KTEL1 (POGLUT1) (NM_152305) Human Untagged Clone

CAT#: SC127242

POGLUT1 (untagged)-Human protein O-glucosyltransferase 1 (POGLUT1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: POGLUT1
• Synonyms: C3orf9; CLP46; hCLP46; KDELCL1; KTELC1; LGMD2Z; LGMDR21; MDS010; MDSRP; Rumi
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_152305, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGTGGTGGGCTAGCTCGCCGCTTCGGCTCTGGCTGCTGTTGTTCCTCCTGCCCTCAGCGCAGGGCC
  GCCAGAAGGAGTCAGGTTCAAAATGGAAAGTATTTATTGACCAAATTAACAGGTCTTTGGAGAATTACGA
  ACCATGTTCAAGTCAAAACTGCAGCTGCTACCATGGTGTCATAGAAGAGGATCTAACTCCTTTCCGAGGA
  GGCATCTCCAGGAAGATGATGGCAGAGGTAGTCAGACGGAAGCTAGGGACCCACTATCAGATCACTAAGA
  ACAGACTGTACCGGGAAAATGACTGCATGTTCCCCTCAAGGTGTAGTGGTGTTGAGCACTTTATTTTGGA
  AGTGATCGGGCGTCTCCCTGACATGGAGATGGTGATCAATGTACGAGATTATCCTCAGGTTCCTAAATGG
  ATGGAGCCTGCCATCCCAGTCTTCTCCTTCAGTAAGACATCAGAGTACCATGATATCATGTATCCTGCTT
  GGACATTTTGGGAAGGGGGACCTGCTGTTTGGCCAATTTATCCTACAGGTCTTGGACGGTGGGACCTCTT
  CAGAGAAGATCTGGTAAGGTCAGCAGCACAGTGGCCATGGAAAAAGAAAAACTCTACAGCATATTTCCGA
  GGATCAAGGACAAGTCCAGAACGAGATCCTCTCATTCTTCTGTCTCGGAAAAACCCAAAACTTGTTGATG
  CAGAATACACCAAAAACCAGGCCTGGAAATCTATGAAAGATACCTTAGGAAAGCCAGCTGCTAAGGATGT
  CCATCTTGTGGATCACTGCAAATACAAGTATCTGTTTAATTTTCGAGGCGTAGCTGCAAGTTTCCGGTTT
  AAACACCTCTTCCTGTGTGGCTCACTTGTTTTCCATGTTGGTGATGAGTGGCTAGAATTCTTCTATCCAC
  AGCTGAAGCCATGGGTTCACTATATCCCAGTCAAAACAGATCTCTCCAATGTCCAAGAGCTGTTACAATT
  TGTAAAAGCAAATGATGATGTAGCTCAAGAGATTGCTGAAAGGGGAAGCCAGTTTATTAGGAACCATTTG
  CAGATGGATGACATCACCTGTTACTGGGAGAACCTCTTGAGTGAATACTCTAAATTCCTGTCTTATAATG
  TAACGAGAAGGAAAGGTTATGATCAAATTATTCCCAAAATGTTGAAAACTGAACTATAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152305 unedited
  TTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGCAGTAGGTCT
  GCCGGCGATGGAGTGGTGGGCTAGCTCGCCGCTTCGGCTCTGGCTGCTGTTGTTCCTCCT
  GCCCTCAGCGCAGGGCCGCCAGAAGGAGTCAGGTTCAAAATGGAAAGTATTTATTGACCA
  AATTAACAGGTCTTTGGAGAATTACGAACCATGTTCAAGTCAAAACTGCAGCTGCTACCA
  TGGTGTCATAGAAGAGGATCTAACTCCTTTCCGAGGAGGCATCTCCAGGAAGATGATGGC
  AGAGGTAGTCAGACGGAAGCTAGGGACCCACTATCAGATCACTAAGAACAGACTGTACCG
  GGAAAATGACTGCATGTTCCCCTCAAGGTGTAGTGGTGTTGAGCACTTTATTTTGGAAGT
  GATCGGGCGTCTCCCTGACATGGAGATGGTGATCAATGTACGAGATTATCCTCAGGTTCC
  TAAATGGATGGAGCCTGCCATCCCAGTCTTCTCCTTCAGTAAGACATCAGAGTACCATGA
  TATCATGTATCCTGCTTGGACATTTTGGGAAGGGGGACCTGCTGTTTGGCCAATTTATCC
  TACAGGTCTTGGACGGTGGGACCTCTTCAGAGAGATCTGGTAGGTCAGCAGCACAGTGGC
  CATGGAANAAGAAAAACTCTACAGCATATTTCCGAGGATCAAGGGACAGTCCAGAACGAG
  ATCCTCTCATTCTTCTGTCTNCGAAAAACCCAAACTTGTTGATGCAGAATACACCAAAAC
  CAGGCCTGGNAATCTATGAAGATCCTTTAGAAGCCAGCTGCTAAGATGTCATCTTGTGGA
  TACTGCAATACAGTATCTGTTATTNTCGAGCGTACTGCAGTTNCCGGTTAACACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_152305 unedited
  GACCGAGGCCCGCCTCTAGNATCGAGTTTTTTTTTTTTTTTTTTAGCTTTAGAGAGGCAT
  TAAGAAGTAGGGCACTGAAGGCACCAAAAAGGGGAACCTCGAAATCCAATTGCAATAATT
  ACTCATGCAATTGGCCTCTTTCTATGTGGCATTATAGAAACCTCCTGAGTAACAGAGTTT
  ATGGTTTTACAAAAGAGAACTCCTACATCATTGCATGGCATGGCTACCGCTTCCTTAGAC
  CATTCAGAGAATGATCCCCAAGTATTTTTCATAAACCCCATAGGGTTTCCTACATTAAAA
  TAAAGTGACAGAGATCACGCCTTGAATAATTTCACAATTCCAGCAATGAGTTGTACTACT
  TCCAAATGACGAATTTTCTGCTCCAAATAATGGGACAAAGGGCATCATCACATGGACACA
  GTCAATTTCACAGTGATGGACTCACACAGGTGGATGATCTGAGGCACAAGCTGTGATTGG
  TCTTAAGAAAATGAAAGGTAGAGTTGGGTTCAAAATCCACATCTCACGATTTCTGGTCCT
  TATTCATCCAAAAAGTTGAACTGCTTCATATCAGTGTATTAGACACATTTTAAATCTTTC
  TCAAGAGTTGCTCTGGGTGCAGCATGATAAGGAAAACCAGGTATTTGGCTTGATAGCAGA
  TATTCAAGGTATAGGTGCCAAGCTTATGGGAAGCTTCTCACCGTAAGATATCTGAGATCT
  CGTGCCACAAAGAGGACTATGGGCCTATGATGACTACTATAGTTCAGTTTTCAACCATTT
  TGGGATTAATTTGATCCTAACCTTTCCTTCTCGTTCACTAATAGACCGGAATTTAGAGTA
  TTCCTCCAGAGGTTCTCCCACAACAGGTGGTGTTACTCCATCTGCAAGGTCCCTAAAAAC
  TGGTTTCCCTTTACCAACTCTGAGCTTCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_152305
• ORF Size: 1179 bp
• Insert Size: 1960
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_152305.1, NP_689518.1
• RefSeq Size: 3538
• RefSeq ORF: 1179
• Locus ID: 56983
• Gene Summary: This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
  Transcript Variant: This variant (1) represents the shorter transcript and is protein coding.