DDHD1 (NM_030637) Human Untagged Clone

CAT#: SC305276

DDHD1 (untagged)-Human DDHD domain containing 1 (DDHD1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DDHD1
• Synonyms: PA-PLA1; PAPLA1; SPG28
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_030637 edited
  GTTGAATGTGTGGCGGAAGCGCTGGGGGTCACGGCTCCGCGCGCCGCCGGACAGCCGGCG
  GCGTCTCCACAGCATGAATTACCCGGGCCGCGGGTCCCCACGGAGCCCCGAGCATAACGG
  CCGAGGCGGCGGCGGCGGCGCCTGGGAGCTGGGCTCAGACGCGAGGCCAGCGTTCGGCGG
  CGGCGTCTGCTGCTTCGAGCACCTGCCCGGCGGGGACCCGGACGACGGCGACGTGCCCCT
  GGCCCTGCTGCGCGGGGAACCCGGGCTGCATTTGGCGCCGGGCACCGACGACCACAACCA
  CCACCTCGCGCTGGACCCCTGCCTCAGTGACGAGAACTATGACTTTAGCTCCGCCGAGTC
  GGGCTCCTCGCTGCGCTACTACAGCGAGGGTGAGAGCGGCGGCGGCGGCGGCGGCAGCTC
  CTTGTCGCTGCATCCGCCGCAGCAGCCTCCGCTGGTCCCGACGAACTCGGGGGGCGGCGG
  CGCGACAGGAGGGTCCCCCGGGGAAAGGAAACGTACCCGGCTTGGCGGCCCGGCGGCCCG
  GCACCGCTATGAGGTAGTGACGGAGCTGGGCCCGGAGGAGGTACGCTGGTTCTACAAGGA
  GGACAAGAAGACCTGGAAGCCCTTCATCGGCTACGACTCGCTCCGCATCGAGCTCGCCTT
  CCGGACCCTGCTGCAGACCACGGGTGCCCGGCCCCAGGGCGGGGACCGGGACGGCGACCA
  TGTGTGCTCCCCCACGGGCCCAGCCTCCAGTTCCGGAGAAGATGACGATGAGGACCGCGC
  CTGCGGCTTCTGCCAGAGTACGACGGGGCACGAGCCGGAGATGGTGGAGCTTGTGAACAT
  CGAGCCTGTGTGCGTGCGGGGCGGCCTCTACGAGGTGGATGTGACCCAAGGAGAGTGCTA
  CCCGGTGTACTGGAACCAGGCTGATAAAATACCAGTAATGCGTGGACAGTGGTTTATTGA
  CGGCACTTGGCAGCCTCTAGAAGAGGAAGAAAGTAATTTAATTGAGCAAGAACATCTCAA
  TTGTTTTAGGGGCCAGCAGATGCAGGAAAATTTCGATATTGAAGTGTCAAAATCCATAGA
  TGGAAAAGATGCTGTTCATAGTTTCAAGTTGAGTCGAAACCATGTGGACTGGCACAGTGT
  GGATGAAGTATATCTTTATAGTGATGCAACAACATCTAAAATTGCAAGAACAGTTACCCA
  AAAACTGGGATTTTCTAAAGCATCAAGTAGTGGTACCAGACTTCATAGAGGTTATGTAGA
  AGAAGCCACATTAGAAGACAAGCCATCACAGACTACCCATATTGTATTTGTTGTGCATGG
  CATTGGGCAGAAAATGGACCAAGGAAGAATTATCAAAAATACAGCTATGATGAGAGAAGC
  TGCAAGAAAAATAGAAGAAAGGCATTTTTCCAACCATGCAACACATGTTGAATTTCTGCC
  TGTTGAGTGGCGGTCAAAACTTACTCTTGATGGAGACACTGTTGATTCCATTACTCCTGA
  CAAAGTACGAGGTTTAAGGGATATGCTGAACAGCAGTGCAATGGACATAATGTATTATAC
  TAGTCCACTTTATAGAGATGAACTAGTTAAAGGCCTTCAGCAAGAGCTGAATCGATTGTA
  TTCCCTTTTCTGTTCTCGGAATCCAGACTTTGAAGAAAAAGGGGGTAAAGTCTCAATAGT
  ATCACATTCCTTGGGATGTGTAATTACTTATGACATAATGACTGGCTGGAATCCAGTTCG
