B7H3 (CD276) (BC011578) Human Untagged Clone

CAT#: SC126836

(untagged)-Homo sapiens, clone MGC:20354 IMAGE:4548461, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD276
• Synonyms: 4Ig-B7-H3|B7-H3|B7H3|B7RP-2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for BC011578, the custom clone sequence may differ by one or more nucleotides
  
  
  CAGCCCTGCAGCCTCTGAAACACTCTGACAGCAAAGAAGATGATGGACAAGAAATAGCCTGACCATGAGG
  ACCAGGGAGCTGCTACCCCTCCCTACAGCTCCTACCCTCTGGCTGCAATGGGGCTGCACTGTGAGCCCTG
  CCCCCAACAGATGCATCCTGCTCTGACAGGTGGGCTCCTTCTCCAAAGGATGCGATACACAGACCACTGT
  GCAGCCTTATTTCTCCAATGGACATGATTCCCAAGTCATCCTGCTGCCTTTTTTTCTTATAGACACAATG
  AACAGACCACCCACAACCTTAGTTCTCTAAGTCATCCTGCCTGCTGCCTTATTTCACAGTACATACATTT
  CTTAGGGACACAGTACACTGACCACATCACCACCCTCTTCTTCCAGTGCTGCGTGGACCATCTGGCTGCC
  TTTTTTCTCCAAAAGATGCAATATTCAGACTGACTGACCCCCTGCCTTATTTCACCAAAGACACGATGCA
  TAGTCACCCCGGCCTTGTTTCTCCAATGGCCGTGATACACTAGTGATCATGTTCAGCCCTGCTTCCACCT
  GCATAGAATCTTTTCTTCTCAGACAGGGACAGTGCGGCCTCAACATCTCCTGGAGTCTAGAAGCTGTTTC
  CTTTCCCCTCCTTCCTCCTCTTGCTCTAGCCTTAATACTGGCCTTTTCCCTCCCTGCCCCAAGTGAAGAC
  AGGGCACTCTGCGCCCACCACATGCACAGCTGTGCATGGAGACCTGCAGGTGCACGTGCTGGAACACGTG
  TGGTTCCCCCCTGGCCCAGCCTCCTCTGCAGTGCCCCTCTCCCCTGCCCATCCTCCCCACGGAAGCATGT
  GCTGGTCACACTGGTTCTCCAGGGGTCTGTGATGGGGCCCCTGGGGGTCAGCTTCTGTCCCTCTGCCTTC
  TCACCTCTTTGTTCCTTTCTTTTCATGTATCCATTCAGTTGATGTTTATTGAGCAACTACAGATGTCAGC
  ACTGTGTTAGGTGCTGGGGGCCCTGCGTGGGAAGATAAAGTTCCTCCCTCAAGGACTCCCCATCCAGCTG
  GGAGACAGACAACTAACTACACTGCACCCTGCGGTTTGCAGGGGGCTCCTGCCTGGCTCCCTGCTCCACA
  CCTCCTCTGTGGCTCAAGGCTTCCTGGATACCTCACCCCCATCCCACCCATAATTCTTACCCAGAGCATG
  GGGTTGGGGCGGAAACCTGGAGAGAGGGACATAGCCCCTCGCCACGGCTAGAGAATCTGGTGGTGTCCAA
  AATGTCTGTCCAGGTGTGGGCAGGTGGGCAGGCACCAAGGCCCTCTGGACCTTTCATAGCAGCAGAAAAG
  GCAGAGCCTGGGGCAGGGCAGGGCCAGGAATGCTTTGGGGACACCGAGGGGACTGCCCCCCACCCCCACC
  ATGGTGCTATTCTGGGGCTGGGGCAGTCTTTTCCTGGCTTGCCTCTGGCCAGCTCCCGGCCTCTGGTAGA
  GTGAGACTTCAGACGTTCTGATGCCTTCCGGATGTCATCTCTCCCTGCCCCAGGAATGGAAGATGTGAGG
  ACTTCTAATTTAAATGTGGGACTCGGAGGGATTTTGTAAACTGGGGGTATATTTTGGGGAAAATAAATGT
  CTTTGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC011578 unedited
  CCGCGAAATTCGCACGAGGCCTCGTGCCGAATTCGGCACGAGGGTACACTGACCACATCA
  CCACCCTCTTCTTCCAGTGCTGCGTGGACCATCTGGCTGCCTTTTTTCTCCAAAAGATGC
  AATATTCAGACTGACTGACCCCCTGCCTTATTTCACCAAAGACACGATGCATAGTCACCC
  CGGCCTTGTTTCTCCAATGGCCGTGATACACTAGTGATCATGTTCAGCCCTGCTTCCACC
  TGCATAGAATCTTTTCTTCTCAGACAGGGACAGTGCGGCCTCAACATCTCCTGGAGTCTA
  GAAGCTGTTTCCTTTCCCCTCCTTCCTCCTCTTGCTCTAGCCTTAATACTGGCCTTTTCC
  CTCCCTGCCCCAAGTGAAGACAGGGCACTCTGCGCCCACCACATGCACAGCTGTGCATGG
  AGACCTGCAGGTGCACGTGCTGGAACACGTNGTGGTTCCCCCCTGGCCCAGCCTCCTCTG
  CAGTGCCCCTCTCCCCTGCCCATCCTCCCCACGGAAGCATGTGCTGGTCACACTGGTTCT
  CCAGGNGGTCTGTGATGGGGCCCCTGNGGGTCAGCTTCTGTCCCTCTGCCTTCTCACCTC
  TNTGTTCCTTTCTTTTCATGTATCCATTCAGTTGATGTTTATTGAGCCACTACAGATGTC
  AGCACTGTGTTAGGTGCTGGGGGCCCTGCGTGGGAGAATAAAGTTNCTNCCTCAGGNACT
  CCCCATNCAGCTGGGAGACAGACACTAACTACACTGACCCCTGGCGTTGGAGGGGGGTCC
  TGNCTGGCTCCCGGCTTCACACTTCTTTGTGGCTCAGGGCTTCTGGNATACCTACCCCCT
  TCCACCATTATTCTACCAAGATGGGGG
  
• Restriction Sites: NotI-NotI
• ACCN: BC011578
• ORF Size: 414 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC011578.1, AAH11578.1
• RefSeq Size: 1698
• RefSeq ORF: 414
• Locus ID: 80381
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]