PTPRS (NM_130855) Human Untagged Clone

CAT#: SC305923

PTPRS (untagged)-Human protein tyrosine phosphatase, receptor type, S (PTPRS), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRS
• Synonyms: PTPSIGMA; R-PTP-S; R-PTP-sigma
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_130855 edited
  GCGCACGCCGCGAGCCGCTGGCGCTCGGGCTCCGCTCGGATCCCATGCAACAGCCACGAT
  GTGAAGCGGGGCAGAGCCGGGGGAGCCCAGCCCAGCCAGCCTCCAGACGTTGCCCCATCT
  GACGCTCGGCTCGAGGCCTCTCTGTGAGGGACCGGGGGGCCATCCCCCTCCAGGGCGGAG
  ATCGGAGGTCGCTGCCAAGCATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTG
  GTCCCATGGGCCTCCTTGTGGTCCTGCTCGTTGGAGGCTGTGCAGCAGAAGAGCCCCCCA
  GGTTTATCAAAGAACCCAAGGACCAGATCGGCGTGTCGGGGGGTGTGGCCTCTTTCGTGT
  GTCAGGCCACGGGTGACCCCAAGCCACGAGTGACCTGGAACAAGAAGGGCAAGAAGGTCA
  ACTCTCAGCGCTTTGAGACGATTGAGTTTGATGAGAGTGCAGGGGCAGTGCTGAGGATCC
  AGCCGCTGAGGACACCGCGGGATGAAAACGTGTACGAGTGTGTGGCCCAGAACTCGGTTG
  GGGAGATCACAGTCCATGCCAAGCTTACTGTCCTCCGAGAGGACCAGCTGCCCTCTGGCT
  TCCCCAACATCGACATGGGCCCACAGTTGAAGGTGGTGGAGCGGACACGGACAGCCACCA
  TGCTCTGTGCAGCCAGCGGCAACCCTGACCCTGAGATCACCTGGTTCAAGGACTTCCTGC
  CTGTGGATCCTAGTGCCAGCAATGGACGCATCAAACAGCTGCGATCAGGAGCCCTGCAGA
  TTGAAAGCAGTGAGGAAACCGACCAGGGCAAATATGAGTGTGTGGCCACCAACAGCGCCG
  GCGTGCGCTACTCCTCACCTGCCAACCTCTACGTGCGAGAGCTTCGAGAAGTCCGCCGCG
  TGGCCCCGCGCTTCTCCATCCTGCCCATGAGCCACGAGATCATGCCAGGGGGCAACGTGA
  ACATCACCTGCGTGGCCGTGGGCTCGCCCATGCCATACGTGAAGTGGATGCAGGGGGCCG
  AGGACCTGACCCCCGAGGATGACATGCCCGTGGGTCGGAACGTGCTGGAACTCACAGATG
  TCAAGGACTCGGCCAACTACACCTGCGTGGCCATGTCCAGCCTGGGCGTCATTGAGGCGG
  TTGCTCAGATCACGGTGAAATCTCTCCCCAAAGCTCCCGGGACTCCCATGGTGACTGAGA
  ACACAGCCACCAGCATCACCATCACGTGGGACTCGGGCAACCCAGATCCTGTGTCCTATT
  ACGTCATCGAATATAAATCCAAGAGCCAAGACGGGCCGTATCAGATTAAAGAGGACATCA
  CCACCACACGTTACAGCATCGGCGGCCTGAGCCCCAACTCGGAGTACGAGATCTGGGTGT
  CGGCCGTCAACTCCATCGGCCAGGGGCCCCCCAGCGAGTCCGTGGTCACCCGCACAGGCG
  AGCAGGCCCCGGCCAGCGCGCCGCGGAACGTGCAAGCCCGGATGCTCAGCGCGACCACCA
  TGATTGTGCAGTGGGAGGAGCCGGTGGAGCCCAACGGCCTGATCCGCGGCTACCGCGTCT
  ACTACACCATGGAACCGGAGCACCCCGTGGGCAACTGGCAGAAGCACAACGTGGACGACA
  GCCTGCTGACCACCGTGGGCAGCCTGCTGGAGGACGAGACCTACACCGTGCGGGTGCTCG
  CCTTCACCTCCGTCGGCGACGGGCCCCTCTCGGACCCCATCCAGGTCAAGACGCAGCAGG
  GAGTGCCGGGCCAGCCCATGAACCTGCGGGCCGAGGCCAGGTCGGAGACCAGCATCACGC
  TGTCCTGGAGCCCCCCGCGGCAGGAGAGTATCATCAAGTACGAGCTCCTCTTCCGGGAAG
  GCGACCATGGCCGGGAGGTGGGAAGGACCTTCGACCCGACGACTTCCTACGTGGTGGAGG
  ACCTGAAGCCCAACACGGAGTACGCCTTCCGCCTGGCGGCCCGCTCGCCGCAGGGCCTGG
