ACSL1 (NM_001995) Human Untagged Clone

CAT#: SC126825

ACSL1 (untagged)-Human acyl-CoA synthetase long-chain family member 1 (ACSL1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACSL1
• Synonyms: ACS1; FACL1; FACL2; LACS; LACS1; LACS2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001995, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCAAGCCCATGAGCTGTTCCGGTATTTTCGAATGCCAGAGCTGGTTGACTTCCGACAGTACGTGCGTA
  CTCTTCCGACCAACACGCTTATGGGCTTCGGAGCTTTTGCAGCACTCACCACCTTCTGGTACGCCACGAG
  ACCCAAACCCCTGAAGCCGCCATGCGACCTCTCCATGCAGTCAGTGGAAGTGGCGGGTAGTGGTGGTGCA
  CGAAGATCCGCACTACTTGACAGCGACGAGCCCTTGGTGTATTTCTATGATGATGTCACAACATTATACG
  AAGGTTTCCAGAGGGGAATACAGGTGTCAAATAATGGCCCTTGTTTAGGCTCTCGGAAACCAGACCAACC
  CTATGAATGGCTTTCATATAAACAGGTTGCAGAATTGTCGGAGTGCATAGGCTCAGCACTGATCCAGAAG
  GGCTTCAAGACTGCCCCAGATCAGTTCATTGGCATCTTTGCTCAAAATAGACCTGAGTGGGTGATTATTG
  AACAAGGATGCTTTGCTTATTCGATGGTGATCGTTCCACTTTATGATACCCTTGGAAATGAAGCCATCAC
  GTACATAGTCAACAAAGCTGAACTCTCTCTGGTTTTTGTTGACAAGCCAGAGAAGGCCAAACTCTTATTA
  GAGGGTGTAGAAAATAAGTTAATACCAGGCCTTAAAATCATAGTTGTCATGGATGCCTACGGCAGTGAAC
  TGGTGGAACGAGGCCAGAGGTGTGGGGTGGAAGTCACCAGCATGAAGGCGATGGAGGACCTGGGAAGAGC
  CAACAGACGGAAGCCCAAGCCTCCAGCACCTGAAGATCTTGCAGTAATTTGTTTCACAAGTGGAACTACA
  GGCAACCCCAAAGGAGCAATGGTCACTCACCGAAACATAGTGAGCGATTGTTCAGCTTTTGTGAAAGCAA
  CAGAGAATACAGTCAATCCTTGCCCAGATGATACTTTGATATCTTTCTTGCCTCTCGCCCATATGTTTGA
  GAGAGTTGTAGAGTGTGTAATGCTGTGTCATGGAGCTAAAATCGGATTTTTCCAAGGAGATATCAGGCTG
  CTCATGGATGACCTCAAGGTGCTTCAACCCACTGTCTTCCCCGTGGTTCCAAGACTGCTGAACCGGATGT
  TTGACCGAATTTTCGGACAAGCAAACACCACGCTGAAGCGATGGCTCTTGGACTTTGCCTCCAAGAGGAA
  AGAAGCAGAGCTTCGCAGCGGCATCATCAGAAACAACAGCCTGTGGGACCGGCTGATCTTCCACAAAGTA
  CAGTCGAGCCTGGGCGGAAGAGTCCGGCTGATGGTGACAGGAGCCGCCCCGGTGTCTGCCACTGTGCTGA
  CGTTCCTCAGAGCAGCCCTGGGCTGTCAGTTTTATGAAGGATACGGACAGACAGAGTGCACTGCCGGGTG
  CTGCCTGACCATGCCTGGAGACTGGACCGCAGGCCATGTTGGGGCCCCGATGCCGTGCAATTTGATAAAA
  CTTGTTGATGTGGAAGAAATGAATTACATGGCTGCCGAGGGCGAGGGCGAGGTGTGTGTGAAAGGGCCAA
  ATGTATTTCAGGGCTACTTGAAGGACCCAGCGAAAACAGCAGAAGCTTTGGACAAAGACGGCTGGTTACA
  CACAGGGGACATTGGAAAATGGTTACCAAATGGCACCTTGAAAATTATCGACCGGAAAAAGCACATATTT
  AAGCTGGCACAAGGAGAATACATAGCCCCTGAAAAGATTGAAAATATCTACATGCGAAGTGAGCCTGTTG
  CTCAGGTGTTTGTCCACGGAGAAAGCCTGCAGGCATTTCTCATTGCAATTGTGGTACCAGATGTTGAGAC
  ATTATGTTCCTGGGCCCAAAAGAGAGGATTTGAAGGGTCGTTTGAGGAACTGTGCAGAAATAAGGATGTC
  AAAAAAGCTATCCTCGAAGATATGGTGAGACTTGGGAAGGATTCTGGTCTGAAACCATTTGAACAGGTCA
  AAGGCATCACATTGCACCCTGAATTATTTTCTATCGACAATGGCCTTCTGACTCCAACAATGAAGGCGAA
