HIF3 alpha (HIF3A) (NM_152794) Human Untagged Clone

CAT#: SC306504

HIF3A (untagged)-Human hypoxia inducible factor 3, alpha subunit (HIF3A), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HIF3A
• Synonyms: bHLHe17; HIF-3A; HIF3-alpha-1; IPAS; MOP7; PASD7
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_152794 edited
  ATGGACTGGCAAGACCACAGGTCGACCACGGAGCTGCGCAAGGAAAAGTCCCGGGATGCG
  GCCCGCAGCCGGCGCAGCCAGGAGACCGAGGTGCTGTACCAGCTGGCTCACACGCTGCCC
  TTCGCCCGCGGCGTCAGCGCCCACCTGGACAAGGCCTCTATCATGCGCCTCACCATCAGC
  TACCTGCGCATGCACCGCCTCTGCGCCGCAGGGGAGTGGAACCAGGTGGGAGCAGGGGGA
  GAACCACTGGATGCCTGCTACCTGAAGGCCCTGGAGGGCTTCGTCATGGTGCTCACCGCC
  GAGGGAGACATGGCTTACCTGTCGGAGAATGTCAGCAAACACCTGGGCCTCAGTCAGCTG
  GAGCTCATTGGACACAGCATCTTTGATTTCATCCACCCCTGTGACCAAGAGGAGCTTCAG
  GACGCCCTGACCCCCCAGCAGACCCTGTCCAGGAGGAAGGTGGAGGCCCCCACGGAGCGG
  TGCTTCTCCTTGCGCATGAAGAGTACGCTCACCAGCCGCGGGCGCACCCTCAACCTCAAG
  GCGGCCACCTGGAAGGTGCTGAACTGCTCTGGACATATGAGGGCCTACAAGCCACCTGCG
  CAGACTTCTCCAGCTGGGAGCCCTGACTCAGAGCCCCCGCTGCAGTGCCTGGTGCTCATC
  TGCGAAGCCATCCCCCACCCAGGCAGCCTGGAGCCCCCACTGGGCCGAGGGGCCTTCCTC
  AGCCGCCACAGCCTGGACATGAAGTTCACCTACTGTGACGACAGGATTGCAGAAGTGGCT
  GGCTATAGTCCCGATGACCTGATCGGCTGTTCCGCCTACGAGTACATCCACGCGCTGGAC
  TCCGATGCGGTCAGCAAGAGCATCCACACCTTGCTGAGCAAGGGCCAGGCAGTAACAGGG
  CAGTATCGCTTCCTGGCCCGGAGTGGTGGCTACCTGTGGACCCAGACCCAGGCCACAGTG
  GTGTCAGGGGGACGGGGCCCCCAGTCGGAGAGTATCGTCTGTGTCCATTTTTTAATCAGC
  CAGGTGGAAGAGACCGGAGTGGTGCTGTCCCTGGAGCAAACGGAGCAACACTCTCGCAGA
  CCCATTCAGCGGGGCGCCCCCTCTCAGAAGGACACCCCTAACCCTGGGGACAGCCTTGAC
  ACCCCTGGCCCCCGGATCCTTGCCTTCCTGCACCCGCCTTCCCTGAGCGAGGCTGCCCTG
  GCCGCTGACCCCCGCCGTTTCTGCAGCCCTGACCTCCGTCGCCTCCTGGGACCCATCCTG
  GATGGGGCTTCAGTAGCAGCCACTCCCAGCACCCCGCTGGCCACACGGCACCCCCAAAGT
  CCTCTTTCGGCTGATCTCCCAGATGAACTACCTGTGGGCACCGAGAATGTGCACAGACTC
  TTCACCTCCGGGAAAGACACTGAGGCAGTGGAGACAGATTTAGATATAGCTCAGGATGCT
  GATGCTCTGGATTTGGAGATGCTGGCCCCCTACATCTCCATGGATGATGACTTCCAGCTC
  AACGCCAGCGAGCAGCTACCCAGGGCCTACCACAGACCTCTGGGGGCTGTCCCCCGGCCC
  CGTGCTCGGAGCTTCCATGGCCTGTCACCTCCAGCCCTTGAGCCCTCCCTGCTACCCCGC
  TGGGGGAGTGACCCCCGGCTGAGCTGCTCCAGCCCTTCCAGAGGGGACCCCTCAGCATCC
  TCTCCCATGGCTGGGGCTCGGAAGAGGACCCTGGCCCAGAGCTCAGAGGACGAGGACGAG
  GGAGTGGAGCTGCTGGGAGTGAGACCTCCCAAAAGGTCCCCCAGCCCAGAACACGAAAAC
  TTTCTGCTCTTTCCTCTCAGCCTGAGTTTCCTTCTGACAGGAGGACCAGCCCCAGGGAGC
  CTGCAGGACCCCAGCACCCCACTCCTGAACCTGAATGAGCCCCTGGGCCTGGGCCCCTCA
  CTGCTCTCTCCGTACTCAGACGAGGACACTACCCAGCCCGGGGGCCCCTTCCAGCCAAGG
  GCAGGCTCAGCCCAGGCTGACTGAGCCGGCTCCTCTCCCCATCTGCCTTCTCCTCCCCCA
  GAAAGGACCTCAACCACACTCCACGCCGGCAGCCAACGCACAGGATGGGGGCGCCAGGAG
  AGGGGCCCCTCTCTCCTCTATGTACCCCCTGCCCACCTCGGGCCTACCTCAGCCCTCACC
  CCTCTGCCTGCTCCCAATCTGGGGGCTCTCTGGGGTGGTCTCAGCTCAGTGACCTCTGGG
  AGGTGGTCCCTGGCCCCCTCCTCCTTCTCTCAGGATTTCTCTTGGGGTTCTCAATACTTG
  GTTACCTCATTATCCCTTTCTCTGCCTCTCTTGGCTTTATTTTGGGGAATCAGGGGTGAG
  GAGGGTTGGGGGGGTCATATCTGTGTTTCCAGGTTCTGGGGAGAACAATGATCCACGGGT
  CAACGTGATCACATTTCCTTCTAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_152794
• ORF Size: 2004 bp
• Insert Size: 2500
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_152794.1, NP_690007.1
• RefSeq Size: 2717
• RefSeq ORF: 2004
• Locus ID: 64344
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
  Transcript Variant: This variant (1) differs in the 5' UTR and 5' coding region, compared to variant 3. The resulting isoform (a) has a distinct and shorter N-terminus, compared to isoform c. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.