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Pericentrin (PCNT) (NM_006031) Human Untagged Clone
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Other products for "PCNT"
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Symbol | PCNT |
| Synonyms | KEN; MOPD2; PCN; PCNT2; PCNTB; PCTN2; SCKL4 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_006031, the custom clone sequence may differ by one or more nucleotides
ATGGAAGTTGAGCAAGAGCAGCGGCGCAGAAAGGTGGAGGCCGGGAGGACGAAGCTTGCT CACTTCCGACAGAGAAAAACAAAAGGTGACAGTTCGCATTCGGAGAAAAAGACGGCGAAG AGGAAGGGCTCGGCTGTCGATGCGTCTGTCCAGGAGGAGAGTCCGGTAACCAAGGAGGAC AGCGCACTCTGTGGAGGAGGGGACATTTGCAAAAGCACATCATGTGACGACACCCCTGAT GGGGCAGGAGGGGCCTTTGCAGCTCAGCCGGAGGACTGTGATGGAGAGAAGAGAGAGGAC TTGGAACAGCTGCAGCAGAAGCAAGTCAATGACCATCCTCCAGAGCAGTGTGGGATGTTC ACAGTCAGTGACCACCCACCAGAACAGCATGGGATGTTCACAGTCGGTGACCACCCACCA GAACAGCGTGGGATGTTCACAGTCAGTGACCACCCACCAGAACAGCATGGGATGTTCACA GTCAGTGACCACCCACCAGAACAGCGTGGGATGTTCACAATCAGTGACCACCAACCGGAA CAGCGTGGGATGTTCACAGTCAGTGACCACACACCAGAACAGCGTGGGATCTTCACAATC AGTGACCACCCAGCAGAACAGCGTGGGATGTTCACAAAGGAGTGTGAACAAGAATGTGAA CTTGCCATTACTGACCTGGAGAGCGGCCGTGAAGATGAGGCTGGCCTGCATCAGAGTCAG GCCGTGCATGGCCTTGAGCTGGAGGCGCTGCGCCTGAGTCTGAGCAACATGCACACGGCG CAGCTGGAGCTGACACAGGCCAACCTCCAGAAGGAGAAGGAGACGGCATTGACGGAGCTG CGGGAGATGCTCAACAGCCGGCGTGCCCAGGAGCTGGCCCTGCTACAGAGCAGGCAGCAG CACGAGCTGGAGCTCCTCAGGGAGCAGCACGCACGGGAGAAGGAGGAGGTGGTGCTCAGG TGTGGACAGGAAGCAGCTGAGCTGAAGGAGAAGTTACAATCAGAAATGGAGAAAAACGCC CAGATAGTAAAGACCCTGAAGGAAGATTGGGAATCTGAAAAAGATTTATGTTTAGAAAAT CTACGCAAAGAACTGTCTGCAAAGCATCAATCAGAAATGGAGGATTTACAAAACCAGTTT CAGAAAGAATTGGCAGAACAGAGAGCTGAGTTGGAGAAGATTTTTCAAGACAAAAACCAG GCTGAACGGGCCCTTAGGAACCTGGAGAGTCATCATCAAGCAGCCATTGAGAAGTTACGT GAAGACCTGCAGTCCGAGCACGGCCGGTGTTTAGAAGACTTGGAGTTCAAGTTCAAAGAG AGCGAGAAAGAAAAACAGCTGGAGTTAGAGAATCTTCAAGCATCATATGAAGACCTGAAG