ROR alpha (RORA) (NM_134262) Human Untagged Clone

CAT#: SC305981

RORA (untagged)-Human RAR-related orphan receptor A (RORA), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RORA
• Synonyms: IDDECA; NR1F1; ROR1; ROR2; ROR3; RZR-ALPHA; RZRA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_134262 edited
  GCTTAAATGATGTATTTTGTGATCGCAGCGATGAAAGCTCAAATTGAAATTATTCCATGC
  AAGATCTGTGGAGACAAATCATCAGGAATCCATTATGGTGTCATTACACGTGAAGGCTGC
  AAGGGCTTTTTCAGGAGAAGTCAGCAAAGCAATGCCACCTACTCCTGTCCTCGTCAGAAG
  AACTGTTTGATTGATCGAACCAGTAGAAACCGCTGCCAACACTGTCGATTACAGAAATGC
  CTTGCCGTGGGGATGTCTCGAGATGCTGTAAAATTTGGCCGAATGTCAAAAAAGCAGAGA
  GACAGCTTGTATGCAGAAGTACAGAAACACCGGATGCAGCAGCAGCAGCGCGACCACCAG
  CAGCAGCCTGGAGAGGCTGAGCCGCTGACGCCCACCTACAACATCTCGGCCAACGGGCTG
  ACGGAACTTCACGACGACCTCAGTAACTACATTGACGGGCACACCCCTGAAGGGAGTAAG
  GCAGACTCCGCCGTCAGCAGCTTCTACCTGGACATACAGCCTTCCCCAGACCAGTCAGGT
  CTTGATATCAATGGAATCAAACCAGAACCAATATGTGACTACACACCAGCATCAGGCTTC
  TTTCCCTACTGTTCGTTCACCAACGGCGAGACTTCCCCAACTGTGTCCATGGCAGAATTA
  GAACACCTTGCACAGAATATATCTAAATCGCATCTGGAAACCTGCCAATACTTGAGAGAA
  GAGCTCCAGCAGATAACGTGGCAGACCTTTTTACAGGAAGAAATTGAGAACTATCAAAAC
  AAGCAGCGGGAGGTGATGTGGCAATTGTGTGCCATCAAAATTACAGAAGCTATACAGTAT
  GTGGTGGAGTTTGCCAAACGCATTGATGGATTTATGGAACTGTGTCAAAATGATCAAATT
  GTGCTTCTAAAAGCAGGTTCTCTAGAGGTGGTGTTTATCAGAATGTGCCGTGCCTTTGAC
  TCTCAGAACAACACCGTGTACTTTGATGGGAAGTATGCCAGCCCCGACGTCTTCAGATCC
  TTAGGTTGTGAAGACTTTATTAGCTTTGTGTTTGAATTTGGAAAGAGTTTATGTTCTATG
  CACCTGACTGAAGATGAAGTTGCATTATTTTCTGCATTTGTACTGATGTCAGCAGATCGC
  TCATGGCTGCAAGAAAAGGTAAAAATTGAAAAACTGCAACAGAAAATTCAGCTAGCTCTT
  CAACACGTCCTACAGAAGAATCACCGAGAAGATGGAATACTAACAAAGTTAATATGCAAG
  GTGTCTACATTAAGAGCCTTATGTGGACGACATACAGAAAAGCTAATGGCATTTAAAGCA
  ATATACCCAGACATTGTGCGACTTCATTTTCCTCCATTATACAAGGAGTTGTTCACTTCA
  GAATTTGAGCCAGCAATGCAAATTGATGGGTAAATGTTATCACCTAAGCACTTCTAGAAT
  GTCTGAAGTACAAACATGAAAAACAAACAAAAAAATTAACCGAGACACTTTATATGGCCC
  TGCACA
  
• Restriction Sites: Please inquire
• ACCN: NM_134262
• Insert Size: 1500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and a few SNPs were found in this clone.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_134262.1, NP_599024.1
• RefSeq Size: 1687 bp
• RefSeq ORF: 1407 bp
• Locus ID: 6095
• Cytogenetics: 15q22.2
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Gene Summary: 'The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]'
  Transcript Variant: This variant (4), also called RZR-alpha, contains a different 5' sequence as compared to variant 1. As a result, variant 4 encodes isoform d, whose 11 N-terminal aa differ from the 66 N-terminal aa of isoform a encoded by variant 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.