CREM (NM_182771) Human Untagged Clone
CAT#: SC307512
CREM (untagged)-Human cAMP responsive element modulator (CREM), transcript variant 15
"NM_182771" in other vectors (6)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | CREM |
Synonyms | CREM-2; hCREM-2; ICER |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_182771 edited
AGCTACGGGTCAGAGCTAGTCCACTAGGTGCTAATCAAATGCTGTGTTACAACACTGTGA GGTTTTCCCAGTTATAAGTGTCACTATTAGGGTTTTTTTTAATTGCAAAGCCAAATAAGG CTGTCAATTGCATCATCTTACCTTATTTCTTCAGATTAAGTACTGTTTATAGTGGGATTT TTGGTGGATGTGGTGGCATCAGCATAATCTATGTTTCAGGCGTCCTATAGAAGAGGATTA TTCTTCAGGGGATGTGGAAGAAAAGGTAGCAGCAATTGCAGAGACAGATGAATCTGCAGA ATCAGAAGGTGTAATTGATTCTCATAAACGTAGAGAAATCCTTTCACGAAGACCCTCTTA TAGGAAAATACTGAATGAACTGTCCTCTGATGTGCCTGGTGTTCCCAAGATTGAAGAAGA GAGATCAGAGGAAGAAGGAACACCACCTAGTATTGCTACCATGGCAGTACCAACTAGCAT ATATCAGACTAGCACGGGGCAATACATTGCTATAGCCCAAGGTGGAACAATCCAGATTTC TAACCCAGGATCTGATGGTGTTCAGGGACTGCAGGCATTAACAATGACAAATTCAGGAGC TCCTCCACCAGGTGCTACAATTGTACAGTACGCAGCACAATCAGCTGATGGCACACAGCA GTTCTTTGTCCCAGGCAGCCAGGTTGTTGTTCAAGCTGCCACTGGTGACATGCCAACTTA CCAGATCCGAGCTCCTACTGCTGCTTTGCCACAGGGAGTGGTGATGGCTGCATCGCCCGG AAGTTTGCACAGTCCCCAGCAGCTGGCAGAAGAAGCAACACGCAAACGAGAGCTGAGGCT AATGAAAAACAGGGAAGCTGCCAAAGAATGTCGACGTCGAAAGAAAGAATATGTAAAATG TCTGGAGAGCCGAGTTGCAGTGCTGGAAGTCCAGAACAAGAAGCTTATAGAGGAACTTGA AACCTTGAAAGACATTTGTTCTCCCAAAACAGATTACTAGAAATATTTAACTATGAACTG AAGGCAGCATGTATAGTTGCTT >OriGene 5' read for NM_182771 unedited
TGCAAAATTTGNTAATACGACTCACTATAGGGCGGCCGCGATTCAGCTACGGGTCAGAGC TAGTCCACTAGGTGCTAATCAAATGCTGTGTTACAACACTGTGAGGTTTTCCCAGTTATA AGTGTCACTATTAGGGTTTTTTTTAATTGCAAAGCCAAATAAGGCTGTCAATTGCATCAT CTTACCTTATTTCTTCAGATTAAGTACTGTTTATAGTGGGATTTTTGGTGGATGTGGTGG CATCAGCATAATCTATGTTTCAGGCGTCCTATAGAAGAGGATTATTCTTCAGGGGATGTG GAAGAAAAGGTAGCAGCAATTGCAGAGACAGATGAATCTGCAGAATCAGAAGGTGTAATT GATTCTCATAAACGTAGAGAAATCCTTTCACGAAGACCCTCTTATAGGAAAATACTGAAT GAACTGTCCTCTGATGTGCCTGGTGTTCCCAAGATTGAAGAAGAGAGATCAGAGGAAGAA GGAACACCACCTAGTATTGCTACCATGGCAGTACCAACTAGCATATATCAGACTAGCACG GGGCAATACATTGCTATAGCCCAAGGTGGAACAATCCAGATTTCTAACCCAGGATCTGAT GGTGTTCANGGACTGCAGGCATTAACAATGACAAATTCAGGAGCTCCTCCACCAGGTGCT ACAATTGTACAGTACGCAGCACAATCAGCTGATGGCACACAGCAGTTCTTTGTCCCANGC AGCCAGGTTGTTGTTCAAGCTGCCACTGGTGACATGCCAACTACCAGATCCCGAGCTCTA CTGCTGCTTTGCCACAGGAGTGGTGATGGCTGCATCGCCCGGAGTTTGCACAGTCCCCAG CAGCTGGCANAAGAAGCACACGCAAACGAGAGCTGAGGCTAATGAAAAACAAGGAAGCCT GCCAAGATGGTCAACGTC >OriGene 3' read for NM_182771 unedited
