SHANK2 (NM_133266) Human Untagged Clone
CAT#: SC305939
SHANK2 (untagged)-Human SH3 and multiple ankyrin repeat domains 2 (SHANK2), transcript variant 2
"NM_133266" in other vectors (5)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | SHANK2 |
Synonyms | AUTS17; CORTBP1; CTTNBP1; ProSAP1; SHANK; SPANK-3 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_133266, the custom clone sequence may differ by one or more nucleotides
ATGATGATGAACGTCCCCGGCGGAGGAGCGGCCGCGGTGATGATGACGGGCTACAATAAT GGTCGCTGTCCCCGGAATTCTCTCTACAGTGACTGCATTATTGAGGAGAAGACGGTGGTC CTGCAGAAAAAAGACAATGAGGGCTTTGGATTCGTGCTTCGAGGGGCCAAAGCTGACACA CCCATTGAAGAATTCACACCAACACCGGCTTTCCCAGCCCTACAGTACCTGGAGTCCGTG GATGAAGGTGGGGTGGCGTGGCAAGCCGGACTAAGGACCGGGGACTTCTTGATTGAGGTT AACAATGAGAATGTTGTCAAAGTCGGCCACAGGCAGGTGGTGAACATGATCCGGCAGGGA GGGAATCACCTGGTCCTTAAGGTGGTCACGGTGACCAGGAATCTGGACCCCGACGACACC GCCAGGAAGAAAGCTCCCCCGCCTCCAAAGCGGGCACCGACCACAGCCCTCACCCTGCGC TCCAAGTCCATGACCTCGGAGCTGGAGGAGCTCGTGGATAAAGCCTCGGTCCGGAAGAAG AAGGATAAACCCGAGGAGATAGTCCCGGCCTCCAAGCCCTCCCGCGCTGCTGAGAACATG GCTGTGGAACCGAGGGTGGCGACCATCAAGCAGCGGCCCAGCAGCCGGTGCTTCCCGGCG GGCTCAGACATGAACTCTGTGTACGAACGCCAAGGAATCGCCGTGATGACGCCCACTGTT CCTGGGAGCCCAAAAGCCCCGTTTCTGGGCATCCCTCGAGGTACGATGCGAAGGCAGAAA TCAATAGACAGCAGAATCTTTCTATCAGGAATAACAGAGGAAGAGCGGCAGTTTCTGGCT CCTCCAATGCTGAAGTTCACCAGAAGCCTGTCCATGCCGGACACCTCTGAGGACATCCCC CCTCCACCGCAGTCTGTGCCCCCGTCCCCACCACCACCTTCCCCAACCACTTACAACTGC CCCAAGTCCCCAACTCCAAGAGTCTACGGGACGATTAAGCCTGCGTTCAATCAGAATTCT GCCGCCAAGGTGTCCCCCGCCACCAGGTCCGACACCGTGGCCACCATGATGAGGGAGAAG GGGATGTACTTCAGGAGAGAGCTGGACCGCTACTCCTTGGACTCTGAAGACCTCTACAGT CGGAATGCCGGCCCGCAAGCCAACTTCCGCAACAAGAGAGGCCAGATGCCAGAAAACCCA TACTCAGAGGTGGGGAAGATCGCCAGCAAAGCCGTCTACGTCCCCGCCAAGCCCGCCAGG CGGAAGGGGATGCTGGTGAAGCAGTCCAACGTGGAGGACAGCCCCGAGAAGACGTGCTCC ATCCCTATCCCGACCATCATCGTGAAGGAGCCGTCCACCAGCAGCAGCGGCAAGAGCAGC CAGGGCAGCAGCATGGAGATCGACCCCCAGGCCCCGGAGCCACCGAGCCAGCTGCGGCCT GACGAAAGCCTGACCGTCAGCAGCCCCTTTGCCGCCGCCATCGCCGGAGCCGTCCGCGAC CGTGAGAAGCGGCTGGAAGCCAGGAGGAACTCCCCGGCCTTCCTCTCCACAGACCTGGGG GATGAGGATGTGGGCCTGGGGCCACCCGCCCCCAGGACGCGGCCCTCCATGTTCCCCGAG GAGGGGGATTTTGCTGACGAGGACAGCGCTGAGCAGCTGTCATCCCCCATGCCGAGTGCC ACGCCCAGGGAGCCCGAAAACCATTTCGTGGGTGGCGCCGAGGCCAGTGCTCCGGGTGAG GCTGGGAGGCCGCTGAATTCCACGTCCAAAGCCCAGGGGCCCGAGAGCAGCCCAGCAGTG CCCTCCGCGAGCAGCGGCACAGCCGGCCCCGGGAATTATGTCCACCCACTCACAGGGCGG CTGCTTGATCCCAGCTCCCCGCTGGCCCTGGCACTCTCCGCAAGGGACCGAGCCATGAAG GAGTCTCAACAGGGACCCAAAGGGGAGGCCCCCAAGGCCGACCTCAACAAACCTCTTTAC ATTGATACCAAAATGCGGCCCAGCCTGGATGCCGGCTTCCCTACGGTCACCAGGCAGAAC ACCCGGGGACCCCTGAGGCGGCAGGAGACGGAGAACAAGTACGAGACCGACCTGGGCCGA GACCGGAAAGGCGATGACAAGAAGAACATGCTGATCGACATCATGGACACGTCCCAGCAG AAGTCGGCTGGCCTGCTGATGGTGCACACCGTGGACGCCACTAAGCTGGACAACGCCCTG CAGGAAGAGGACGAGAAGGCAGAGGTGGAGATGAAGCCAGACAGCTCGCCGTCCGAGGTG