCCAACACCCTCGCTGAGGTT
CCAGGAGCCCCCGCCTGGAGGAGCTGGCCCCCCAGAGCTGGCGCTGCTGGTGCTGTACCC
TGGGCCTGGCCCTGAGGTCACTGTGACGAGGGCTGGGCTGCCAGGTGCCCAGAGCCTCTG
CCCCTCCCGAGACACCCGCTACCTGGTGTTAGCGGTGGACCGCCTTGGCGGGGGCCTGGC
GCGGCTCCGGGCTGGCCTTGACCCTGCAGCCCCGCGGAGAGGACTCCCGGCTGAGTACCG
CCCGGCTGCAGGCACTGCTGTTCCGCGACGACCACCGCTGCTTCCACGGATGACCCCCGC
CCTGCTCCTGCTGCCGCNG
Restriction Sites NotI-NotI     
ACCN NM_000479
ORF Size 1683 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_000479.2, NP_000470.1
RefSeq Size 2008
RefSeq ORF 1683
Locus ID 268
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
Gene Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]

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