FREM1 (NM_144966) Human Untagged Clone

CAT#: SC306199

FREM1 (untagged)-Human FRAS1 related extracellular matrix 1 (FREM1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FREM1
• Synonyms: BNAR; C9orf143; C9orf145; C9orf154; MOTA; TILRR; TRIGNO2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_144966 edited
  GACTCTTATCCTGCCCGCCAGTTCCAAGGGTTTCTAACTTTTTGTCTTGGAAAGGAAAAC
  CACTACCTGATTAGAAAAGCACTTGGGAAGCCCATTAATCTTGCCGGCGTTGTCAGGAGT
  GATCAGCGAGTTTTATTAAAAGCCCTGGGATTGCCTGAAAGGCCCCCTTGTCTGACTTTG
  AAATGAAAGGGGCATGTTAAGATCTCGGGGCACATTGTCAGGACCCCTCACCCTGCCCCT
  TGGACTATGAGCTGACCCTCCAGGAGGAAGCACAGAAGCCCTCCTTTGTTAAAGGGATTT
  CGCCGGTGGACAGAGAAGAGTTGGGCCCTGTCAGCATGAACTCTCTGAGTTGGGGGGCTG
  CGAATGCCGTGCTGCTGCTGCTCCTCCTGGCCTGGGCCAGCCCCACCTTCATCAGCATCA
  ACCGCGGGGTGAGGGTGATGAAGGGCCACTCTGCCTTCCTGTCAGGAGATGACCTGAAGT
  TTGCCATCCCTAAAGAGAAAGATGCCTGCAAAGTGGAAGTTGTGATGAATGAGCCAATAA
  CCCAGAGGGTTGGGAAACTCACTCCACAGGTCTTTGACTGCCATTTCCTTCCCAACGAAG
  TCAAGTATGTTCACAATGGTTGTCCAATTCTTGATGAAGACACAGTGAAGCTCAGACTTT
  ACAGATTTACTGAAAGAGATACCTTCATAGAAACTTTTATCCTGTGGGTCTATCTCCTGG
  AACCAGACTGTAACATCATCCATATGAGTAACAATGTGCTGGAGGTGCCTGAATTCAATG
  GCTTGTCCCAAGCGATTGATAAAAATCTGCTCAGATTCGATTATGATAGGATGGCTAGCC
  TGGAATGTACCGTCAGCCTGGACACTGCGAGAACTCGGCTGCCAGCCCATGGCCAGATGG
  TTCTCGGGGAGCCTCGACCAGAAGAACCTCGTGGAGATCAGCCACACAGTTTTTTCCCAG
  AGTCCCAACTGAGAGCAAAACTGAAGTGTCCAGGTGGGAGCTGTACCCCAGGATTAAAGA
  AAATAGGAAGCCTCAAAGTGAGCTGTGAGGAGTTCCTGCTGATGGGCCTTCGTTATCAGC
  ATCTGGATCCCCCTTCACCCAACATTGATTATATCTCCATCCAACTGGACCTCACAGATA
  CCAGGAGCAAAATTGTGTACAAGTCAGAGAGTGCGTGGCTGCCTGTCTATATCAGAGCTG
  GAATTCCGAATCAGATTCCAAAGGCTGCATTCATGGCCGTGTTTATTCTGGAAGTGGATC
  AGTTCATCCTGACCTCCTTGACTACATCAGTTCTGGACTGTGAAGAAGATGAGACCCCTA
  AACCCTTGCTGGTGTTCAACATTACTAAAGCCCCGCTCCAGGGCTATGTGACTCACCTGT
  TGGATCACACCAGACCAATCTCCTCATTCACCTGGAAAGATCTCAGTGACATGCAGATCG
  CCTATCAGCCACCAAACAGCAGCCATTCTGAGAGGAGACATGATGAGGTAGAATTGGAGG
  TATACGACTTCTTCTTTGAAAGGAGTGCACCTATGACAGTCCACATCTCCATCAGAACAG
  CAGATACAAATGCCCCCCGTGTATCCTGGAATACAGGTCTGAGTCTCCTTGAGGGGCAGT
  CTCGAGCCATCACTTGGGAACAGTTTCAGGTTGTCGACAATGACGACATTGGTGCTGTCC
