PPIL5 (LRR1) (NM_152329) Human Untagged Clone

CAT#: SC306366

LRR1 (untagged)-Human leucine rich repeat protein 1 (LRR1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LRR1
• Synonyms: 4-1BBLRR; LRR-1; PPIL5
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_152329, the custom clone sequence may differ by one or more nucleotides
  ATGAAGCTACACTGTGAGGTGGAGGTGATCAGCCGGCACTTGCCCGCCTTGGGGCTTAGG
  AACCGGGGCAAGGGCGTCCGAGCCGTGTTGAGCCTCTGTCAGCAGACTTCCAGGAGTCAG
  CCGCCGGTCCGAGCCTTCCTGCTCATCTCCACCCTGAAGGACAAGCGCGGGACCCGCTAT
  GAGCTAAGGGAGAACATTGAGCAATTCTTCACCAAATTTGTAGATGAGGGGAAAGCCACT
  GTTCGGTTAAAGGAGCCTCCTGTGGATATCTGTCTAAGTAAGGCCATTTCCAGCAGTTTA
  AAAGGTTTCCTTTCAGCTATGAGACTGGCTCATAGAGGCTGTAATGTTGATACACCAGTT
  TCAACGCTCACACCAGTGAAGACTTCAGAATTTGAAAACTTTAAAACTAAAATGGTTATC
  ACATCCAAAAAAGACTATCCTCTAAGTAAGAATTTTCCATATTCCTTGGAACATCTTCAG
  ACTTCTTACTGTGGGCTTGTCCGAGTTGATATGCGTATGCTTTGCTTAAAAAGCCTTAGG
  AAATTAGACTTGAGTCACAACCATATAAAAAAGCTTCCAGCTACAATTGGAGACCTCATA
  CACCTTCAAGAACTTAACCTGAATGACAATCACTTGGAGTCATTTAGTGTAGCCTTGTGT
  CATTCTACACTCCAGAAGTCACTTCGGAGTTTGGACCTCAGCAAGAACAAAATCAAGGCA
  CTCCCTGTGCAGTTTTGCCAGCTCCAGGAACTTAAGAATTTAAAACTTGACGATAATGAA
  TTGATTCAATTTCCTTGCAAGATAGGACAACTAATAAACCTTCGCTTTTTGTCAGCAGCT
  CGAAATAAGCTTCCATTTTTGCCTAGTGAATTTAGAAATTTATCCCTTGAATACTTGGAT
  CTTTTTGGAAATACTTTTGAACAACCAAAAGTCCTTCCAGTAATAAAGCTGCAAGCACCA
  TTAACTTTATTGGAATCTTCTGCACGAACCATATTACATAATAGGATTCCATATGGCTCT
  CATATCATTCCATTCCATCTCTGCCAAGATTTGGATACCGCAAAAATTTGTGTTTGTGGA
  AGATTCTGTCTGAACTCTTTCATTCAAGGAACTACTACCATGAATCTGCATTCTGTTGCC
  CACACTGTGGTCTTAGTAGATAATTTGGGTGGTACTGAAGCACCTATTATCTCTTATTTC
  TGTTCTCTAGGCTGTTATGTTAATTCCTCTGATATGTTAAAGTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_152329
• ORF Size: 1245 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_152329.3, NP_689542.2
• RefSeq Size: 1760
• RefSeq ORF: 1245
• Locus ID: 122769
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
  Transcript Variant: This variant (1) encodes the longest isoform (1). Isoform 1 has also been named LRR-1a.