MADCAM1 (NM_130762) Human Untagged Clone

CAT#: SC305896

MADCAM1 (untagged)-Human mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MADCAM1
• Synonyms: MACAM1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_130762 edited
  GGCGGCCGCGAATTCATGGATTTCGGACTGGCCCTCCTGCTGGCGGGGCTTCTGGGGCTC
  CTCCTCGGCCAGTCCCTCCAGGTGAAGCCCCTGCAGGTGGAGCCCCCGGAGCCGGTGGTG
  GCCGTGGCCTTGGGCGCCTCGCGCCAGCTCACCTGCCGCCTGGCCTGCGCGGACCGCGGG
  GCCTCGGTGCAGTGGCGGGGCCTGGACACCAGCCTGGGCGCGGTGCAGTCGGACACGGGC
  CGCAGCGTCCTCACCGTGCGCAACGCCTCGCTGTCGGCGGCCGGGACCCGCGTGTGCGTG
  GGCTCCTGCGGGGGCCGCACCTTCCAGCACACCGTGCAGCTCCTTGTGTACGCCTTCCCG
  GACCAGCTGACCGTCTCCCCGGCAGCCCTGGTGCCTGGTGACCCGGAGGTGGCCTGTACG
  GCCCACAAAGTCACGCCCGTGGACCCCAACGCGCTCTCCTTCTCCCTGCTCGTCGGGGGC
  CAGGAACTGGAGGGGGCGCAAGCCCTGGGCCCGGAGGTGCAGGAGGAGGAGGAGGAGCCC
  CAGGGGGACGAGGACGTGCTGTTCAGGGTGACAGAGCGCTGGCGGCTGCCGCCCCTGGGG
  ACCCCTGTCCCGCCCGCCCTCTACTGCCAGGCCACGATGAGGCTGCCTGGCTTGGAGCTC
  AGCCACCGCCAGGCCATCCCCGCGTCCAAACCTGCGGGTGACCAGCTGCCCGCGGCTCTG
  TGGACCAGCAGTGCGGTGCTGGGACTGCTGCTCCTGGCCTTGCCCACCTATCACCTCTGG
  AAACGCTGCCGGCACCTGGCTGAGGACGACACCCACCCACCGGCTTCTCTGAGGCTTCTG
  CCCCAGGTGTCGGCCTGGGCTGGGTTAAGGGGGACCGGCCAGGTCGGGATCAGCCCCTCC
  TGAGTGGCCAGCCTTTCCCCCTGTGAAAGCAAAATAGCTTGGACCCCTTCAAGTTGAGAA
  CTGGTCAGGGCAAACCTGCCTCCCATTCTACTCAAAGTCATCCCTCTGCTCACAGAGATG
  GATGCATGTTCTGATTGCCTCTTTGGAGAAGCTCATCAGAAACTCAAAAGAAGGCCACTG
  TTTGTCTCACCTACCCATGACCTGAAGCCCCTCCCTGAGTGGTCCCCACCTTTCTGGACG
  GAACCACGTACTTTTTACATACATTGATTCATGTCTCACGTCTCCCTAAAAATGCGTAAG
  ACCAAGCTGTGCCCTGACCACCCTGGGCCCCTGTCGTCAGGACCTCCTGAGGCTTTGGCA
  AATAAACCTCCTAAAATGATAAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_130762 unedited
  NGGGGAGTTCAAATTTGTATACGACTCATATAGGCGGCCGCGATTCATGGATTTCGGACT
  GGCCCTCCTGCTGGCGGGGCTTCTGGGGCTCCTCCTCGGCCAGTCCCTCCAGGTGAAGCC
  CCTGCAGGTGGAGCCCCCGGAGCCGGTGGTGGCCGTGGCCTTGGGCGCCTCGCGCCAGCT
  CACCTGCCGCCTGGCCTGCGCGGACCGCGGGGCCTCGGTGCAGTGGCGGGGCCTGGACAC