GCACAATCACAAGAAGAGATCAGGCGCTTGTGGTCCCAGCTTGATTCTGCCAGGACCAGT AGACAGGAATTGAGTGAGCTACATGAGCAACTCCTGGCGCGCACCTCTCGTGTGGAAGAT TTAGAACAGCTGAAGCAGCGAGAAAAAACCCAGCATGAGTCCGAACTGGAGCAACTGAGG ATTTATTTTGAAAAGAAGTTAAGGGATGCTGAGAAAACTTACCAAGAAGACCTAACCCTG TTACAGCAGAGGCTGCAGGGGGCGAGGGAAGATGCTCTTCTGGACTCTGTGGAAGTTGGG TTGTCCTGTGTGGGTTTAGAAGAGAAACCTGAGAAAGGAAGAAAAGATCACGTTGATGAA CTCGAGCCTGAGCGACATAAGGAGAGCCTGCCACGCTTCCAGGCGGAGTTAGAAGAAAGC CACAGGCACCAGCTGGAAGCGCTGGAGTCTCCCCTCTGCATCCAGCACGAGGGGCATGTC TCAGACAGATGCTGCGTAGAGACTTCAGCATTGGGACACGAGTGGCGTCTGGAACCCTCT GAAGGGCACAGCCAAGAGCTTCCCTGGGTGCATCTCCAGGGTGTGCAGGACGGGGACTTG GAGGCCGACACAGAGCGGGCAGCCAGAGTCTTGGGTCTGGAAACTGAGCACAAGGTGCAA CTTTCGCTTCTTCAGACTGAGCTCAAAGAAGAAATTGAACTCCTAAAAATAGAAAATAGA AATTTGTATGGGAAGTTGCAGCATGAAACTCGTCTGAAGGACGATTTGGAGAAGGTAAAA CACAATCTAATTGAAGACCACCAGAAGGAACTAAATAATGCTAAGCAAAAGACTGAGCTG ATGAAACAGGAATTCCAAAGAAAAGAAACGGACTGGAAAGTTATGAAGGAGGAGCTACAG CGGGAAGCTGAGGAGAAGTTAACATTGATGCTACTTGAACTGAGAGAAAAGGCTGAATCC GAGAAACAGACCATCATAAACAAGTTTGAGCTTCGAGAAGCTGAAATGAGGCAGCTTCAG GACCAACAGGCAGCCCAGATCCTGGATCTGGAGAGGTCCTTGACGGAGCAGCAGGGCCGC CTGCAGCAGCTGGAACAGGACCTCACTTCAGACGACGCCCTGCATTGCAGCCAGTGTGGG CGGGAGCCGCCCACAGCCCAGGACGGGGAGCTTGCTGCGCTCCACGTGAAGGAAGACTGC GCCCTGCAGCTGATGCTGGCCCGGAGCAGGTTTTTAGAGGAACGTAAAGAGATCACCGAG AAATTCAGTGCGGAACAAGATGCCTTCCTGCAGGAGGCCCAGGAGCAGCATGCCCGTGAG CTGCAGCTCCTCCAGGAGAGACACCAGCAGCAGCTCCTGTCAGTGACGGCGGAGCTCGAG GCCAGACACCAGGCCGCGTTGGGCGAGCTGACAGCCTCCTTAGAGAGCAAGCAGGGGGCT CTGCTGGCTGCACGTGTGGCCGAACTGCAGACAAAACACGCTGCCGACCTCGGCGCTCTG GAGACCAGACATCTGTCCAGCCTTGATTCTTTGGAATCCTGTTACCTCTCTGAATTTCAG ACCATCCGTGAGGAGCACAGGCAGGCCCTAGAGCTCTTACGAGCAGACTTTGAGGAACAA CTGTGGAAAAAGGACTCTCTTCACCAAACGATTTTGACTCAAGAGTTGGAGAAACTGAAG CGGAAACACGAAGGGGAGCTACAGTCTGTGCGGGACCACCTGCGAACCGAAGTGAGCACA GAGCTCGCCGGAACCGTGGCTCACGAGCTGCAGGGAGTGCACCAGGGTGAATTTGGAAGT