BMP1 (NM_001199) Human Untagged Clone

CAT#: SC302989

BMP1 (untagged)-Human bone morphogenetic protein 1 (BMP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BMP1
• Synonyms: OI13; PCOLC; PCP; PCP2; TLD
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001199 edited
  AAAGGGAGAGGGAGACGGCTGGAGCCCGAGGACGAGCGCGGAGCCGCGGACCGAGCGGGG
  GGCGGGAGACAGGAAGGAGGGAGGCGAGCAGAGGGAAGGGGAAGAGGTCGGGGAGCGAGG
  GCGGGAGCGGTCGCGGTCGCGATCGAGCAAGCAAGCGGGCGAGAGGACGCCCTCCCCTGG
  CCTCCAGTGCGCCGCTTCCCTCGCCGCCGCCCCGCCAGCATGCCCGGCGTGGCCCGCCTG
  CCGCTGCTGCTCGGGCTGCTGCTGCTCCCGCGTCCCGGCCGGCCGCTGGACTTGGCCGAC
  TACACCTATGACCTGGCGGAGGAGGACGACTCGGAGCCCCTCAACTACAAAGACCCCTGC
  AAGGCGGCTGCCTTTCTTGGGGACATTGCCCTGGACGAAGAGGACCTGAGGGCCTTCCAG
  GTACAGCAGGCTGTGGATCTCAGACGGCACACAGCTCGTAAGTCCTCCATCAAAGCTGCA
  GTTCCAGGAAACACTTCTACCCCCAGCTGCCAGAGCACCAACGGGCAGCCTCAGAGGGGA
  GCCTGTGGGAGATGGAGAGGTAGATCCCGTAGCCGGCGGGCGGCGACGTCCCGACCAGAG
  CGTGTGTGGCCCGATGGGGTCATCCCCTTTGTCATTGGGGGAAACTTCACTGGTAGCCAG
  AGGGCAGTCTTCCGGCAGGCCATGAGGCACTGGGAGAAGCACACCTGTGTCACCTTCCTG
  GAGCGCACTGACGAGGACAGCTATATTGTGTTCACCTATCGACCTTGCGGGTGCTGCTCC
  TACGTGGGTCGCCGCGGCGGGGGCCCCCAGGCCATCTCCATCGGCAAGAACTGTGACAAG
  TTCGGCATTGTGGTCCACGAGCTGGGCCACGTCGTCGGCTTCTGGCACGAACACACTCGG
  CCAGACCGGGACCGCCACGTTTCCATCGTTCGTGAGAACATCCAGCCAGGGCAGGAGTAT
  AACTTCCTGAAGATGGAGCCTCAGGAGGTGGAGTCCCTGGGGGAGACCTATGACTTCGAC
  AGCATCATGCATTACGCTCGGAACACATTCTCCAGGGGCATCTTCCTGGATACCATTGTC
  CCCAAGTATGAGGTGAACGGGGTGAAACCTCCCATTGGCCAAAGGACACGGCTCAGCAAG
  GGGGACATTGCCCAAGCCCGCAAGCTTTACAAGTGCCCAGCCTGTGGAGAGACCCTGCAA
  GACAGCACAGGCAACTTCTCCTCCCCTGAATACCCCAATGGCTACTCTGCTCACATGCAC
  TGCGTGTGGCGCATCTCTGTCACACCCGGGGAGAAGATCATCCTGAACTTCACGTCCCTG
  GACCTGTACCGCAGCCGCCTGTGCTGGTACGACTATGTGGAGGTCCGAGATGGCTTCTGG
  AGGAAGGCGCCCCTCCGAGGCCGCTTCTGCGGGTCCAAACTCCCTGAGCCTATCGTCTCC
  ACTGACAGCCGCCTCTGGGTTGAATTCCGCAGCAGCAGCAATTGGGTTGGAAAGGGCTTC
  TTTGCAGTCTACGAAGCCATCTGCGGGGGTGATGTGAAAAAGGACTATGGCCACATTCAA
  TCGCCCAACTACCCAGACGATTACCGGCCCAGCAAAGTCTGCATCTGGCGGATCCAGGTG
  TCTGAGGGCTTCCACGTGGGCCTCACATTCCAGTCCTTTGAGATTGAGCGCCACGACAGC
  TGTGCCTACGACTATCTGGAGGTGCGCGACGGGCACAGTGAGAGCAGCACCCTCATCGGG
  CGCTACTGTGGCTATGAGAAGCCTGATGACATCAAGAGCACGTCCAGCCGCCTCTGGCTC
  AAGTTCGTCTCTGACGGGTCCATTAACAAAGCGGGCTTTGCCGTCAACTTTTTCAAAGAG
  GTGGACGAGTGCTCTCGGCCCAACCGCGGGGGCTGTGAGCAGCGGTGCCTCAACACCCTG
  GGCAGCTACAAGTGCAGCTGTGACCCCGGGTACGAGCTGGCCCCAGACAAGCGCCGCTGT
  GAGGCTGCCTGTGGCGGATTCCTCACCAAGCTCAACGGCTCCATCACCAGCCCGGGCTGG
  CCCAAGGAGTACCCCCCCAACAAGAACTGCATCTGGCAGCTGGTGGCCCCCACCCAGTAC
  CGCATCTCCCTGCAGTTTGACTTCTTTGAGACAGAGGGCAATGATGTGTGCAAGTACGAC
  TTCGTGGAGGTGCGCAGTGGACTCACAGCTGACTCCAAGCTGCATGGCAAGTTCTGTGGT
  TCTGAGAAGCCCGAGGTCATCACCTCCCAGTACAACAACATGCGCGTGGAGTTCAAGTCC
  GACAACACCGTGTCCAAAAAGGGCTTCAAGGCCCACTTCTTCTCAGAAAAGAGGCCAGCT
