GPCR 2037 (GPR151) (NM_194251) Human Untagged Clone

CAT#: SC307577

GPR151 (untagged)-Human G protein-coupled receptor 151 (GPR151)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GPR151
• Synonyms: GALR4; GALRL; GPCR; GPCR-2037; PGR7
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_194251 edited
  ATGCTGGCAGCTGCCTTTGCAGACTCTAACTCCAGCAGCATGAATGTGTCCTTTGCTCAC
  CTCCACTTTGCCGGAGGGTACCTGCCCTCTGATTCCCAGGACTGGAGAACCATCATCCCG
  GCTCTCTTGGTGGCTGTCTGCCTGGTGGGCTTCGTGGGAAACCTGTGTGTGATTGGCATC
  CTCCTTCACAATGCTTGGAAAGGAAAGCCATCCATGATCCACTCCCTGATTCTGAATCTC
  AGCCTGGCTGATCTCTCCCTCCTGCTGTTTTCTGCACCTATCCGAGCTACGGCGTACTCC
  AAAAGTGTTTGGGATCTAGGCTGGTTTGTCTGCAAGTCCTCTGACTGGTTTATCCACACA
  TGCATGGCAGCCAAGAGCCTGACAATCGTTGTGGTGGCCAAAGTATGCTTCATGTATGCA
  AGTGACCCAGCCAAGCAAGTGAGTATCCACAACTACACCATCTGGTCAGTGCTGGTGGCC
  ATCTGGACTGTGGCTAGCCTGTTACCCCTGCCGGAATGGTTCTTTAGCACCATCAGGCAT
  CATGAAGGTGTGGAAATGTGCCTCGTGGATGTACCAGCTGTGGCTGAAGAGTTTATGTCG
  ATGTTTGGTAAGCTCTACCCACTCCTGGCATTTGGCCTTCCATTATTTTTTGCCAGCTTT
  TATTTCTGGAGAGCTTATGACCAATGTAAAAAACGAGGAACTAAGACTCAAAATCTTAGA
  AACCAGATACGCTCAAAGCAAGTCACAGTGATGCTGCTGAGCATTGCCATCATCTCTGCT
  CTCTTGTGGCTCCCCGAATGGGTAGCTTGGCTGTGGGTATGGCATCTGAAGGCTGCAGGC
  CCGGCCCCACCACAAGGTTTCATAGCCCTGTCTCAAGTCTTGATGTTTTCCATCTCTTCA
  GCAAATCCTCTCATTTTTCTTGTGATGTCGGAAGAGTTCAGGGAAGGCTTGAAAGGTGTA
  TGGAAATGGATGATAACCAAAAAACCTCCAACTGTCTCAGAGTCTCAGGAAACACCAGCT
  GGCAACTCAGAGGGTCTTCCTGACAAGGTTCCATCTCCAGAATCCCCAGCATCCATACCA
  GAAAAAGAGAAACCCAGCTCTCCCTCCTCTGGCAAAGGGAAAACTGAGAAGGCAGAGATT
  CCCATCCTTCCTGACGTAGAGCAGTTTTGGCATGAGAGGGACACAGTCCCTTCTGTACAG
  GACAATGACCCTATCCCCTGGGAACATGAAGATCAAGAGACAGGGGAAGGTGTTAAATAG
  
• Restriction Sites: Please inquire
• ACCN: NM_194251
• ORF Size: 1260 bp
• Insert Size: 1300
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_194251.2, NP_919227.2
• RefSeq Size: 1260
• RefSeq ORF: 1260
• Locus ID: 134391
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the SOG subfamily that includes somatostatin, opioid, galanin, and kisspeptin receptors. The orthologous mouse gene has a restricted pattern of neuronal expression which is induced following nerve injury. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017]