PTPRS (NM_130854) Human Untagged Clone

CAT#: SC305922

PTPRS (untagged)-Human protein tyrosine phosphatase, receptor type, S (PTPRS), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRS
• Synonyms: PTPSIGMA; R-PTP-S; R-PTP-sigma
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_130854 edited
  CGCACGCCGCGAGCCGCTGGCGCTCGGGCTCCGCTCGGATCCCATGCAACAGCCACGATG
  TGAAGCGGGGCAGAGCCGGGGGAGCCCAGCCCAGCCAGCCTCCAGACGTTGCCCCATCTG
  ACGCTCGGCTCGAGGCCTCTCTGTGAGGGACCGGGGGGCCATCCCCCTCCAGGGCGGAGA
  TCGGAGGTCGCTGCCAAGCATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTGG
  TCCCATGGGCCTCCTTGTGGTCCTGCTCGTTGGAGGCTGTGCAGCAGAAGAGCCCCCCAG
  GTTTATCAAAGAACCCAAGGACCAGATCGGCGTGTCGGGGGGTGTGGCCTCTTTCGTGTG
  TCAGGCCACGGGTGACCCCAAGCCACGAGTGACCTGGAACAAGAAGGGCAAGAAGGTCAA
  CTCTCAGCGCTTTGAGACGATTGAGTTTGATGAGAGTGCAGGGGCAGTGCTGAGGATCCA
  GCCGCTGAGGACACCGCGGGATGAAAACGTGTACGAGTGTGTGGCCCAGAACTCGGTTGG
  GGAGATCACAGTCCATGCCAAGCTTACTGTCCTCCGAGAGGACCAGCTGCCCTCTGGCTT
  CCCCAACATCGACATGGGCCCACAGTTGAAGGTGGTGGAGCGGACACGGACAGCCACCAT
  GCTCTGTGCAGCCAGCGGCAACCCTGACCCTGAGATCACCTGGTTCAAGGACTTCCTGCC
  TGTGGATCCTAGTGCCAGCAATGGACGCATCAAACAGCTGCGATCAGGAGCCCTGCAGAT
  TGAAAGCAGTGAGGAAACCGACCAGGGCAAATATGAGTGTGTGGCCACCAACAGCGCCGG
  CGTGCGCTACTCCTCACCTGCCAACCTCTACGTGCGAGTCCGCCGCGTGGCCCCGCGCTT
  CTCCATCCTGCCCATGAGCCACGAGATCATGCCAGGGGGCAACGTGAACATCACCTGCGT
  GGCCGTGGGCTCGCCCATGCCATACGTGAAGTGGATGCAGGGGGCCGAGGACCTGACCCC
  CGAGGATGACATGCCCGTGGGTCGGAACGTGCTGGAACTCACAGATGTCAAGGACTCGGC
  CAACTACACCTGCGTGGCCATGTCCAGCCTGGGCGTCATTGAGGCGGTTGCTCAGATCAC
  GGTGAAATCTCTCCCCAAAGCTCCCGGGACTCCCATGGTGACTGAGAACACAGCCACCAG
  CATCACCATCACGTGGGACTCGGGCAACCCAGATCCTGTGTCCTATTACGTCATCGAATA
  TAAATCCAAGAGCCAAGACGGGCCGTATCAGATTAAAGAGGACATCACCACCACACGTTA
  CAGCATCGGCGGCCTGAGCCCCAACTCGGAGTACGAGATCTGGGTGTCGGCCGTCAACTC
  CATCGGCCAGGGGCCCCCCAGCGAGTCCGTGGTCACCCGCACAGGCGAGCAGGCCCCGGC
  CAGCGCGCCGCGGAACGTGCAAGCCCGGATGCTCAGCGCGACCACCATGATTGTGCAGTG
  GGAGGAGCCGGTGGAGCCCAACGGCCTGATCCGCGGCTACCGCGTCTACTACACCATGGA
  ACCGGAGCACCCCGTGGGCAACTGGCAGAAGCACAACGTGGACGACAGCCTGCTGACCAC
  CGTGGGCAGCCTGCTGGAGGACGAGACCTACACCGTGCGGGTGCTCGCCTTCACCTCCGT
  CGGCGACGGGCCCCTCTCGGACCCCATCCAGGTCAAGACGCAGCAGGGAGTGCCGGGCCA