GAAAAGAAAACTGCTTTGCATGAAAAAGAGGAGACACTTCGGCTTCAGAGTGCACAGGCA CAGCCTTTTCACCAAGAGGAGAAAGAGTCTTTGTCTCTGCAGCTTCAAAAGAAGAATCAC CAAGTCCAGCAGCTGAAAGACCAGGTTTTATCCTTAAGTCACGAGATAGAAGAGTGCCGC TCCGAGTTGGAGGTGCTGCAGCAGAGGCGGGAGCGGGAGAACCGGGAAGGCGCAAACCTC CTCTCCATGCTCAAGGCCGACGTCAACCTGTCCCACAGCGAAAGAGGGGCCCTCCAGGAC GCCCTGCGCAGGCTGCTGGGTTTGTTTGGAGAGACGCTGAGGGCAGCCGTCACCCTGAGG AGCCGGATCGGGGAGCGCGTGGGGCTCTGCCTGGATGACGCGGGCGCAGGCCTGGCCCTG TCGACAGCTCCGGCGCTGGAGGAGACATGGTCTGATGTGGCCCTCCCGGAGTTGGACAGA ACTTTGTCTGAATGTGCAGAGATGTCTTCCGTGGCTGAAATTAGCAGCCACATGCGTGAA AGCTTTCTCATGAGCCCAGAAAGTGTGCGGGAGTGTGAGCAGCCCATCCGGAGGGTCTTC CAGAGCCTCAGCCTGGCCGTGGACGGCCTCATGGAGATGGCCCTGGACTCCAGCAGGCAG CTGGAAGAAGCACGCCAAATTCATTCTCGTTTTGAAAAAGAATTTAGTTTTAAGAATGAG GAGACAGCACAGGTTGTCAGGAAGCACCAGGAGCTGCTGGAGTGTTTGAAGGAGGAGAGC GCAGCAAAGGCAGAGCTGGCGCTGGAGCTGCACAAGACTCAGGGTACCCTTGAGGGATTC AAGGTGGAGACAGCAGATCTGAAGGAGGTGCTGGCCGGGAAGGAGGATTCCGAGCACCGT CTGGTGCTGGAGCTGGAGAGCCTGAGACGGCAGCTGCAGCAGGCGGCCCAGGAGCAGGCG GCGCTGAGGGAGGAGTGCACCCGTCTGTGGAGTCGGGGGGAGGCCACAGCCACGGACGCC GAGGCCAGAGAAGCTGCTCTCCGGAAGGAAGTGGAGGATCTGACCAAAGAACAGTCGGAG ACCAGGAAGCAGGCTGAGAAGGACCGCTCAGCCCTGCTCTCCCAGATGAAGATTTTGGAG TCTGAGTTAGAAGAACAGCTGTCTCAGCATCGCGGGTGTGCCAAGCAGGCGGAGGCCGTC ACTGCCCTGGAACAGCAGGTGGCATCTCTGGACAAGCATTTGCGCAACCAGCGGCAATTC ATGGATGAGCAGGCAGCCGAGCGGGAGCACGAGCGCGAGGAGTTCCAGCAGGAGATTCAG AGGCTGGAGGGGCAGCTCCGCCAGGCGGCCAAGCCGCAGCCCTGGGGCCCTCGCGACAGC CAGCAGGCGCCGCTGGATGGAGAGGTTGAGTTGTTACAACAAAAGTTGAGAGAAAAGTTG GATGAATTTAATGAATTGGCTATACAGAAAGAGTCGGCAGATAGACAAGTGTTAATGCAG GAAGAAGAAATTAAACGTCTGGAGGAGATGAACATCAACATCAGGAAAAAAGTGGCCCAG CTCCAGGAAGAAGTGGAAAAACAGAAAAACATCGTGAAAGGGCTGGAACAGGATAAAGAG GTGTTAAAGAAACAGCAGATGAGTAGCTTGCTTCTGGCGTCCACGTTGCAGTCTACACTA GATGCAGGCAGATGTCCCGAGCCTCCTTCGGGCAGCCCTCCTGAGGGTCCAGAAATACAG TTAGAGGTGACACAGAGAGCACTCCTGCGGCGCGAGAGCGAGGTTTTGGACTTAAAAGAA