Glycoprotein VI (GP6) (NM_016363) Human Untagged Clone

CAT#: SC304410

GP6 (untagged)-Human glycoprotein VI (platelet) (GP6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GP6
• Synonyms: BDPLT11; GPIV; GPVI
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016363 edited
  CAGGACAGGGCTGAGGAACCATGTCTCCATCCCCGACCGCCCTCTTCTGTCTTGGGCTGT
  GTCTGGGGCGTGTGCCAGCGCAGAGTGGACCGCTCCCCAAGCCCTCCCTCCAGGCTCTGC
  CCAGCTCCCTGGTGCCCCTGGAGAAGCCAGTGACCCTCCGGTGCCAGGGACCTCCGGGCG
  TGGACCTGTACCGCCTGGAGAAGCTGAGTTCCAGCAGGTACCAGGATCAGGCAGTCCTCT
  TCATCCCGGCCATGAAGAGAAGTCTGGCTGGACGCTACCGCTGCTCCTACCAGAACGGAA
  GCCTCTGGTCCCTGCCCAGCGACCAGCTGGAGCTCGTTGCCACGGGAGTTTTTGCCAAAC
  CCTCGCTCTCAGCCCAGCCCGGCCCGGCGGTGTCGTCAGGAGGGGACGTAACCCTACAGT
  GTCAGACTCGGTATGGCTTTGACCAATTTGCTCTGTACAAGGAAGGGGACCCTGCGCCCT
  ACAAGAATCCCGAGAGATGGTACCGGGCTAGTTTCCCCATCATCACGGTGACCGCCGCCC
  ACAGCGGAACCTACCGATGCTACAGCTTCTCCAGCAGGGACCCATACCTGTGGTCGGCCC
  CCAGCGACCCCCTGGAGCTTGTGGTCACAGGAACCTCTGTGACCCCCAGCCGGTTACCAA
  CAGAACCACCTTCCTCGGTAGCAGAATTCTCAGAAGCCACCGCTGAACTGACCGTCTCAT
  TCACAAACAAAGTCTTCACAACTGAGACTTCTAGGAGTATCACCACCAGTCCAAAGGAGT
  CAGACTCTCCAGCTGGTCCTGCCCGCCAGTACTACACCAAGGGCAACCTGGTCCGGATAT
  GCCTCGGGGCTGTGATCCTAATAATCCTGGCGGGGTTTCTGGCAGAGGACTGGCACAGCC
  GGAGGAAGCGCCTGCGGCACAGGGGCAGGGCTGTGCAGAGGCCGCTTCCGCCCCTGCCGC
  CCCTCCCGCAGACCCGGAAATCACACGGGGGTCAGGATGGAGGCCGACAGGATGTTCACA
  GCCGCGGGTTATGTTCATGACCGCTGAACCCCAGGCACGGTCGTATCCAAGGGAGGGATC
  ATGGCATGGGAGGCGACTCAAAGACTGGCGTGTGTGGAGCGTGGAAGCAGGAGGGCAGAG
  GCTACAGCTGTGGAAACGAGGCCATGCTGCCTCCTCCTGGTGTTCCATCAGGGAGCCGTT
  CGGCCAGTGTCTGTCTGTCTGTCTGCCTCTCTGTCTGAGGGCACCCTCCATTTGGGATGG
  AAGGAATCTGTGGAGACCCCATCCTCCTCCCT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016363 unedited
  GTTCGGAATTTGTATACGACTCATATAGGGCGGCCGCGATTCGCCCTTCAGNACAGGCTG
  AGGAACCATGTCTCCATCCCCGACCGCCCTCTTCTGTCTTGGGCTGTGTCTGGGGCGTGT
  GCCAGCGCAGAGTGGACCGCTCCCCAAGCCCTCCCTCCAGGCTCTGCCCAGCTCCCTGGT
  GCCCCTGGAGAAGCCAGTGACCCTCCGGTGCCAGGGACCTCCGGGCGTGGACCTGTACCG
  CCTGGAGAAGCTGAGTTCCAGCAGGTACCAGGATCAGGCAGTCCTCTTCATCCCGGCCAT
  GAAGAGAAGTCTGGCTGGACGCTACCGCTGCTCCTACCAGAACGGAAGCCTCTGGTCCCT
  GCCCAGCGACCAGCTGGAGCTCGTTGCCACGGGAGTTTTTGCCAAACCCTCGCTCTCAGC
  CCAGCCCGGCCCGGCGGTGTCGTCAGGAGGGGACGTAACCCTACAGTGTCAGACTCGGTA
  TGGCTTTGACCAATTTGCTCTGTACAAGGAAGGGGACCCTGCGCCCTACAAGAATCCCGA
  GAGATGGTACCGGGCTAGTTTCCCCATCATCACGGTGACCGCCGCCCACAGCGGAACCTA
  CCGATGCTACAGCTTCTCCAGCAGGGACCCATACCTGTGGTCGGCCCCCAGCGACCCCCT
  GGAGCTTGTGGTCACAGGAACCTCTGTGACCCCCAGCCGGTTACCAACAGAACCACCTTC
  CTCGGTAGCAGAATTCTCAGAAGCCACCGCTGAACTGACCGTCTCATTCACAAACAAAGT
  CTTCACAACTGAGACTTCTAGGAGTATCACCACCAGTCCAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_016363
• ORF Size: 1020 bp
• Insert Size: 1300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_016363.3, NP_057447.3
• RefSeq Size: 2263
• RefSeq ORF: 1020
• Locus ID: 51206
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ECM-receptor interaction
• Gene Summary: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a frameshift. It encodes isoform 2 which has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.