  GCCCATGAACCTGCGGGCCGAGGCCAGGTCGGAGACCAGCATCACGCTGTCCTGGAGCCC
  CCCGCGGCAGGAGAGTATCATCAAGTACGAGCTCCTCTTCCGGGAAGGCGACCATGGCCG
  GGAGGTGGGAAGGACCTTCGACCCGACGACTTCCTACGTGGTGGAGGACCTGAAGCCCAA
  CACGGAGTACGCCTTCCGCCTGGCGGCCCGCTCGCCGCAGGGCCTGGGCGCCTTCACCCC
  CGTGGTGCGGCAGCGCACGCTGCAGTCCAAACCGTCAGCCCCCCCTCAAGACGTTAAATG
  TGTCAGCGTGCGCTCCACGGCCATTTTGGTAAGTTGGCGCCCGCCGCCGCCGGAAACGCA
  CAACGGGGCCCTGGTGGGCTACAGCGTCCGCTACCGACCGCTGGGCTCAGAGGACCCGGA
  ACCCAAGGAGGTGAACGGCATCCCCCCGACCACCACTCAGATCCTGCTGGAGGCCTTGGA
  GAAGTGGACCCAGTACCGCATCACGACTGTCGCTCACACAGAGGTGGGACCAGGGCCCGA
  GAGCTCGCCCGTGGTCGTCCGCACCGACGAGGATGTGCCCAGCGCGCCGCCGCGGAAGGT
  GGAGGCGGAGGCGCTCAACGCCACGGCCATCCGCGTGCTGTGGCGCTCGCCCGCGCCCGG
  CCGGCAGCACGGCCAGATCCGCGGCTACCAGGTCCACTACGTGCGCATGGAGGGCGCCGA
  GGCCCGCGGGCCGCCGCGCATCAAGGACGTCATGCTGGCCGATGCCCAGGAGATGGTCAT
  CACAAACTTGCAGCCTGAGACCGCGTACTCCATCACGGTAGCCGCCTACACCATGAAGGG
  CGATGGCGCTCGCAGCAAACCCAAGGTGGTTGTGACCAAGGGAGCAGTGCTGGGCCGCCC
  AACCCTGTCGGTGCAGCAGACCCCCGAGGGCAGCCTGCTGGCACGCTGGGAGCCCCCGGC
  TGGCACCGCGGAGGACCAGGTGCTGGGCTACCGCCTGCAGTTTGGCCGTGAGGACTCGAC
  GCCCCTGGCCACCCTGGAGTTCCCGCCCTCCGAGGACCGCTACACGGCATCAGGCGTGCA
  CAAGGGGGCCACGTATGTGTTCCGGCTTGCGGCCCGGAGCCGCGGCGGCCTGGGCGAGGA
  GGCAGCCGAGGTCCTGAGCATCCCGGAGGACACGCCCCGTGGCCACCCGCAGATTCTGGA
  GGCGGCCGGCAACGCCTCGGCCGGGACCGTCCTTCTCCGCTGGCTGCCACCCGTGCCCGC
  CGAGCGCAACGGGGCCATCGTCAAATACACGGTGGCCGTGCGGGAGGCCGGTGCCCTGGG
  CCCTGCCCGAGAGACTGAGCTGCCGGCAGCGGCTGAGCCGGGCGCGGAGAACGCGCTCAC
  GCTGCAGGGCCTGAAGCCCGACACGGCCTATGACCTCCAAGTGCGAGCCCACACGCGCCG
  GGGCCCTGGCCCCTTCAGCCCCCCCGTCCGCTACCGGACGTTCCTGCGGGACCAAGTCTC
  GCCCAAGAACTTCAAGGTGAAAATGATCATGAAGACATCAGTTCTGCTCAGCTGGGAGTT
  CCCTGACAACTACAACTCACCCACACCCTACAAGATCCAGTACAATGGGCTCACACTGGA
  TGTGGATGGCCGTACCACCAAGAAGCTCATCACGCACCTCAAGCCCCACACCTTCTACAA
  CTTTGTGCTGACCAATCGCGGCAGCAGCCTGGGCGGCCTCCAGCAGACGGTCACCGCCTG
  GACTGCCTTCAACCTGCTCAACGGCAAGCCCAGCGTCGCCCCCAAGCCTGATGCTGACGG
  CTTCATCATGGTGTATCTTCCTGACGGCCAGAGCCCCGTGCCTGTCCAGAGCTATTTCAT
  TGTGATGGTGCCACTGCGCAAGTCTCGTGGAGGCCAATTCCTGACCCCGCTGGGTAGCCC
  AGAGGACATGGATCTGGAAGAGCTCATCCAGGACATCTCACGGCTACAGAGGCGCAGCCT
  GCGGCACTCGCGTCAGCTGGAGGTGCCCCGGCCCTATATTGCAGCTCGCTTCTCTGTGCT
