CELSR2 (NM_001408) Human Untagged Clone

CAT#: SC303012

CELSR2 (untagged)-Human cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) (CELSR2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CELSR2
• Synonyms: ADGRC2; CDHF10; EGFL2; Flamingo1; MEGF3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001408, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCGGAGCCCGGCCACCGGCGTCCCCCTCCCAACGCCGCCGCCGCCGCTGCTGCTGCTGTTGCTGCTGC
  TGCTGCCGCCGCCACTATTGGGAGACCAAGTGGGGCCCTGTCGTTCCTTGGGGTCCAGGGGACGAGGCTC
  TTCGGGGGCCTGCGCCCCCATGGGCTGGCTCTGTCCATCCTCAGCGTCGAACCTCTGGCTCTACACCAGC
  CGCTGCAGGGATGCGGGCACTGAGCTGACTGGCCACCTGGTACCCCACCACGATGGCCTGAGGGTTTGGT
  GTCCAGAATCCGAGGCCCATATTCCCCTACCACCAGCTCCTGAAGGCTGCCCCTGGAGCTGTCGCCTCCT
  GGGCATTGGAGGCCACCTTTCCCCACAGGGCAAGCTCACACTGCCCGAGGAGCACCCGTGCTTAAAGGCT
  CCACGGCTCAGATGCCAGTCCTGCAAGCTGGCACAGGCCCCCGGGCTCAGGGCAGGGGAAAGGTCACCAG
  AAGAGTCCCTGGGTGGGCGTCGGAAAAGGAATGTAAATACAGCCCCCCAGTTCCAGCCCCCCAGCTACCA
  GGCCACAGTGCCGGAGAACCAGCCAGCAGGCACCCCTGTTGCATCCCTGAGGGCCATCGACCCGGACGAG
  GGTGAGGCAGGTCGACTGGAGTACACCATGGATGCCCTCTTTGATAGCCGCTCCAACCAGTTCTTCTCCC
  TGGACCCAGTCACTGGTGCAGTAACCACAGCCGAGGAGCTGGATCGTGAGACCAAGAGCACCCACGTCTT
  CAGGGTCACGGCGCAGGACCACGGCATGCCCCGACGAAGTGCCCTGGCTACACTCACCATCTTGGTTACT
  GACACCAATGACCATGACCCTGTGTTCGAGCAGCAGGAGTACAAGGAGAGCCTCAGGGAGAACCTGGAGG
  TTGGCTATGAGGTGCTCACTGTCAGGGCCACGGATGGTGATGCCCCTCCCAATGCCAATATTCTGTACCG
  CCTGCTGGAGGGGTCTGGGGGCAGCCCCTCTGAAGTCTTTGAGATCGACCCTCGCTCTGGGGTGATCCGA
  ACCCGTGGCCCTGTGGATCGGGAAGAGGTGGAATCCTACCAGCTGACGGTAGAGGCAAGTGACCAGGGTC
  GGGACCCGGGTCCTCGGAGTACCACAGCCGCTGTTTTCCTTTCTGTGGAGGATGACAATGATAATGCCCC
  CCAGTTTAGTGAGAAGCGCTATGTGGTCCAGGTGAGGGAGGATGTGACTCCAGGGGCCCCAGTACTCCGA
  GTCACAGCCTCGGATCGAGACAAGGGGAGCAATGCCGTGGTGCACTATAGCATCATGAGTGGCAATGCTC
  GGGGACAGTTTTATCTGGATGCCCAGACTGGAGCTCTGGATGTGGTGAGCCCTCTTGACTATGAGACGAC
  CAAGGAGTACACCCTACGGGTGCGAGCACAGGATGGTGGCCGTCCCCCACTCTCTAATGTCTCTGGCTTG
  GTGACAGTACAGGTCCTGGATATCAACGACAATGCCCCCATCTTCGTCAGCACCCCTTTCCAGGCTACTG
