B3GALT1 (NM_020981) Human Untagged Clone

CAT#: SC304882

B3GALT1 (untagged)-Human UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 (B3GALT1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: B3GALT1
• Synonyms: beta3Gal-T1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_020981, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTTCAAAGGTCTCCTGTTTGTATGTTTTGACAGTTGTGTGCTGGGCCAGCGCTCTCTGGTACTTGA
  GTATAACTCGCCCTACTTCTTCTTACACTGGCTCCAAACCATTCAGCCACCTAACAGTTGCCAGGAAAAA
  CTTCACCTTTGGCAACATAAGAACTCGACCTATCAACCCACATTCTTTTGAATTTCTTATCAACGAGCCC
  AATAAATGTGAGAAAAACATTCCTTTTCTTGTTATCCTCATCAGCACCACTCACAAGGAATTTGATGCCC
  GTCAGGCAATCAGAGAGACGTGGGGGGATGAGAACAACTTTAAGGGGATCAAGATAGCCACCCTGTTCCT
  CCTGGGCAAGAATGCTGATCCTGTTCTCAATCAGATGGTGGAGCAAGAGAGCCAAATCTTCCATGATATC
  ATCGTGGAGGACTTTATTGACTCCTACCATAACCTTACCCTCAAAACATTAATGGGGATGAGATGGGTGG
  CCACTTTTTGTTCAAAAGCCAAGTATGTCATGAAAACAGACAGCGACATTTTTGTAAACATGGACAATCT
  TATTTATAAATTACTGAAACCCTCCACCAAGCCACGAAGAAGGTATTTTACTGGCTATGTCATTAATGGA
  GGACCGATTCGGGATGTCCGCAGTAAGTGGTATATGCCCAGGGATTTGTACCCAGACAGTAACTACCCAC
  CTTTCTGTTCGGGGACTGGCTACATCTTTTCAGCCGATGTAGCTGAACTCATTTACAAGACCTCACTCCA
  CACAAGGCTGCTTCACCTTGAAGACGTATATGTGGGACTGTGTCTTCGAAAGCTGGGCATACATCCTTTC
  CAGAACAGTGGCTTCAATCACTGGAAAATGGCCTACAGTTTGTGTAGGTATCGCCGAGTTATCACTGTGC
  ATCAGATCTCTCCAGAAGAAATGCACAGAATCTGGAATGACATGTCAAGCAAGAAACATCTCAGATGTTA
  G
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_020981
• ORF Size: 981 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020981.3, NP_066191.1
• RefSeq Size: 2168
• RefSeq ORF: 981
• Locus ID: 8708
• Protein Families: Transmembrane
• Protein Pathways: Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways
• Gene Summary: This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is expressed exclusively in the brain. The encoded protein shows strict donor substrate specificity for UDP-galactose. [provided by RefSeq, Jul 2008]