Histone acetyltransferase MYST3 (KAT6A) (NM_006766) Human Untagged Clone

CAT#: SC127275

KAT6A (untagged)-Human MYST histone acetyltransferase (monocytic leukemia) 3 (MYST3), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KAT6A
• Synonyms: MOZ; MRD32; MYST-3; MYST3; RUNXBP2; ZC2HC6A; ZNF220
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_006766 edited
  ATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGATTTTGGAGGCCATCAAAAAAGTG
  AAAAAGCAGAAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCAT
  GGCTTGGATCGTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATT
  TTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGATCCTGATAATCCTGGGCGAATA
  GCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATAAACAAAATGTGGATTGGAAT
  AAACTGATAAAGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGC
  ATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGCATTATTCGGAGGCAGTGCTGCC
  TCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTC
  CTTAAAGATGGACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAG
  AGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCTTCTTCCACATGAAAAGGATAAG
  CCGGTTGCTGAACCAATCCCCATCTGTAGTTTCTGTCTTGGTACAAAAGAACAAAACCGA
  GAAAAGAAGCCAGAGGAACTCATCTCCTGTGCCGACTGTGGCAACAGTGGCCATCCATCC
  TGTTTAAAGTTTTCCCCTGAACTAACGGTTCGAGTGAAGGCCTTACGGTGGCAGTGCATC
  GAGTGTAAAACATGCAGCTCCTGTCGAGATCAAGGCAAAAATGCGGATAACATGCTCTTT
  TGTGATTCATGTGACCGAGGTTTTCACATGGAGTGTTGTGATCCGCCACTCACCCGTATG
  CCAAAAGGCATGTGGATATGTCAAATATGTCGACCTAGGAAAAAAGGACGAAAACTTCTA
  CAAAAGAAGGCAGCACAGATAAAACGGCGCTATACTAATCCAATAGGACGTCCAAAAAAC
  AGGTTAAAGAAACAAAACACGGTATCAAAAGGTCCCTTCAGCAAAGTTCGAACTGGCCCT
  GGAAGGGGTAGGAAACGAAAAATCACTCTTTCCAGCCAATCAGCATCATCATCATCAGAA
  GAAGGATATTTAGAGCGGATAGATGGCTTGGACTTCTGCAGAGATAGCAATGTCTCCTTG
  AAGTTCAACAAGAAAACCAAAGGGCTCATTGATGGCCTTACCAAATTTTTTACCCCTTCC
  CCTGATGGGCGGAAAGCTCGGGGGGAAGTGGTGGACTACTCTGAGCAATATCGAATCAGA
  AAGAGGGGCAACAGGAAATCAAGCACTTCAGATTGGCCCACAGACAATCAGGATGGCTGG
  GATGGCAAACAAGAAAATGAGGAGCGACTTTTTGGGAGCCAGGAAATCATGACTGAGAAA
  GATATGGAATTATTTCGTGATATCCAAGAACAAGCACTGCAGAAAGTTGGAGTGACTGGT
  CCCCCTGATCCACAAGTCCGCTGTCCCTCTGTCATTGAGTTTGGGAAGTATGAAATTCAC
  ACCTGGTACTCCTCCCCATATCCTCAAGAATACTCAAGGCTGCCCAAATTGTATCTTTGT
  GAATTTTGTCTAAAATATATGAAAAGTAGAACTATTCTGCAGCAGCACATGAAGAAATGT
  GGTTGGTTCCATCCTCCTGCCAATGAGATTTACAGAAAGAATAATATTTCTGTCTTTGAG
