Girdin (CCDC88A) (NM_018084) Human Untagged Clone

CAT#: SC308873

CCDC88A (untagged)-Human coiled-coil domain containing 88A (CCDC88A), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCDC88A
• Synonyms: APE; GIRDIN; GIV; GRDN; HkRP1; KIAA1212; PEHO; PEHOL
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_018084, the custom clone sequence may differ by one or more nucleotides
  ATGGAGAACGAAATTTTTACTCCCCTTCTGGAGCAGTTCATGACCAGCCCTTTGGTCACT
  TGGGTTAAAACGTTTGGACCTCTGGCCGCAGGAAATGGGACCAACCTTGATGAATATGTG
  GCTTTGGTGGATGGGGTATTCTTGAACCAGGTCATGCTCCAAATTAATCCTAAATTGGAG
  AGTCAGAGAGTAAATAAAAAAGTCAATAATGATGCCTCACTTAGAATGCACAATCTATCC
  ATTTTGGTGAGACAGATAAAATTTTATTACCAGGAGACTTTGCAGCAATTGATCATGATG
  TCGTTGCCAAATGTCTTAATCATTGGCAAAAATCCCTTTTCTGAACAAGGCACAGAAGAA
  GTTAAAAAACTGCTTTTACTTTTATTGGGTTGTGCAGTTCAGTGTCAGAAAAAAGAGGAA
  TTTATTGAAAGAATTCAAGGTTTAGATTTTGATACAAAAGCAGCGGTTGCCGCACATATT
  CAAGAGGTAACTCATAATCAGGAAAATGTGTTTGACCTGCAATGGATGGAAGTGACTGAT
  ATGTCGCAGGAGGACATAGAACCACTCTTGAAAAATATGGCATTGCATCTAAAAAGACTT
  ATAGATGAGAGAGATGAACATTCAGAGACTATCATAGAACTCTCTGAAGAGCGGGATGGT
  CTCCATTTTCTACCCCATGCCTCTTCATCTGCACAGTCACCCTGTGGTTCTCCAGGCATG
  AAGCGAACAGAAAGTCGACAACATCTGTCGGTGGAACTGGCAGATGCTAAAGCCAAGATA
  AGAAGGCTTAGGCAGGAATTGGAGGAAAAGACTGAGCAGTTGTTGGATTGTAAACAAGAA
  CTTGAGCAAATGGAAATAGAACTCAAAAGGCTGCAACAAGAGAACATGAATTTGCTTTCG
  GATGCTCGCTCTGCCAGAATGTACCGAGATGAATTAGATGCACTTCGAGAGAAAGCAGTC
  AGAGTCGATAAGCTTGAAAGTGAAGTCAGCAGATATAAAGAGAGACTACATGATATTGAA
  TTTTATAAGGCAAGAGTTGAGGAATTAAAAGAAGACAATCAAGTTTTATTAGAAACAAAA
  ACCATGTTGGAAGACCAACTAGAGGGAACTCGTGCTCGTTCTGATAAATTACATGAATTA
  GAAAAAGAGAACTTACAACTGAAAGCTAAACTTCATGATATGGAAATGGAACGAGATATG
  GATAGAAAAAAGATTGAAGAATTAATGGAAGAAAATATGACTTTGGAAATGGCACAGAAA
  CAAAGTATGGATGAATCATTACATCTTGGCTGGGAACTGGAACAGATATCCAGAACTAGT
  GAACTTTCCGAAGCACCCCAGAAATCCCTGGGCCATGAGGTGAATGAGTTGACATCAAGT
  AGATTATTGAAGCTAGAGATGGAAAATCAAAGTTTGACAAAAACCGTAGAAGAGCTTCGG
  ACTACTGTGGATTCTGTAGAAGGCAATGCTTCCAAAATCCTGAAAATGGAAAAAGAAAAT
  CAAAGGCTCAGTAAAAAGGTTGAGATTCTTGAAAATGAGATTGTTCAAGAAAAGCAAAGT
  CTTCAGAATTGTCAGAATTTAAGCAAGGATCTAATGAAGGAGAAAGCTCAGCTTGAAAAA
  ACAATAGAAACACTGAGAGAAAATTCAGAGAGACAGATTAAGATACTGGAACAGGAAAAT
  GAACATCTGAATCAAACAGTGTCTTCCTTAAGGCAGCGGTCCCAGATAAGTGCAGAAGCA
