PI 3 Kinase Class 2A (PIK3C2A) (NM_002645) Human Untagged Clone

CAT#: SC309022

PIK3C2A (untagged)-Human phosphoinositide-3-kinase, class 2, alpha polypeptide (PIK3C2A)


  "NM_002645" in other vectors (4)

Reconstitution Protocol

USD 2,820.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PIK3C2A
Synonyms CPK; OCSKD; PI3-K-C2(ALPHA); PI3-K-C2A; PI3K-C2-alpha; PI3K-C2alpha
Vector pCMV6-XL6
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_002645 edited
GGCCTTGCTATTTTGGAAGCTACAAGAAAAAAATAGAGGAAGGAAGGTTTGGTCTTTTTA
GTGGACATGGCTCAGATATCTAGCAACAGCGGATTTAAAGAATGTCCATCTTCACATCCG
GAACCAACAAGAGCAAAAGATGTGGACAAAGAAGAAGCATTACAGATGGAAGCAGAGGCT
TTAGCAAAACTGCAAAAGGATAGACAAGTGACTGACAATCAGAGAGGCTTTGAGTTGTCA
AGCAGCACCAGAAAAAAAGCACAGGTTTATAACAAGCAGGATTATGATCTCATGGTGTTT
CCTGAATCAGATTCCCAAAAAAGAGCATTAGATATTGATGTAGAAAAGCTCACCCAAGCT
GAACTTGAGAAACTATTGCTGGATGACAGTTTCGAGACTAAAAAAACACCTGTATTACCA
GTTACTCCTATTCTGAGCCCTTCCTTTTCAGCACAGCTCTATTTTAGACCTACTATTCAG
AGAGGACAGTGGCCACCTGGATTACCTGGGCCTTCCACTTATGCTTTACCTTCTATTTAT
CCTTCTACTTACAGTAAACAGGCTGCATTCCAAAATGGCTTCAATCCAAGAATGCCCACT
TTTCCATCTACAGAACCTATATATTTAAGTCTTCCGGGACAATCTCCATATTTCTCATAT
CCTTTGACACCTGCCACACCCTTTCATCCACAAGGAAGCTTACCTATCTATCGTCCAGTA
GTCAGTACTGACATGGCAAAACTATTTGACAAAATAGCTAGTACATCAGAATTTTTAAAA
AATGGGAAAGCAAGGACTGATTTGGAGATAACAGATTCAAAAGTCAGCAATCTACAGGTA
TCTCCAAAGTCTGAGGATATCAGTAAATTTGACTGGTTAGACTTGGATCCTCTAAGTAAG
CCTAAGGTGGATAATGTGGAGGTATTAGACCATGAGGAAGAGAAAAATGTTTCAAGTTTG
CTAGCAAAGGATCCTTGGGATGCTGTTCTTCTTGAAGAGAGATCGACAGCAAATTGTCAT
CTTGAAAGAAAGGTGAATGGAAAATCCCTTTCTGTGGCAACTGTTACAAGAAGCCAGTCT
TTAAATATTCGAACAACTCAGCTTGCAAAAGCCCAGGGCCATATATCTCAGAAAGACCCA
AATGGGACCAGTAGTTTGCCAACTGGAAGTTCTCTTCTTCAAGAAGTTGAAGTACAGAAT
GAGGAGATGGCAGCTTTTTGTCGATCCATTACAAAATTGAAGACCAAATTTCCATATACC
AATCACCGCACAAACCCAGGCTATTTGTTAAGTCCAGTCACAGCGCAAAGAAACATATGC
GGAGAAAATGCTAGTGTGAAGGTCTCCATTGACATTGAAGGATTTCAGCTACCAGTTACT
TTTACGTGTGATGTGAGTTCTACTGTAGAAATCATTATAATGCAAGCCCTTTGCTGGGTA
CATGATGACTTGAATCAAGTAGATGTTGGCAGCTATGTTCTAAAAGTTTGTGGTCAAGAG
GAAGTGCTGCAGAATAATCATTGCCTTGGAAGTCATGAGCATATTCAAAACTGTCGAAAA
TGGGACACAGAAATTAGACTACAACTCTTGACCTTCAGTGCAATGTGTCAAAATCTGGCC
