UBE2G2 (NM_182688) Human Untagged Clone

CAT#: SC126784

UBE2G2 (untagged)-Human ubiquitin-conjugating enzyme E2G 2 (UBE2G2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBE2G2
• Synonyms: UBC7
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126784 sequence for NM_182688 edited (data generated by NextGen Sequencing)
  ATGAATGAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAAGACACCTGC
  TTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTTCCCACTTGATTACCCGTTAAGTCCC
  CCAAAGATGAGATTTACCTGTGAGATGTTTCATCCCAACATCTACCCTGATGGGAGAGTC
  TGCATTTCCATCCTCCACGCGCCAGGCGATGACCCCATGGGCTACGAGAGCAGCGCGGAG
  CGGTGGAGTCCTGTGCAGAGTGTGGAGAAGATCCTGCTGTCGGTGGTGAGCATGCTGGCA
  GAGCCCAATGACGAAAGTGGAGCTAACGTGGATGCGTCCAAAATGTGGCGCGATGACCGG
  GAGCAGTTCTATAAGATTGCCAAGCAGATCGTCCAGAAGTCTCTGGGACTGTGA
  
  Clone variation with respect to NM_182688.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_182688 unedited
  CCCCCCCATACCCCCGCCCGTTGNCGCTTTGGGCGGTAGGCGTGTACGGTGGGAGGTCTA
  TATAAGCAGTTCTTATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGC
  GGCCGCGAATTCGGCACGAGGCACGCGCGCGGCTGAGGCGAGGTCGCTCGGCGCAGCTGT
  TGCGGGGCCATGGCGGGGACCGCGCTCAAGAGGCTGATGGCCGAGTACAAACAATTAACA
  CTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAATGAAGAGAACTTTTTTGAATGG
  GAGGCATTGATCATGGGCCCAGAAGACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATC
  CTGAGTTTCCCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGTGAGATG
  TTTCATCCCAACATCTACCCTGATGGGAGAGTCTGCATTTCCATCCTCCACGCGCCAGGC
  GATGACCCCATGGGCTACGAGAGCAGCGCGGAGCGGTGGAGTCCTGTGCAGAGTGTGGAG
  AAGATCCTGCTGTCGGTGGTGAGCATGCTGGCAGAGCCCAATGACGAAAGTGGAGCTAAC
  GTGGATGCGTCCAAAATGTGGCGCGATGACCGGGAGCAGTTCTATAAGAGTGCCAAGCAG
  ATCGTCCAGAAGTCTCTGGGACTGTGAGACCTGGCCTCGCACAGGCGCACACACACCGCC
  AATCAGCTCAGCATTCTCCCCCGGCACACTTAGTGACAGTGATGCTCTGTGCTGGTACCA
  AACTAGGCAGACTTGCAAGAACCCGGCATCTTTTTTTTTTTCAACCTTTCTACTTCAACA
  GGCTTCTCTTCTGAAAGGAGACTTAATGTCGAATATTGACAACTTACTGCAGTTNTACAG
  GA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_182688
• ORF Size: 414 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_182688.1, NP_872630.1
• RefSeq Size: 3034
• RefSeq ORF: 414
• Locus ID: 7327
• Protein Families: Druggable Genome
• Protein Pathways: Parkinson's disease, Ubiquitin mediated proteolysis
• Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
  Transcript Variant: This variant (2) has an additional exon in the 5' region, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) has a shorter N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.