SPAG6 (NM_172242) Human Untagged Clone

CAT#: SC126211

SPAG6 (untagged)-Human sperm associated antigen 6 (SPAG6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPAG6
• Synonyms: CT141; pf16; Repro-SA-1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_172242 edited
  GAGTAGCGGCTCCCGTCGGAGGCCGAGTCGTCGCCACGATCGCCCCCTTGGTGGACTCGC
  AGGCCGAGCGGCTTCCCCGCAGAGCTCGAGGAGGGCAGACGGCGGCGGGGGCGCCATGAG
  TCAGAGGCAGGTGCTGCAAGTGTTCGAGCAATACCAGAAGGCCAGGACCCAGTTCGTGCA
  GATGGTGGCGGAGCTGGCGACTAGACCCCAAAACATCGAGACGCTGCAGAACGCGGGTGT
  AATGTCTTTGCTGAGAACTCTTCTTCTGGACGTGGTCCCAACAATTCAACAGATTGCTGC
  TTTGGCTCTTGGGAGACTGGCCAATTATAATGATGACCTAGCAGAAGCTGTTGTGAAGTG
  CGACATTCTTCCACAGCTTGTTTATTCATTGGCAGAACAGAATCGCTTCTACAAGAAAGC
  AGCTGCCTTTGTGTTACGAGCAGTTGGTAAACATTCTCCCCAGCTAGCTCAGGCAATAGT
  CGATTGTGGAGCACTGGATACGCTGGTCATATGCTTGGAAGATTTTGACCCTGGAGTCAA
  GGAGGCTGCAGCCTGGGCACTTAGATATATTGCAAGACATAATGCAGAACTGTCACAAGC
  TGTGGTGGATGCAGGAGCTGTTCCTCTTTTAGTACTCTGTATCCAGGAGCCAGAAATTGC
  TTTGAAAGGGATTGCTGCTTCGGCCCTCAGTGATATTGTAAAGCATTCTCCAGAGTTAGC
  ACAGACAGTAGTGGATGCAGGAGCTGTTGCTCATTTAGCCCAGATGATCCTGAACCCTGA
  TGCTAAATTGAAGCATCAGATCCTTTCAGCTCTCAGTCAGGTTTCAAAACATTCCGTGGA
  TCTGGCAGAAATGGTTGTTGAAGCAGAGATTTTTCCAGTTGTACTTACCTGTCTGAAGGA
  CAAGGATGAATACGTGAAGAAAAATGCTTCTACTTTAATTAGAGAGATTGCAAAACATAC
  ACCCGAGCTTTCACAGCTGGTAGTTAACGCAGGAGGGGTTGCTGCCGTGATTGACTGCAT
  TGGGTCCTGCAAAGGGAACACACGGCTGCCTGGCATCATGATGCTTGGTTATGTAGCAGC
  TCATTCTGAGAACCTAGCAATGGCAGTCATCATTTCTAAGGGTGTACCCCAGTTGTCAGT
  CTGCTTGTCAGAAGAACCGGAAGATCATATTAAGGCTGCAGCTGCTTGGGCCTTAGGACA
  GATTGGAAGACACACTCCTGAACACGCACGGGCTGTTGCAGTCACAAATACTTTGCCAGT
  TCTGCTTTCTTTGTACATGTCAACAGAAAGTTCTGAGGATCTCCAAGTAAAAAGTAAAAA
  AGCCATAAAGAATATCCTGCAAAAATGTACCTACTTACCAGCCCTTGAACCATTTCTATA
  TGATGCTCCTCCCAATATTCTGAAACATGTGGTTGGACAGTTCAGTAAGGTATTATTCCC
  CTGGATATTCAGATACACTTCTGCGGAGGGTGGACAGCTATCAACCACTTAATAACTGAG
  CAAAGTTATATTGTGATACTCAAATTCACAGCAGAGTAGTTTTGAGTAACAGTAATTAAA
  TCCTTCTAAATATTTGAACTAAGTATATTCTAGATTTATTTAATGGGAAATACCTTTAGA
  TAATATTTTCTAAATTTATGTAATACTTTAAACATTCGTAGCTTGAATATGTGAGGAACT
  ATTCATGGTCATTCGCATGCATAGGATTTGTTCTACAGGTAGATTTTAAAAACACGTTAA
