Spectrin beta chain, brain 3 (SPTBN4) (NM_020971) Human Untagged Clone

CAT#: SC304879

SPTBN4 (untagged)-Human spectrin, beta, non-erythrocytic 4 (SPTBN4), transcript variant sigma1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPTBN4
• Synonyms: CMND; NEDHND; QV; SPNB4; SPTBN3
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_020971, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGCAGGTACCAGGGGAAGTGGACAACATGGAGGGCCTGCCTGCTCCTAACAACAACCCTGCTGCCC
  GCTGGGAGAGTCCGGATCGGGGCTGGGAGCGGGAGCAGCCGGCTGCGTCCACCGCAGCGGCCTCGCTCTT
  TGAGTGCTCCCGGATCAAGGCCTTGGCAGATGAGCGGGAAGCCGTGCAGAAGAAAACCTTCACCAAGTGG
  GTGAACTCGCACCTCGCCCGCGTGGGCTGCCACATCGGGGACCTCTATGTGGACCTCCGGGACGGCTTCG
  TGCTCACGCGGCTCCTGGAAGTGCTGTCTGGGGAGCAGCTGCCCAGGCCCACGCGCGGCCGCATGCGGAT
  CCACTCACTGGAGAACGTGGACAAGGCGCTGCAGTTTCTGAAGGAGCAGCGCGTGCACCTGGAGAACGTG
  GGTTCGCATGACATCGTGGATGGGAATCACCGGCTGACGCTGGGGCTGGTCTGGACCATCATCCTGCGCT
  TCCAGATTCAAGTCATCAAAATTGAGACTGAGGACAACAGAGAGACACGCTCAGCCAAGGATGCTCTGCT
  CTTGTGGTGTCAGATGAAGACAGCTGGTTACCCTGAGGTAAACATCCAGAATTTCACCACCAGCTGGCGG
  GATGGCTTGGCCTTCAATGCCCTCATTCACCGGCACAGGCCTGATCTCGTGGACTTCAGCAAACTCACCA
  AGTCCAATGCCAACTACAACCTGCAGAGAGCCTTCCGCACAGCTGAGCAGCACCTGGGGCTGGCGCGGCT
  GCTGGATCCTGAAGATGTGAACATGGAGGCTCCAGATGAGAAGTCCATCATCACCTACGTGGTCTCTTTC
  TACCACTATTTCTCCAAGATGAAGGCTCTGGCTGTGGAGGGGAAGCGTATCGGGAAGGTCTTGGACCAGG
  TATTGGAGGTGGGGAAGATCATAGAACGCTACGAGGAGCTGGCGGCTGAGCTGCTGGCCTGGATCCACCG
  CACCGTGGGCCTCATCAGCAATCAGAAATTTGCCAACTCCTTAAGTGGGGTGCAGCAGCAACTCCAGGCT
  TTCACGGCCTATTGCACGCTGGAGAAGCCTGTCAAGTTCCAGGAGAAGGGGAACCTAGAGGTGCTGCTCT
  TCAGCATCCAGAGCAAACTGCGTGCCTGCAACCGTCGCCTCTTTGTGCCTCGGGAGGGCTGTGGCATCTG
  GGATATTGACAAGGCATGGGGTGAGCTGGAGAAGGCTGAGCATGAGCGGGAGGCTGCCCTACGGGCTGAG
  CTGATTCGGCAGGAGAAGCTGGAACTACTGGCACAGAGGTTTGACCACAAGGTGGCTATGAGGGAGAGCT