  GTTGATGGGAATGTGAGTACCATTTATTGTCAAAACCTGTGTCTTTTGGCAAAGTTGTTT
  CTTGACCACAAAACCCTCTATTACGATGTGGAGCCATTTCTTTTTTATGTACTAACACAG
  AATGATGTCAAGGGCTGCCACCTTGTTGGCTACTTTTCTAAGGAAAAGCACTGCCAACAG
  AAGTACAATGTTTCCTGTATAATGATTCTTCCTCAATACCAGCGTAAGGGCTATGGCAGG
  TTTCTCATCGATTTCAGTTATTTGTTATCAAAGCGTGAAGGCCAAGCAGGGTCTCCAGAG
  AAACCGTTATCTGATCTGGGTCGTCTTTCCTACATGGCATATTGGAAAAGTGTAATATTG
  GAGTGCCTTTATCACCAAAATGACAAGCAGATCAGCATTAAGAAGTTAAGCAAGTTGACT
  GGAATCTGCCCTCAAGACATCACTTCCACACTCCACCACCTACGAATGCTGGACTTCCGT
  AGTGACCAATTTGTGATTATCCGCCGGGAAAAACTTATCCAGGATCACATGGCAAAGCTT
  CAGCTGAATTTGCGACCTGTAGATGTAGATCCAGAATGTTTGCGCTGGACTCCAGTCATA
  GTGTCCAACTCTGTGGTCTCAGAGGAGGAAGAAGAGGAGGCTGAGGAAGGAGAAAACGAA
  GAGCCACAGTGCCAGGAAAGAGAATTAGAGATCAGTGTGGGAAAGTCTGTGTCTCATGAG
  AACAAAGAACAAGATTCTTATTCAGTAGAAAGTGAAAAGAAACCAGAAGTTATGGCTCCA
  GTCAGTTCTACACGTTTGAGCAAACAAGTCCTTCCTCATGATAGTCTTCCTGCAAATAGC
  CAGCCATCTCGGAGGGGCCGCTGGGGGAGGAAGAACAGAAAAACCCAGGAACGTTTTGGT
  GATAAAGATTCTAAACTGCTCTTGGAAGAGACGTCTTCAGCTCCTCAGGAACAATATGGA
  GAATGTGGGGAGAAATCAGAAGCCACCCAGGAACAATACACTGAAAGTGAAGAACAGCTG
  GTGGCTTCTGAGGAGCAGCCAAGCCAGGACGGGAAACCTGACCTTCCCAAGAGAAGACTC
  AGTGAGGGGGTTGAGCCCTGGCGAGGACAGCTCAAGAAAAGCCCTGAGGCTCTGAAGTGC
  AGATTAACAGAAGGAAGTGAGAGGCTGCCCCGTCGCTACAGTGAGGGTGACAGGGCTGTC
  CTCAGGGGCTTCAGTGAGAGCAGCGAGGAGGAGGAGGAGCCGGAAAGCCCTCGGTCAAGC
  TCGCCACCAATTCTCACAAAGCCCACGCTGAAGCGAAAGAAACCATTTCTCCACCGAAGG
  AGGAGAGTCCGAAAGCGCAAACACCACAATAGCAGTGTAGTCACAGAAACTATTTCTGAG
  ACCACTGAAGTGTTAGATGAACCTTTTGAAGATTCTGACTCCGAGAGGCCAATGCCAAGA
  TTAGAACCCACGTTTGAGATCGATGAAGAAGAGGAGGAAGAGGATGAAAATGAACTTTTC
  CCTAGAGAATACTTCCGTCGTTTGTCTTCGCAGGATGTACTCAGGTGTCAGTCCTCTTCT
  AAGAGGAAGTCTAAAGATGAAGAAGAAGATGAAGAGTCAGATGATGCTGATGACACTCCT
  ATCTTAAAGCCAGTATCTCTTTTGCGAAAACGTGATGTGAAGAATTCTCCTCTTGAGCCA
  GATACATCCACACCTTTGAAAAAGAAAAAGGGATGGCCCAAAGGCAAGAGCCGCAAACCA
  ATCCACTGGAAGAAAAGACCTGGTCGAAAACCAGGATTTAAGTTGAGTCGGGAAATCATG
  CCAGTTTCTACTCAAGCATGCGTCATTGAGCCCATCGTTTCCATTCCTAAAGCTGGACGT
  AAACCCAAGATCCAGGAGAGTGAAGAAACTGTTGAGCCAAAAGAAGACATGCCCCTACCC
  GAGGAGAGGAAGGAGGAGGAGGAGATGCAAGCAGAGGCAGAAGAGGCTGAAGAGGGTGAG
  GAAGAGGATGCAGCCAGCAGTGAAGTCCCAGCAGCCTCTCCAGCAGACAGCAGCAATAGT
  CCTGAGACCGAAACCAAGGAGCCTGAGGTGGAGGAGGAAGAAGAGAAGCCCCGTGTCTCA
  GAGGAGCAGAGGCAGTCAGAGGAGGAGCAGCAGGAATTAGAGGAGCCAGAGCCAGAGGAG