CAGCTAGAAAAGATGAAAGGTGACTTAGAAAGTAAAAATGAAGAAATACTACATCTGAAC TTAAAATTGGACATGCAGAACAGCCAGACTGCTGTCAGCCTCAGAGAACTTGAGGAAGAG AACACGAGCTTGAAGGTCATATATACCAGAAGTTCTGAGATTGAAGAGCTGAAAGCCACT ATTGAAAATCTGCAAGAGAATCAGAAACGATTACAAAAGGAGAAAGCAGAGGAAATTGAA CAACTCCATGAAGTCATTGAGAAGCTGCAGCACGAGCTGTCCCTCATGGGGCCTGTGGTG CACGAAGTCAGCGACAGTCAGGCTGGCAGTCTGCAGAGCGAGCTGCTCTGCTCCCAGGCC GGGGGCCCTCGTGGGCAGGCCCTACAGGGCGAGCTCGAGGCTGCGCTGGAAGCCAAGGAG GCCCTGAGCCGGCTGCTGGCTGACCAGGAGCGCAGGCACAGCCAGGCCCTGGAGGCCCTG CAGCAGCGCCTCCAGGGCGCAGAGGAGGCTGCGGAGCTACAGCTGGCTGAGCTGGAGCGC AATGTAGCCCTCAGGGAGGCTGAGGTCGAAGACATGGCCTCCCGGATCCAGGAGTTCGAA GCGGCCCTGAAAGCAAAGGAAGCGACGATTGCCGAGAGAAATTTAGAAATCGACGCTCTG AACCAGCGGAAGGCGGCCCACTCTGCCGAGCTGGAGGCCGTCCTGTTGGCCTTGGCCCGC ATCCGCCGCGCCCTGGAGCAGCAGCCCCTGGCAGCCGGGGCGGCGCCTCCCGAGCTGCAG TGGCTCCGAGCGCAGTGTGCCCGCCTCAGCCGCCAGCTGCAGGTGCTGCACCAGCGGTTC CTGAGGTGCCAGGTGGAGCTGGACAGGCGGCAGGCCCGCAGAGCCACAGCTCACACACGG GTGCCCGGGGCCCACCCACAGCCTCGCATGGATGGTGGCGCCAAGGCCCAGGTCACCGGC GACGTGGAGGCCTCCCATGATGCTGCTTTGGAGCCGGTTGTCCCTGACCCACAGGGTGAT CTGCAGCCTGTCCTGGTGACGTTGAAGGATGCACCTCTCTGCAAGCAAGAAGGCGTGATG TCAGTGCTCACCGTCTGCCAGAGGCAGCTGCAGTCGGAGCTGCTCTTGGTGAAAAATGAA ATGCGCCTGAGTCTGGAGGACGGCGGCAAGGGTAAAGAAAAAGTACTGGAAGATTGTCAG CTGCCGAAGGTCGATCTCGTAGCTCAGGTGAAACAGCTTCAGGAAAAACTGAACCGTTTG CTGTATTCCATGACCTTCCAGAATGTGGATGCTGCCGACACCAAATCTCTGTGGCCCATG GCCTCAGCACACCTGTTGGAGAGCAGCTGGAGTGATGATTCCTGTGACGGAGAAGAGCCT GACATATCACCCCACATAGACACATGTGATGCCAATACAGCCACGGGGGGTGTAACTGAT GTTATCAAAAATCAGGCCATAGACGCGTGTGATGCCAATACAACCCCAGGGGGTGTAACT GATGTTATCAAAAATTGGGATTCCTTGATACCAGATGAAATGCCAGATTCTCCCATTCAA GAAAAATCAGAATGTCAGGACATGTCTCTTTCTTCACCGACCAGCGTACTTGGTGGCTCC CGCCACCAGAGCCACACTGCAGAGGCTGGGCCCCGGAAGAGCCCGGTCGGGATGCTGGAC CTGTCTTCCTGGAGCTCCCCTGAGGTCCTCAGGAAGGACTGGACCCTGGAGCCCTGGCCC AGCCTCCCCGTGACACCCCACTCAGGAGCCCTGAGCCTGTGCAGTGCCGACACATCCCTG GGGGACAGGGCGGACACCTCGCTGCCACAGACCCAGGGGCCGGGGCTGCTTTGTTCCCCA