  GCTGTATGAACAGTTGCTGCAAAAGGAAGAAGAGTTGCCTGATGAACGATGGATGAGCTA
  TGAAGAACGACATCTTCTTGATGAACTCTATATAACAAAACGACGGCTGAAGGAAATAGA
  AGAACGGCTTCACGGATTGAAAGCATCATCTATGACACAAACACCTGCCTTAAAATTTAA
  GGTTGAGAATTTCTTCTGTATGGGATCCCCATTAGCAGTTTTCTTGGCGTTGCGTGGCAT
  CCGCCCAGGAAATACTGGAAGTCAAGACCATATTTTGCCTAGAGAGATTTGTAACCGGTT
  ACTAAATATTTTTCATCCTACAGATCCAGTGGCTTATAGATTAGAACCATTAATACTGAA
  ACACTACAGCAACATTTCACCTGTCCAGATCCACTGGTACAATACTTCAAATCCTTTACC
  TTATGAACATATGAAGCCAAGCTTTCTCAACCCAGCTAAAGAACCTACCTCAGTTTCAGA
  GAATGAAGGCATTTCAACCATACCAAGCCCTGTGACCTCACCAGTTTTGTCCCGCCGACA
  CTATGGAGAATCTATAACAAATATAGGCAAAGCAAGCATATTAGGGGCTGCTAGCATTGG
  AAAGGGACTTGGAGGAATGTTGTTCTCAAGATTTGGACGTTCATCTACAACACAGTCATC
  TGAAACATCAAAAGACTCAATGGAAGATGAGAAGAAGCCAGTTGCCTCACCTTCTGCTAC
  CACCGTAGGGACACAGACCCTTCCACATAGCAGTTCTGGCTTCCTCGATTCTGCATTGGA
  GTTGGATCACAGGATTGATTTTGAACTCAGAGAAGGCCTTGTGGAGAGCCGCTATTGGTC
  AGCTGTCACGTCGCATACTGCCTATTGGTCATCCTTGGATGTTGCCCTTTTTCTTTTAAC
  CTTCATGTATAAACATGAGCACGATGATGATGCAAAACCCAATTTAGATCCAATCTGAAC
  TCTTGAAGGACATGAATGGCCTAAAACTGATTTTTTTTTTTTCCGTTAAAATGTGTGTGT
  CAAGATACGGAGATTTCAGGGTTAAAGTATATTTCAGTTTTCTTTAGGGCAACATATATT
  TGAATTTAAAAGCACTTTATTTAAAAAAAAAAGAAGTTTTCAGTTCTGAAGAAGTCATTT
  ACAGTTTGCATCATTTTAATTATGAGTCTGACAAAACCTTCTCCAGAGAATCAAGCAAGA
  CCTGGATGTGAAGAAGGTTTGGGTAAACTGCATGTAAAGGCTACAAATCACAATCTGATT
  CCTCCCAAATATAAAGGCATATGGAACATAATGTATTAACCAAAGTATGTTATAAATCAA
  AAATGGTCAAGGTTCAGCATATTCTATATGAAGATCACAAGGTGGTATCGTTTTAGATTT
  CTATGAAGGCTTTCATTTGTACATCCCTTTGAAAAAATATAACAGATTTAAAATGTTTTG
  AATTTAACTTGTTTAGAAAAACTAATGCTTAAAACAATATTTGAACTACTGTATTTATAA
  TTTATTACCTCTAATTGCTTTATTTCAGTGTATGAGACATTACTGTTTTAATGTTTGCTT
  TGAACATAATTTAAGAACCAGATTTATTTTCTATAGTGATAAACCCTTTTTTCTCAGAAC
  TCCATCTTTGTACTCTTCAGATGAATATATAGACACTGTGGCATACATTTTTTTTCATTA
  AAAACTTATGGCTTCATACAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_030637 unedited
  CATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGGTTGAATGTGTGGCG
  GAAGCGCTGGGGGTCACGGCTCCGCGCGCCGCCGGACAGCCGGCGGCGTCTCCACAGCAT
  GAATTACCCGGGCCGCGGGTCCCCACGGAGCCCCGAGCATAACGGCCGAGGCGGCGGCGG