  GAGGAAGATGCAGCTGCAGAGACTGCCCAGAATGACGACCACGACGCTGATGATGAGGAT
  GATGGCCACCTGGAGTCCACAAAGAAAAAGGAGCTAGAGGAACAGCCCACGAGGGAAGAT
  GTCAAGGAGGAGCCTGGTGTTCAAGAGTCTTTTTTAGATGCTAATATGCAGAAGAGTAGG
  GAAAAGATAAAGGATAAAGAGGAAACCGAGCTGGATTCCGAAGAGGAGCAGCCTTCCCAT
  GACACGTCCGTGGTGTCAGAGCAGATGGCTGGGTCTGAGGACGACCACGAAGAAGACTCC
  CACACTAAGGAAGAGTTAATCGAATTAAAAGAGGAGGAAGAGATTCCTCATAGTGAGCTG
  GATCTGGAAACTGTACAGGCAGTGCAGTCTTTGACTCAAGAAGAAAGCAGTGAGCATGAG
  GGCGCCTACCAGGACTGTGAGGAAACTCTTGCGGCGTGTCAGACCCTGCAGAGTTACACC
  CAGGCTGACGAGGACCCTCAGATGTCCATGGTTGAAGACTGTCATGCGTCAGAACATAAT
  AGCCCTATCTCCTCCGTTCAGTCTCACCCCAGCCAGTCAGTCCGTTCGGTCAGCAGTCCC
  AACGTGCCTGCCCTTGAGAGTGGCTACACCCAGATCAGCCCAGAACAAGGATCCCTGTCC
  GCACCCTCTATGCAGAACATGGAGACCAGCCCCATGATGGATGTGCCTTCCGTATCAGAC
  CACTCTCAGCAGGTGGTGGACAGCGGCTTCAGTGACCTGGGCAGCATTGAGAGCACCACT
  GAAAACTATGAGAACCCAAGCAGTTACGACTCCACGATGGGCGGCAGCATCTGTGGGAAC
  AGCTCTTCCCAGAGCAGCTGCTCCTACGGTGGGCTGTCGTCCTCCAGCAGCCTCACCCAG
  AGCAGCTGTGTGGTCACTCAGCAGATGGCCAGCATGGGCAGCAGCTGCAGCATGATGCAG
  CAGAGCAGCGTCCAGCCTGCTGCCAACTGCAGCATCAAGTCACCTCAGAGCTGCGTGGTG
  GAGAGGCCTCCCAGTAACCAGCAGCAGCAGCCGCCACCACCGCCTCCACAGCAGCCACAG
  CCGCCGCCGCCACAACCACAACCAGCACCACAGCCTCCACCACCCCAGCAGCAGCCGCAA
  CAGCAGCCGCAGCCTCAGCCCCAGCAGCCTCCACCCCCACCCCCTCCCCAGCAGCAGCCC
  CCGCTGTCACAGTGTAGTATGAATAACAGTTTCACCCCAGCTCCTATGATCATGGAGATA
  CCAGAATCTGGAAGCACTGGGAACATAAGTATCTATGAGAGGATTCCAGGGGATTTTGGT
  GCCGGCAGCTACTCTCAACCATCAGCCACCTTCAGCCTAGCCAAGCTGCAGCAGCTGACC
  AACACCATTATGGACCCTCATGCCATGCCTTATAGCCATTCTCCTGCTGTGACTTCCTAT
  GCAACCAGTGTTTCTCTGTCCAATACAGGACTGGCTCAGCTGGCTCCATCTCATCCCTTA
  GCTGGGACTCCTCAAGCACAAGCCACCATGACGCCACCCCCAAACTTGGCATCCACTACC
  ATGAACCTCACATCTCCTCTGCTTCAGTGCAACATGTCTGCCACCAACATTGGCATTCCT
  CACACGCAGAGATTGCAAGGGCAAATGCCAGTGAAGGGGCACATTTCCATCCGCTCCAAG
  TCTGCGCCACTGCCCTCTGCGGCTGCTCACCAGCAGCAGCTGTATGGCCGTAGCCCATCG
  GCAGTTGCCATGCAGGCTGGCCCTCGCGCACTGGCTGTTCAGCGTGGCATGAACATGGGG
  GTTAATCTGATGCCTACTCCCGCCTATAATGTCAATTCCATGAATATGAACACCTTGAAT
  GCCATGAACAGCTATCGAATGACACAGCCCATGATGAACAGCAGTTACCATAGTAACCCT
  GCCTACATGAACCAGACAGCACAGTATCCTATGCAGATGCAGATGGGAATGATGGGGAGC
  CAGGCCTATACCCAGCAGCCTATGCAGCCTAACCCTCATGGGAACATGATGTACACAGGC
  CCCTCCCATCACAGCTACATGAACGCTGCTGGCGTGCCCAAGCAGTCACTCAACGGACCT
  TACATGAGAAGATGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006766 unedited
  TATTACCCCGCCCGTTGNCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG
  CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC
  GAATTCGGCACGAGGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCG
  GGATCTCGGCTGTCCTTCCTCCCGGCATAAGATGCACATTTTTCTGCTCTGGAGCCGGGA
  ATGAAATATTCTTGAGTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTGAGA
  AATTCATTGGGAAGTTGGAAGACATTTCAAACAACAGGTTGTTTTGGTTTCTATAGTACA
  ATTGGGGTGGCATTCTGTTTTGTGAACTGAGGAAGGACTTAGGCCAGAAAACTCATATGC
  TATTGTTAACTGGTTCCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTACTCA
  GCATCAGGATAAGGGATAACGACCTTATGGATATACAGAATCCTTCACCATGGTAAAACT
  CGCANACCCGCTNTATACTGAGTGGATTNTGGAGGCCATCAAAAAAGTGAAAAAGCTGAA
  ACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGATCG
  TANAACTGTTTTAGAAACATTGTGAGTGAGTGTTAAAGATGGGACAATTTTAAAGTCTCN
  AATAAGGACTCAATTCCTATAAGATCCTGGATATNCTGGGCGAATAGCACTTCCTAAGCC
  TCGGNACCATGGGANANNNTGGATATANACANATGTGGATTGGGATANACTGANTAAGCG
  GGCAGTTGAGGGCTTGGCAGACTCTGGTGGCTCCAACTTGAAAGCATTTGACGTTTTTTN
  GAGGGTCAGNAGGGATGTGTCTGCATTATTCGNAGGCAGGGCTTGCTCTGGCTTCACTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006766 unedited
  GGTTTTNNNNNNAAATACTGTGNNACCGCGGCCGCTTNCTANNGATCGATTTTTTTTTTT
  TTTTTTTACCTATCCCTGGNACAAGTAATAGGAAGAGAATGGGCAAACTGGTTGCACGAG
  AGAAAAGAGAATGGAGTTGGGAGCAACACATGAACTTGCGTTATAACATTCTGCTGTCCA
  GATCTGCCCTACTGTGCTGGTGGTCGGTCTGTCCCTCTTCTCATTAGCCACTCACAGGAG
  AGGTGCTTGTGCACTCTGATTCACAGGGGATGAACTCAGGATCTCAAAAGACATACAAAA
  ACTAGAGGTATGTATCACTTAAATAGCTACGAAACTCACACCGTGATCTCCCTTCTGACA
  CACATCTGCGCCATCTCTTCCAACATAAAATAAACTGTTTCAATGGTTTGTCAGTTATTT
  TTTAAATCACTAAAATGTACAGTCATCCACCACACATTTTAAGAAGAACCCCTAGAGCAN
  ATCACTGGGGACTGCTATTTGAGTTTTATCAGTCAAAAGCTCNAGCATNCAGACCCTCAG
  TTAGCATTTTCAAGTACATACTAGAAACCANNNAGCTGGTGGCNTGTGTGTGCCTTATTG
  CTGATTCACCAGGTGGTAAAAAACAAGAGGTTATCTCCTCTTTTTGATTGGTATTGACCA
  TCTCTATTCCTCAAAGCTGGATTGGATTGCAACAGCTTTCTCTGAGATCTGCTGTAATTG
  AGACTACAGATTTTTGTGTCTCTGATGCTGAGTGGAATTATTTAAAAAGAAGAAAAAATT
  TNTTACACTTGATTCAGAACACAAAGATTCATGAAGTCGTCTATAAGAACATTCTGGGAA
  AGGTTCAGAGTGTGTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006766
• ORF Size: 6015 bp
• Insert Size: 7900
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006766.2, NP_006757.1
• RefSeq Size: 7861
• RefSeq ORF: 6015
• Locus ID: 7994
• Domains: PHD, MOZ_SAS, linker_histone
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).