UBE2L6 (NM_198183) Human Untagged Clone

CAT#: SC126998

UBE2L6 (untagged)-Human ubiquitin-conjugating enzyme E2L 6 (UBE2L6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBE2L6
• Synonyms: RIG-B; UBCH8
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126998 sequence for NM_198183 edited (data generated by NextGen Sequencing)
  ATGATCAAATTCACAACCAAGATCTACCACCCCAACGTGGACGAGAACGGACAGATTTGC
  CTGCCCATCATCAGCAGTGAGAACTGGAAGCCTTGCACCAAGACTTGCCAAGTCCTGGAG
  GCCCTCAATGTGCTGGTGAATAGACCGAATATCAGGGAGCCCCTGCGGATGGACCTCGCT
  GACCTGCTGACACAGAATCCGGAGCTGTTCAGAAAGAATGCCGAAGAGTTCACCCTCCGA
  TTCGGAGTGGACCGGCCCTCCTAA
  
  Clone variation with respect to NM_198183.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_198183 unedited
  ATTTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCCACACACTCGG
  TCCCGACATGATGGCGAGCATGCGAGTGGTGAAGGAGCTGGAGGATCTTCAGAAGAAGCC
  TCCCCCATACCTGCGGAACCTGTCCAGCGATGATGCCAATGTCCTGGTGTGGCACGCTCT
  CCTCCTACCCGACCAACCTCCCTACCACCTGAAAGCCTTCAACCTGCGCATCAGCTTCCC
  GCCGGAGTATCCGTTCAAGCCTCCCATGATCAAATTCACAACCAAGATCTACCACCCCAA
  CGTGGACGAGAACGGACAGATTTGCCTGCCCATCATCAGCAGTGAGAACTGGAAGCCTTG
  CACCAAGACTTGCCAAGTCCTGGAGGCCCTCAATGTGCTGGTGAATAGACCGAATATCAG
  GGAGCCCCTGCGGATGGACCTCGCTGACCTGCTGACACAGAATCCGGAGCTGTTCAGAAA
  GAATGCCGAAGAGTTCACCCTCCGATTCGGAGTGGACCGGCCCTCCTAACTCATGTTCTG
  ACCCTCTGTGCACTGGATCCTCGGCATAGCGGACGGACACACCTCATGGACTGAGGCCAG
  AGCCCCCTGTGGCCCATTCCCCATTCATTTTTCCCTTCTTAAGTTGNTAGTCATTANTTT
  GTGTGTGTGTGTGGTGGAGGGAAGGGAGCTATGAGTGTGTGTGTTGTGTATGGACTCACT
  CCCAGGTTCACCTGGCCACAGGTGCACCCCTTCCCACACCCTTTACATTCCCCAGAGCCA
  AGGGAGTTTAAGTTTGCAGNTACAGGCCAGTTCTTCAGCTCTCCATCTTANAGAGACAGT
  CACCTTGCAGCCCTGCTTGGCAGAAATGAACCAAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_198183
• ORF Size: 264 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_198183.1, NP_937826.1
• RefSeq Size: 1269
• RefSeq ORF: 264
• Locus ID: 9246
• Protein Pathways: Parkinson's disease, Ubiquitin mediated proteolysis
• Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011]
  Transcript Variant: This variant (2) contains an alternate 5' exon and uses a downstream start codon, as compared to variant 1. The encoded isoform (2) is thus shorter when it is compared to isoform 1.