PCDHA2 (NM_018905) Human Untagged Clone

CAT#: SC309402

PCDHA2 (untagged)-Human protocadherin alpha 2 (PCDHA2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA2
• Synonyms: PCDH-ALPHA2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_018905, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGTCTTCTATCAGAAGGGGCCGAGGGGCCTGGACACGGCTGCTCTCGCTTCTGCTCCTCGCAGCCT
  GGGAGGTGGGGAGCGGCCAGCTCCGCTACTCCGTCCCCGAGGAGGCCAAACACGGCACCTTCGTGGGCCG
  CATCGCGCAGGACCTGGGGCTGGAGCTGGAGGAGCTGGTGCCGCGCCTGTTCCGGGTGGCGTCCAAAAGA
  CACGGGGACCTTCTGGAGGTAAATCTGCAGAATGGCATTTTGTTTGTGAATTCTCGGATCGACCGGGAGG
  AGCTGTGCGGGCGGAGCGCGGAATGTAGCATCCACGTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTT
  CCATGTGGAAGTGGAGGTGAAGGACATTAACGACAACCCGCCAATATTTCCAATGACAGTAAAGACTATC
  CGGTTTCCCGAATCAAGGCTGCTTGATTCTCGGTTTCCTCTAGAGGGAGCATCTGATGCAGATATAGGAG
  TAAATGCTCTTCTCTCCTACAAGCTCAGCTCCAGTGAGTTTTTCTTCCTAGATATACAGGCAAATGATGA
  ACTAAGCGAATCTTTGTCTCTCGTGCTGGGGAAATCGCTGGACAGAGAGGAAACTGCTGAGGTTAATTTG
  TTACTGGTGGCTACTGATGGGGGCAAACCTGAGCTCACGGGCACCGTTCAAATACTTATTAAGGTATTAG
  ATGTAAATGACAATGAACCAACTTTTGCCCAATCAGTTTACAAAGTAAAATTGTTAGAGAATACGGCAAA
  TGGGACCTTAGTGGTTAAGTTAAACGCTTCTGATGCAGATGAAGGACCGAACAGCGAGATTGTGTATTCA
  CTCGGTAGTGATGTGTCCTCCACTATACAGACTAAGTTTACCATAGATCCCATCTCAGGGGAAATCAGAA
  CTAAGGGAAAATTAGATTATGAAGAAGCAAAGTCCTACGAGATTCAGGTCACTGCAACTGACAAAGGAAC
  CCCTTCAATGTCAGGACATTGTAAAATTTCATTAAAACTTGTGGACATCAATGATAACACACCAGAAGTC
  TCAATAACGTCTCTCTCACTTCCCATCTCAGAGAACGCTTCCCTGGGCACTGTCATTGCTCTCATCACGG
  TGTCGGATCGCGACTCTGGTACGAATGGACATGTCACCTGCTCCCTGACGCCCCACGTCCCTTTCAAGCT
  GGTGTCCACCTTCAAGAATTACTACTCGTTGGTGCTGGACAGCGCCCTGGACCGCGAGAGCGTGTCAGCC
  TATGAGCTGGTGGTGACCGCACGGGACGGGGGCTCGCCTTCACTGTGGGCCACCACCAGCGTGTCCATCG
  AGGTGGCCGACGTGAACGACAACGCGCCGGCGTTCGCACAGCCTGAGTACACAGTATTCGTGAAGGAGAA
  CAACCCGCCGGGCTGCCACATCTTCACGGTGTCAGCGTGGGATGCGGACGCGCAGGAGAACGCGCTGGTG
  TCCTACTCGCTGGTGGAGCGGCGGGTGGGCGAGCGCGCGTTGTCGAGCTACGTTTCGGTGCACGCGGAGA
  GCGGCAAGGTGTACGCGCTGCAGCCGCTGGACCACGAGGAAGTGGAGCTGCTGCAGTTCCAGGTGAGCGC
  GCGGGATGCGGGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
  AACGCGCCGGCACTGTTGGCGCCTAGGGCTGGCACCGCTGCTGGCGCAGTGAGTGAGCTGGTGCCGTGGT
  CGGTGGGTGCAGGGCACGTGGTGGCGAAGGTGCGCGCAGTGGACGCTGACTCAGGCTACAACGCGTGGCT
  TTCGTACGAGCTTCAGCTGGGTACTGGCAGCGCTCGCATCCCGTTCCGCGTGGGGCTATACACGGGTGAG
  ATCAGCACGACACGTGCCCTAGACGAGGCTGACTCCCCTCGACACCGCCTACTCGTGCTGGTGAAGGACC
  ACGGCGAACCAGCGTTGACAGCCACGGCCACCGTGTTAGTGTCGTTGGTGGAAAGTGGCCAGGCACCCAA
  GGCCTCGTCGCGGGCGTGGGTGGGCGCCGCGGGCTCAGAGGCTACGCTGGTGGATGTCAACGTGTACCTG
  ATCATCGCCATCTGCGCGGTATCCAGCCTGTTGGTGCTCACGGTGCTGCTGTACACTGCGCTGCGGTGCT
  CGGTGCCACCCACCGAGGGTGCGCGCGCGCCAGGAAAGCCCACGCTGGTGTGCTCCAGCGCCGTGGGGAG
  CTGGTCTTACTCGCAGCAGAGGCGGCAGAGGGTGTGCTCTGGGGAGGACCCCCCCAAGACGGACCTCATG
  GCCTTCAGCCCTAGCTTATCTCAAGGTCCAGACTCCGCAGAAGAGAAACAGCTCTCAGAATCAGAATACG
  TAGGAAAGCCACGACAGCCCAACCCTGACTGGCGTTACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTC
  TGTGCACCTAGAGGAGGCTGGCATTCTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCAACAGTA
  TCCAGTGCAACACCAGAACCAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCGGGTGTCAACAGCAACA
  GCTGGACCTTTAAATACGGACCAGGCAACCCCAAACAATCCGGTCCCGGTGAGTTGCCCGACAAATTCAT
  TATCCCAGGATCTCCTGCAATCATCTCCATCCGGCAGGAGCCTACTAACAGCCAAATTGACAAAAGTGAC
  TTCATAACCTTCGGCAAAAAGGAGGAGACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAGACCCAGG
  AGAAAAAAGAGAAAGGGAACAGCACGACTGACAACAGTGACCAGTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_018905
• ORF Size: 2847 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_018905.2, NP_061728.1
• RefSeq Size: 5360
• RefSeq ORF: 2847
• Locus ID: 56146
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) includes the constant region exons and encodes the longest isoform (1).