  AGAGTGAAAGACATTGAAAAAGAAAACAAAATTCTTCATGAATCTATCAAAGAAACAAGT
  AGCAAGCTAAGCAAGATTGAATTTGAAAAAAGACAAATTAAAAAAGAATTGGAACATTAT
  AAAGAAAAAGGAGAACGAGCTGAAGAACTTGAAAATGAATTGCATCATCTTGAAAAAGAA
  AATGAATTATTACAGAAAAAAATAACTAATTTAAAAATTACTTGTGAAAAAATTGAGGCC
  TTAGAACAAGAAAATTCAGAGCTAGAAAGAGAAAATAGAAAATTAAAAAAAACATTGGAT
  AGCTTTAAAAATCTGACCTTTCAGTTAGAATCCCTAGAAAAAGAGAATTCCCAACTTGAT
  GAGGAAAACTTAGAACTGCGAAGGAATGTAGAATCTTTGAAGTGTGCAAGCATGAAAATG
  GCTCAGCTACAGCTAGAAAACAAAGAACTGGAAAGTGAAAAAGAGCAACTTAAGAAGGGT
  TTGGAGCTCCTGAAAGCATCTTTCAAGAAAACAGAACGCTTAGAAGTTAGCTACCAGGGT
  TTAGATATAGAAAATCAAAGACTGCAAAAAACTTTAGAGAACAGCAATAAAAAAATCCAG
  CAATTAGAGAGTGAACTACAAGACTTAGAGATGGAAAATCAAACATTGCAGAAAAACCTA
  GAAGAACTAAAAATATCTAGCAAAAGACTAGAACAGCTGGAAAAAGAAAATAAATCATTA
  GAGCAAGAGACTTCTCAACTGGAAAAGGATAAGAAACAATTGGAGAAGGAAAATAAGAGA
  CTCCGACAACAAGCAGAAATTAAAGATACCACATTAGAAGAAAATAATGTGAAGATTGGA
  AATTTGGAAAAAGAAAACAAAACCCTATCCAAAGAAATTGGTATATATAAAGAATCTTGT
  GTCCGTCTGAAAGAACTAGAAAAAGAAAATAAGGAGCTTGTGAAAAGAGCAACTATTGAT
  ATAAAAACGTTGGTTACACTACGTGAGGATTTGGTGAGTGAAAAGTTGAAGACCCAACAG
  ATGAACAATGATCTCGAAAAATTAACTCATGAGCTTGAGAAGATAGGGTTAAATAAGGAG
  CGACTCTTACATGATGAACAAAGTACTGATGACAGTAGGTATAAACTTTTGGAATCAAAA
  TTAGAATCCACTCTTAAGAAGTCTCTTGAAATAAAAGAAGAAAAAATTGCTGCTTTAGAA
  GCTCGATTAGAAGAATCCACGAATTATAACCAGCAATTGCGCCAAGAACTTAAAACAGTG
  AAAAAAAATTATGAAGCTCTCAAACAGAGACAAGATGAGGAAAGGATGGTACAGAGCTCT
  CCTCCAATATCTGGTGAAGACAACAAATGGGAGCGAGAAAGTCAAGAAACGACTAGAGAA
  CTTCTGAAAGTTAAAGACAGATTAATTGAAGTAGAAAGAAATAATGCTACACTGCAAGCA
  GAGAAGCAAGCGTTGAAAACTCAACTGAAGCAACTTGAGACACAGAACAATAATTTGCAG
  GCTCAGATTCTTGCACTTCAGAGGCAGACAGTGTCATTACAAGAACAGAATACCACTCTT
  CAAACACAGAATGCCAAGCTTCAGGTTGAAAATTCCACCCTTAATTCCCAAAGTACCTCA
  CTCATGAACCAGAATGCCCAACTCCTAATCCAGCAGTCTTCCTTAGAAAATGAAAATGAA
  TCTGTAATCAAAGAGCGAGAAGACCTAAAATCTCTCTATGATTCTCTGATCAAAGATCAT
  GAAAAGCTGGAACTTCTTCATGAACGTCAGGCTTCAGAGTATGAATCTCTTATCTCTAAA
  CATGGAACTCTGAAGTCTGCCCACAAAAATCTTGAGGTGGAACATAGAGACCTTGAAGAC
  CGTTACAATCAGTTATTAAAACAGAAAGGACAGTTGGAAGATTTGGAAAAAATGCTCAAA
  GTAGAACAGGAAAAAATGCTGCTTGAAAATAAAAATCATGAAACAGTAGCTGCAGAATAC
  AAGAAACTTTGTGGTGAAAATGATAGGCTGAATCATACCTATAGTCAACTTTTAAAAGAG
  ACTGAAGTTTTACAAACTGACCATAAAAATTTGAAAAGTCTTCTGAATAATTCCAAACTG