  GGCTAGTCACCGTTGGTGGCCTGCAGCATGGATGGCTGACTTTAAGAGGGGGGAAAGGGT
  TTCTCTTCACCGTGGCTGACCTCCAGGCTGGAGTTGTTCGCTATCATCATGATGACAGCG
  ACTCCACCAAAGACTTCGTGGTCTTCCGGATATTTGATGGCCATCACAGCATCCGTCACA
  AATTCCCCATCAACGTCTTGCCCAAAGATGATAGTCCCCCGTTCCTCATAACCAATGTTG
  TGATTGAACTGGAGGAGGGGCAGACCATCCTGATCCAGGGATCCATGCTGCGAGCTTCAG
  ATGTGGACGCCAGTGATGACTACATCTTCTTCAATATCACAAAGCCTCCACAGGCTGGGG
  AGATCATGAAGAAGCCAGGGCCAGGACTGATAGGCTATCCTGTCCATGGCTTCCTTCAGA
  GGGATTTGTTTAATGGAATCATTTATTATCGTCATTTTGGTGGAGAAATCTTTGAAGATT
  CTTTTCAATTTGTCCTGTGGGACAGCCATGAACCTCCAAATCTTTCAGTGCCACAGGTGG
  CAACAATCCATATAACTCCAGTGGATGACCAGCTTCCAAAAGAGGCTCCTGGAGTTTCTC
  GGCATTTGGTTGTCAAGGAAACTGAGGTGGCCTATATAACTAAGAAACAGCTACATTTTA
  TAGATTCAGAATCATATGACAGGGAGCTGGTCTACACAATAACTACTCCTCCATTTTTCT
  CCTTCAGCCACAGACACTTGGATGCTGGGAAATTATTTATGGTGGACAGCATACCAAAAG
  TAGTTAAGAATCCTACGGCCCTGGAGCTGAGGTCATTCACTCAGCATGCTGTGAACTATA
  TGAAAGTGGCCTACATGCCCCCCATGCAAGACATTGGTCCCCATTGCAGAGATGTCCAGT
  TCACATTTTCTGTCAGTAACCAACATGGCGGTACTTTGCATGGGATCTGCTTTAACATTA
  CAATCCTCCCAGTGGACAATCAAGTTCCTGAGGCGTTCACCAACCCTCTGAAAGTGACTG
  AGGGAGGTCAAAGCATCATCAGCACAGAGCACATTCTAATTTCTGATGCAGATACCAAGC
  TGGACAATATTGACCTCTCCCTGCGGGAATTGCCTCTGCACGGAAGGGTGGAGCTGAATG
  GATTTCCTCTAAATTCAGGGGGCACATTTTCTTGGGGCGATCTCCATACCTTAAAAGTTA
  GGTATCAACATGATGGAACTGAAGTTCTTCAGGATGACCTACTCTTGGAGGTCACCGATG
  GCACAAATTCAGCAGAATTTGTACTACATGTTGAGGTATTCCCTGTCAACGATGAGCCAC
  CAGTCTTAAAGGCTGACCTCATGCCTGTCATGAATTGCTCAGAGGGAGGAGAGGTGGTCA
  TCACCTCTGAATACATTTTTGCTACTGATGTGGACAGCGATAACTTGAAGTTGATGTTTG
  TGATTGCTCGCGAACCTCAGCATGGGGTGGTGAGGAGAGCTGGAGTCACAGTGGATCAGT
  TCTCTCAGAGAGATGTTATCTCAGAGGCCGTGACATACAAACACACAGGTGGCGAGATTG
  GCCTGATGCCTTGTTTTGACACCATTACATTGGTGGTTTCGGATGGAGAGGCTGGCCCTT
  TTGTGAATGGCTGTTGCTACAATGGACCCAATCCATCTGTTCCACTTCATGCGTCCTTTC
  CAGTGTATGATCTCAACATCACGGTATACCCAGTAGACAACCAGCCACCTTCCATTGCAA
  TAGGTCCCGTGTTTGTTGTAGATGAGGGCTGCTCAACAGCCCTTACTGTTAACCATTTGT
  CCGCCACTGACCCTGACACTGCAGCAGATGACTTGGAATTTGTTTTGGTTTCTCCTCCTC
  AGTTTGGCTACCTCGAAAATATACTCCCTTCTGTGGGTTTTGAAAAAAGCAATATTGGCA
  TAAGTATAGATTCATTTCAGTGGAAAGACATGAACGCTTTTCACATTAACTATGTGCAGT
