PTPRS (NM_130853) Human Untagged Clone

CAT#: SC128017

PTPRS (untagged)-Human protein tyrosine phosphatase, receptor type, S (PTPRS), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRS
• Synonyms: PTPSIGMA; R-PTP-S; R-PTP-sigma
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_130853, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTGGTCCCATGGGCCTCCTTGTGGTCCTGCTCG
  TTGGAGGCTGTGCAGCAGAAGAGCCCCCCAGGTTTATCAAAGAACCCAAGGACCAGATCGGCGTGTCGGG
  GGGTGTGGCCTCTTTCGTGTGTCAGGCCACGGGTGACCCCAAGCCACGAGTGACCTGGAACAAGAAGGGC
  AAGAAGGTCAACTCTCAGCGCTTTGAGACGATTGAGTTTGATGAGAGTGCAGGGGCAGTGCTGAGGATCC
  AGCCGCTGAGGACACCGCGGGATGAAAACGTGTACGAGTGTGTGGCCCAGAACTCGGTTGGGGAGATCAC
  AGTCCATGCCAAGCTTACTGTCCTCCGAGAGGACCAGCTGCCCTCTGGCTTCCCCAACATCGACATGGGC
  CCACAGTTGAAGGTGGTGGAGCGGACACGGACAGCCACCATGCTCTGTGCAGCCAGCGGCAACCCTGACC
  CTGAGATCACCTGGTTCAAGGACTTCCTGCCTGTGGATCCTAGTGCCAGCAATGGACGCATCAAACAGCT
  GCGATCAGGAGCCCTGCAGATTGAAAGCAGTGAGGAAACCGACCAGGGCAAATATGAGTGTGTGGCCACC
  AACAGCGCCGGCGTGCGCTACTCCTCACCTGCCAACCTCTACGTGCGAGTCCGCCGCGTGGCCCCGCGCT
  TCTCCATCCTGCCCATGAGCCACGAGATCATGCCAGGGGGCAACGTGAACATCACCTGCGTGGCCGTGGG
  CTCGCCCATGCCATACGTGAAGTGGATGCAGGGGGCCGAGGACCTGACCCCCGAGGATGACATGCCCGTG
  GGTCGGAACGTGCTGGAACTCACAGATGTCAAGGACTCGGCCAACTACACCTGCGTGGCCATGTCCAGCC
  TGGGCGTCATTGAGGCGGTTGCTCAGATCACGGTGAAATCTCTCCCCAAAGCTCCCGGGACTCCCATGGT
  GACTGAGAACACAGCCACCAGCATCACCATCACGTGGGACTCGGGCAACCCAGATCCTGTGTCCTATTAC
  GTCATCGAATATAAATCCAAGAGCCAAGACGGGCCGTATCAGATTAAAGAGGACATCACCACCACACGTT
  ACAGCATCGGCGGCCTGAGCCCCAACTCGGAGTACGAGATCTGGGTGTCGGCCGTCAACTCCATCGGCCA
  GGGGCCCCCCAGCGAGTCCGTGGTCACCCGCACAGGCGAGCAGGCCCCGGCCAGCGCGCCGCGGAACGTG
  CAAGCCCGGATGCTCAGCGCGACCACCATGATTGTGCAGTGGGAGGAGCCGGTGGAGCCCAACGGCCTGA
  TCCGCGGCTACCGCGTCTACTACACCATGGAACCGGAGCACCCCGTGGGCAACTGGCAGAAGCACAACGT
  GGACGACAGCCTGCTGACCACCGTGGGCAGCCTGCTGGAGGACGAGACCTACACCGTGCGGGTGCTCGCC
  TTCACCTCCGTCGGCGACGGGCCCCTCTCGGACCCCATCCAGGTCAAGACGCAGCAGGGAGTGCCGGGCC
  AGCCCATGAACCTGCGGGCCGAGGCCAGGTCGGAGACCAGCATCACGCTGTCCTGGAGCCCCCCGCGGCA
  GGAGAGTATCATCAAGTACGAGCTCCTCTTCCGGGAAGGCGACCATGGCCGGGAGGTGGGAAGGACCTTC
  GACCCGACGACTTCCTACGTGGTGGAGGACCTGAAGCCCAACACGGAGTACGCCTTCCGCCTGGCGGCCC
  GCTCGCCGCAGGGCCTGGGCGCCTTCACCCCCGTGGTGCGGCAGCGCACGCTGCAGTCCATCTCGCCCAA
  GAACTTCAAGGTGAAAATGATCATGAAGACATCAGTTCTGCTCAGCTGGGAGTTCCCTGACAACTACAAC
  TCACCCACACCCTACAAGATCCAGTACAATGGGCTCACACTGGATGTGGATGGCCGTACCACCAAGAAGC
  TCATCACGCACCTCAAGCCCCACACCTTCTACAACTTTGTGCTGACCAATCGCGGCAGCAGCCTGGGCGG
  CCTCCAGCAGACGGTCACCGCCTGGACTGCCTTCAACCTGCTCAACGGCAAGCCCAGCGTCGCCCCCAAG
  CCTGATGCTGACGGCTTCATCATGGTGTATCTTCCTGACGGCCAGAGCCCCGTGCCTGTCCAGAGCTATT
  TCATTGTGATGGTGCCACTGCGCAAGTCTCGTGGAGGCCAATTCCTGACCCCGCTGGGTAGCCCAGAGGA
  CATGGATCTGGAAGAGCTCATCCAGGACATCTCACGGCTACAGAGGCGCAGCCTGCGGCACTCGCGTCAG
  CTGGAGGTGCCCCGGCCCTATATTGCAGCTCGCTTCTCTGTGCTGCCACCCACGTTCCATCCCGGCGACC
  AGAAGCAGTATGGCGGCTTCGATAACCGGGGCCTGGAGCCCGGCCACCGCTATGTCCTCTTCGTGCTTGC
  CGTGCTTCAGAAGAGCGAGCCTACCTTTGCAGCCAGTCCCTTCTCAGACCCCTTCCAGCTGGATAACCCG
  GACCCCCAGCCCATCGTGGATGGCGAGGAGGGGCTTATCTGGGTGATCGGGCCTGTGCTGGCCGTGGTCT