  CGGCGCCTGGGAGCTGGGCTCAGACGCGAGGCCAGCGTTCGGCGGCGGCGTCTGCTGCTT
  CGAGCACCTGCCCGGCGGGGACCCGGACGACGGCGACGTGCCCCTGGCCCTGCTGCGCGG
  GGAACCCGGGCTGCATTTGGCGCCGGGCACCGACGACCACAACCACCACCTCGCGCTGGA
  CCCCTGCCTCAGTGACGAGAACTATGACTTTAGCTCCGCCGAGTCGGGCTCCTCGCTGCG
  CTACTACAGCGAGGGTGAGAGCGGCGGCGGCGGCGGCGGCAGCTCCTTGTCGCTGCATCC
  GCCGCAGCAGCCTCCGCTGGTCCCGACGAACTCGGGGGGCGGCGGCGCGACAGGAGGGTC
  CCCCGGGGAAAGGAAACGTACCCGGCTTGGCGGCCCGGCGGCCCGGCACCGCTATGAGGT
  AGTGACGGAGCTGGGCCCGGAGGAGGTACGCTGGTTCTACAAGGAGGACAAGAAGACCTG
  GAAGCCCTTCATCGGCTACGACTCGCTCCGCATCGAGCTCGCCTTCCGGACCCTGCTGCA
  GACCACGGGTGCCCGGCCCCAGGGCGGNGACCGGGACGGCGACCATGTGTGCTCCCCCAC
  GGGCCCAGCCTNCAGTCCGGAGAAGAGACGATGAGGACCGCGCCTNGGCGCTCTGCCAGA
  GTACGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_030637 unedited
  CCCCGAGTCAATGAATATGAAAAAAAGTATGCCCAGGGAAAATATTTTCTCTGAGAGTAC
  CAAGAGGGAGTTCTGAGAAAAAAGGGTTTATCACTATAGAAAATAAATCTGGTTCTTAAA
  TTATGTTCAAAGCAAACATTAAAACAGTAATGTCTCATACTCTGAAATAAAGCAATTAGA
  GGTAATAAATTATAAATACAGTAGTTCAAATATTGTTTTAAGCATTAGTTTTTCTAAACA
  AGTTAAATTCAAAACATTTTAAATCTGTTATATTTTTTCAAAGGGATGTACAAATGAAAG
  CCTTCATAGAAATCTAAAACGATACCACCTTGTGATCTTCATATAGAATATGCTGAACCT
  TGACCATTTTTGATTTATAACATACTTTGGTTAATACATTATGTTCCATATGCCTTTATA
  TTTGGGAGGAATCAAATTGTGATTTGTAGCCTTTACATGCAGTTTACCCAAACCTTCTTA
  ACATCCAGGTCTTGCTTGATACTCTGGAGAAGGTTTTGTCCAACTCATAATTAAAATGAT
  GCCAACTGTAAATGACTTCTTCATAACTGAAAACTTCTTTTTTTTTTTAAATAAAATGCT
  TTTAAATTCACATATATGTTGCCCTCAACAAAACTGAAATATACTTTAAGACCTGAAATC
  TTCGTACTTGAAACACACATTTTAACCGGAAAAAAAAAAAATAACTTCTAGGCCTTTCCT
  GTCCCTCAATAGACGAGAATGTATATAAATTGGGTTTTTCAATAAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_030637
• ORF Size: 2619 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by two amino acids.

Reference Data

• RefSeq: NM_030637.1, NP_085140.1
• RefSeq Size: 3563
• RefSeq ORF: 2619
• Locus ID: 80821
• Gene Summary: This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
  Transcript Variant: This variant (1) represents the shortest transcript and encodes the shortest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.