  GCGCCTTCACCCCCGTGGTGCGGCAGCGCACGCTGCAGTCCATCTCGCCCAAGAACTTCA
  AGGTGAAAATGATCATGAAGACATCAGTTCTGCTCAGCTGGGAGTTCCCTGACAACTACA
  ACTCACCCACACCCTACAAGATCCAGTACAATGGGCTCACACTGGATGTGGATGGCCGTA
  CCACCAAGAAGCTCATCACGCACCTCAAGCCCCACACCTTCTACAACTTTGTGCTGACCA
  ATCGCGGCAGCAGCCTGGGCGGCCTCCAGCAGACGGTCACCGCCTGGACTGCCTTCAACC
  TGCTCAACGGCAAGCCCAGCGTCGCCCCCAAGCCTGATGCTGACGGCTTCATCATGGTGT
  ATCTTCCTGACGGCCAGAGCCCCGTGCCTGTCCAGAGCTATTTCATTGTGATGGTGCCAC
  TGCGCAAGTCTCGTGGAGGCCAATTCCTGACCCCGCTGGGTAGCCCAGAGGACATGGATC
  TGGAAGAGCTCATCCAGGACATCTCACGGCTACAGAGGCGCAGCCTGCGGCACTCGCGTC
  AGCTGGAGGTGCCCCGGCCCTATATTGCAGCTCGCTTCTCTGTGCTGCCACCCACGTTCC
  ATCCCGGCGACCAGAAGCAGTATGGCGGCTTCGATAACCGGGGCCTGGAGCCCGGCCACC
  GCTATGTCCTCTTCGTGCTTGCCGTGCTTCAGAAGAGCGAGCCTACCTTTGCAGCCAGTC
  CCTTCTCAGACCCCTTCCAGCTGGATAACCCGGACCCCCAGCCCATCGTGGATGGCGAGG
  AGGGGCTTATCTGGGTGATCGGGCCTGTGCTGGCCGTGGTCTTCATAATCTGCATTGTCA
  TTGCTATCCTGCTCTACAAGAACAAACCCGACAGTAAACGCAAGGACTCAGAACCCCGCA
  CCAAATGCCTCCTGAACAATGCCGACCTCGCCCCTCACCACCCCAAGGACCCTGTGGAAA
  TGAGACGCATTAACTTCCAGACTCCAGGCATGCTTAGCCACCCGCCAATTCCCATCGCAG
  ACATGGCGGAGCACACGGAGCGGCTCAAGGCCAACGACAGCCTCAAGCTCTCCCAGGAGT
  ATGAGTCCATCGACCCTGGACAGCAGTTCACATGGGAACATTCCAACCTGGAAGTGAACA
  AGCCGAAGAACCGCTATGCCAACGTCATCGCCTATGACCACTCCCGTGTCATCCTCCAGC
  CCATTGAAGGCATCATGGGCAGTGATTACATCAATGCCAACTACGTGGACGGCTACCGGC
  GTCAGAACGCGTACATTGCCACGCAGGGGCCGCTGCCTGAGACCTTTGGGGACTTCTGGC
  GTATGGTGTGGGAGCAGCGGTCGGCGACCATCGTCATGATGACGCGGCTGGAGGAGAAGT
  CACGGATCAAGTGTGATCAGTATTGGCCCAACAGAGGCACGGAGACCTACGGCTTCATCC
  AGGTCACGTTGCTAGATACCATCGAGCTGGCCACATTCTGCGTCAGGACATTCTCTCTGC
  ACAAGAATGGCTCCAGTGAGAAACGCGAGGTCCGCCAGTTCCAGTTTACGGCGTGGCCGG
  ACCATGGCGTGCCCGAATACCCAACGCCCTTCCTGGCTTTCCTGCGGAGAGTCAAGACCT
  GCAACCCGCCAGATGCCGGCCCCATCGTGGTTCACTGCAGTGCCGGTGTGGGCCGCACAG
  GCTGCTTTATCGTCATCGACGCCATGCTTGAGCGGATCAAGCCAGAGAAGACAGTCGATG
  TCTATGGCCACGTGACGCTCATGAGGTCCCAGCGCAACTACATGGTGCAGACGGAGGACC
  AGTACAGCTTCATCCACGAGGCCCTGCTGGAGGCCGTGGGCTGTGGCAACACAGAAGTGC
  CCGCACGCAGCCTCTATGCCTACATCCAGAAGCTGGCCCAGGTGGAGCCTGGCGAACACG
  TCACTGGCATGGAACTCGAGTTCAAGCGGCTGGCTAACTCCAAGGCCCACACGTCACGCT
  TCATCAGTGCCAATCTGCCTTGTAACAAGTTCAAGAACCGCCTGGTGAACATCATGCCCT
  ATGAGAGCACACGGGTCTGTCTGCAACCCATCCGGGGTGTGGAGGGCTCTGACTACATCA
  ACGCCAGCTTCATTGATGGCTACAGGCAGCAGAAGGCCTACATCGCGACACAGGGGCCGC
  TGGCGGAGACCACGGAAGACTTCTGGCGCATGCTGTGGGAGAACAATTCGACGATCGTGG
  TGATGCTGACCAAGCTGCGGGAGATGGGCCGGGAGAAGTGTCACCAGTACTGGCCGGCCG
  AGCGCTCTGCCCGCTACCAGTACTTTGTGGTAGATCCGATGGCAGAATACAACATGCCTC
