SPG48 (AP5Z1) (NM_014855) Human Untagged Clone

CAT#: SC304176

AP5Z1 (untagged)-Human KIAA0415 (KIAA0415)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AP5Z1
• Synonyms: KIAA0415; SPG48; zeta
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014855, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTCTCGGCAGGAGCGGAGAGTTTGCTCCACCAGGCCAGGGAGATCCAGGACGAGGAGCTGAAGAAGT
  TCTGTTCCCGGATCTGTAAACTGCTGCAGGCGGAGGACTTGGGGCCGGACACCCTCGACTCCCTGCAGAG
  GCTCTTCCTCATCATCTCAGCCACGAAGTACAGCCGGAGGCTGGAGAAGACATGCGTAGACCTGCTGCAG
  GCCACCCTCGGCCTGCCTGCATGCCCCGAGCAGCTCCAGGTGCTTTGCGCCGCCATCCTGCGAGAGATGT
  CCCCCTCTGACAGCCTCAGCCTGGCCTGGGACCACACGCAGAACAGCCGGCAGCTGAGCCTGGTGGCCTC
  CGTTCTCTTGGCCCAGGGTGACAGAAACGAGGAGGTCAGAGCCGTGGGCCAGGGCGTGCTACGAGCGCTG
  GAGAGCCGGCAGCCTGAGGGACCCAGCCTCAGACACCTCCTCCCCGTCATGGCCAAGGTCGTGGTCCTCA
  GCCCGGGCACCCTCCAGGAGGACCAGGCCACCCTGCTCAGCAAGCGGCTGGTCGACTGGCTGCGCTACGC
  CAGCCTCCAGCAAGGGCTCCCACACTCCGGCGGCTTCTTCTCCACGCCCAGGGCCCGGCAGCCGGGCCCC
  GTCACCGAGGTGGACGGGGCGGTAGCCACAGACTTCTTCACGGTGCTCTCCAGCGGCCACCGCTTCACAG
  ACGACCAGTGGCTGAACGTGCAGGCCTTCTCTATGCTGCGGGCGTGGCTGCTGCACAGCGGCCCCGAGGG
  CCCGGGCACCCTGGACACAGATGACAGGTCAGAGCAGGAGGGCTCCACTCTGTCGGTGATCTCCGCCACC
  TCCTCTGCCGGCCGCCTGCTGCCGCCCCGGGAGCGGCTTCGGGAGGTGGCCTTCGAGTACTGCCAGCGCC
  TCATTGAGCAAAGTAACCGACGAGCCCTGAGGAAGGGGGACTCCGACCTGCAGAAAGCTTGCCTGGTGGA
  GGCCGTGCTGGTGCTGGACGTGCTGTGCCGGCAGGACCCGTCCTTCCTGTACCGAAGTCTCTCCTGCCTG
  AAGGCCCTGCACGGGCGGGTGCGCGGGGACCCGGCCTCTGTGCGGGTGCTGCTGCCCCTCGCCCACTTCT
  TCCTGAGCCACGGGGAAGCGGCTGCAGTGGACTCGGAAGCCGTCTACCAGCACCTGTTCACCAGGATCCC
  GGTGGAGCAGTTCCACAGCCCCATGCTGGCCTTTGAATTCATCCAGTTCTGCAGGGACAACCTCCACCTG
  TTCAGCGGGCACCTCAGCACCCTCAGATTGAGCTTCCCCAACCTCTTTAAGTTCCTGGCCTGGAACAGCC
  CACCCCTCACCTCCGAGTTTGTGGCGCTCCTCCCGGCCCTGGTGGACGCTGGCACAGCCCTGGAGATGCT
  GCACGCGCTGCTGGACCTGCCCTGCTTGACGGCGGTGCTGGACCTGCAGCTCAGGTCAGCACCGGCTGCA
  TCCGAGAGGCCACTCTGGGACACCTCTCTCAGGGCCCCCAGCTGCCTGGAGGCCTTCCGGGACCCGCAGT
  TCCAGGGTCTTTTCCAATACCTGCTGCGCCCCAAGGCCAGTGGCGCCACTGAGAGGTTGGCGCCACTCCA
  CCAGCTGCTGCAGCCCATGGCCGGCTGTGCCCGCGTGGCCCAGTGTGCCCAGGCCGTGCCCACGCTGCTG
  CAGGCATTCTTCTCAGCAGTGACCCAGGTGGCTGACGGGTCCCTGATCAACCAGCTGGCGCTGCTGCTCC
  TGGGCAGGAGCGACTCGCTCTACCCGGCCCCAGGGTACGCTGCCGGTGTGCACAGTGTGCTGAGTTCTCA
  GTTCCTGGCCCTGTGTACGCTGAAACCCTCCCTGGTGGTGGAGCTGGCAAGAGACCTGCTGGAGTTCCTG
  GGCAGCGTGAATGGTCTCTGCAGCAGGGCGAGCCTCGTCACCAGCGTGGTGTGGGCCATCGGCGAGTACC
  TGTCGGTGACCTACGATCGGAGGTGCACCGTGGAGCAGATCAACAAGTTCTTCGAAGCCCTGGAGGCTCT
  GCTATTCGAGGTCACCCAGTGCCGCCCCTCTGCTGCCCTGCCCAGGTGTCCCCCCCAGGTGGTCACCGTG
  CTGATGACCACGCTGACGAAGCTGGCCTCCCGGAGCCAAGATCTGATCCCCAGGGCCTCTTTATTGCTGT
  CAAAGATGAGGACCCTGGCTCACAGTCCAGCCACCAGCTCCACGCACAGCGAGGAGGGCGCGGAAGCCAT
  CCGTACCCGGGCCACAGAGCTGCTGACCCTGCTGAAGATGCCTAGCGTGGCCCAGTTTGTGCTCACACCC
  AGCACGGAGGTGTGCAGCCCCCGCTATCACCGCGATGCCAACACGGCCCTGCCCCTGGCCCTGCGCACGG
  TCAGCCGGCTGGTGGAGAGGGAGGCCGGCCTCATGCCAGGGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_014855
• ORF Size: 2424 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014855.2, NP_055670.1
• RefSeq Size: 5519
• RefSeq ORF: 2424
• Locus ID: 9907
• Gene Summary: This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011]