GGCGTGTCTGCAGCAGCGCTGGCACTGCAGTGGGCCGAGTCTCCGCCGGCTGACGACCAC CATGTGCAGAGGACGGCTGTGGAGAAAGATGTCGAAGATTTTATCACAACATCCTTTGAT TCTCAAGAAACATTAAGTTCACCTCCTCCTGGATTAGAAGGAAAAGCTGATAGAAGTGAG AAAAGTGACGGCTCGGGTTTTGGAGCAAGACTGAGCCCGGGGTCAGGAGGCCCTGAGGCT CAAACTGCTGGTCCTGTGACCCCTGCTTCCATCTCTGGAAGGTTTCAGCCGCTGCCGGAA GCCATGAAGGAGAAGGAAGTGCGTCCGAAGCACGTGAAGGCTTTACTGCAGATGGTGCGT GACGAGAGCCACCAGATCCTGGCGCTGTCAGAAGGCCTTGCACCCCCAAGCGGCGAGCCA CACCCACCCCGGAAGGAAGACGAGATACAGGACATCTCGCTCCATGGGGGAAAGACGCAG GAAGTGCCCACCGCGTGCCCCGATTGGAGAGGGGACCTTCTGCAGGTTGTGCAAGAGGCC TTTGAAAAAGAGCAGGAGATGCAGGGGGTTGAGCTGCAGCCCCGACTCAGTGGCTCAGAT CTGGGGGGTCACAGCTCCCTGCTCGAAAGGCTGGAGAAGATCATCCGTGAGCAGGGAGAC CTGCAGGAAAAGTCCCTGGAGCATCTTCGCTTGCCGGACCGGAGCAGCCTGCTGTCCGAG ATCCAGGCGCTGCGTGCCCAGCTGCGCATGACGCACCTGCAGAACCAGGAGAAGCTGCAG CACTTGCGCACGGCGCTGACAAGCGCAGAGGCGCGCGGGAGCCAGCAGGAGCACCAGCTG CGCAGGCAGGTTGAACTGCTGGCTTATAAAGTAGAGCAGGAGAAGTGCATTGCTGGTGAC TTGCAGAAGACGCTGAGTGAAGAGCAAGAGAAGGCAAACAGCGTGCAGAAGCTCCTGGCG GCGGAGCAGACTGTAGTGCGAGATTTGAAGTCCGACCTCTGTGAGAGCAGGCAGAAGAGC GAACAGCTGTCCCGGTCCCTCTGCGAGGTGCAGCAGGAGGTCCTCCAGCTGAGATCCATG CTGAGCAGTAAGGAGAACGAGCTGAAGGCCGCGCTTCAGGAGCTGGAGAGTGAGCAGGGG AAGGGGCGTGCCCTGCAGAGCCAGCTGGAGGAGGAGCAGCTGCGGCACCTGCAGAGGGAG AGCCAGAGTGCCAAGGCCCTGGAGGAGCTGCGGGCGTCTTTGGAGACACAGCGTGCTCAG AGCAGTCGACTCTGCGTGGCACTGAAACACGAGCAGACGGCCAAGGACAACCTGCAGAAG GAGCTGCGTATCGAGCACTCACGCTGCGAGGCCTTGCTGGCTCAGGAGCGGAGCCAGCTC TCTGAGCTCCAGAAGGACCTTGCGGCTGAGAAGAGCCGCACCCTGGAGCTGTCAGAGGCC TTGCGGCACGAGCGGCTCCTGACCGAGCAGCTGAGCCAGAGGACACAGGAGGCTTGCGTG CACCAGGACACACAGGCCCATCACGCTCTGCTGCAGAAGCTGAAGGAGGAGAAGTCCCGG GTGGTGGACTTGCAAGCGATGCTTGAAAAGGTGCAGCAGCAAGCCCTGCATTCTCAGCAG CAGCTTGAGGCTGAGGCTCAGAAGCACTGTGAGGCGCTCAGGAGAGAGAAGGAGGTAAGT GCCACACTGAAGTCGACGGTGGAAGCCCTGCACACCCAAAAACGAGAGCTGAGATGCTCT CTGGAGAGAGAGAGGGAGAAACCAGCGTGGTTGCAGGCAGAATTAGAGCAGTCACACCCA