GGA2 (NM_138640) Human Untagged Clone

CAT#: SC126986

GGA2 (untagged)-Human golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GGA2
• Synonyms: ADP-ribosylation factor binding protein 2; FLJ20966; golgi associated, gamma adaptin ear containing, ARF binding protein 2; KIAA1080; VEAR; VEAR, FLJ20966, KIAA1080; VHS domain and ear domain-containing protein
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_138640, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCGACCGCGGTGGCGGCGGCTGTGGCGGGAACCGAGTCGGCCCAGGGTCCCCCGGGCCCGGCAG
  CGTCGCTGGAGCTGTGGCTGAACAAAGCCACAGACCCAAGCATGTCGGAACAGGATTGGTCAGCTATCCA
  GAATTTCTGTGAGCAGGTGAACACTGACCCCAATGGCCCCACACATGCGCCCTGGCTACTGGCCCACAAG
  ATCCAGTCTCCGCAAGAGAAGGAAGCTCTTTATGCCTTAACGGTGCTGGAGATGTGCATGAACCACTGTG
  GGGAGAAGTTCCACAGCGAGGTGGCCAAATTTCGTTTCCTGAACGAACTGATCAAAGTGTTGTCCCCAAA
  GTACCTGGGGTCCTGGGCCACAGGAAAAGTTAAAGGAAGAGTCATTGAAATACTCTTCAGTTGGACAGTC
  TGGTTTCCGGAAGACATCAAGATTCGAGACGCTTATCAGATGCTGAAGAAACAAGGAATTATAAAACAAG
  ACCCTAAACTACCAGTGGATAAAATCTTACCCCCACCATCTCCCTGGCCCAAGAGCTCCATCTTTGATGC
  TGATGAAGAAAAGTCCAAGCTCTTTCTCAGTGCCAGTGAGCCCGGCCCTATCCATTTTCCATCCACCATG
  AACTCCCCAAACCGTTATTCCTTGGACATCAGTATCTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_138640 unedited
  GGAAGCGTCAAATTTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCCA
  GGACGCTACAGCGGCTGAAGAGGCAGTGGCGCCCGCGGCCGCAGCGTCGGGGCTGGAGCG
  ATGGCGGCGACCGCGGTGGCGGCGGCTGTGGCGGGAACCGAGTCGGCCCAGGGTCCCCCG
  GGCCCGGCAGCGTCGCTGGAGCTGTGGCTCAACAAAGCCACAGACCCAAGCATGTCGGAA
  CAGGATTGGTCAGCTATCCAGAATTTCTGTGAGCAGGTGAACACTGACCCCAATGGCCCC
  ACACATGCGCCCTGGCTACTGGCCCACAAGATCCAGTCTCCGCAAGAGAAGGAAGCTCTT
  TATGCCTTAACGGTGCTGGAGATGTGCATGAACCACTGTGGGGAGAAGTTCCACAGCGAG
  GTGGCCAAATTTCGTTTCCTGAACGAACTGATCAAAGTGTTGTCCCCAAAGTACCTGGGG
  TCCTGGGCCACAGGAAAAGTTAAAGGAAGAGTCATTGAAATACTCTTCAGTTGGACAGTC
  TGGTTTCCGGAAGACATCAAGATTCGAGACGCTTATCAGATGCTGAAGAAACAAGGAATT
  ATAAAACAAGACCCTAAACTACCAGTGGATAAAATCTTACCCCCACCATCTCCCTGGCCC
  AAGAGCTCCATCTTTGATGCTGATGAAGAAAAGTCCAAGCTTCTGACAAGGCTTCTAAAG
  AGCAACCACCCCGAGGACCTTCAGGCTGCAAACCGGTTAATCAAGAATTTGGTCAAGGAG
  GAACAAGAAAAATCGGAGAAGGTGTCCAAGAAGGTCAGTGCGGTGNGAGAAGTGCGAAGC
  CATGTGAAGGTGCTGCNAGAGATGCTGAGCATGTACCGCAGGCCAGGGCAGGCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_138640 unedited
  TTGGCCGCGGCCGCAATCTAGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTAAAATATCAGATTTTGGAATTAAAAGCTCCAAACAA
  GTTTTGCAGTTTCAAAGGGAAAAACCCACCCAGCCAGTTCAGTTGGTTGGACTTAAAAGC
  CCTCCGCCTAGCCATTTAAGCCAGGCTAAGGTTCCTTTTCCCACCCATCAGGCCAAGCAG
  GACTTGGCAAACATACACATTCAAGTTCCTAACACACAGTAGGGGCTAAGGGGGAATTGA
  TTATAAACTTGAATTTTTCCATCAACAAATATCCACCTTTCCTGTCCAGCTTGCCTAAAA
  TTTTAAGGTTTTTTTTTTTTTGAGGCAGCTAAGCTTCTACATCCTTCATGAAGTTTCCTT
  TACTTTTCGACAAAAAACAGTTCCCTTTAGGCCTATCATTTTTAAAGGCAACTGGTTTTC
  CATTTTCCACTTACTCAACACTCCACAAAGAACACTTGCTACATGGTATTTATTCAAGGA
  CTGGATATTTAGTCACCACCTCAATCACTGCTAAGCTCTCTTCATGGCTATCTGTACCAG
  TTTCCCATTTTAAACTGGGACGTCAACTGGCAAGGGCTGGTTGTTGGCCAATTCATCATG
  ACTGACATGGTGGGTCACAAAGAAGCCTCCATAAAATGCTGTGAAGGAAAAGGATGAGGA
  TGGAAATGAGGATCCTTGAAAAGCCCAATACTGGTTGCCCAACCATGGACCTGAGGCCTG
  AATAAGGCCTTGGAACTGTTTTCCCTTTTGCCAAGAACTTTGTCCAGGGGCGATTTAAAG
  GCCAAGGGGAGAAGCAATGATTGGCCCCCAGGGGGGGCCTCAGGTTTATGGCAGCCACTC
  CCTGGAGACGGGGCACAAGCATCCTATTAAAAAACTTCCACAAACCACACAAAACTTTGG
  TTATGAAAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_138640
• ORF Size: 669 bp
• Insert Size: 3630
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_138640.1, NP_619581.1
• RefSeq Size: 5078
• RefSeq ORF: 669
• Locus ID: 23062
• Domains: GAT, Alpha_adaptinC2
• Protein Pathways: Lysosome
• Gene Summary: This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) contains an additional exon between exons 6 and 7 and lacks a downstream sequence segment, as compared to the longer transcript variant 1. This variant encodes isoform 2 which includes an early in-frame stop codon, resulting in a truncated protein.