  GCCACCCACGTTCCATCCCGGCGACCAGAAGCAGTATGGCGGCTTCGATAACCGGGGCCT
  GGAGCCCGGCCACCGCTATGTCCTCTTCGTGCTTGCCGTGCTTCAGAAGAGCGAGCCTAC
  CTTTGCAGCCAGTCCCTTCTCAGACCCCTTCCAGCTGGATAACCCGGACCCCCAGCCCAT
  CGTGGATGGCGAGGAGGGGCTTATCTGGGTGATCGGGCCTGTGCTGGCCGTGGTCTTCAT
  AATCTGCATTGTCATTGCTATCCTGCTCTACAAGAACAAACCCGACAGTAAACGCAAGGA
  CTCAGAACCCCGCACCAAATGCCTCCTGAACAATGCCGACCTCGCCCCTCACCACCCCAA
  GGACCCTGTGGAAATGAGACGCATTAACTTCCAGACTCCAGGCATGCTTAGCCACCCGCC
  AATTCCCATCGCAGACATGGCGGAGCACACGGAGCGGCTCAAGGCCAACGACAGCCTCAA
  GCTCTCCCAGGAGTATGAGTCCATCGACCCTGGACAGCAGTTCACATGGGAACATTCCAA
  CCTGGAAGTGAACAAGCCGAAGAACCGCTATGCCAACGTCATCGCCTATGACCACTCCCG
  TGTCATCCTCCAGCCCATTGAAGGCATCATGGGCAGTGATTACATCAATGCCAACTACGT
  GGACGGCTACCGGCGTCAGAACGCGTACATTGCCACGCAGGGGCCGCTGCCTGAGACCTT
  TGGGGACTTCTGGCGTATGGTGTGGGAGCAGCGGTCGGCGACCATCGTCATGATGACGCG
  GCTGGAGGAGAAGTCACGGATCAAGTGTGATCAGTATTGGCCCAACAGAGGCACGGAGAC
  CTACGGCTTCATCCAGGTCACGTTGCTAGATACCATCGAGCTGGCCACATTCTGCGTCAG
  GACATTCTCTCTGCACAAGAATGGCTCCAGTGAGAAACGCGAGGTCCGCCAGTTCCAGTT
  TACGGCGTGGCCGGACCATGGCGTGCCCGAATACCCAACGCCCTTCCTGGCTTTCCTGCG
  GAGAGTCAAGACCTGCAACCCGCCAGATGCCGGCCCCATCGTGGTTCACTGCAGTGCCGG
  TGTGGGCCGCACAGGCTGCTTTATCGTCATCGACGCCATGCTTGAGCGGATCAAGCCAGA
  GAAGACAGTCGATGTCTATGGCCACGTGACGCTCATGAGGTCCCAGCGCAACTACATGGT
  GCAGACGGAGGACCAGTACAGCTTCATCCACGAGGCCCTGCTGGAGGCCGTGGGCTGTGG
  CAACACAGAAGTGCCCGCACGCAGCCTCTATGCCTACATCCAGAAGCTGGCCCAGGTGGA
  GCCTGGCGAACACGTCACTGGCATGGAACTCGAGTTCAAGCGGCTGGCTAACTCCAAGGC
  CCACACGTCACGCTTCATCAGTGCCAATCTGCCTTGTAACAAGTTCAAGAACCGCCTGGT
  GAACATCATGCCCTATGAGAGCACACGGGTCTGTCTGCAACCCATCCGGGGTGTGGAGGG
  CTCTGACTACATCAACGCCAGCTTCATTGATGGCTACAGGCAGCAGAAGGCCTACATCGC
  GACACAGGGGCCGCTGGCGGAGACCACGGAAGACTTCTGGCGCATGCTGTGGGAGAACAA
  TTCGACGATCGTGGTGATGCTGACCAAGCTGCGGGAGATGGGCCGGGAGAAGTGTCACCA
  GTACTGGCCGGCCGAGCGCTCTGCCCGCTACCAGTACTTTGTGGTAGATCCGATGGCAGA
  ATACAACATGCCTCAGTATATCCTGCGAGAGTTCAAGGTCACAGATGCCCGGGATGGCCA
  GTCCCGGACTGTCCGGCAGTTCCAGTTCACAGACTGGCCGGAACAGGGTGTGCCAAAGTC
  GGGGGAGGGCTTCATCGACTTCATTGGCCAAGTGCATAAGACTAAGGAGCAGTTTGGCCA
  GGACGGCCCCATCTCTGTCCACTGCAGTGCCGGCGTGGGCAGGACGGGCGTCTTCATCAC
  GCTTAGCATCGTGCTGGAGCGGATGCGGTATGAAGGCGTGGTGGACATCTTTCAGACGGT