  GGCTGAATGAGAACCAGCGTCTGGTCTCCCAGGACAACTTTGGGTATGAGCTGCCCGCAGTGGAGGCAGC
  CATGAAGAAACACGAAGCGATCGAGGCAGACATTGCGGCCTACGAGGAGCGGGTGCAGGGTGTGGCGGAG
  CTGGCCCAGGCATTGGCAGCCGAAGGCTACTACGATATCCGGCGGGTGGCAGCCCAGCGTGACAGCGTCC
  TGCGCCAGTGGGCCCTGCTAACTGGGCTTGTGGGTGCCCGGCGGACACGACTTGAGCAGAACCTTGCCCT
  GCAGAAGGTCTTCCAGGAGATGGTGTACATGGTGGACTGGATGGAGGAGATGCAGGCTCAGCTGCTGTCC
  CGGGAGTGTGGGCAGCACCTGGTGGAGGCAGACGACCTGTTGCAGAAGCATGGACTGCTGGAGGGAGACA
  TTGCCGCCCAGAGCGAGCGGGTGGAGGCTCTCAATGCCGCTGCCCTGCGCTTCTCCCAGCTGCAGGGCTA
  CCAGCCCTGCGACCCGCAGGTCATCTGCAACCGCGTGAACCACGTGCACGGCTGCCTGGCGGAGCTGCAG
  GAGCAGGCAGCGCGGCGACGCGCGGAGCTGGAGGCTTCGCGGAGCCTGTGGGCGCTGCTGCAGGAGCTGG
  AGGAGGCCGAGAGCTGGGCGCGCGACAAGGAGCGTCTCCTGGAGGCTGCGGGCGGCGGCGGTGCGGCGGG
  CGCAGCGGGCGCAGCGGGAACAGCGGGCGGCGCGCATGACCTGTCCAGCACAGCGCGCCTCCTGGCCCAG
  CACAAGATCCTGCAGGGCGAGCTGGGCGGGCGGCGAGCGTTGCTGCAGCAGGCCCTGCGGTGTGGCGAGG
  AGCTGGTTGCGGCCGGCGGTGCCGTCGGCCCGGGAGCAGACACCGTGCACCTGGTAGGCCTGGCGGAGCG
  CGCGGCGAGCGCCCGGCGCCGCTGGCAGAGGCTGGAAGAGGCGGCGGCGCGGCGAGAGCGGCGGCTGCAG
  GAGGCGCGGGCGCTGCACCAGTTCGGCGCTGACCTCGACGGGCTGCTGGACTGGCTTCGCGACGCTTACC
  GCCTGGCAGCCGCCGGTGACTTCGGCCACGACGAAGCTTCCAGCCGCCGCCTGGCGCGCCAGCACCGCGC
  GCTCACCGGGGAGGTGGAGGCACATCGCGGGCCCGTGAGCGGCCTGCGGCGCCAGCTGGCGACACTCGGG
  GGTGCCAGTGGCGCAGGGCCACTGGTGGTGGCGCTGCAGGTGCGCGTGGTGGAAGCAGAGCAGTTGTTCG
  CTGAGGTGACCGAAGTGGCGGCGCTGAGGCGCCAGTGGCTGCGGGACGCGCTCGCTGTCTACCGCATGTT
  TGGCGAGGTGCACGCGTGTGAGCTGTGGATCGGCGAGAAGGAGCAATGGCTGCTCTCCATGCGTGTGCCG
  GATTCACTCGACGACGTCGAGGTGGTGCAGCACCGATTCGAGAGCCTGGACCAAGAGATGAACAGCCTGA
  TGGGCCGCGTTCTGGACGTGAACCACACAGTCCAGGAGCTGGTGGAAGGAGGCCACCCCAGTTCAGATGA
  GGTGCGTTCCTGCCAGGACCACCTCAACAGCAGGTGGAACCGCATCGTGGAGCTAGTGGAACAGCGCAAA
  GAGGAAATGAGCGCGGTGCTGCTGGTGGAGAACCACGTGCTGGAGGTGGCCGAGGTGCGCGCCCAGGTGC