  TCCTGGAGAGTGTCCCCTTAGGCTACCTGGTTCTCCATGTCCAGGCTATCGACGCTGATGCTGGTGACAA
  TGCCCGCCTGGAATACCGCCTTGCTGGGGTGGGACATGACTTCCCCTTCACCATCAACAATGGCACAGGC
  TGGATCTCTGTGGCTGCTGAACTGGACCGGGAGGAAGTTGATTTCTACAGCTTTGGGGTAGAAGCTCGAG
  ACCATGGCACTCCAGCACTCACTGCCTCGGCCAGTGTCAGCGTGACTGTCCTGGATGTCAACGACAACAA
  TCCAACCTTTACCCAACCAGAGTACACAGTGCGGCTCAATGAGGATGCAGCTGTGGGCACCAGCGTGGTG
  ACGGTGTCAGCTGTGGACCGTGATGCTCATAGTGTCATCACCTACCAGATCACCAGTGGCAATACTCGAA
  ACCGCTTCTCCATCACCAGCCAAAGTGGTGGTGGGCTGGTATCCCTTGCCCTGCCACTGGACTACAAACT
  TGAGCGGCAGTATGTGTTGGCTGTTACCGCCTCCGATGGCACTCGGCAGGACACGGCACAGATTGTGGTG
  AATGTCACCGACGCCAACACCCATCGTCCTGTCTTTCAGAGCTCCCACTATACAGTGAATGTTAATGAGG
  ACCGGCCGGCAGGCACCACGGTGGTGCTGATCAGCGCCACGGATGAGGACACAGGTGAGAATGCCCGCAT
  CACCTACTTCATGGAGGACAGCATCCCCCAGTTCCGCATCGATGCAGACACGGGGGCTGTCACCACCCAG
  GCTGAGCTGGACTATGAAGACCAAGTGTCTTACACCCTGGCCATTACTGCTCGGGACAATGGCATTCCCC
  AGAAGTCCGACACCACCTACCTGGAGATCCTGGTGAACGACGTGAATGACAATGCCCCTCAGTTCCTGCG
  AGACTCCTACCAGGGCAGTGTCTATGAGGATGTGCCACCCTTCACTAGCGTCCTGCAGATCTCAGCCACT
  GATCGTGATTCTGGACTTAATGGCAGGGTCTTCTACACCTTCCAAGGAGGCGACGATGGAGACGGTGACT
  TTATTGTTGAGTCCACGTCAGGCATCGTGCGAACGCTACGGAGGCTGGATCGAGAGAACGTGGCCCAGTA
  TGTCTTGCGGGCATATGCAGTGGACAAGGGGATGCCCCCAGCCCGCACACCTATGGAAGTGACAGTCACT
  GTGTTGGATGTGAATGACAATCCCCCTGTCTTTGAGCAGGATGAGTTTGATGTGTTTGTGGAAGAGAACA
  GCCCCATTGGGCTAGCCGTGGCCCGGGTCACAGCCACTGACCCCGATGAAGGCACCAATGCCCAGATTAT
  GTACCAGATTGTGGAGGGCAACATCCCTGAGGTCTTTCAGCTGGACATCTTCTCCGGGGAGCTGACAGCC
  CTGGTAGACTTAGACTACGAGGACCGGCCTGAGTACGTCCTGGTCATCCAGGCCACGTCAGCTCCTCTGG
  TGAGCCGGGCTACAGTCCACGTCCGCCTCCTTGACCGCAATGACAACCCACCAGTGCTGGGCAACTTTGA
  GATCCTTTTCAACAACTATGTCACCAATCGCTCAAGCAGCTTCCCTGGGGGTGCCATTGGCCGAGTACCT
  GCCCATGACCCTGATATCTCAGATAGTCTGACTTACAGCTTTGAGCGGGGAAATGAACTCAGCCTGGTCC
  TGCTCAATGCCTCCACGGGTGAGCTGAAGCTAAGCCGCGCACTGGACAACAACCGGCCTCTGGAGGCCAT
  CATGAGCGTGCTGGTGTCAGACGGCGTACACAGCGTGACCGCCCAGTGCGCGCTGCGTGTGACCATCATC
  ACCGATGAGATGCTCACCCACAGCATCACGCTGCGCCTGGAGGACATGTCACCCGAGCGCTTCCTGTCAC