  GAAGATGCTACGAACCCAGCGGCCGGCCATGGTGCAGACAGAGGATGAGTACCAGTTCTG
  TTACCAGGCGGCACTGGAGTACCTCGGAAGCTTTGACCACTATGCAACCTAAAGCCATGG
  TCCCCCCCAGGCCCGACACCACTGGCCCCGGATGCCTCTGCCCCTCCCGGGCGGACCTCC
  TGAGGCCTGGACCCCCAGTGGGCAGGGCAGGAGGTGGCAGCGGCAGCAGCTGTGTTTCTG
  CACCATTTCCGAGGACGACGCAGCCCCTCGAGCCCCCCCACCGGCCCCGGCCGCCCCAGC
  GACCTCCCTGGCACCGGCCGCCGCCTTCAAATACTTGGCACATTCCTCCTTTCCTTCCAA
  TTCCAAAACCAGATTCCGGGGTGGGGGGTGGGGGGATGGTGAGCAAATAGGAGTGCTCCC
  CAGAACCAGAGGAGGGTGGGGCACAGACCATAGACGGACCCCTCGTCCTCCCCCAGCGGT
  GGTAGGGGGACCCGGGGGGCTCCTCCCCGCTCTGCAGCCTGGGGACACTGGGCTGGGACC
  AGAATCCAGCTTTCTTTTAAAACTCTCAGTGTAACTGTATCCCGTGACATTTCATTTTTT
  TTAAATAGTGTATTTTTTTTTCCATTTTTTTTTTTAAGAGAAACAAACAAAAGACTCGCC
  AGTCAATGACTTTCAAAGAGAACTAACTTTGGCTTATTCATATTCTGTTCAAAGACAGTC
  TATTTTTTCACTGTAGAAAGCGTCCTTGTGTGATAGTTACGTTCGCAAACGCGCACGCCA
  GGCCCATGGCTGTACCTTGGCTTTTTTTTTTTTTTTTTTTTTTTTAATTTTTCCTACCAT
  CAGAAAGTGTGCTTTGCTCACAGAAGAATGGGATGTCCTTTTTTCTTTCTTGGCTTTTTT
  TTTCCCCCTTTTTGTTTCATTTTTATAAATTAAATTTTCAGACATATCAAATACAGTTCT
  GAGGGTAAGGTCATGGGGGAGCTCGGACCCAGTGGCGTTGGGTGCGGTTGAGGGGGACGC
  TGCTGTAAGAGGAGAGAGATGACAGTGGTCCTCCTCTGAGAGCCTGAGCTGTCTCCCCGT
  CTCCCGCCCCCAAGGAGACAGAGAGGATCCTACTTCTTCGGGGACAGTGGCTGTATGGCT
  GTGCTGCCCCACATCAGGGACCCTTTCCCCCTGGGACTGTGGGGCAGTTTGGGAGCAAAA
  CCAGAAGGACAGGCCCCCCTCTACCCGCCTACCCTGAGCAAGCGAGTTGTTCCTCTTTGT
  ACAAGGGCAGGTCTGCGGTTACTTTCAACACTGTTTATTCCAGCGGAAGCAGCCGGGTGG
  TTTTCCCACCCCCGTGTATGTAGATATATCGACTTTGTATTAAAGGAAGATCGTCTGACC
  CCGGCCCATTGTGGAGT
  
• Restriction Sites: Please inquire
• ACCN: NM_130854
• ORF Size: 5733 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid.

Reference Data

• RefSeq: NM_130854.1, NP_570924.1
• RefSeq Size: 6386
• RefSeq ORF: 5733
• Locus ID: 5802
• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks four internal fragments within the coding region when compared to variant 1. The translation remains in-frame, and thus results in a protein that lacks four internal segments, as compared to isoform 1. Sequence Note: The transcript 3'UTR sequence was derived from a genomic record (AC118535.1) based on a series of overlapping EST alignments.