  GTGAGAAGCGGAGAGCTGTGGAGAGCGCGCCCCGGGCCGGCGGCGCCCTGCAGTGGCGTCTTAGCGGCCT
  AGAGGCCGCTCTGCAGGCGCTGGAGCCGCGCCAGGCGGCCCTTCTGGAGGAGGCAGCCCTGCTGGCTGAG
  CGCTTCCCGGCGCAGGCGGCGCGGCTGCACCAGGGCGCGGAGGAGCTGGGCGCCGAGTGGGGCGCGCTAG
  CTAGCGCGGCTCAGGCCTGCGGCGAGGCGGTGGCGGCAGCAGGGCGCCTGCAGCGCTTCCTACATGACCT
  CGACGCTTTCCTGGACTGGCTCGTGCGCGCCCAGGAGGCGGCGGGCGGCAGCGAGGGGCCCCTGCCCAAC
  AGCCTAGAAGAGGCGGACGCGCTGCTGGCGCGCCACGCTGCGCTCAAGGAGGAGGTGGACCAGCGCGAGG
  AAGACTATGCTCGCATCGTGGCGGCCAGCGAGGCGCTGCTGGCCGCCGACGGCGCAGAGCTGGGCCCGGG
  CCTGGCACTAGACGAGTGGCTGCCACACCTCGAACTTGGCTGGCATAAACTGCTCGGCTTGTGGGAGGCG
  CGCAGGGAGGCGCTGGTCCAGGCGCACATCTACCAGCTCTTCCTGCGGGATCTACGCCAGGCGCTCGTGG
  TGCTGCGTAACCAGGAGATGGCGCTGTCTGGTGCGGAGCTCCCGGGCACAGTGGAATCGGTGGAGGAGGC
  CTTGAAACAGCACCGTGACTTTCTCACCACCATGGAGCTGAGCCAGCAAAAGATGCAGGTGGCCGTGCAG
  GCTGCAGAGGGCCTGCTGAGGCAGGGCAACATCTACGGGGAGCAGGCTCAGGAGGCTGTGACCCGGCTGC
  TGGAGAAGAACCAAGAAAACCAGTTACGGGCCCAGCAATGGATGCAAAAGCTACATGACCAACTTGAGCT
  GCAGCACTTCCTCCGAGACTGCCACGAGCTGGATGGCTGGATCCATGAGAAGATGCTGATGGCGCGGGAT
  GGCACGCGGGAGGACAACCACAAGCTGCATAAGAGATGGCTCCGGCACCAGGCATTCATGGCCGAGCTGG
  CTCAGAATAAGGAGTGGCTGGAGAAGATCGAGCGGGAGGGCCAGCAACTGATGCAGGAGAAGCCCGAACT
  GGCGGCCTCCGTGCGGAAGAAGCTGGGCGAGATCCGCCAGTGCTGGGCGGAGCTGGAGAGCACCACCCAG
  GCCAAGGCACGGCAGCTCTTTGAGGCCAGCAAAGCAGACCAGCTGGTGCAGAGCTTTGCTGAGCTGGACA
  AGAAGCTCCTTCACATGGAGAGCCAGCTGCAAGACGTGGACCCTGGAGGAGACCTGGCCACTGTCAACAG
  TCAGCTCAAGAAGCTGCAGTCCATGGAGTCGCAGGTGGAGGAGTGGTACCGCGAGGTGGGAGAGCTGCAG
  GCGCAGACGGCGGCGCTGCCGCTGGAGCCGGCGAGCAAGGAGCTGGTGGGTGAGCGGCAGAACGCGGTGG
  GCGAGCGCCTGGTGCGCCTGCTCGAGCCGTTGCAGGAGCGCCGCCGCTTGCTGCTGGCTTCCAAGGAGTT
  GCACCAGGTGGCGCACGACCTGGACGACGAGCTGGCATGGGTTCAGGAGCGGCTGCCACTGGCCATGCAG
  ACAGAGCGAGGCAACGGTTTGCAGGCGGTCCAGCAGCACATCAAAAAGAACCAGGGCCTGCGGCGGGAGA
