NADPH oxidase 4 (NOX4) (BC040105) Human Untagged Clone

CAT#: SC126416

NOX4 (untagged)-Human NADPH oxidase 4, mRNA (cDNA clone MGC:48663 IMAGE:5590269), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NOX4
• Synonyms: kidney superoxide-producing NADPH oxidase; KOX; KOX-1; NADPH oxidase 4; renal NAD(P)H-oxidase; RENOX
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC040105 edited
  CCGCTGCCCCGGCCGCCGCCCGCTCCTTCTCGGTCCGGCGGGCACAGAGCGCAGCGCGGC
  GGGGCCGGCGGCATGGCTGTGTCCTGGAGGAGCTGGCTCGCCAACGAAGGGGTTAAACAC
  CTCTGCCTGTTCATCTGGCTCTCCATGAATGTCCTGCTTTTCTGGAAAACCTTCTTGCTG
  TATAACCAAGGGCCAGAGTATCACTACCTCCACCAGATGTTGGGGCTAGGATTGTGTCTA
  AGCAGAGCCTCAGCATCTGTTCTTAACCTCAACTGCAGCCTTATCCTTTTACCCATGTGC
  CGAACACTCTTGGCTTACCTCCGAGGATCACAGAAGGTTCCAAGCAGGAGAACCAGGAGA
  TTGTTGGATAAAAGCAGAACATTCCATATTACCTGTGGTGTTACTATCTGTATTTTCTCA
  GGCGTGCATGTGGCTGCCCATCTGGTGAATGCCCTCAACTTCTCAGTGAATTACAGTGAA
  GACTTTGTTGAACTGAATGCAGCAAGATACCGAGATGAGGATCCTAGAAAACTTCTCTTC
  ACAACTGTTCCTGGCCTGACAGGGGTCTGCATGGTGGTGGTGCTATTCCTCATGATCACA
  GCCTCTACATATGCAATAAGAGTTTCTAACTATGATATCTTCTGGTATACTCATAACCTC
  TTCTTTGTCTTCTACATGCTGCTGACGTTGCATGTTTCAGGAGGGCTGCTGAAGTATCAA
  ACTAATTTAGATACCCACCCTCCCGGCTGCATCAGTCTTAACCGAACCAGCTCTCAGAAT
  ATTTCCTTACCAGAGTATTTCTCAGAACATTTTCATGAACCTTTCCCTGAAGGATTTTCA
  AAACCGGCAGAGTTTACCCAGCACAAATTTGTGAAGATTTGTATGGAAGAGCCCAGATTC
  CAAGCTAATTTTCCACAGACTTGGCTTTGGATTTCTGGACCTTTGTGCCTGTACTGTGCC
  GAAAGACTTTACAGGTATATCCGGAGCAATAAGCCAGTCACCATCATTTCGGTCATAAGT
  CATCCCTCAGATGTCATGGAAATCCGAATGGTCAAAGAAAATTTTAAAGCAAGACCTGGT
  CAGTATATTACTCTACATTGTCCCAGTGTATCTGCATTAGAAAATCATCCATTTACCCTC
  ACAATGTGTCCAACTGAAACCAAAGCAACATTTGGGGTTCATCTTAAAATAGTAGGAGAC
  TGGACAGAACGATTTCGAGATTTACTACTGCCTCCATCTAGTCAAGACTCCGAAATTCTG
  CCCTTCATTCAATCTAGAAATTATCCCAAGCTGTATATTGATGGTCCTTTTGGAAGTCCA
  TTTGAGGAATCACTGAACTATGAGGTCAGCCTCTGCGTGGCTGGAGGCATTGGAGTAACT
  CCATTTGCATCAATACTCAACACCCTGTTGGATGACTGGAAACCATACAAGCTTAGAAGA
  CTATACTTTATTTGGGTATGCAGAGATATCCAGTCCTTCCGTTGGTTTGCAGATTTACTC
  TGTATGTTGCATAACAAGTTTTGGCAAGAGAACAGACCTGACTATGTCAACATCCAGCTG
  TACCTCAGTCAAACAGATGGGATACAGAAGATAATTGGAGAAAAATATCATGCACTGAAT
  TCAAGACTGTTTATAGGACGTCCTCGGTGGAAACTTTTGTTTGATGAAATAGCAAAATAT
  AACAGAGGAAAAACAGTTGGTGTTTTCTGTTGTGGACCCAATTCACTATCCAAGACTCTT
  CATAAACTGAGTAACCAGAACAACTCATATGGGACAAGATTTGAATACAATAAAGAGTCT
  TTCAGCTGAAAACTTTTGCCATGAAGCAGGACTCTAAAGAAGGAATGAGTGCAATTTCTA
  AGACTTTGAAACTCAGCGGAATCAATCAGCTGTGTTATGCCAAAGAATAGTAAGGTTTTC
  TTATTTATGATTATTTAAAATGGAAATGTGAGAATGTGGCAAGATGACCGTCACATTACA
  TGTTTAATCTGGAAACCAAAGAGACCCTGAAGAATATTTGATGTGATGATTCACTTTTCA
  GTTCTCAAATTAAAAGAAAACTGTTAGATGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC040105 unedited
  NNNNNGCGTTCANATTTTGTAATACGACTCACTATAGGGNNCGGCCGCGNAATTCAGTTN
  CTNNGGTACCGGTCCGGNAATTCCCGGGATCCGCTGCCCCGGCCGCCGCCCGCTCCTTCT
  CGGTCCGGCGGGCACAGAGCGCAGCGCGGCGGGGCCGGCGGCATGGCTGTGTCCTGGAGG
  AGCTGGCTCGCCAACGAAGGGGTTAAACACCTCTGCCTGTTCATCTGGCTCTCCATGAAT
  GTCCTGCTTTTCTGGAAAACCTTCTTGCTGTATAACCAAGGGCCAGAGTATCACTACCTC
  CACCAGATGTTGGGGCTAGGATTGTGTCTAAGCAGAGCCTCAGCATCTGTTCTTAACCTC
  AACTGCAGCCTTATCCTTTTACCCATGTGCCGAACACTCTTGGCTTACCTCCGAGGATCA
  CAGAAGGTTCCAAGCAGGAGAACCAGGAGATTGTTGGATAAAAGCAGAACATTCCATATT
  ACCTGTGGTGTTACTATCTGTATTTTCTCAGGCGTGCATGTGGCTGCCCATCTGGTGAAT
  GCCCTCAACTTCTCAGTGAATTACAGTGAAGACTTTGTTGAACTGAATGCAGCAAGATAC
  CGAGATGAGGATCCTAGAAAACTTCTCTTCACAACTGTTCCTGGCCTGACAGGGGTCTGC
  ATGGTGGTGGTGCTATTCCTCATGATCACAGCCTCTACATATGCAATAAGAGTTTCTAAC
  TATGAATATCTTCTGGTATACTCATAACCCTCTCTTTGTCTTCTACATGCTGCTGACGTT
  GCATGTTTCAGGAGGGCTGCTGAAGTATCAACTAATTAGATCCCACCCTTCCGGCTGCAT
  TAATCTTAACCGACCCGCTTTAA
  
• Restriction Sites: NotI-NotI
• ACCN: BC040105
• ORF Size: 1734 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC040105.1, AAH40105.1
• RefSeq Size: 2108
• RefSeq ORF: 1734
• Locus ID: 50507
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]