BAG2 (NM_004282) Human Untagged Clone

CAT#: SC303461

BAG2 (untagged)-Human BCL2-associated athanogene 2 (BAG2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BAG2
• Synonyms: BAG-2; dJ417I1.2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004282 edited
  GTGACCTCTTGGCTACCCCGCGTCGGAGGCTTAGATGGCTCAGGCGAAGATCAACGCTAA
  AGCCAACGAGGGGCGCTTCTGCCGCTCCTCCTCCATGGCTGACCGCTCCAGCCGCCTGCT
  GGAGAGCCTGGACCAGCTGGAGCTCAGGGTTGAAGCTTTGAGAGAAGCAGCAACTGCTGT
  TGAGCAAGAGAAAGAAATCCTTCTGGAAATGATCCACAGTATCCAAAATAGCCAGGACAT
  GAGGCAGATCAGTGACGGAGAAAGAGAAGAATTAAATCTGACTGCAAACCGTTTGATGGG
  AAGAACTCTCACCGTTGAAGTGTCAGTAGAAACAATTAGAAACCCCCAGCAGCAAGAATC
  CCTAAAGCATGCCACAAGGATTATTGATGAGGTGGTCAATAAGTTTCTGGATGATTTGGG
  AAATGCCAAGAGTCATTTAATGTCGCTCTACAGTGCATGTTCATCTGAGGTGCCACATGG
  GCCAGTTGATCAGAAGTTTCAATCCATAGTAATTGGCTGTGCTCTTGAAGATCAGAAGAA
  AATTAAGAGAAGATTAGAGACTCTGCTTAGAAATATTGAAAACTCTGACAAGGCCATCAA
  GCTATTAGAGCATTCTAAAGGAGCTGGTTCCAAAACTCTGCAACAAAATGCTGAAAGCAG
  ATTCAATTAGTCTTCAAACCTAAGAGCATTTACACAATACACAAGGTGTAAAAATGATAA
  AATACTATTTTAATTGATAACTAGTTCTTTGTTAGGTATAACCACTTAGTTGACACTGAT
  AGTTGTTTCAGATGAGGAAAATATTCCATCAAGTATCTTCAGTTTTGTGAATAACAAAAC
  TAGCAATATTTTAATTATCTATCTAGAGATTTTTTAGATTG
  
• Restriction Sites: Please inquire
• ACCN: NM_004282
• ORF Size: 636 bp
• Insert Size: 900
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_004282.2.

Reference Data

• RefSeq: NM_004282.2, NP_004273.1
• RefSeq Size: 1556
• RefSeq ORF: 636
• Locus ID: 9532
• Protein Families: Druggable Genome
• Gene Summary: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]