  TCCAGGCGCATGGGCCGCGCCTGGAGGAGGTGCTGGAGCGCGCGGGCGCGCTGGCGTCGCTGCGCAGCCC
  GGAGGCAGAGGCAGTGCGCCGGGGCCTGGAGCAGCTGCAGAGCGCCTGGGCCGGACTGCGGGAGGCTGCC
  GAGCGACGGCAGCAGGTGCTGGACGCCGCCTTCCAGGTGGAGCAGTACTACTTCGACGTGGCTGAGGTGG
  AGGCGTGGCTGGGCGAGCAGGAGCTGCTCATGATGAGTGAGGACAAGGGCAAGGACGAACAGAGCACCCT
  GCAGCTGCTCAAGAAACACCTGCAGCTGGAGCAAGGCGTGGAGAACTACGAGGAAAGCATCGCGCAGCTG
  TCGCGCCAGTGCCGGGCGCTGCTGGAGATGGGGCACCCGGACAGCGAGCAGATCAGCCGGCGGCAGTCTC
  AGGTGGACCGCCTGTACGTGGCGCTCAAGGAGCTGGGTGAGGAGCGCCGGGTGGCTCTGGAACAGCAGTA
  CTGGCTGTACCAGCTCAGCCGCCAGGTGAGCGAGCTTGAGCACTGGATTGCCGAGAAGGAGGTGGTGGCT
  GGCTCACCCGAGCTCGGCCAGGACTTTGAGCATGTCTCGGTGCTGCAGGAGAAATTCTCAGAGTTTGCCA
  GCGAGACAGGTATGGCAGGGCGGGAACGGCTGGCAGCTGTGAACCAGATGGTGGATGAGCTGATCGAGTG
  TGGCCATACAGCAGCGGCCACCATGGCCGAGTGGAAGGACGGACTGAACGAGGCCTGGGCTGAGCTGCTG
  GAGCTCATGGGCACACGGGCCCAGCTGCTGGCCGCCTCTCGGGAGCTTCATAAGTTCTTCAGTGACGCCC
  GAGAGCTTCAGGGACAGATTGAGGAGAAGCGGAGGCGGCTGCCCCGCCTGACCACCCCGCCTGAGCCGAG
  ACCCAGTGCCAGTTCCATGCAGCGGACCCTGAGAGCCTTTGAGCATGACCTGCAGCTCCTCGTGTCCCAG
  GTACGGCAGCTGCAGGAGGGGGCGGCCCAGCTGCGGACGGTGTATGCGGGTGAACATGCCGAGGCCATCG
  CTAGCCGGGAGCAGGAGGTGCTGCAGGGTTGGAAAGAGCTGCTGTCAGCCTGTGAGGATGCCCGCCTGCA
  TGTCAGCTCCACAGCCGACGCCCTGCGCTTCCACAGCCAAGTCCGCGACCTGCTCTCCTGGATGGATGGC
  ATCGCCAGCCAGATTGGGGCAGCCGACAAGCCCAGGGACGTGTCATCAGTGGAGGTGCTCATGAACTACC
  ACCAGGGCCTGAAGACTGAGCTGGAGGCGCGGGTGCCTGAGCTGACCACCTGCCAGGAGCTGGGGCGATC
  TCTGCTGCTCAACAAAAGTGCCATGGCTGATGAGATCCAGGCACAGCTGGACAAGCTGGGAACCAGGAAG
  GAGGAGGTGTCGGAAAAGTGGGACCGCCATTGGGAGTGGCTGCAGCAGATGCTGGAGGTGCACCAGTTTG
  CCCAGGAGGCGGTGGTGGCTGATGCCTGGCTGACAGCCCAGGAGCCGCTCCTGCAGAGCCGGGAGCTGGG
  CAGCAGCGTGGATGAGGTGGAGCAGCTTATCCGGCGACATGAGGCCTTCCGCAAAGCGGCTGCAGCCTGG
  GAAGAGAGGTTCAGCTCTCTGCGGCGCCTGACCACGATCGAGAAAATCAAAGCGGAACAGAGCAAGCAGC