  CCAGGCATCTGAGGATAGAACCAACTGCCGACCAGTTCACGGTGTACGTCACAGATGGGA
  AGCATCACTCCTTGGAGATACCATTTTCTATTATAATCAACCCCACAAATGATGAAGCTC
  CTGACTTTGTAGTGCAGAATATTACTGTGTGTGAGGGTCAGATGAAAGAGCTGGACTCTT
  CCATCATCAGCGCTGTGGACCTGGACATTCCCCAGGATGCCCTGCTGTTCAGCATCACTC
  AAAAGCCACGCCATGGCCTCCTCATCGATAGGGGGTTTAGCAAAGACTTCTCTGAGAATA
  AGCAGCCAGCCAACCCTCACCAGAAACATGCACCTGTTCACAGCTTTTCCATGGAACTCC
  TCAAGACTGGAATGAGGTTGACGTACATGCATGATGACTCAGAGAGCCTTGCTGATGATT
  TTACAATCCAATTGTCAGATGGGAAACATAAGATACTTAAAACCATTTCAGTAGAGGTCA
  TCCCAGTTAATGATGAAAAACCAATGCTGAGCAAGAAGGCTGAAATTGCAATGAATATGG
  GTGAAACTCGTATTATTTCCAGTGCTATTCTTTCAGCCATAGATGAAGACTCACCCAGGG
  AGAAGATTTACTATGTATTTGAAAGGCTTCCCCAAAATGGGCAACTTCAGCTTAAGATAG
  GGAGGGACTGGGTTCCTCTCTCCCCTGGCATGAAATGCACTCAGGAGGAAGTGGATCTGA
  ACTTGCTGAGATACACACACACCGGGGCAATGGATTCCCAGAATCAAGATAGCTTCACCT
  TCTACCTTTGGGATGGCAACAACAGGTCCCCTGCTCTTGACTGTCAAATCACCATCAAGG
  ACATGGAAAAAGGTGATATTGTCATCCTTACAAAACCACTCGTGGTGTCTAAAGGTGATA
  GAGGTTTCTTAACAACCAGCACGCTCCTGGCTGTGGACGGAACAGACAAGCCTGAGGAAC
  TGCTCTATGTCATCACCTCCCCTCCGCGATATGGCCAGATCGAATATGTTCACTATCCTG
  GAGTTCCCATTACAAACTTCAGCCAAATGGATGTAGTGGGGCAGACAGTTTGCTATGTAC
  ACAAGAGCAAGGTGACTGTCTCCAGTGACAGATTCAGATTCATCATCAGCAATGGACTGC
  GGACCGAGCACGGGGTGTTTGAGATCACACTGGAGACTGTGGACAGAGCCCTGCCTGTGG
  TAACCAGGAACAAGGGGTTGAGACTGGCCCAAGGGGCCGTGGGCCTGCTTTCCCCTGACC
  TCCTTCAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGC
  TCCCCCAGCATGGCCAGCTCTACCTGTGGGGGACAGGGCTACTTCAACACAATTTCACCC
  AGCAGGATGTGGACAGCAAGAATGTGGCCTATCGGCACTCAGGAGGGGACTCCCAGACTG
  ACTGCTTTACTTTCATGGCCACAGACGGGACAAACCAAGGCTTTATTGTGAATGGGAGAG
  TGTGGGAAGAACCTGTTTTATTCACCATTCAGGTAGACCAATTGGACAAAACAGCTCCTC
  GTATCACACTCTTGCATTCCCCTTCTCAAGTGGGGCTCCTGAAAAATGGCTGCTACGGGA
  TTTACATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCA
  TCTTTAAAATTCTACAAGGCCCAAAACATGGACATCTGGAGAACACAACAACAGGTGAAT
  TTATCCATGAGAAATTTAGCCAAAAGGACTTAAACAGTAAGACTATTCTTTACATCATAA
  ACCCATCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGA
  ACTCGGCCACTCCTCAAATTTTGGAACTGAAGTGGTCTCATATTGAATGGTCACAGACCG
  AATATGAAGTCTGTGAGAATGTGGGTTTGTTGCCCTTGGAAATTATCAGAAGGGGATATT
  CCATGGACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAG
  ATTTCACCGTGATTCCATCTAAACTGATTCAGTTTGACCCAGGAATGTCAACTAAGATGT
  GGAATATAGCAATTACCTATGACGGATTAGAGGAAGATGATGAGGTCTTTGAAGTAATTC
  TGAACTCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGG
  ACTCAAAAGGAGGACAATGCCATCCTTCATATTCCTCCAACCAAAGCAAGCACAGCACAT
  GGGAGAAGGGCATTTGGCATCTGCTGCCCCCAGGGTCTTCCTCATCCACCACTTCTGGTT
  CCTTTCATCTGGAAAGAAGACCTCTTCCATCTTCCATGCAGCTAGCAGTCATCAGGGGAG
  ACACCCTGCGGGGCTTTGATTCTACAGATCTTTCTCAAAGGAAGCTTAGGACCCGTGGGA
  ATGGCAAAACAGTTCGTCCATCCTCTGTTTATAGAAATGGAACAGACATCATCTATAATT
  ATCATGGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGG
  CCAAAGTATCCATCATTAGTCAGCCACAAAAGACAATCAAAGTGGCAGAACTGCCTCAAG
  CAGATAAGGTGGAATCCACAACTGACTCACACTTCCCCAGACAGGACCAGTTGCCCTCAT
  TTCCAAAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGA
  AGCTGTATCAGTGCAATGGGATCGCCTGGAAAGCCTGGAGTCCCCAAACCAAGGATGTGG
  AAGACAAATCCTGTCCAGCCGGGTGGCACCAGCACTCAGGCTACTGTCACATCTTGATCA
  CAGAGCAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCA
  ACCTTGTAACTGTATTCTCCAGGCAGCACATGCGGTGGCTCTGGGACATTGGTGGGAGAA
  AGTCCTTTTGGATAGGTTTGAACGACCAAGTGCATGCTGGCCACTGGGAGTGGATCGGTG
  GTGAACCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCCACGCTCCAAGCTTGGAA
  AGAGCTGTGTTTTGGTTCAAAGACAAGGGAAATGGCAAACAAAAGACTGTAGGAGAGCCA
  AACCTCATAATTATGTGTGTTCCAGAAAACTCTAAATATAACAGACCCTACAGGGGGCCA
  CCTGGAGTTTGTCACCTATTTATTCACAGGATCTGTGAATATTGCTCCATAGAAAACAAA
  TTGTTATGATTGAGTGGGTATACCTTTGTGATTCTGTCTAGTGAAAATGGGACATTTTTA
  ATAGTGCCAGAAAGATTGATAAATAAATATTTTTTACAAGATAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_144966
• ORF Size: 4008 bp
• Insert Size: 7400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found three SNPs within the protein associated with this reference, NM_144966.4.

Reference Data

• RefSeq: NM_144966.3, NP_659403.3
• RefSeq Size: 6200
• RefSeq ORF: 4008
• Locus ID: 158326
• Protein Families: Protease, Transmembrane
• Gene Summary: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation. [provided by RefSeq, Apr 2011]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.