  GAACAAACAAGATTAGAAGCTGAATTTTCAAAACTAAAGGAACAATACCAACAATTGGAT
  ATTACATCAACCAAGCTGAATAACCAGTGTGAGTTGCTAAGCCAACTTAAAGGAAATTTA
  GAAGAAGAAAATCGGCATCTACTAGATCAAATTCAGACATTAATGCTACAGAACAGAACA
  CTTTTGGAGCAGAATATGGAAAGCAAGGATCTTTTTCATGTTGAACAAAGACAGTACATT
  GATAAGTTAAATGAATTAAGACGTCAGAAGGAGAAACTAGAAGAGAAAATTATGGATCAA
  TACAAATTTTATGACCCATCTCCTCCTAGAAGGAGAGGCAACTGGATTACTCTAAAAATG
  AGAAAATTGATAAAGTCTAAGAAAGATATTAATCGGGAACGCCAGAAATCTCTAACATTA
  ACACCCACCCGCTCAGACTCCAGTGAAGGATTTCTTCAGCTCCCTCATCAAGACAGTCAA
  GATAGTTCTTCAGTAGGTTCAAACTCTTTAGAAGATGGCCAGACCTTGGGGACCAAGAAA
  AGCAGCACCATGAATGACCTGGTGCAGTCCATGGTCCTAGCAGGACAGTGGACAGGTAGT
  ACTGAGAATTTGGAGGTTCCTGATGATATTTCAACGGGTAAAAGGAGAAAAGAATTGGGA
  GCTATGGCCTTCTCTACTACAGCCATCAACTTTTCAACTGTCAACTCTTCTGCAGGCTTC
  AGATCCAAGCAGTTGGTTAATAATAAAGATACTACATCCTTTGAAGACATAAGTCCACAA
  GGTGTTAGTGATGATTCTAGTACGGGATCAAGAGTTCATGCTTCAAGACCAGCCAGCCTT
  GATAGTGGCAGAACATCCACTAGCAATAGCAATAATAATGCTTCACTACATGAAGTCAAA
  GCAGGTGCAGTTAATAACCAAAGCAGGCCACAAAGCCACAGCAGTGGAGAATTTAGCCTG
  CTTCATGACCATGAGGCTTGGTCCAGCAGTGGTAGCAGTCCAATCCAGTACTTGAAAAGA
  CAGACCAGATCAAGCCCAGTGCTCCAGCACAAAATATCTGAAACACTGGAGAGTCGACAT
  CACAAGATCAAAACTGGTTCCCCTGGAAGTGAAGTTGTTACTCTACAACAGTTTTTGGAA
  GAAAGCAATAAGCTTACCTCAGTACAGATAAAGTCCTCAAGTCAAGAGAATCTTTTAGAT
  GAAGTAATGAAAAGTTTGTCTGTCTCTTCTGACTTTTTGGGAAAAGACAAACCAGTTAGC
  TGTGGTCTGGCCAGGTCAGTAAGTGGAAAAACCCCAGGGGACTTCTATGATAGACGGACA
  ACTAAGCCTGAGTTTTTGAGACCTGGTCCTCGAAAAACTGAAGATACCTACTTCATTAGT
  TCTGCGGGAAAACCTACACCAGGCACTCAAGGAAAAATAAAATTAGTAAAAGAATCTTCT
  CTGTCACGACAATCAAAAGATAGTAACCCTTATGCAACTTTACCTCGTGCAAGCAGCGTG
  ATCTCAACTGCCGAAGGAACTACACGAAGGACAAGCATCCATGATTTTTTGACCAAGGAC
  AGTAGACTGCCTATATCAGTTGATTCACCACCAGCTGCTGCTGACAGCAACACCACTGCA
  GCATCTAATGTGGACAAAGTACAAGAAAGCAGAAATTCAAAAAGCAGGTCTAGGGAGCAA
  CAAAGCTCCTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_018084
• ORF Size: 5532 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_018084.3, NP_060554.3
• RefSeq Size: 9630
• RefSeq ORF: 5532
• Locus ID: 55704
• Gene Summary: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (2) uses an alternate splice site and lacks an exon in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.