  CACTGCTAGGCCTCTTCATCCAGGCGGTGGCCGCCACGCTGGCCACGCCACCGGACCACGTGGTGGTCTT
  CAACGTACAGCGGGACACCGACGCCCCCGGGGGCCACATCCTCAACGTGAGCCTGTCGGTGGGCCAGCCG
  CCAGGGCCCGGGGGCGGGCCGCCCTTCCTGCCCTCTGAGGACCTGCAGGAGCGCCTATACCTCAACCGCA
  GCCTGCTGACGGCCATCTCGGCACAGCGCGTGCTGCCCTTCGACGACAACATCTGCCTGCGGGAGCCCTG
  CGAGAACTACATGCGCTGCGTGTCGGTGCTGCGCTTCGACTCCTCCGCGCCCTTCATCGCCTCCTCCTCC
  GTGCTCTTCCGGCCCATCCACCCCGTCGGAGGGCTGCGCTGCCGCTGCCCGCCCGGCTTCACGGGTGACT
  ACTGCGAGACCGAGGTGGACCTCTGCTACTCGCGGCCCTGTGGCCCCCACGGGCGCTGCCGCAGCCGCGA
  GGGCGGCTACACCTGCCTCTGTCGTGATGGCTACACGGGTGAGCACTGTGAGGTGAGTGCTCGCTCAGGC
  CGTTGCACCCCGGGTGTCTGCAAGAATGGGGGCACCTGTGTCAACCTGCTGGTGGGCGGTTTCAAGTGCG
  ATTGCCCATCTGGAGACTTCGAGAAGCCCTACTGCCAGGTGACCACGCGCAGCTTCCCCGCCCACTCCTT
  CATCACCTTTCGCGGCCTGCGCCAGCGTTTCCACTTCACCCTGGCCCTCTCGTTTGCCACAAAGGAGCGC
  GACGGGTTGCTGTTGTACAATGGGCGTTTCAATGAGAAGCATGACTTTGTGGCCCTCGAGGTGATCCAGG
  AGCAGGTCCAGCTCACCTTCTCTGCAGGGGAGTCAACCACCACGGTGTCCCCATTCGTGCCCGGAGGAGT
  CAGTGATGGCCAGTGGCATACGGTGCAGCTGAAATACTACAATAAGCCACTGTTGGGTCAGACAGGGCTC
  CCACAGGGCCCATCAGAGCAGAAGGTGGCTGTGGTGACCGTGGATGGCTGTGACACAGGAGTGGCCTTGC
  GCTTCGGATCTGTCCTGGGCAACTACTCCTGTGCTGCCCAGGGCACCCAGGGTGGCAGCAAGAAGTCTCT
  GGATCTGACGGGGCCCCTGCTACTAGGCGGGGTGCCTGACCTGCCCGAGAGCTTCCCAGTCCGAATGCGG
  CAGTTCGTGGGCTGCATGCGGAACCTGCAGGTGGACAGCCGGCACATAGACATGGCTGACTTCATTGCCA
  ACAATGGCACCGTGCCTGGCTGCCCTGCCAAGAAGAACGTGTGTGACAGCAACACTTGCCACAATGGGGG
  CACTTGCGTGAACCAGTGGGACGCGTTCAGCTGCGAGTGCCCCCTGGGCTTTGGGGGCAAGAGCTGCGCC
  CAGGAAATGGCCAATCCACAGCACTTCCTGGGCAGCAGCCTGGTGGCCTGGCATGGCCTCTCGCTGCCCA
  TCTCCCAACCCTGGTACCTCAGCCTCATGTTCCGCACGCGCCAGGCCGACGGTGTCCTGCTGCAGGCCAT
  CACCAGGGGGCGCAGCACCATCACCCTACAGCTACGAGAGGGCCACGTGATGCTGAGCGTGGAGGGCACA
  GGGCTTCAGGCCTCCTCTCTCCGTCTGGAGCCAGGCCGGGCCAATGACGGTGACTGGCACCATGCACAGC
  TGGCACTGGGAGCCAGCGGGGGGCCCGGCCATGCCATTCTGTCCTTCGATTATGGGCAGCAGAGAGCAGA
  GGGCAACCTGGGCCCCCGGCTGCATGGTCTGCACCTGAGCAACATAACAGTGGGCGGAATACCTGGGCCA
  GCCGGCGGTGTGGCCCGTGGCTTTCGGGGCTGTTTGCAGGGTGTGCGGGTGAGCGATACGCCGGAGGGGG