CCAGAAGGTGTTTCCGAAACCGAAGGTGCTTTACAGATCTCCGCTGCCCCCGAGCCCACC ACCGTGCCCGGCAGAACCATCGTCGCGGTGGGCTCCATGGAAGAGGCGGTGATTTTGCCA TTCCGCATCCCTCCTCCCCCTCTGGCATCCGTGGACTTGGATGAGGATTTTATTTTTACA GAGCCATTGCCTCCTCCCCTGGAATTTGCAAATAGTTTTGATATCCCCGATGACCGGGCA GCTTCTGTCCCGGCTCTCTCAGACTTAGTGAAGCAGAAGAAAAGCGACACCCCTCAGTCC CCTTCGTTGAACTCCAGCCAACCAACCAACTCTGCAGACAGCAAGAAGCCAGCCAGTCTT TCAAACTGTCTGCCTGCCTCATTCCTGCCACCCCCTGAAAGCTTTGACGCCGTCGCCGAC TCTGGGATCGAGGAGGTGGACAGCCGGAGTAGCAGCGACCACCACCTCGAGACGACCAGC ACTATCTCCACCGTGTCTAGCATCTCCACCCTGTCTTCCGAAGGTGGAGAGAATGTGGAC ACCTGCACAGTCTATGCAGATGGGCAAGCATTTATGGTTGACAAACCCCCAGTACCTCCT AAGCCAAAAATGAAGCCCATCATTCACAAAAGCAATGCACTTTATCAAGACGCGCTCGTG GAAGAAGATGTAGATAGCTTTGTTATCCCCCCGCCCGCTCCCCCGCCCCCGCCGGGCAGT GCCCAGCCTGGGATGGCCAAGGTTCTCCAGCCAAGGACCTCCAAGTTGTGGGGCGACGTC ACAGAGATCAAAAGCCCGATTCTCTCAGGCCCAAAGGCAAACGTTATTAGTGAATTGAAC TCTATCCTACAGCAAATGAACCGAGAGAAATTGGCAAAGCCGGGGGAAGGACTGGATTCA CCAATGGGAGCCAAGTCCGCCAGCCTCGCTCCAAGAAGCCCGGAGATCATGAGCACCATC TCAGGTACACGGAGCACGACGGTCACCTTCACTGTTCGCCCCGGCACCTCCCAGCCCATC ACCCTGCAGAGCCGGCCCCCCGACTATGAAAGCAGGACCTCAGGAACAAGACGTGCCCCA AGCCCTGTGGTCTCGCCAACAGAGATGAACAAAGAGACCCTGCCCGCCCCCCTGTCTGCT GCCACCGCCTCTCCTTCTCCCGCTCTCTCAGATGTCTTTAGCCTTCCAAGCCAGCCCCCT TCTGGGGATCTATTTGGCTTGAACCCAGCGGGACGCAGTAGGTCGCCATCCCCCTCGATA CTGCAACAGCCAATCTCAAATAAGCCTTTTACAACTAAACCTGTCCACCTGTGGACTAAA CCAGATGTGGCCGATTGGCTGGAAAGTCTAAACTTGGGTGAACATAAAGAGGCCTTCATG GACAATGAGATCGATGGCAGTCACTTACCAAACCTGCAGAAGGAGGACCTCATCGATCTT GGGGTAACTCGAGTCGGGCACAGAATGAACATAGAAAGGGCTTTGAAACAGCTGCTGGAC AGATAA |
Restriction Sites | Please inquire |
ACCN | NM_133266 |
ORF Size | 846 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Reference Data | |
RefSeq | NM_133266.1, NP_573573.1 |
RefSeq Size | 2050 |
RefSeq ORF | 846 |
Locus ID | 22941 |
Gene Summary | This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] Transcript Variant: This variant (2) differs in its 5' UTR, lacks a portion of the 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC328058 | SHANK2 (untagged)-Human SH3 and multiple ankyrin repeat domains 2 (SHANK2) transcript variant 2 |
USD 2,550.00 |
|
RC216239 | SHANK2 (Myc-DDK-tagged)-Human SH3 and multiple ankyrin repeat domains 2 (SHANK2), transcript variant 2 |
USD 1,320.00 |
|
RG216239 | SHANK2 (GFP-tagged) - Human SH3 and multiple ankyrin repeat domains 2 (SHANK2), transcript variant 2 |
USD 1,450.00 |
|
RC216239L3 | Lenti-ORF clone of SHANK2 (Myc-DDK-tagged)-Human SH3 and multiple ankyrin repeat domains 2 (SHANK2), transcript variant 2 |
USD 1,520.00 |
|
RC216239L4 | Lenti-ORF clone of SHANK2 (mGFP-tagged)-Human SH3 and multiple ankyrin repeat domains 2 (SHANK2), transcript variant 2 |
USD 1,520.00 |
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