CGGTTGAAAGAGCAAGAAGGACGCAAGGCTGCGAGGAGGAGCGCGGAGGCCAGGCAGAGC CCAGCGGCTGCGGAGCAGTGGAGGAAGTGGCAGAGAGACAAGGAGAAGCTGCGAGAATTA GAACTGCAGCGTCAGCGTGACTTGCATAAGATCAAGCAGCTTCAGCAGACAGTGAGAGAC CTGGAGTCGAAGGACGAGGTGCCTGGCAGCCGCCTCCACCTAGGTTCTGCCCGCAGGGCT GCCGGCTCGGATGCGGACCACCTCCGGGAACAGCAGCGAGAGCTGGAGGCGATGAGGCAG CGGCTGCTCTCTGCCGCCCGGCTTCTCACCAGCTTCACCAGCCAGGCCGTGGACAGGACA GTTAATGATTGGACGTCATCCAATGAGAAAGCAGTGATGTCTTTACTGCACACGTTGGAG GAGCTGAAGTCTGACTTGAGCAGGCCCACCTCCTCCCAGAAAAAAATGGCAGCAGAGCTG CAGTTCCAGTTTGTGGACGTCCTGCTGAAAGACAATGTTTCCCTCACAAAAGCGCTCAGC ACGGTGACCCAGGAGAAGCTGGAGCTGAGCAGAGCCGTGTCTAAGCTTGAGAAGTTGCTG AAGCACCATCTGCAGAAGGGCTGCAGCCCAAGCAGGTCGGAAAGGTCTGCTTGGAAGCCA GACGAAACGGCTCCACAGAGTTCCCTGAGGCGCCCAGACCCCGGCCGGCTTCCACCAGCT GCCAGCGAGGAAGCACACACCAGCAATGTCAAGATGGAAAAATTGTACCTGCATTACTTG AGAGCAGAGAGCTTTAGAAAAGCTCTGATTTATCAAAAGAAGTATCTTTTGCTGTTGATT GGTGGATTCCAGGATTCTGAACAAGAAACACTCTCCATGATTGCCCATTTGGGGGTATTT CCTTCCAAAGCAGAACGGAAAATCACATCTCGTCCTTTCACCAGGTTCCGCACGGCCGTC AGGGTGGTCATTGCAATATTAAGATTACGTTTTTTGGTTAAGAAATGGCAAGAAGTAGAT CGGAAAGGAGCTCTGGCACAAGGCAAAGCCCCTCGCCCAGGGCCCCGAGCACGACAGCCG CAGTCTCCACCCAGAACCAGAGAGTCCCCCCCAACCCGGGATGTACCCTCTGGCCACACC AGGGACCCTGCCAGAGGCCGCAGACTGGCAGCAGCAGCCTCCCCACACAGTGGGGGAAGA GCCACTCCATCCCCAAATTCAAGATTAGAAAGATCCCTGACTGCTTCTCAAGATCCAGAA CATTCCTTGACAGAGTATATTCACCATTTAGAAGTGATCCAGCAAAGATTGGGAGGGGTA CTACCAGATTCTACTTCAAAGAAATCCTGCCACCCGATGATTAAACAGTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_006031 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006031.4, NP_006022.3 |
| RefSeq Size | 10554 bp |
| RefSeq ORF | 10011 bp |
| Locus ID | 5116 |
| Cytogenetics | 21q22.3 |
| Domains | M |
| Gene Summary | 'The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]' Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
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