DISC1 (NM_001012959) Human Untagged Clone

CAT#: SC301731

DISC1 (untagged)-Human disrupted in schizophrenia 1 (DISC1), transcript variant S

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DISC1
• Synonyms: C1orf136; SCZD9
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001012959 edited
  AGCGGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCGCCGGCGGCGGCGG
  CGTGAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCG
  GCGGCTGGCACGGAGGCCGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCT
  TTCCCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTGGCGAGGAGTCCCA
  CCACTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAG
  CCCTGTTTCCAAGAGTGCAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCA
  CTTTGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTAGCTGGCCGTGTGG
  CCCTGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGA
  CGCCAGCTGGGAGGCAGCCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCT
  GCCATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCCCTGAGGTCCCCCC
  AACCCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCT
  TGGCTCTGCCGGGGAACGTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTC
  CCATTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGGACGGGCCTCACGA
  GGACCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTT
  GGCCCAGGCCGCAAGGAACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACAT
  GGACCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTGGTGGTGATGGGAG
  CAGCGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCT
  GCGGGACTGCCTGCTGAGAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACT
  TCAGAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAGCTGAGACGTTACA
  ACAAAGATTAGAAGACCTGGAACAAGAGAAAATCAGCCTGCACTTTCAACTTCCTTCAAG
  GCAGCCAGCTCTTAGCAGTTTCCTGGGTCACCTGGCAGCACAAGTCCAGGCTGCCTTGCG
  CCGTGGGGCCACTCAGCAGGCCAGCGGAGATGACACCCACACCCCACTGAGAATGGAGCC
  GAGGCTGTTGGAACCCACTGCTCAGGACAGCTTGCACGTGTCCATCACGAGACGAGACTG
  GCTTCTTCAGGAAAAGCAGCAGCTACAGAAAGAAATTGAAGCTCTCCAAGCAAGGATGTT
  TGTGCTGGAAGCCAAAGATCAACAGCTGAGAAGGGAAATAGAGGAGCAAGAGCAGCAACT
  CCAGTGGCAGGGCTGCGACCTGACCCCACTGGTGGGCCAGCTGTCCCTGGGTCAGCTGCA
  GGAGGTCAGCAAGGCCTTGCAGGACACCCTGGCCTCAGCCGGTCAGATTCCCTTCCATGC
  AGAGCCACCGGAAACCATAAGGAGCCTCCAGGAAAGAATAAAATCCCTCAACTTGTCACT
  TAAAGAAATCACTACTAAGGTGTGTATGAGTGAGAAATTCTGCAGCACCCTGAGGAAGAA
  AGTTAACGATATTGAAACCCAACTACCAGCCTTGCTTGAAGCCAAAATGCATGCCATATC
  AGGAAACCATTTCTGGACGGCTAAAGACCTCACCGAGGAGATTAGATCATTAACATCAGA
  GAGAGAAGGGCTGGAGGGACTCCTCAGCAAGCTGTTGGTGTTGAGTTCCAGGAATGTCAA
  AAAGCTGGGAAGTGTTAAAGAAGATTACAACAGACTGAGAAGAGAAGTGGAGCACCAGGA
  GACTGCCTATGGATATAAGTACTGTGATGCAGAGTCCTGGACACAGAGAAGTCAGCAACT
  TGCCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001012959 unedited
  GGTTAAATATTTGTATACGACTCACTATAGGCGGCCGACGATTCGCCCTTAGCGGGGCGC
  ATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCGCCGGCGGCGGCGGCGTGAGCCAC
  CGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCA
  CGGAGGCCGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCA
  GTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTGGCGAGGAGTCCCACCACTCGGAG
  TCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCC
  AAGAGTGCAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATT
  CAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTAGCTGGCCGTGTGGCCCTGGGAGT
  GCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGG
  GAGGCAGCCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCA
  GAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCCCTGAGGTCCCCCCAACCCCTCCT
  GGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCC
  GGGGAACGTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAG
  AGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGGACGGGCCTCACGAGGACCCGCGA
  TGTCTCTCTCGGCCCCNCAGTCTCTTGGCTACACNGGTCTCTGCAGACTTGGGCCAAGCC
  GCAAGGAACAACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001012959 unedited
  ACACCATTGGNGATGGCACTTCCAGGNCCAGNAAAGCACTGGGGNAGGGTCACAGGNATG
  CCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGATCAGG
  CAAGTTGCTGACTTCTCTGTGTCCAGGACTCTGCATCACAGTACTTATATCCATAGGCAG
  TCTCCTGGTGCTCCACTTCTCTTCTCAGTCTGTTGTAATCTTCTTTAACACTTCCCAGCT
  TTTTGACATTCCTGGAACTCAACACCAACAGCTTGCTGAGGAGTCCCTCCAGCCCTTCTC
  TCTCTGATGTTAATGATCTAATCTCCTCGGTGAGGTCTTTAGCCGTCCAGAAATGGTTTC
  CTGATATGGCATGCATTTTGGCTTCAAGCAAGGCTGGTAGTTGGGTTTCAATATCGTTAA
  CTTTCTTCCTCAGGGTGCTGCAGAATTTCTCACTCATACACACCTTAGTAGTGATTTCTT
  TAAGTGACAAGTTGAGGGATTTTATTCTTTCCTGGAGGCTCCTTATGGTTTCCGGTGGCT
  CTGCATGGAAGGGAATCTGACCGGCTGAGGCCAGGGTGTCCTGCAAGGCCTTGCTGACCT
  CCTGCAGCTGACCCAGGGACAGCTGGCCCACCAGTGGGGTCAGGTCGCAGCCCTGCCACT
  GGAGTTGCTGCTCTTGCTCCTCTATTTCCCTTCTCAGCTGTTGATCTTTGGCTTCCAGCA
  CAAACATCCTTGCTTGGAGAGCTTCAAATTTCTTCTGTAGCTGCTGCTTTTCCTGAAGAA
  ACCAGTCTCGTCTCGTGATGGACACGTGCAAGCTGTCCTGAGCAGTGGGTCCAACAGCCT
  CGGCTCCATTCTCAGTGGGTGTGGGGTGTCATCTCCGCTGGN
  
• Restriction Sites: Please inquire
• ACCN: NM_001012959
• ORF Size: 2037 bp
• Insert Size: 2100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_001012959.1, NP_001012977.1
• RefSeq Size: 2230
• RefSeq ORF: 2037
• Locus ID: 27185
• Gene Summary: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (S) lacks several 3' exons but has an alternate 3' exon, as compared to variant L. The resulting isoform (S, also known as the 'Short' isoform) is shorter and has a distinct C-terminus, as compared to isoform L.