beta 1 Adrenergic Receptor (ADRB1) (NM_000684) Human Untagged Clone

CAT#: SC127880

ADRB1 (untagged)-Human adrenergic, beta-1-, receptor (ADRB1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADRB1
• Synonyms: ADRB1R; B1AR; BETA1AR; FNSS2; RHR
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000684 edited
  CTTCTGGGGTGTTCCCCAACCACGGCCCAGCCCTGCCACACCCCCCGCCCCCGGCCTCCG
  CAGCTCGGCATGGGCGCGGGGGTGCTTGTCCTGGGCGCCTCCGAGCCCGGTAACCTGTCG
  TCGGCCGCACCGCTCCCCGACGGCGCGGCCACCGCGGCGCGGCTGCTGGTGCCCGCGTCG
  CCGCCCGCCTCGTTGCTGCCTCCCGCCAGCGAAAGCCCCGAGCCGCTGTCTCAGCAGTGG
  ACAGCGGGCATGGGTCTGCTGATGGCGCTCATCGTGCTGCTCATCGTGGCGGGCAATGTG
  CTGGTGATCGTGGCCATCGCCAAGACGCCGCGGCTGCAGACGCTCACCAACCTCTTCATC
  ATGTCCCTGGCCAGCGCCGACCTGGTCATGGGGCTGCTGGTGGTGCCGTTCGGGGCCACC
  ATCGTGGTGTGGGGCCGCTGGGAGTACGGCTCCTTCTTCTGCGAGCTGTGGACCTCAGTG
  GACGTGCTGTGCGTGACGGCCAGCATCGAGACCCTGTGTGTCATTGCCCTGGACCGCTAC
  CTCGCCATCACCTCGCCCTTCCGCTACCAGAGCCTGCTGACGCGCGCGCGGGCGCGGGGC
  CTCGTGTGCACCGTGTGGGCCATCTCGGCCCTGGTGTCCTTCCTGCCCATCCTCATGCAC
  TGGTGGCGGGCGGAGAGCGACGAGGCGCGCCGCTGCTACAACGACCCCAAGTGCTGCGAC
  TTCGTCACCAACCGGGCCTACGCCATCGCCTCGTCCGTAGTCTCCTTCTACGTGCCCCTG
  TGCATCATGGCCTTCGTGTACCTGCGGGTGTTCCGCGAGGCCCAGAAGCAGGTGAAGAAG
  ATCGACAGCTGCGAGCGCCGTTTCCTCGGCGGCCCAGCGCGGCCGCCCTCGCCCTCGCCC
  TCGCCCGTCCCCGCGCCCGCGCCGCCGCCCGGACCCCCGCGCCCCGCCGCCGCCGCCGCC
  ACCGCCCCGCTGGCCAACGGGCGTGCGGGTAAGCGGCGGCCCTCGCGCCTCGTGGCCCTG
  CGCGAGCAGAAGGCGCTCAAGACGCTGGGCATCATCATGGGCGTCTTCACGCTCTGCTGG
  CTGCCCTTCTTCCTGGCCAACGTGGTGAAGGCCTTCCACCGCGAGCTGGTGCCCGACCGC
  CTCTTCGTCTTCTTCAACTGGCTGGGCTACGCCAACTCGGCCTTCAACCCCATCATCTAC
  TGCCGCAGCCCCGACTTCCGCAAGGCCTTCCAGGGACTGCTCTGCTGCGCGCGCAGGGCT
  GCCCGCCGGCGCCACGCGACCCACGGAGACCGGCCGCGCGCCTCGGGCTGTCTGGCCCGG
  CCCGGACCCCCGCCATCGCCCGGGGCCGCCTCGGACGACGACGACGACGATGTCGTCGGG
  GCCACGCCGCCCGCGCGCCTGCTGGAGCCCTGGGCCGGCTGCAACGGCGGGGCGGCGGCG
  GACAGCGACTCGAGCCTGGACGAGCCGTGCCGCCCCGGCTTCGCCTCGGAATCCAAGGTG
  TAGGGCCCGGCGCGGGGCGCGGACTCCGGGCACGGCTTCCCAGGGGAACGAGGAGATCTG
  TGTTTACTTAAGACCGATAGCAGGTGAACTCGAAGCCCACAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000684 unedited
  ATAGGGCGGCCGCGAATTCGCCCTTCTGGGGTGTTCCCCAACCACGGCGNANCGCCGTAA
  CACCCCCCGCCCCCGGCCTCCGCAGCTCGGCATGGGCGCGGGGGTGCTTGTCCTGGGCGC
  CTCCGAGCCCGGTAACCTGTCGTCGGCCGCACCGCTCCCCGACGGCGCGGCCACCGCGGC
  GCGGCTGCTGGTGCCCGCGTCGCCGCCCGCCTCGTTGCTGCCTCCCGCCAGCGAAAGCCC
  CGAGCCGCTGTCTCAGCAGTGGACAGCGGGCATGGGTCTGCTGATGGCGCTCATCGTGCT
  GCTTATCGTGGCGGGCAATGTGCTGGTGATCGTGGCCCATCGCCAAGACGCCGCGGCTGG
  AGACGCTTAACAACCTTTTCATCATGTCCCTGGCCAGCGGCCACCTGGATAAGGGGCTAG
  TGGTGGTTGCCGTTCGGGGCAACATTCCGGTGTGGGGCCCACTGGGAAATCAGGTCCCTT
  TCTTTGCGAGCTTGGGACCTTAATGGAATTGCTTGTCGTGAAGGCCAGCCCCTCAACCCC
  GGGGGGTCTATGCCTGGACCATATATCTGGAACTAATTTGCGATTTTGCATCTAAAACAC
  GATAACTCCCCCCGGGGCACGGAGATCTCTTTGGTCCCAGTGTGGTCACACTACGGCTCT
  CGGATTCCTTCCTAACCATTTCACTAAGCCGTGGGGCAGGAGAATTAAGAAATAGCTGCA
  CGCTTGCTAAAGATCCCTGAAAGGTGGAGATGTGTCAATACTTGGTAACAT
  
• Restriction Sites: Please inquire
• ACCN: NM_000684
• Insert Size: 1600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000684.1, NP_000675.1
• RefSeq Size: 1723 bp
• RefSeq ORF: 1434 bp
• Locus ID: 153
• Cytogenetics: 10q25.3
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Dilated cardiomyopathy, Endocytosis, Gap junction, Neuroactive ligand-receptor interaction
• Gene Summary: 'The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Sep 2019]'