  AGTATATCCTGCGAGAGTTCAAGGTCACAGATGCCCGGGATGGCCAGTCCCGGACTGTCC
  GGCAGTTCCAGTTCACAGACTGGCCGGAACAGGGTGTGCCAAAGTCGGGGGAGGGCTTCA
  TCGACTTCATTGGCCAAGTGCATAAGACTAAGGAGCAGTTTGGCCAGGACGGCCCCATCT
  CTGTCCACTGCAGTGCCGGCGTGGGCAGGACGGGCGTCTTCATCACGCTTAGCATCGTGC
  TGGAGCGGATGCGGTATGAAGGCGTGGTGGACATCTTTCAGACGGTGAAGATGCTACGAA
  CCCAGCGGCCGGCCATGGTGCAGACAGAGGATGAGTACCAGTTCTGTTACCAGGCGGCAC
  TGGAGTACCTCGGAAGCTTTGACCACTATGCAACCTAAAGCCATGGTCCCCCCCAGGCCC
  GACACCACTGGCCCCGGATGCCTCTGCCCCTCCCGGGCGGACCTCCTGAGGCCTGGACCC
  CCAGTGGGCAGGGCAGGAGGTGGCAGCGGCAGCAGCTGTGTTTCTGCACCATTTCCGAGG
  ACGACGCAGCCCCTCGAGCCCCCCCACCGGCCCCGGCCGCCCCAGCGACCTCCCTGGCAC
  GGCCGCCGCCTTCAAATACTTGGCACATTCCTCCTTTCCTTCCAATTCCAAAACCAGATT
  CCGGGGTGGGGGGTGGGGGGATGGTGAGCAAATAGGAGTGCTCCCCAGAACCAGAGGAGG
  GTGGGGCACAGACCATAGACGGACCCCTCGTCCTCCCCCAGCGGTGGTAGGGGGACCCGG
  GGGGCTCCTCCCCGCTCTGCAGCCTGGGGACACTGGGCTGGGACCAGAATCCAGCTTTCT
  TTTAAAACTCTCAGTGTAACTGTATCCCGTGACATTTCATTTTTTTTAAATAGTGTATTT
  TTTTTTCCATTTTTTTTTTTAAGAGAAACAAACAAAAGACTCGCCAGTCAATGACTTTCA
  AAGAGAACTAACTTTGGCTTATTCATATTCTGTTCAAAGACAGTCTATTTTTTCACTGTA
  GAAAGCGTCCTTGTGTGATAGTTACGTTCGCAAACGCGCACGCCAGGCCCATGGCTGTAC
  CTTGGCTTTTTTTTTTTTTTTTTTTTTTTTAATTTTTCCTACCATCAGAAAGTGTGCTTT
  GCTCACAGAAGAATGGGATGTCCTTTTTTCTTTCTTGGCTTTTTTTTTCCCCCTTTTTGT
  TTCATTTTTATAAATTAAATTTTCAGACATATCAAATACAGTTCTGAGGGTAAGGTCATG
  GGGGAGCTCGGACCCAGTGGCGTTGGGTGCGGTTGAGGGGGACGCTGCTGTAAGAGGAGA
  GAGATGACAGTGGTCCTCCTCTGAGAGCCTGAGCTGTCTCCCCGTCTCCCGCCCCCAAGG
  AGACAGAGAGGATCCTACTTCTTCGGGGACAGTGGCTGTATGGCTGTGCTGCCCCACATC
  AGGGACCCTTTCCCCCTGGGACTGTGGGGCAGTTTGGGAGCAAAACCAGAAGGACAGGCC
  CCCCTCTACCCGCCTACCCTGAGCAAGCGAGTTGTTCCTCTTTGTACAAGGGCAGGTCTG
  CGGTTACTTTCAACACTGTTTATTCCAGCGGAAGCAGCCGGGTGGTTTTCCCACCCCCGT
  GTATGTAGATATATCGACTTTGTATTAAAGGAAGATCGTCTGACCCCGGCCCATTGTGGA
  GT
  
• Restriction Sites: Please inquire
• ACCN: NM_130855
• ORF Size: 4518 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid.

Reference Data

• RefSeq: NM_130855.1, NP_570925.1
• RefSeq Size: 5171
• RefSeq ORF: 4518
• Locus ID: 5802
• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (4) lacks three internal fragments within the coding region when compared to variant 1. The translation remains in-frame, and thus results in a protein that lacks three internal segments, as compared to isoform 1. Sequence Note: The transcript 3'UTR sequence was derived from a genomic record (AC118535.1) based on a series of overlapping EST alignments.