  AGGGCCTTAAGGCATTTTGTTATTCTGTTAAAAACCACACACACTCGTACATGCAGACAC
  CTCCAATGAGATATAGTTAAGAGATGGCATTCAAAAACCCTAAATTATTCTAGCCAATTT
  GTCATAGGCATAGGCAAGGAAAGCTGGCCTTGCTAACTATATAGTAGTATACACAAGAGA
  AATCTTTGAAGGAGGAAACTGATGACAGATATACAGGGCACTTGAAGGAGACTCTGATGC
  TAGTTATATAAGTGCATTAACTTAAGACACGGACTCTGTGGGTAACCTGTTAGGTTTTAC
  TAAGAATTTAGGAAAAATTTACTCCTCTTTATCACAAGTTTTCCAAACCTCCTTCCCCAC
  CCTATCTAAAGTGTTCCTTACCTTTCATGGGCCCAGCGAGGGTAGAATTCAGAATAGAGA
  GTTATACTCCTGCATACATGCTCTCCCTCTCATTGAAAGGTTTCTTAGTCTAGCTCTGCT
  CATGAATGAACAAAGAAGCAGGCATGTAAAATGGATCCTTGTCCTAACGTCACTTTCCCA
  AGTTTCAAAAGTCACATTTTCAGGTATTTAAGGAATAGTTTGAAGCTAATACCATCAGGC
  TCAGAGTTTACATGCATTTTTACTTAGGAAGTGGTAAACGGGTGAAAGAGGGTTTCAATA
  AAATTTTAAATAAAAACAGCAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_172242 unedited
  GTGCGGTCAGATTTTGTATACCATCATATAGGCGGCCGCATAACTTCGTATAGCATACAT
  TATACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGGAGTA
  GCGGCTCCCGTCGGAGGCCGAGTCGTCGCCACGATCGCCCCCTTGGTGGACTCGCAGGCC
  GAGCGGCTTCCCCGCAGAGCTCGAGGAGGGCAGACGGCGGCGGGGGCGCCATGAGTCAGA
  GGCAGGTGCTGCAAGTGTTCGAGCAATACCAGAAGGCCAGGACCCAGTTCGTGCAGATGG
  TGGCGGAGCTGGCGACTAGACCCCAAAACATCGAGACGCTGCAGAACGCGGGTGTAATGT
  CTTTGCTGAGAACTCTTCTTCTGGACGTGGTCCCAACAATTCAACAGATTGCTGCTTTGG
  CTCTTGGGAGACTGGCCAATTATAATGATGACCTAGCAGAAGCTGTTGTGAAGTGCGACA
  TTCTTCCACAGCTTGTTTATTCATTGGCAGAACAGAATCGCTTCTACTAGAAAGCAGCTG
  ACTTTGTGTTACGAGCAGTTGGTAAACATTCTCCCCAGCTAGCTCAGGCAATAGTCGATT
  GTGGAGCACTGGATACGCTGGTCATATGCTTGGAAGATTTTGACCCTGGAGTCAAGGAGG
  CTGCACCCCGGGCACTTAGATATATTGCAAGACATAAAGCAGAACTGTCACACACTGTGG
  TGGATGCAGGAGCTGTTCCTCCTTTAACACTCTGTATCCACGAGCCAGAAACTGCTTGAA
  AGGGATTGCAGGTTTGGCCCTCAATGAAAGTGAAAAGCCTCCCCAAAGTTGCACACCCGA
  TTGTTGGATCCGGAGCTGCTGCTCATTTTTCCCAAAGATCCCGAACCCAGAGCATAANTT
  G
  
• Restriction Sites: Please inquire
• ACCN: NM_172242
• ORF Size: 1377 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_172242.1, NP_758442.1
• RefSeq Size: 2463
• RefSeq ORF: 1377
• Locus ID: 9576
• Gene Summary: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2) that has a distinct C-terminus, compared to isoform 1.