IL22 RA2 (IL22RA2) (NM_181309) Human Untagged Clone

CAT#: SC307270

IL22RA2 (untagged)-Human interleukin 22 receptor, alpha 2 (IL22RA2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL22RA2
• Synonyms: CRF2-10; CRF2-S1; CRF2X; IL-22BP; IL-22R-alpha-2; IL-22RA2; ZCYTOR16
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_181309 edited
  TTTCCTCTTTGGTCCTGAGCTGGTTAAAAGGAACACTGGTTGCCTGAACAGTCACACTTG
  CAACCATGATGCCTAAACATTGCTTTCTAGGCTTCCTCATCAGTTTCTTCCTTACTGGTG
  TAGCAGGAACTCAGTCAACGCATGAGTCTCTGAAGCCTCAGAGGGTACAATTTCAGTCCC
  GAAATTTTCACAACATTTTGCAATGGCAGCCTGGGAGGGCACTTACTGGCAACAGCAGTG
  TCTATTTTGTGCAGTACAAAATATATGGACAGAGACAATGGAAAAATAAAGAAGACTGTT
  GGGGTACTCAAGAACTCTCTTGTGACCTTACCAGTGAAACCTCAGACATACAGGAACCTT
  ATTACGGGAGGGTGAGGGCGGCCTCGGCTGGGAGCTACTCAGAATGGAGCATGACGCCGC
  GGTTCACTCCCTGGTGGGAAACAAAAATAGATCCTCCAGTCATGAATATAACCCAAGTCA
  ATGGCTCTTTGTTGGTAATTCTCCATGCTCCAAATTTACCATATAGATACCAAAAGGAAA
  AAAATGTATCTATAGAAGATTACTATGAACTACTATACCGAGTTTTTATAATTAACAATT
  CACTAGAAAAGGAGCAAAAGGTTTATGAAGGGGCTCACAGAGCGGTTGAAATTGAAGCTC
  TAACACCACACTCCAGCTACTGTGTAGTGGCTGAAATATATCAGCCCATGTTAGACAGAA
  GAAGTCAGAGAAGTGAAGAGAGATGTGTGGAAATTCCATGACTTGTGGAATTTGGCATTC
  AGCAATGTGGAAATTCTAAAGCTCCCTGAGAACAGGATGACTCGTGTTTGAAGGATCTTA
  TTTAAAATTGTTTTTGTATTTTCTTAAAGCAATATTCACTGTTACACCTTGGGGACTTCT
  TTGTTTATCCATTCTTTTATCCTTTATATTTCATTTGTAAACTATATTTGAACGACATTC
  CCCCCGAAAAATTGAAATGTAAAGATGAGGCAGAGAATAAAGTGTTCTATGAAATTCAGA
  ACTTTATTTCTGAATGTAACATCCCTAATAACAACCTTCATTCTTCTAATACAGCAAAAT
  AAAAATTTAACAACCAAGGAATAGTATTTAAGAAAATGTTGAAATAATTTTTTTAAAATA
  GCATTACAGACTGAGGCGGTCCTGAAGCAATGGTTTTTCACTCTCTTATTGAGCCAATTA
  AATTGACATTGCTTTGACAATTTAAAACTTCTATAAAGGTGAATATTTTTCATACATTTC
  TATTTTATATGAATATACTTTTTATATATTTATTATTATTAAATATTTCTACTTAATGAA
  TCAAAATTTTGTTTTAAAGTCTACTTTATGTAAATAAGAACAGGTTTTGGGGAAAAAAAT
  CTTATGATTTCTGGATTGATATCTGAATTAAAACTATCAACAACAAGGAAGTCTACTCTG
  TACAATTGTCCCTCATTTAAAAGATATATTAAGCTTTTCTTTTCTGTTTGTTTTTGTTTT
  GTTTAGTTTTTAATCCTGTCTTAGAAGAACTTATCTTTATTCTCAAAATTAAATGTAATT
  TTTTTAGTGACAAAGAAGAAAGGAAACCTCATTACTCAATCCTTCTGGCCAAGAGTGTCT
  TGCTTGTGGCGC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_181309 unedited
  TTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGCCCTTTCCTCTTTGGTCCTGA
  GCTGGTTAAAAGGAACACTGGTTGCCTGAACAGTCACACTTGCAACCATGATGCCTAAAC
  ATTGCTTTCTAGGCTTCCTCATCAGTTTCTTCCTTACTGGTGTAGCAGGAACTCAGTCAA
  CGCATGAGTCTCTGAAGCCTCAGAGGGTACAATTTCAGTCCCGAAATTTTCACAACATTT
  TGCAATGGCAGCCTGGGAGGGCACTTACTGGCAACAGCAGTGTCTATTTTGTGCAGTACA
  AAATATATGGACAGAGACAATGGAAAAATAAAGAAGACTGTTGGGGTACTCAAGAACTCT
  CTTGTGACCTTACCAGTGAAACCTCAGACATACAGGAACCTTATTACGGGAGGGTGAGGG
  CGGCCTCGGCTGGGAGCTACTCAGAATGGAGCATGACGCCGCGGTTCACTCCCTGGTGGG
  AAACAAAAATAGATCCTCCAGTCATGAATATAACCCAAGTCAATGGCTCTTTGTTGGTAA
  TTCTCCATGCTCCAAATTTACCATATAGATACCAAAAGGAAAAAAATGTATCTATAGAAG
  ATTACTATGAACTACTATACCGAGTTTTTATAATTAACAATTCACTAGAAAAGGAGCANA
  AGGGTTATGAAGGGGCTCACAGAGCGGTTGAAATTGAAGCTCTAACACCACACTCCAGCT
  ACTGTGTAGTGGCTGAAATATATCAGCCCATGTTAGACAGAAGAAGTCAGAGAAGTGAAG
  AGAGATGTGTGGAAAATTCATTGACTGTGGGAATTGGCATTCAGCATGGTGGAATTCTAA
  AGCTCCCTGANAACAAGATGA
  
• Restriction Sites: Please inquire
• ACCN: NM_181309
• ORF Size: 696 bp
• Insert Size: 1600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_181309.1, NP_851826.1
• RefSeq Size: 2814
• RefSeq ORF: 696
• Locus ID: 116379
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region, compared to variant 1. The resulting isoform (2) is shorter, compared to isoform 1.