  CGCCTACCCCACTGCTGGGGCGCAAGTTCTTTGGGGACCCCACGGAACTGGCGGCCAAGGCGGCGCCCCT
  GCTGCGGCCAGGGGGCTATGAAAGGGGCTTGGAGCCCCTGGCCCGCCGAGCCTCGGACACGCTCTCGGCC
  GAGGTGCGGACTCGGGTGGGGTATGTGCGCCAGGAGCTCAAGCCCGAGCGCCTCCAGCCGCGCATTGACC
  GGCTGCCGGAGATCCCGGGGAGGGTGGAGCCCGCGGCCCTGCCGGCCGCACCAGAGGACGCGGCGGAGAC
  CCCCGCGACCCCCGCGGCGGCGGAGCAGGTGCGGCCACGACCGGAGCGCCAGGAGTCAGCTGATCGCGCG
  GAGGAGCTGCCCAGGAGGCGGCGGCCTGAGCGGCAAGAGTCAGTCGATCAATCCGAGGAGGCTGCGCGGA
  GGCGGCGGCCGGAGCGGCAGGAGTCAGCGGAGCACGAGGCGGCACACAGCCTTACCCTGGGCCGCTATGA
  GCAGATGGAGCGGCGGCGCGAGCGGCGTGAGCGGCGCTTGGAGCGGCAGGAGTCCAGCGAACAGGAGATG
  CCCATCAGAGGAGACCTGGTCAAGGGGAAGGCCACCCTGGCTGACATTGTGGAACAGCTGCAGGAGAAAG
  AGGCAGGCCCAGGGCTGCCTGCTGGGCCGTCGCTGCCTCAGCCACGCGAGCTTCCCCCAGGTCGCCTGCC
  CAACGGGCTTGAGCTGCCCGAGCGGACACCTCGGCCGGACCGGCCCCGGGCGCGGGACCGGCCCAAGCCG
  CGACGGCGGCCGCGGCCCAGAGAGGGTGGTGAGGGCGGGGGAAGCCGGCGCTCGCGCTCCGCCCCGGCCC
  AGGGCGGCTCCGCCCCCGCGCCTCCGCCACCGCCCACTCACACAGTGCAGCACGAGGGCTTCCTACTGCG
  CAAGCGCGAGCTCGACGCTAACCGCAAGTCGTCCAACCGGTCGTGGGTGAGCCTGTACTGTGTGCTTAGT
  AAGGGGGAACTGGGCTTCTACAAGGACTCCAAGGGCCCGGCATCCGGGAGCACACACGGTGGGGAACCGC
  TGCTCAGCCTGCACAAGGCCACCAGCGAGGTGGCTAGTGACTACAAGAAAAAGAAGCATGTCTTCAAGCT
  CCAGACCCAGGATGGCAGTGAGTTTTTGCTCCAGGCAAAAGATGAGGAGGAGATGAACGGCTGGCTGGAG
  GCTGTAGCTTCCTCGGTGGCGGAACACGCAGAGATCGCCCGCTGGGGCCAGACACTACCCACTACTTCAT
  CCACAGATGAGGGCAACCCTAAGAGGGAAGGCGGAGATCGCAGGGCCAGCGGGCGCAGGAAGTGA
  
  
• Restriction Sites: Please inquire
• ACCN: NM_020971
• ORF Size: 7695 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020971.1, NP_066022.1
• RefSeq Size: 8671
• RefSeq ORF: 7695
• Locus ID: 57731
• Gene Summary: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (sigma1) represents the longer transcript and encodes the longer isoform (sigma1), also known as the 289 kDa isoform.