  TTAACAGCCTGGATCCCAGCCATGGGGAGAGCATCAACGTGGAGCAAGGCTGTAGCCTGCCTGACCCTTG
  TGACTCAAACCCGTGTCCTGCTAACAGCTATTGCAGCAACGACTGGGACAGCTATTCCTGCAGCTGTGAT
  CCAGGTTACTATGGTGACAACTGTACTAATGTGTGTGACCTGAACCCGTGTGAGCACCAGTCTGTGTGTA
  CCCGCAAGCCCAGTGCCCCCCATGGCTATACCTGCGAGTGTCCCCCAAATTACCTTGGGCCATACTGTGA
  GACCAGGATTGACCAGCCTTGTCCCCGTGGCTGGTGGGGACATCCCACATGTGGCCCATGCAACTGTGAT
  GTCAGCAAAGGCTTTGACCCAGACTGCAACAAGACAAGCGGCGAGTGCCACTGCAAGGAGAACCACTACC
  GGCCCCCAGGCAGCCCCACCTGCCTCTTGTGTGACTGCTACCCCACAGGCTCCTTGTCCAGAGTCTGTGA
  CCCTGAGGATGGCCAGTGTCCATGCAAGCCAGGTGTCATCGGGCGTCAGTGTGACCGCTGTGACAACCCT
  TTTGCTGAGGTCACCACCAATGGCTGTGAAGTGAATTATGACAGCTGCCCACGAGCGATTGAGGCTGGGA
  TCTGGTGGCCCCGTACCCGCTTCGGGCTGCCTGCTGCTGCTCCCTGTCCCAAAGGCTCCTTTGGGACTGC
  TGTGCGCCACTGTGATGAGCACAGGGGGTGGCTCCCCCCAAACCTCTTCAACTGCACGTCCATCACCTTC
  TCAGAACTGAAGGGCTTCGCTGAGCGGCTACAGCGGAATGAGTCAGGCCTAGACTCAGGGCGCTCCCAGC
  AGCTAGCCCTGCTCCTGCGCAACGCCACGCAGCACACAGCTGGCTACTTCGGCAGCGACGTCAAGGTGGC
  CTACCAGCTGGCCACGCGGCTGCTGGCCCACGAGAGCACCCAGCGGGGCTTTGGGCTGTCTGCCACACAG
  GACGTGCACTTCACTGAGAATCTGCTGCGGGTGGGCAGCGCCCTCCTGGACACAGCCAACAAGCGGCACT
  GGGAGCTGATCCAGCAGACAGAGGGTGGCACCGCCTGGCTGCTCCAGCACTATGAGGCCTACGCCAGTGC
  CCTGGCCCAGAACATGCGGCACACCTACCTAAGCCCCTTCACCATCGTCACGCCCAACATTGTCATCTCC
  GTAGTGCGCTTGGACAAAGGGAACTTTGCTGGGGCCAAGCTGCCCCGCTACGAGGCCCTGCGTGGGGAGC
  AGCCCCCGGACCTTGAGACAACAGTCATTCTGCCTGAGTCTGTCTTCAGAGAGACGCCCCCCGTGGTCAG
  GCCCGCAGGCCCCGGAGAGGCCCAGGAGCCAGAGGAGCTGGCACGGCGACAGCGACGGCACCCGGAGCTG
  AGCCAGGGTGAGGCTGTGGCCAGCGTCATCATCTACCGCACCCTGGCCGGGCTACTGCCTCATAACTATG
  ACCCTGACAAGCGCAGCTTGAGAGTCCCCAAACGCCCGATCATCAACACACCCGTGGTGAGCATCAGCGT
  CCATGATGATGAGGAGCTTCTGCCCCGGGCCCTGGACAAACCCGTCACGGTGCAGTTCCGCCTGCTGGAG
  ACAGAGGAGCGGACCAAGCCCATCTGTGTCTTCTGGAACCATTCAATCCTGGTCAGTGGCACAGGTGGCT
  GGTCGGCCAGAGGCTGTGAAGTCGTCTTCCGCAATGAGAGCCACGTCAGCTGCCAGTGCAACCACATGAC
  GAGCTTCGCTGTGCTCATGGACGTTTCTCGGCGGGAGAATGGGGAGATCCTGCCACTGAAGACACTGACA
  TACGTGGCTCTAGGTGTCACCTTGGCTGCCCTTCTGCTCACCTTCTTCTTCCTCACTCTCTTGCGTATCC