  CTGCAGCCCCCTCGGGGACGCCCCCACCAGCTCAAATTCCGAGTGCAGAAAAGAAACCGG
  ACCCCCCAGTGAGGCCTGCCAGGCCTCCCGGACCCCTTGTTACTCAGGAACCTCACCTTG
  GACGGAATGGGATGGGGGCTTCGGTGCCCACCAACCCCCCACCTCCACTCTGCCATTCCG
  GCCCACCTCCCTCTGGCCGGACAGAACTGGTGCTCTCTTCTCCCCACT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001199 unedited
  CGTCACATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCAGAGGAAAGGAGAGGG
  AGACGGCTGGAGCCCGAGGACGAGCGCGGAGCCGCGGACCGAGCGGGGGGCGGGAGACAG
  GAAGGAGGGAGGCGAGCAGAGGGAAGGGGAAGAGGTCGGGGAGCGAGGGCGGGAGCGGTC
  GCGGTCGCGATCGAGCAAGCAAGCGGGCGAGAGGACGCCCTCCCCTGGCCTCCAGTGCGC
  CGCTTCCCTCGCCGCCGCCCCGCCAGCATGCCCGGCGTGGCCCGCCTGCCGCTGCTGCTC
  GGGCTGCTGCTGCTCCCGCGTCCCGGCCGGCCGCTGGACTTGGCCGACTACACCTATGAC
  CTGGCGGAGGAGGACGACTCGGAGCCCCTCAACTACAAAGACCCCTGCAAGGCGGCTGCC
  TTTCTTGGGGACATTGCCCTGGACGAAGAGGACCTGAGGGCCTTCCAGGTACAGCAGGCT
  GTGGATCTCAGACGGCACACAGCTCGTAAGTCCTCCATCAAAGCTGCAGTTCCAGGAAAC
  ACTTCTACCCCCAGCTGCCAGAGCACCAACGGGCAGCCTCAGAGGGGAGCCTGTGGGAGA
  TGGAGAGGTAGATCCCGTAGCCGGCGGGCGGCGACGTCCCGACCAGAGCGTGTGTGGCCC
  GATGGGGTCATCCCCTTTGTCATTGGGGGAAACTTCACTGGTAGCCAGAGGGCAGTCTTT
  CCGCAGGGCCATGAGCACTGGGAGAAGCACACCTGTGTCACCTTCCTGGAGCGCACTGAC
  GAGGACAGCTATATTGTGTTCACCTATCGACCTTGCGGGTGCTGCNTCTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001199 unedited
  CCCATTGGNGATGGCACTTCCAGGNCCAGNANGAGCCTGGGGNAGGGTCACAGGGATGCC
  ACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGATGCATGCTCGAG
  CGGCCGCCAGTGTGATGGATATCTGCAGAATTCGCCCTTGAGATCTAGAGTGGGGAGAAG
  AGAGCACCAGTTCTGTCCGGCCAGAGGGAGGTGGGCCGGAATGGCAGAGTGGAGGTGGGG
  GGTTGGTGGGCACCGAAGCCCCCATCCCATTCCGTCCAAGGTGAGGTTCCTGAGTAACAA
  GGGGTCCGGGAGGCCTGGCAGGCCTCACTGGGGGGTCCGGTTTCTTTTCTGCACTCGGAA
  TTTGAGCTGGTGGGGGCGTCCCCGAGGGGGCTGCAGAGCTGGCCTCTTTTCTGAGAAGAA
  GTGGGCCTTGAAGCCCTTTTTGGACACGGTGTTGTCGGACTTGAACTCCACGCGCATGTT
  GTTGTACTGGGAGGTGATGACCTCGGGCTTCTCAGAACCACAGAACTTGCCATGCAGCTT
  GGAGTCAGCTGTGAGTCCACTGCGCACCTCCACGAAGTCGTACTTGCACACATCATTGCC
  CTCTGTCTCANAGAAGTCAAACTGCAGGGAGATGCGGTACTGGGTGGGGGCCACCAGCTG
  CCAGATGCAGTTCTTGTTGGGGGGGTACTCCTTGGGCCAGCCCCGGCTGGTGATGGAGCC
  GTTGAGCTTGGTGAGGAATCCGCCACAGGCAGCCTCACAGCGGCGCTTGTCTGGGGCCAG
  CTCGTACCCGAGTCACAGCTGCACTTGTAGCTGCCCAAGGTGTTGAAGCACCGCTGCTCA
  CAGCCCCCGCGGTTGGGCCGAAAGCCCTCGTCCACCTCTTGAAAAAGTTTGACGCAAAAC
  CCGGCTT
  
• Restriction Sites: Please inquire
• ACCN: NM_001199
• Insert Size: 2600 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001199.1, NP_001190.1
• RefSeq Size: 2487 bp
• RefSeq ORF: 2193 bp
• Locus ID: 649
• Cytogenetics: 8p21.3
• Domains: CUB, Astacin, EGF_CA, ZnMc, EGF, EGF
• Protein Families: Druggable Genome, Protease
• Gene Summary: 'This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008]'
  Transcript Variant: This variant (1, also known as BMP1-1) represents the shortest transcript and encodes the shorter isoform (1).