  TCATAATCTGCATTGTCATTGCTATCCTGCTCTACAAGAACAAACCCGACAGTAAACGCAAGGACTCAGA
  ACCCCGCACCAAATGCCTCCTGAACAATGCCGACCTCGCCCCTCACCACCCCAAGGACCCTGTGGAAATG
  AGACGCATTAACTTCCAGACTCCAGGCATGCTTAGCCACCCGCCAATTCCCATCGCAGACATGGCGGAGC
  ACACGGAGCGGCTCAAGGCCAACGACAGCCTCAAGCTCTCCCAGGAGTATGAGTCCATCGACCCTGGACA
  GCAGTTCACATGGGAACATTCCAACCTGGAAGTGAACAAGCCGAAGAACCGCTATGCCAACGTCATCGCC
  TATGACCACTCCCGTGTCATCCTCCAGCCCATTGAAGGCATCATGGGCAGTGATTACATCAATGCCAACT
  ACGTGGACGGCTACCGGTGTCAGAACGCGTACATTGCCACGCAGGGGCCGCTGCCTGAGACCTTTGGGGA
  CTTCTGGCGTATGGTGTGGGAGCAGCGGTCGGCGACCATCGTCATGATGACGCGGCTGGAGGAGAAGTCA
  CGGATCAAGTGTGATCAGTATTGGCCCAACAGAGGCACGGAGACCTACGGCTTCATCCAGGTCACGTTGC
  TAGATACCATCGAGCTGGCCACATTCTGCGTCAGGACATTCTCTCTGCACAAGAATGGCTCCAGTGAGAA
  ACGCGAGGTCCGCCAGTTCCAGTTTACGGCGTGGCCGGACCATGGCGTGCCCGAATACCCAACGCCCTTC
  CTGGCTTTCCTGCGGAGAGTCAAGACCTGCAACCCGCCAGATGCCGGCCCCATCGTGGTTCACTGCAGTG
  CCGGTGTGGGCCGCACAGGCTGCTTTATCGTCATCGACGCCATGCTTGAGCGGATCAAGCCAGAGAAGAC
  AGTCGATGTCTATGGCCACGTGACGCTCATGAGGTCCCAGCGCAACTACATGGTGCAGACGGAGGACCAG
  TACAGCTTCATCCACGAGGCCCTGCTGGAGGCCGTGGGCTGTGGCAACACAGAAGTGCCCGCACGCAGCC
  TCTATGCCTACATCCAGAAGCTGGCCCAGGTGGAGCCTGGCGAACACGTCACTGGCATGGAACTCGAGTT
  CAAGCGGCTGGCTAACTCCAAGGCCCACACGTCACGCTTCATCAGTGCCAATCTGCCTTGTAACAAGTTC
  AAGAACCGCCTGGTGAACATCATGCCCTATGAGAGCACACGGGTCTGTCTGCAACCCATCCGGGGTGTGG
  AGGGCTCTGACTACATCAACGCCAGCTTCATTGATGGCTACAGGCAGCAGAAGGCCTACATCGCGACACA
  GGGGCCGCTGGCGGAGACCACGGAAGACTTCTGGCGCATGCTGTGGGAGAACAATTCGACGATCGTGGTG
  ATGCTGACCAAGCTGCGGGAGATGGGCCGGGAGAAGTGTCACCAGTACTGGCCGGCCGAGCGCTCTGCCC
  GCTACCAGTACTTTGTGGTAGATCCGATGGCAGAATACAACATGCCTCAGTATATCCTGCGAGAGTTCAA
  GGTCACAGATGCCCGGGATGGCCAGTCCCGGACTGTCCGGCAGTTCCAGTTCACAGACTGGCCGGAACAG
  GGTGTGCCAAAGTCGGGGGAGGGCTTCATCGACTTCATTGGCCAAGTGCATAAGACTAAGGAGCAGTTTG
  GCCAGGACGGCCCCATCTCTGTCCACTGCAGTGCCGGCGTGGGCAGGACGGGCGTCTTCATCACGCTTAG
  CATCGTGCTGGAGCGGATGCGGTATGAAGGCGTGGTGGACATCTTTCAGACGGTGAAGATGCTACGAACC
  CAGCGGCCGGCCATGGTGCAGACAGAGGATGAGTACCAGTTCTGTTACCAGGCGGCACTGGAGTACCTCG
  GAAGCTTTGACCACTATGCAACCTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_130853 unedited
  GGGGTGTCGGATATTTGTATACGACTTATATAGGCGGCCGCGCAATTCGCACGAGGCGCA
  CGCCGCGAGCCGCTGGCGCTCGGGCTCCGCTCGGATCCCATGCAACAGCCACGATGTGAA
  GCGGGGCAGAGCCGGGGGAGCCCAGCCCAGCCAGCCTCCAGACGTTGCCCCATCTGACGC
  TCGGCTCGAGGCCTCTCTGTGAGGGACCGGGGGGCCATCCCCCTCCAGGGCGGAGATCGG
  AGGTCGCTGCCAAGCATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTGGTCCC
  ATGGGCCTCCTTGTGGTCCTGCTCGTTGGAGGCTGTGCAGCAGAAGAGCCCCCCAGGTTT
  ATCAAAGAACCCAAGGACCAGATCGGCGTGTCGGGGGGTGTGGCCTCTTTCGTGTGTCAG
  GCCACGGGTGACCCCAAGCCACGAGTGACCTGGAACAAGAAGGGCAAGAAGGTCAACTCT
  CAGCGCTTTGAGACGATTGAGTTTGATGAGAGTGCAGGGGCAGTGCTGAGGATCCAGCCG
  CTGAGGACACCGCGGGATGAAAACGTGTACGAGTGTGTGGCCACGNACTCGGTTGGGGAG
  ATCACAGTCCATGCCAAGCTTACTGTCCTCCGAGAGGACCAGCTGCCCTCTGGCTTCCCC
  AACATCGACATGGGCCCACAGTTGAAGGTGGTGGAGCGGACACGGACAGCCACCATGCTC
  TGTGCAGCCAGCGGCAACCCTGACCCTGAGATCACCTGGTTCAAGGACTTCCTGCCTGTG
  GATCCTAGTGCCAGCAATGGACGCATCANACAGCTGCGATCAGGAGCCCTGCAGATTGAA
  AGCAGTGAGGAAACCGACCAGGGCAAATATGAGTGTGTGGCCACCAACAGCGCCG
  