  TGCGCTCCAACCAACACGGCATCCGACGTAACCTGACAGCTGCCCTGGGCCTGGCTCAGCTGGTCTTCCT
  CCTGGGAATCAACCAGGCTGACCTCCCTTTTGCCTGCACAGTCATTGCCATCCTGCTGCACTTCCTGTAC
  CTCTGCACCTTTTCCTGGGCTCTGCTGGAGGCCTTGCACCTGTACCGGGCACTCACTGAGGTGCGCGATG
  TCAACACCGGCCCCATGCGCTTCTACTACATGCTGGGCTGGGGCGTGCCTGCCTTCATCACAGGGCTAGC
  CGTGGGCCTGGACCCCGAGGGCTACGGGAACCCTGACTTCTGCTGGCTCTCCATCTATGACACGCTCATC
  TGGAGTTTTGCTGGCCCGGTGGCCTTTGCCGTCTCGATGAGTGTCTTCCTGTACATCCTGGCGGCCCGGG
  CCTCCTGTGCTGCCCAGCGGCAGGGCTTTGAGAAGAAAGGTCCTGTCTCGGGCCTGCAGCCCTCCTTCGC
  CGTCCTCCTGCTGCTGAGCGCCACGTGGCTGCTGGCACTGCTCTCTGTCAACAGCGACACCCTCCTCTTC
  CACTACCTCTTTGCTACCTGCAATTGCATCCAGGGCCCCTTCATCTTCCTCTCCTATGTGGTGCTTAGCA
  AGGAGGTCCGGAAAGCACTCAAGCTTGCCTGCAGCCGCAAGCCCAGCCCTGACCCTGCTCTGACCACCAA
  GTCCACCCTGACCTCGTCCTACAACTGCCCCAGCCCCTACGCAGATGGGCGGCTGTACCAGCCCTACGGA
  GACTCGGCCGGCTCTCTGCACAGCACCAGTCGCTCGGGCAAGAGTCAGCCCAGCTACATCCCCTTCTTGC
  TGAGGGAGGAGTCCGCACTGAACCCTGGCCAAGGGCCCCCTGGCCTGGGGGATCCAGGCAGCCTGTTCCT
  GGAAGGTCAAGACCAGCAGCATGATCCTGACACGGACTCCGACAGTGACCTGTCCTTAGAAGACGACCAG
  AGTGGCTCCTATGCCTCTACCCACTCATCAGACAGTGAGGAGGAAGAAGAGGAGGAGGAAGAGGAGGCCG
  CCTTCCCTGGAGAGCAGGGCTGGGATAGCCTGCTGGGGCCTGGAGCAGAGAGACTGCCCCTGCACAGTAC
  TCCCAAGGATGGGGGCCCAGGGCCTGGCAAGGCCCCCTGGCCAGGAGACTTTGGGACCACAGCAAAAGAG
  AGTAGTGGCAACGGGGCCCCTGAGGAGCGGCTGCGGGAGAATGGAGATGCCCTGTCTCGAGAGGGGTCCC
  TAGGCCCCCTTCCAGGCTCTTCTGCCCAGCCTCACAAAGGCATCCTTAAGAAGAAGTGTCTGCCCACCAT
  CAGCGAGAAGAGCAGCCTCCTGCGGCTCCCCCTGGAGCAATGCACAGGGTCTTCCCGGGGCTCCTCCGCT
  AGTGAGGGCAGCCGGGGAGGCCCCCCTCCCCGCCCACCGCCCCGGCAGAGCCTCCAGGAGCAGCTGAACG
  GGGTCATGCCCATCGCCATGAGCATCAAGGCAGGCACGGTGGATGAGGACTCGTCAGGCTCCGAATTTCT
  CTTCTTTAACTTCCTGCATTAA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001408
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001408.2, NP_001399.1
• RefSeq Size: 10540 bp
• RefSeq ORF: 8772 bp
• Locus ID: 1952
• Cytogenetics: 1p13.3
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: 'The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008]'