GGT6 (NM_153338) Human Untagged Clone

CAT#: SC306589

GGT6 (untagged)-Human gamma-glutamyltransferase 6 (GGT6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GGT6
• Synonyms: FLJ25990; FLJ90165
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_153338, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGCGGGCAGAAGAGCCCGTGGTCTATCAGAAGCTGCTGCCCTGGGAGCCAAGCTTGGAGTCGGAGG
  AGGAAGTGGAGGAGGAGGAGACATCAGAGGCGCTGGTTCTAAACCCCCGGAGGCACCAGGACTCTTCCAG
  GAACAAGGCTGGCGGGCTGCCCGGAACCTGGGCCCGTGTAGTGGCAGCCCTGCTGCTGCTGGCTGTTGGC
  TGCTCCCTGGCTGTGAGGCAGCTCCAGAATCAGGGCAGGTCGACAGGAAGCTTGGGCTCTGTGGCCCCTC
  CACCCGGCGGACACTCCCACGGCCCTGGCGTATACCACCACGGTGCCATCATCAGCCCTGCAGGTGCCAT
  GTTTTGGGGCCTCTTCCACGATAGCTCCTCAGGCAATTCCACGGCCCTGACATCAGGCCCAGCACAGACC
  CTGGCCCCCGGCCTGGGGCTGCCCGCGGCTCTGCCCACCCTGCACCTGCTGCATGCACGCTTCGGCCGCC
  TGCCCTGGCCACGCCTGCTAGTGGGCCCCACCACGCTGGCTCAGGAGGGCTTCCTGGTGGACACACCCCT
  GGCAAGGGCTCTGGTGGCTCGGGGCACAGAAGGCCTCTGTCCACTACTTTGCCATGCTGATGGGACACCC
  CTGGGCGCTGGGGCCCGAGCCACCAACCCACAACTGGCAGCTGTGCTTCGCAGCGCAGCCCTCGCTCCCA
  CCTCAGACCTTGCTGGGGATGCTCTACTGAGTCTACTGGCGGGAGACCTGGGGGTGGAGGTGCCCTCGGC
  TGTGCCCAGGCCCACTTTGGAACCAGCAGAGCAGCTACCTGTGCCCCAGGGCATCCTGTTCACCACCCCC
  AGTCCCTCAGCTGGCCCAGAACTGCTGGCACTGTTGGAGGCAGCCCTGCGCTCCGGGGCGCCCATCCCTG
  ACCCCTGCCCACCGTTCCTGCAGACTGCTGTGAGCCCCGAGAGCAGTGCCCTGGCCGCCGTGGACAGCAG
  CGGCTCTGTGCTCCTTCTCACCTCCTCGCTCAACTGCTCCTTTGGCTCTGCACACCTGTCCCCAAGCACT
  GGGGTTCTGCTCAGCAACCTGGTGGCCAAGTCTACCACTAGTGCCTGGGCCTGCCCCCTCATCCTCCGTG
  GCAGCCTGGATGACACAGAGGCTGATGTGTTGGGGCTTGTGGCTTCAGGGACCCCTGATGTGGCCAGGGC
  CATGACTCACACCCTACTCAGGCATCTGGCAGCAAGGCCCCCTACCCAGGCCCAGCACCAGCATCAGGGT
  CAGCAAGAACCAACAGAGCATCCCAGCACTTGTGGCCAAGGGACCCTGCTCCAGGTGGCAGCCCACACAG
  AGCACGCCCATGTCTCCAGTGTCCCCCATGCCTGCTGCCCCTTCCAGGGGTTCTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_153338
• ORF Size: 1386 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_153338.3, NP_699169.2
• RefSeq Size: 2556
• RefSeq ORF: 1386
• Locus ID: 124975
• Protein Pathways: Arachidonic acid metabolism, Cyanoamino acid metabolism, Glutathione metabolism, Metabolic pathways, Selenoamino acid metabolism, Taurine and hypotaurine metabolism
• Gene Summary: GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]). [supplied by OMIM, Oct 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 3. It encodes isoform b, which is shorter than isoform c.