  CAGCCTGGGCGCGGTGCAGTCGGACACGGGCCGCAGCGTCCTCACCGTGCGCAACGCCTC
  GCTGTCGGCGGCCGGGACCCGCGTGTGCGTGGGCTCCTGCGGGGGCCGCACCTTCCAGCA
  CACCGTGCAGCTCCTTGTGTACGCCTTCCCGGACCAGCTGACCGTCTCCCCGGCAGCCCT
  GGTGCCTGGTGACCCGGAGGTGGCCTGTACGGCCCACAAAGTCACGCCCGTGGACCCCAA
  CGCGCTCTCCTTCTCCCTGCTCGTCGGGGGCCAGGAACTGGAGGGGGCGCAAGCCCTGGG
  CCCGGAGGTGCANGAGGAGGAGGAGGAGCCCCAGGGGGACGAGGACGTGCTGTTCAGGGT
  GACAGAGCGCTGGCGGCTGCCGCCCCTGGGGACCCCTGTCCCGCCCGCCCTCTACTGCCA
  GGCCACGATGAGGCTGCCTGGCTTGGAGCTCAGCCACCGCCAGGCCATCCCCGCGTCCAA
  ACCTGCGGGTGACCAGCTGCCCGCGGCTCTGTGGACCAGCAGTGCGGTGCTGGGACTGCT
  GCTCCTGGCCTTGCCCACCTATCACCTCTGGAAACGCTGCCGGCACCTGGCTNGAGACGA
  CACCCACCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_130762 unedited
  CATTGGNGAATGGCACTTNCCAGGNCCAGGNGAAAGCACTGGGNGNAGGGGTCACAGGGN
  ATGCCACCCGGGNNATCTGTTCAGGNAAACAGCTATGACCGCGGCCGCAATCTAGAGTCG
  AGTTTTTTTTTTTTTTTTTTTATCATTTTAGGAGGTTTATTTGCCAAAGCCTCAGGAGGT
  CCTGACGACAGGGGCCCAGGGTGGTCAGGGCACAGCTTGGTCTTACGCATTTTTAGGGAG
  ACGTGAGACATGAATCAATGTATGTAAAAAGTACGTGGTTCCGTCCAGAAAGGTGGGGAC
  CACTCAGGGAGGGGCTTCAGGTCATGGGTAGGTGAGACAAACAGTGGCCTTCTTTTGAGT
  TTCTGATGAGCTTCTCCAAAGAGGCAATCAGAACATGCATCCATCTCTGTGAGCAGAGGG
  ATGACTTTGAGTAGAATGGGAGGCAGGTTTGCCCTGACCAGTTCTCAACTTGAAGGGGTC
  CAAGCTATTTTGCTTTCACAGGGGGAAAGGCTGGCCACTCAGGAGGGGCTGATCCCGACC
  TGGCCGGTCCCCCTTAACCCAGCCCAGGCCGACACCTGNGGCAGAAGCCTCAGAAAGCCG
  GTGGGTTGGGTGTCGTCCTCAGCCAGGTGCCGGCAGCGTTTCCAGAGGTGATAGGTGGGC
  AAGGCCAGGAGCAGCAGTCCCAGCACCGCACTGCTGGTCCACAGAGCCGCGGGCAGCTGG
  TCACCCCGCAGTTTGGACGCGGGGATGGCTTGGCGGGGGGTGAGCTCCAGCCCAGCAGCC
  TCATCGTGGCCTTGCAATAAAGGGCGGGCGGGAAAGGGGGTCCCCAGGGGGCGGAGCCGC
  C
  
• Restriction Sites: Please inquire
• ACCN: NM_130762
• ORF Size: 888 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_130762.1, NP_570118.1
• RefSeq Size: 1275
• RefSeq ORF: 888
• Locus ID: 8174
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform b) that lacks an internal segment, compared to isoform a.