CGAACAGCAGAAGATGATGAAACACCCGTGGATTTAAACAAACACCTGTATCAAATAGAA
AAACCTTGCAAAGAAGCCATGACGAGACACCCTGTTGAAGAACTCTTAGATTCTTATCAC
AACCAAGTAGAACTGGCTCTTCAAATTGAAAACCAACACCGAGCAGTAGATCAAGTAATT
AAAGCTGTAAGAAAAATCTGTAGTGCTTTAGATGGTGTCGAGACTCTTGCCATTACAGAA
TCAGTAAAGAAGCTAAAGAGAGCAGTTAATCTTCCAAGGAGTAAAACTGCTGATGTGACT
TCTTTGTTTGGAGGAGAAGACACTAGCAGGAGTTCAACTAGGGGCTCACTTAATCCTGAA
AATCCTGTTCAAGTAAGCATAAACCAATTAACTGCAGCAATTTATGATCTTCTCAGACTC
CATGCAAATTCTGGTAGGAGTCCTACAGACTGTGCCCAAAGTAGCAAGAGTGTCAAGGAA
GCATGGACTACAACAGAGCAGCTCCAGTTTACTATTTTTGCTGCTCATGGAATTTCAAGT
AATTGGGTATCAAATTATGAAAAATACTACTTGATATGTTCACTGTCTCACAATGGAAAG
GATCTTTTTAAACCTATTCAATCAAAGAAGGTTGGCACTTACAAGAATTTCTTCTATCTT
ATTAAATGGGATGAACTAATCATTTTTCCTATCCAGATATCACAATTGCCATTAGAATCA
GTTCTTCACCTTACTCTTTTTGGAATTTTAAATCAGAGCAGTGGAAGTTCCCCTGATTCT
AATAAGCAGAGAAAGGGACCAGAAGCTTTGGGCAAAGTTTCTTTACCTCTTTTTGACTTT
AAACGGTTTTTAACATGTGGAACTAAACTTCTATATCTTTGGACTTCATCACATACAAAT
TCTGTTCCTGGAACAGTTACCAAAAAAGGATATGTCATGGAAAGAATAGTGCTACAGGTT
GATTTTCCTTCTCCTGCATTTGATATTATTTATACAACTCCTCAAGTTGACAGAAGCATT
ATACAGCAACATAACTTAGAAACACTAGAGAATGATATAAAAGGGAAACTTCTTGATATT
CTTCATAAAGACTCATCACTTGGACTTTCTAAAGAAGATAAAGCTTTTTTATGGGAGAAA
CGTTATTATTGCTTCAAACACCCAAATTGTCTTCCTAAAATATTAGCAAGCGCCCCAAAC
TGGAAATGGGTTAATCTTGCCAAAACTTACTCATTGCTTCACCAGTGGCCTGCATTGTAC
CCACTAATTGCATTGGAACTTCTTGATTCAAAATTTGCTGATCAGGAAGTAAGATCCCTA
GCTGTGACCTGGATTGAGGCCATTAGTGATGATGAGCTAACAGATCTTCTTCCACAGTTT
GTACAAGCTTTGAAATATGAAATTTACTTGAATAGTTCATTAGTGCAATTCCTTTTGTCC
AGGGCATTGGGAAATATCCAGATAGCACACAATTTATATTGGCTTCTCAAAGATGCCCTG
CATGATGTACAGTTTAGTACCCGATACGAACATGTTTTGGGTGCTCTCCTGTCAGTAGGA
GGAAAACGACTTAGAGAAGAACTTCTAAAACAGACGAAACTTGTACAGCTTTTAGGAGGA
GTAGCAGAAAAAGTAAGGCAGGCTAGTGGATCAGCCAGACAGGTTGTTCTCCAAAGAAGT
ATGGAACGAGTACAGTCCTTTTTTCAGAAAAATAAATGCCGTCTCCCTCTCAAGCCAAGT
CTAGTGGCAAAAGAATTAAATATTAAGTCGTGTTCCTTCTTCAGTTCTAATGCTGTCCCC
CTAAAAGTCACAATGGTGAATGCTGACCCTATGGGAGAAGAAATTAATGTCATGTTTAAG
GTTGGTGAAGATCTTCGGCAAGATATGTTAGCTTTACAGATGATAAAGATTATGGATAAG
ATCTGGCTTAAAGAAGGACTAGATCTGAGGATGGTAATTTTCAAATGTCTCTCAACTGGC
AGAGATCGAGGCATGGTGGAGCTGGTTCCTGCTTCCGATACCCTCAGGAAAATCCAAGTG
GAATATGGTGTGACAGGATCCTTTAAAGATAAACCACTTGCAGAGTGGCTAAGGAAATAC