TACGAGCACTCGTGGAATGGGGTCACAGGGATCGCCATTCGGCATCGGGTCAGGAGAAGC AACTATACATGCTGCCTTCATTTCATAGTTAAATATTTCTAGTAATCTGTATTGGGAGAA CAAATGTCTTTCAAGGTTTCAAGTTCCTCTGTAAGCTTCTTGTTCTGGACTTCCATCACT GCAACTCGGCTCTCCAAACATTTTACATATTCTTTCTTTCGACGTCGACATTCTTTGGCA GCTTCCCTGTTTTTCATTAGCCTCAGCTCTCGTTTGCACTGTTGATTCTTCTGCCAGCTG CTGGGGACTGTGCAAACTTCCGGGCGATGCAGCCATCACCACTCCCTGTGGCAAAGCATC AGTACGAGCTCGGATCTGGTAAGTTGGCATGTCACCAGTGGCAGCTTGCACAACAACCTG GCTGCCTGGGACAAAGAACTGCTGTGTGCCATCAGCTGATTGTGCTGCGTACTGTACAAT TGTAGCACCTGGTGGACGAGCTCCTGAATTTGTCATTGTTAATGCCTGCAGTCCCTGAAC ACCATCACATCCTGGGTTAGAAATCTGGATTGTTCCACCTTGCGCTATATCAATGTATTG CCCCGTGCTAGTCTGATATATGCTAGTTAGCACTGCCATGGTAGCAATACTATGTGGCGT TCCCTCTTCCACTGATCTGTCTTCTTCAACTTGGGTACACGCTGCACATCACAGGACAGT TCACTCAGTATTGTCCTATAACATGGTCTTCGTGAAACGATTCCTCTACCTTTATGACAC TCAATTACACCTTCTGATTCTGCAGATTCATCTGTCTCTGCAATTGCCGCTACCTTTTGC TCCACATCCCCTGAAGAATAATCCTCTTCT |
Restriction Sites | Please inquire |
ACCN | NM_182771 |
Insert Size | 800 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This construct is a cloned PCR fragment that was fully sequenced. The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_182771.1, NP_877572.1 |
RefSeq Size | 2160 bp |
RefSeq ORF | 813 bp |
Locus ID | 1390 |
Cytogenetics | 10p11.21 |
Protein Families | Druggable Genome, Transcription Factors |
Gene Summary | 'This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]' Transcript Variant: This variant (15), also known as CREM theta1-tau2-beta, uses an alternative downstream promoter, and differs in the 5' UTR and 5' coding region, compared to variant 1. This results in a shorter isoform (15, also known as o) with a distinct N-terminus, compared to isoform 1. This isoform represents an activator isoform theta 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC215521 | CREM (Myc-DDK-tagged)-Human cAMP responsive element modulator (CREM), transcript variant 15 |
USD 420.00 |
|
RG215521 | CREM (GFP-tagged) - Human cAMP responsive element modulator (CREM), transcript variant 15 |
USD 460.00 |
|
RC215521L1 | Lenti ORF clone of Human cAMP responsive element modulator (CREM), transcript variant 15, Myc-DDK-tagged |
USD 620.00 |
|
RC215521L2 | Lenti ORF clone of Human cAMP responsive element modulator (CREM), transcript variant 15, mGFP tagged |
USD 620.00 |
|
RC215521L3 | Lenti ORF clone of Human cAMP responsive element modulator (CREM), transcript variant 15, Myc-DDK-tagged |
USD 620.00 |
|
RC215521L4 | Lenti ORF clone of Human cAMP responsive element modulator (CREM), transcript variant 15, mGFP tagged |
USD 620.00 |
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