  AAGGCCAGAGCTGCGGAACTATTTCAGGTCGCAGATAGATGACCTCTATTCCACTATCAAGGTTTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001995 unedited
  AACCAGCGGGCCGAGGCGGCGGCGCCAGCGGCGCCTTAAATAGCATCCAGAGCCGGCGCG
  GGGCAGGGAGTGGGCTGCAGTGACAGCCGGCGGCGGAGCGGCCGGTCCACGGAGGAGAAT
  TCAGCTTAGAGAACTATCAACACAGGACAATGCAAGCCCATGAGCTGTTCCGGTATTTTC
  GAATGCCAGAGCTGGTTGACTTCCGACAGTACGTGCGTACTCTTCCGACCAACACGCTTA
  TGGGCTTCGGAGCTTTTGCAGCACTCACCACCTTCTGGTACGCCACGAGACCCAAACCCC
  TGAAGCCGCCATGCGACCTCTCCATGCAGTCAGTGGAAGTGGCGGGTAGTGGTGGTGCAC
  GAAGATCCGCACTACTTGACAGCGACGAGCCCTTGGTGTATTTCTATGATGATGTCACAA
  CATTATACGAAGGTTTCCAGAGGGGAATACAGGTGTCAAATAATGGCCCTTGTTTAGGCT
  CTCGGAAACCAGACCAACCCTATGAATGGCTNTCATATAAACAGGTTGCAGAATTGTCGG
  AGTGCATAGGCTCAGCACTGATCCAGAAGGGCTTCAAGACTGCCCCAGATCAGTTCATTG
  GCATCTTTGCTCAAATAGACCTGAGTGGGTGATTATTGAACAAGGATGCTTTGCTTATTC
  GATGGTGNATCGTCCACTTTATGATACCCTGGAAATGAAGCCTCACGTACATAGTCACAN
  AGCTGAACTCTCTCTGGTTTTTGTGACAGCCANGAGAAGGCAAACTCTATTANAGGGTGT
  ANAAAATAGTTAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001995 unedited
  TGGGGGCAAACTATCTCTTGGTTTCCTTAATTGCTTTTGGCAATTTTGTTTTGGTTTATA
  AAACATAGAAATAGCCAACACTCTAAAGCAAACATTCAAAACCCCAAGGTGACAAATTAT
  TGACTTTTTGTGCAATTAAGAATACATATATGAAGTTAGGCTACCAAGTAGTGTTATTAC
  AATGACAATTCTTTAGTGCAAGCCCTGTTGTGCTTGTATATAATACATGTACTCTCACAG
  ACCCCAAAACAGCTGCTTTAAATGTCCAAATGACAGCCTCACTTCAGTCAAATGTGGCAA
  AGACTCACAATAAAGTGAACTGCTGCTAATTTCCCAAATTAACTTTAAAAAATCCCTGTA
  GAAGTGACTTCCACGAAATGAACTTTCCAGATTCCTACATTCTACAATTTTGGCTTGTCA
  AACACATCTTATAGAAACCAGGTAGCATTATAAGAACATTTGCTCATTACTGTCCATTTC
  AATAACTACTCAAGCATATACTCCTTTTAATTAGCTCCAACGAAATGCTCGCCTGATAGT
  TTATCTTTTGGGGAAAAGGCAAGTTAATTCCCACATGATCTTCCGATCTGAAACCACATT
  CTAACTCTGCCGGCCTCTACATATAGCGAGTGCGCCACCCCCACACAAATTATTACGTTC
  TCTATGGTGCCACACCCTTACCCCGGCTGATCCACGGCATTCTCCTTTGAAATGCTTTGC
  CCCATCTTTCAATCCACATGCGATTCCCCCACACCCCCCCGTTATAGGATTGTTTCCTCC
  AATCCTCCCCTGCGAAATCCCCCCTCAGTCCCTTTTTTTTCCACCACCATCTTACCGTCC
  CCATTATCACTCATTGTCACAGGCTCCCATATTGATGGCTCCCCCGTCGGACCACTCTTT
  TTTTTATGTACCCCTCCCCTCTAACAATTTTCTTCGCCACCCGACCCCCCCCCTTTTTTT
  CACCTCCCCCCGCCCGCCTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001995
• ORF Size: 2097 bp
• Insert Size: 4310
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_001995.2, NP_001986.2
• RefSeq Size: 3822
• RefSeq ORF: 2097
• Locus ID: 2180
• Domains: AMP-binding
• Protein Families: Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway
• Gene Summary: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
  Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a).