AATCCCTCTGAAGAAGAATATGAAAAGGCTTCAGAGAACTTTATCTATTCCTGTGCTGGA
TGCTGTGTAGCCACCTATGTTTTAGGCATCTGTGATCGACACAATGACAATATAATGCTT
CGAAGCACGGGACACATGTTTCACATTGACTTTGGAAAGTTTTTGGGACATGCACAGATG
TTTGGCAGCTTCAAAAGGGATCGGGCTCCTTTTGTGCTGACCTCTGATATGGCATATGTC
ATTAATGGGGGTGAAAAGCCCACCATTCGTTTTCAGTTGTTTGTGGACCTCTGCTGTCAG
GCCTACAACTTGATAAGAAAGCAGACAAACCTTTTTCTTAACCTCCTTTCACTGATGATT
CCTTCAGGGTTACCAGAACTTACAAGTATTCAAGATTTGAAATACGTTAGAGATGCACTT
CAACCCCAAACTACAGACGCAGAAGCTACAATTTTCTTTACTAGGCTTATTGAATCAAGT
TTGGGAAGCATTGCCACAAAGTTTAACTTCTTCATTCACAACCTTGCTCAGCTTCGTTTT
TCTGGTCTTCCTTCTAATGATGAGCCCATCCTTTCATTTTCACCTAAAACATACTCCTTT
AGACAAGATGGTCGAATCAAGGAAGTCTCTGTTTTTACATATCATAAGAAATACAACCCA
GATAAACATTATATTTATGTAGTCCGAATTTTGAGGGAAGGACAGATTGAACCATCATTT
GTCTTCCGAACATTTGACGAATTTCAGGAACTTCACAATAAGCTCAGTATTATTTTTCCA
CTTTGGAAGTTACCAGGCTTTCCTAATAGGATGGTTCTAGGAAGAACACACATAAAAGAT
GTAGCAGCCAAAAGGAAAATTGAGTTAAACAGTTACTTACAGAGTTTGATGAATGCTTCA
ACGGATGTAGCAGAGTGTGATCTTGTTTGTACTTTCTTCCACCCTTTACTTCGTGATGAG
AAAGCTGAAGGGATAGCTAGGTCTGCAGATGCAGGTTCCTTCAGTCCTACTCCAGGCCAA
ATAGGAGGAGCTGTGAAATTATCCATCTCTTACCGAAATGGTACTCTTTTCATCATGGTG
ATGCATATCAAAGATCTTGTTACTGAAGATGGAGCTGACCCAAATCCATATGTCAAAACA
TACCTACTTCCAGATAACCACAAAACATCCAAACGTAAAACCAAAATTTCACGAAAAACG
AGGAATCCGACATTCAATGAAATGCTTGTATACAGTGGATATAGCAAAGAAACCCTAAGA
CAGCGAGAACTTCAACTAAGTGTACTCAGTGCAGAATCTCTGCGGGAGAATTTTTTCTTG
GGTGGAGTAACCCTGCCTTTGAAAGATTTCAACTTGAGCAAAGAGACGGTTAAATGGTAT
CAGCTGACTGCGGCAACATACTTGTAAACTAGTGAATGTCTGAGCTTTGGAAGCATGAAC
AGTTATAAACGTGCATGCATACATGCACACACACACAGAC
Restriction Sites Please inquire     
ACCN NM_002645
Insert Size 5200 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The ORF of this clone is found to be a perfect match to NM_002645.1.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002645.1, NP_002636.1
RefSeq Size 5061 bp
RefSeq ORF 5061 bp
Locus ID 5286
Cytogenetics 11p15.1
Domains C2, PI3K_rbd, PI3_PI4_kinase, PI3Ka, PX, PI3K_C2
Protein Families Druggable Genome
Protein Pathways Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
Gene Summary 'The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]'

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