Cullin 4B (CUL4B) (NM_003588) Human Untagged Clone

CAT#: SC128242

CUL4B (untagged)-Human cullin 4B (CUL4B), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CUL4B
• Synonyms: CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003588 edited
  AGTTCAGTTTAGAAACTGCCAGTCTTGGTATAGAACAACCTAGGCTTATCTGTTTAAGTC
  CCATAGGTAGTATTATTAGAGAATAACCCAGGCTTTGGGAACTGTATAACTCTGAGATCG
  TTTGAAATTTTCGTTTTGTTTTTCTTTTGGCTCCAACCAGGCCTCTGTTGTTAGACTAAT
  GGGGTTTCCCCTGCAGAGATTGGTCAGCCCTGCAGTCTATCATCCCGGAAGGTGTTAAAT
  ACACATGAAAGCCAGCCTCGGCGGGCAGAACCTAGCCCGCCGAAAGGGCGGGCATTGCTA
  AAGTGTTTTCAAAAGGTCTTCCCAATCCTCTGCTTTAGACAGCTCGGACCTTAGATAGAA
  GAACACAACGGATCCTCCAGTGACTGACGACCCAAAGGACGGATGATGTCACAGTCATCT
  GGATCAGGAGATGGGAATGATGATGAGGCTACTACCTCTAAAGACGGTGGTTTTTCTTCC
  CCCAGTCCCTCAGCTGCTGCTGCTGCTCAGGAGGTCAGATCTGCCACTGATGGTAATACC
  AGCACCACTCCGCCCACCTCTGCCAAGAAGAGAAAGTTAAACAGCAGCAGCAGTAGCAGC
  AGTAACAGTAGTAACGAGAGAGAAGACTTTGATTCCACCTCTTCCTCCTCTTCCACTCCT
  CCTTTACAACCCAGGGATTCGGCATCCCCTTCAACCTCGTCCTTCTGCCTGGGGGTTTCA
  GTGGCTGCTTCCAGCCACGTACCGATACAGAAGAAGCTGCGTTTTGAAGACACCCTGGAG
  TTTGTAGGGTTTGATGCGAAGATGGCTGAGGAATCCTCCTCCTCCTCCTCCTCATCTTCA
  CCAACTGCTGCAACATCTCAGCAGCAGCAACTTAAAAATAAGAGTATATTAATCTCTTCT
  GTGGCTTCGGTGCATCATGCAAACGGCCTAGCCAAATCTTCTACCACCGTCTCTAGCTTT
  GCTAACAGCAAACCTGGCTCTGCTAAGAAGTTAGTGATCAAGAACTTTAAAGATAAGCCT
  AAATTACCAGAAAACTACACAGATGAAACCTGGCAAAAACTGAAAGAAGCAGTGGAAGCT
  ATTCAGAATAGTACTTCAATTAAGTACAATTTAGAAGAACTCTACCAGGCTGTAGAAAAT
  CTCTGTTCTTACAAGATTTCTGCAAACTTGTACAAACAGCTGAGACAGATCTGCGAAGAT
  CACATCAAAGCACAGATTCATCAATTCAGAGAGGATTCATTGGATAGCGTTCTTTTTTTA
  AAGAAGATTGATAGATGCTGGCAAAACCATTGCAGACAAATGATCATGATCAGGAGCATT
  TTTTTGTTTCTGGATAGAACTTACGTTCTTCAGAATTCAATGCTACCCTCCATTTGGGAC
  ATGGGACTGGAGTTATTTAGGGCTCATATTATAAGTGATCAGAAAGTGCAGAATAAGACA
  ATTGATGGCATTCTTCTCTTGATTGAGAGGGAAAGGAATGGTGAAGCAATTGATAGAAGT
  TTACTTCGAAGCCTTTTAAGCATGCTGTCTGATTTGCAAATTTATCAAGATTCTTTTGAA
  CAACGATTTTTGGAAGAAACTAACCGGCTCTATGCAGCTGAAGGCCAAAAATTAATGCAA
  GAAAGAGAGGTTCCTGAATATCTACATCATGTTAACAAACGTCTAGAAGAAGAAGCAGAC
  AGACTTATTACTTACTTAGATCAGACCACCCAGAAGTCATTAATTGCTACTGTAGAAAAA
  CAACTTCTAGGTGAACACTTAACAGCAATTCTTCAGAAAGGTTTAAATAACCTCCTTGAT
  GAAAACCGAATTCAAGATTTGTCTCTTCTGTATCAGCTCTTCAGTAGAGTTCGAGGTGGA
  GTTCAGGTTCTTTTGCAGCAGTGGATCGAATATATCAAGGCATTTGGCAGCACTATTGTA
  ATTAATCCTGAAAAAGATAAAACCATGGTTCAAGAATTGCTGGATTTTAAAGATAAGGTT
  GACCATATAATTGATATCTGCTTTCTGAAGAATGAGAAATTTATCAATGCCATGAAAGAA
  GCATTTGAAACGTTCATTAACAAAAGACCAAATAAACCAGCTGAACTTATAGCTAAGTAT
  GTAGATTCAAAACTTCGTGCAGGCAACAAAGAAGCTACAGATGAAGAACTTGAGAAAATG