  3' Read Nucleotide Sequence

  >Forward primer walk for NM_130853 unedited
  GNAGGGCCTACATCGCGNACACAGGGGCCGCTGNGCGGAAACCACGGAAGACTTCTGGCG
  CATGCTGTGGGAGAACAATTCGACGATCGTGGTGATGCTGACCAAGCTGCGGGAGATGGG
  CCGGGAGAAGTGTCACCAGTACTGGCCGGCCGAGCGCTCTGCCCGCTACCAGTACTTTGT
  GGTAGATCCGATGGCAGAATACAACATGCCTCAGTATATCCTGCGAGAGTTCAAGGTCAC
  AGATGCCCGGGATGGCCAGTCCCGGACTGTCCGGCAGTTCCAGTTCACAGACTGGCCGGA
  ACAGGGTGTGCCAAAGTCGGGGGAGGGCTTCATCGACTTCATTGGCCAAGTGCATAAGAC
  TAAGGAGCAGTTTGGCCAGGACGGCCCCATCTCTGTCCACTGCAGTGCCGGCGTGGGCAG
  GACGGGCGTCTTCATCACGCTTAGCATCGTGCTGGAGCGGATGCGGTATGAAGGCGTGGT
  GGACATCTTTCAGACGGTGAAGATGCTACGAACCCAGCGGCCGGCCATGGTGCAGACAGA
  GGATGAGTACCAGTTCTGTTACCAGGCGGCACTGGAGTACCTCGGAAGCTTTGACCACTA
  TGCAACCTAAAGCCATGGTCCCCCCCAGGCCCGACACCACTGGCCCCGGATGCCTCTGCC
  CCTCCCGGGCGGACCTCCTGAGGCCTGGACCCCCAGTGGGCAGGGCAGGAGGTGGCAGCG
  GCAGCAGCTGTGTTTCTGCACCATTTCCGAGGACGACGCAGCCCCTCGAGCCCCCCACCG
  GCCCCGGCCGCCCCAGCGACCTCCCTGGCACCGGCCGCCGCCTTCAATACTTGGCACATA
  TCTCCTTTCTCTTACAATTCCAA
  
• Restriction Sites: Please inquire
• ACCN: NM_130853
• ORF Size: 4506 bp
• Insert Size: 6000
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_130853.1, NP_570923.1
• RefSeq Size: 5159
• RefSeq ORF: 4506
• Locus ID: 5802
• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) lacks four internal fragments within the coding region when compared to variant 1. The translation remains in-frame, and thus results in a protein that lacks four internal segments, as compared to isoform 1. Sequence Note: The transcript 3'UTR sequence was derived from a genomic record (AC118535.1) based on a series of overlapping EST alignments.