WDR81 (NM_152348) Human Untagged Clone

CAT#: SC306372

WDR81 (untagged)-Human WD repeat domain 81 (WDR81), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WDR81
• Synonyms: CAMRQ2; HYC3; PPP1R166; SORF-2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_152348, the custom clone sequence may differ by one or more nucleotides
  ATGGATGGGGAGCCTCCTGCCTCCTCGGGCCTGGGGCTCCCAGACTACACGTCTGGCGTC
  AGCTTCCACGACCAGGCTGACCTCCCTGAGACAGAGGACTTCCAAGCCGGGCTCTATGTG
  ACTGAGTCTCCCCAGCCCCAGGAGGCTGAGGCTGTGAGCCTGGGCCGGCTGAGTGACAAG
  AGCAGCACCAGCGAGACCTCCCTGGGTGAGGAGCGGGCTCCAGACGAGGGGGGTGCCCCC
  GTGGACAAGAGCAGCCTTCGATCAGGTGACAGCAGCCAGGACTTGAAGCAAAGCGAGGGC
  TCCGAGGAGGAAGAGGAGGAGGAGGACAGCTGCGTGGTGCTAGAGGAGGAGGAGGGGGAG
  CAGGAGGAGGTCACCGGGGCATCTGAGCTCACTCTGTCTGACACGGTGCTGTCCATGGAG
  ACGGTTGTGGCCGGCGGCAGTGGGGGAGATGGAGAAGAAGAGGAGGAGGCACTGCCTGAG
  CAGTCAGAAGGCAAAGAACAGAAGATCCTCCTTGATACAGCCTGCAAGATGGTCCGCTGG
  CTGTCTGCCAAGCTCGGCCCCACAGTGGCCTCTCGCCACGTGGCCCGGAACCTGCTCCGC
  CTGCTGACGTCTTGTTATGTTGGACCCACTCGGCAGCAGTTCACAGTGAGCAGTGGCGAG
  AGCCCACCGCTGAGCGCCGGCAACATCTACCAGAAGAGGCCGGTCCTGGGCGACATCGTG
  TCAGGGCCTGTGCTCAGCTGCCTCCTCCACATCGCCCGCCTGTATGGGGAGCCTGTCCTC
  ACCTACCAGTACCTGCCCTACATCAGCTACCTGGTGGCCCCAGGGAGTGCCTCAGGCCCC
  AGCCGACTGAACAGCCGTAAGGAGGCGGGGCTGCTGGCCGCGGTGACGCTGACTCAGAAG
  ATCATCGTGTACCTCTCAGACACCACACTCATGGACATCCTGCCCCGGATCAGCCATGAG
  GTCCTGCTGCCCGTGCTCAGCTTCCTCACCTCCCTCGTCACGGGGTTCCCAAGTGGGGCC
  CAGGCTCGGACCATCCTGTGTGTGAAAACCATCAGCCTCATCGCCCTCATCTGCCTGCGC
  ATTGGACAGGAGATGGTCCAGCAGCACCTGAGCGAGCCCGTGGCCACCTTTTTCCAGGTC
  TTCTCTCAGCTGCATGAGCTTCGGCAACAGGATCTGAAGCTGGACCCTGCGGGCCGTGGT
  GAGGGCCAGCTGCCACAGGTGGTCTTCTCTGATGGGCAGCAGCGGCCCGTGGACCCCGCC
  CTGCTGGACGAGCTGCAGAAGGTGTTCACCCTGGAGATGGCATACACAATCTACGTGCCC
  TTCTCCTGCCTGTTGGGTGACATCATCCGGAAAATCATCCCCAACCACGAGCTGGTTGGG
  GAGCTGGCGGCGCTGTACTTGGAGAGCATCAGCCCCAGCAGTCGCAACCCTGCCAGCGTG
  GAGCCCACCATGCCCGGCACCGGGCCCGAGTGGGACCCCCATGGTGGGGGCTGCCCTCAG
  GATGACGGCCACTCAGGGACCTTTGGGAGCGTCCTGGTGGGGAACCGCATTCAGATCCCC
  AATGACTCTCGGCCTGAGAACCCCGGACCACTGGGCCCCATCTCGGGGGTGGGTGGCGGG
  GGCCTGGGCAGCGGGAGCGACGACAACGCCCTGAAGCAGGAGCTGCCGCGGAGCGTGCAC
  GGGCTGAGCGGAAACTGGCTGGCGTACTGGCAGTACGAGATCGGCGTGAGCCAGCAGGAT
  GCCCACTTTCACTTCCACCAGATCCGCCTGCAGAGCTTCCCGGGCCACTCGGGGGCCGTC
  AAGTGCGTGGCACCCCTAAGCAGCGAGGACTTCTTCCTGAGCGGCAGCAAGGATCGTACC
  GTGCGCCTCTGGCCGCTGTACAACTACGGCGACGGGACCAGCGAGACGGCCCCACGCCTC
  GTCTACACCCAGCACCGCAAGAGCGTCTTCTTCGTGGGCCAGCTTGAGGCCCCGCAGCAC
  GTGGTGAGCTGTGACGGGGCTGTGCACGTCTGGGACCCCTTCACAGGGAAGACCCTTCGC
  ACAGTGGAGCCGCTGGACAGCCGGGTGCCCCTGACTGCGGTGGCTGTCATGCCCGCCCCC
  CACACCAGCATCACCATGGCCAGCTCTGACTCTACCCTGCGCTTTGTGGACTGCAGGAAG
  CCTGGTCTGCAGCACGAGTTCCGACTGGGCGGTGGGCTGAACCCTGGGCTTGTCCGTGCC
  CTGGCCATCAGCCCCAGTGGCCGTAGTGTCGTGGCCGGCTTCTCCTCAGGCTTCATGGTG
  CTCCTGGACACCCGCACAGGCCTGGTTCTGCGAGGCTGGCCAGCCCACGAGGGGGACATT
  CTGCAGATCAAGGCGGTGGAGGGCAGCGTCCTGGTCAGCTCCTCCTCTGACCATTCCTTG
  ACCGTCTGGAAGGAGCTGGAGCAGAAGCCCACCCATCACTACAAGTCAGCATCCGACCCC
  ATCCACACCTTTGACCTGTACGGCAGCGAGGTGGTCACTGGCACCGTGTCCAACAAGATT
  GGCGTCTGCTCCCTGCTTGAGCCACCCTCGCAGGCCACCACGAAGCTCAGCTCTGAGAAC
  TTCCGCGGCACGCTCACCAGCCTGGCCTTGCTGCCCACTAAACGCCACCTCCTGCTGGGC
  TCAGACAACGGGGTTATCCGCCTCCTGGCATAG
  
• Restriction Sites: Please inquire
• ACCN: NM_152348
• ORF Size: 2673 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_152348.1, NP_689561.1
• RefSeq Size: 3789
• RefSeq ORF: 2673
• Locus ID: 124997
• Gene Summary: This gene encodes a multi-domain transmembrane protein which is predominantly expressed in the brain and is thought to play a role in endolysosomal trafficking. Mutations in this gene are associated with an autosomal recessive form of a syndrome exhibiting cerebellar ataxia, cognitive disability, and disequilibrium (CAMRQ2). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1.