  TTGGATAAAATTATGATCATATTTAGATTTATCTATGGCAAGGATGTTTTTGAGGCCTTC
  TATAAGAAAGATTTAGCCAAGCGCCTGTTAGTCGGAAAGAGTGCATCTGTAGATGCTGAA
  AAATCAATGCTGTCCAAACTTAAACATGAATGCGGAGCTGCTTTCACCAGCAAACTTGAA
  GGAATGTTTAAAGACATGGAACTTTCTAAAGACATCATGATTCAGTTCAAACAGTATATG
  CAGAATCAGAATGTTCCGGGAAATATTGAGTTAACTGTGAATATCCTGACAATGGGCTAT
  TGGCCGACATATGTGCCTATGGAAGTTCATTTACCACCAGAGATGGTAAAACTTCAGGAG
  ATTTTCAAGACATTTTACCTAGGCAAACATAGTGGCAGGAAACTTCAGTGGCAGTCAACC
  ATAGGACACTGTGTGTTAAAAGCAGAATTTAAAGAGGGTAAAAAGGAACTCCAGGTCTCT
  CTTTTTCAAACACTGGTGCTGCTAATGTTTAATGAGGGAGAGGAGTTCAGTTTAGAAGAG
  ATCAAGCAGGCAACTGGAATAGAGGATGGAGAGTTAAGGAGAACACTGCAGTCATTAGCC
  TGTGGCAAAGCTAGAGTTCTGGCGAAAAATCCAAAGGGCAAAGACATTGAAGATGGTGAC
  AAGTTCATTTGTAATGATGATTTCAAACATAAACTTTTCAGGATAAAGATCAATCAAATC
  CAGATGAAAGAAACGGTTGAAGAACAAGCAAGCACTACAGAAAGAGTATTTCAAGACAGA
  CAGTATCAAATTGATGCTGCAATTGTTCGAATTATGAAGATGAGAAAGACACTTAGCCAC
  AATCTCCTTGTTTCAGAAGTGTACAACCAGTTGAAATTTCCAGTAAAGCCTGCTGATCTT
  AAGAAGAGAATAGAATCTTTAATTGACCGGGACTACATGGAAAGAGATAAAGAAAATCCA
  AACCAGTACAACTATATTGCATAGAATGTTGGCCTTGCAGCATTTGGTGTCATATGCAGT
  AGCCAGTGGATAAACTAACCTGTTGATTCAATATTATTTGACTCCTTTTTTACTACCGAT
  GACCAAATGAAGCAGTGTAATTAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003588 unedited
  GGGCAGTTCAAATTTGTATACGACTCACTATAGGNNCGGCCGCATAACTTCGTATAGCAT
  ACATTATACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGA
  GTTCAGTTTAGAAACTGCCAGTCTTGGTATAGAACAACCTAGGCTTATCTGTTTAAGTCC
  CATAGGTAGTATTATTAGAGAATAACCCAGGCTTTGGGAACTGTATAACTCTGAGATCGT
  TTGAAATTTTCGTTTTGTTTTTCTTTTGGCTCCAACCAGGCCTCTGTTGTTAGACTAATG
  GGGTTTCCCCTGCAGAGATTGGTCAGCCCTGCAGTCTATCATCCCGGAAGGTGTTAAATA
  CACATGAAAGCCAGCCTCGGCGGGCAGAACCTAGCCCGCCGAAAGGGCGGGCATTGCTAA
  AGTGTTTTCAAAAGGTCTTCCCAATCCTCTGCTTTAGACAGCTCGGACCTTAGATAGAAG
  AACACAACGGATCCTCCAGTGACTGACGACCCAAAGGACGGATGATGTCACAGTCATCTG
  GATCAGGAGATGGGAATGATGATGAGGCTACTACCTCTAAAGACGGTGGTTTTTCTTCCC
  CCAGTCCCTCAGCTGCTGCTGCTGCTCAGGAGGTCAGATCTGCCACTGATGGTAATACCA
  GCACCACTCCGCCCACCTCTGCCAAGAAGAGAAAGTTAAACAGCAGCAGCAGTAGCAGCA
  GTAACAGTAGTAACGAGAGAGAAGACTTTGATTCCACCTCTTTCTCCTCTTCCACTCCTC
  CTTTACAACCCAGGNATTCGGCATCCCCTTTCACCTCGTCCTTCTGCCTGGGGGTTTCAG
  TGGCTGCTTNCAGCCCN
  
• Restriction Sites: Please inquire
• ACCN: NM_003588
• ORF Size: 2742 bp
• Insert Size: 3300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003588.2, NP_003579.2
• RefSeq Size: 3278
• RefSeq ORF: 2742
• Locus ID: 8450
• Domains: CULLIN
• Protein Pathways: Nucleotide excision repair, Ubiquitin mediated proteolysis
• Gene Summary: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).