Cullin 7 (CUL7) (NM_014780) Human Untagged Clone

CAT#: SC309435

CUL7 (untagged)-Human cullin 7 (CUL7), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CUL7
• Synonyms: 3M1; CUL-7; dJ20C7.5; KIAA0076
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014780, the custom clone sequence may differ by one or more nucleotides
  ATGGTGGGAGAACTCCGCTACAGGGAATTCAGGGTGCCCCTGGGGCCCGGCTTACATGCC
  TATCCTGATGAGCTGATCCGCCAGCGCGTGGGCCATGATGGGCATCCTGAGTACCAGATC
  CGTTGGCTCATCCTGCGGCGTGGCGATGAGGGGGACGGGGGCTCTGGCCAAGTGGACTGC
  AAGGCTGAGCACATCCTGCTGTGGATGTCCAAGGATGAGATCTATGCCAACTGCCACAAG
  ATGCTGGGCGAGGATGGCCAGGTCATCGGGCCCTCCCAGGAGTCTGCAGGGGAGGTTGGG
  GCCCTGGACAAATCTGTGCTGGAGGAGATGGAAACCGACGTGAAGTCCCTCATTCAGAGA
  GCCCTTCGGCAGCTGGAGGAGTGTGTGGGCACTATCCCTCCTGCTCCTCTACTTCACACT
  GTCCACGTGCTCAGCGCCTATGCCAGCATTGAGCCCCTCACTGGAGTATTCAAGGACCCA
  AGGGTCCTGGACTTGCTCATGCACATGTTGAGTAGTCCTGATTATCAGATTCGCTGGAGT
  GCAGGCCGGATGATACAAGCCCTGTCCTCCCATGACGCTGGGACCCGGACTCAGATCCTT
  CTGTCACTGAGCCAACAAGAAGCCATTGAGAAACACCTGGATTTTGACAGCCGCTGTGCT
  CTGCTAGCACTGTTTGCACAGGCCACGCTCTCTGAACACCCCATGTCTTTCGAGGGCATT
  CAGCTACCACAGGTCCCAGGAAGGGTGCTCTTCTCCCTGGTGAAGCGGTATTTGCATGTC
  ACCTCGCTCCTGGATCAGCTGAACGACAGTGCTGCGGAGCCAGGAGCCCAGAACACCTCT
  GCTCCTGAGGAGTTGAGTGGGGAGAGGGGTCAACTGGAGCTGGAGTTCAGTATGGCCATG
  GGCACCCTGATCTCGGAGCTGGTGCAAGCCATGCGCTGGGACCAGGCCTCAGACAGACCA
  AGGAGCTCAGCACGGTCCCCCGGTTCCATCTTCCAGCCTCAGCTGGCAGATGTGAGCCCA
  GGGCTCCCCGCTGCCCAGGCTCAGCCCTCCTTCAGGAGGTCAAGACGTTTTCGCCCTCGT
  TCTGAGTTCGCAAGTGGCAATACCTATGCTTTGTATGTGCGGGACACACTGCAGCCGGGG
  ATGCGAGTGCGGATGCTGGATGATTATGAGGAGATCAGTGCCGGGGATGAGGGCGAGTTT
  CGGCAGAGCAACAACGGTGTGCCTCCTGTGCAGGTATTTTGGGAGTCAACAGGCCGCACC
  TATTGGGTGCACTGGCACATGCTGGAGATCTTGGGCTTTGAGGAAGACATTGAGGACATG
  GTTGAGGCTGATGAGTACCAAGGGGCAGTGGCCAGTAGAGTCCTGGGTAGAGCCCTGCCT
  GCCTGGCGCTGGAGGCCCATGACAGAACTCTATGCTGTGCCTTATGTGCTGCCTGAGGAT
  GAGGACACTGAGGAGTGTGAACACCTGACCCTGGCTGAGTGGTGGGAACTCCTCTTCTTC
  ATCAAGAAGCTGGATGGACCTGACCATCAGGAGGTTCTCCAGATCCTCCAGGAGAACCTA
  GATGGGGAGATTCTGGATGATGAGATCCTAGCTGAACTGGCCGTGCCCATAGAATTGGCC
  CAGGACTTGCTGCTGACTCTGCCACAGCGACTCAATGACAGTGCCCTCAGGGACCTGATC
  AACTGCCATGTCTACAAGAAGTATGGGCCTGAAGCCCTAGCAGGGAACCAAGCCTACCCA
  TCCCTTCTAGAAGCCCAAGAAGATGTCCTCCTGCTAGACGCGCAGGCCCAGGCTAAGGAC
  TCAGAAGATGCAGCCAAAGTGGAAGCAAAAGAACCCCCATCTCAGAGTCCCAACACTCCC
  CTGCAGCGTCTGGTGGAGGGTTATGGTCCAGCTGGGAAAATCCTCCTGGATCTAGAGCAA
  GCCCTCAGCTCAGAGGGGACCCAGGAGAACAAGGTCAAGCCACTCCTGCTGCAGCTGCAG
  CGGCAGCCGCAGCCCTTCCTGGCACTGATGCAGAGCCTGGACACTCCGGAGACTAACAGG
  ACCCTGCACCTGACTGTGCTGAGAATCCTGAAGCAGCTGGTGGACTTCCCCGAGGCACTG
  CTGCTCCCCTGGCACGAGGCCGTGGATGCCTGCATGGCCTGCCTGCGGTCCCCAAACACT
  GATCGAGAGGTGCTCCAGGAACTGATTTTCTTCCTGCACCGCCTGACCTCAGTGAGCAGG
  GACTATGCCGTGGTGCTGAATCAGCTGGGAGCAAGAGACGCTATCTCCAAGGCCCTGGAA
  AAGCACCTGGGAAAGCTGGAGCTGGCTCAGGAGCTGCGGGACATGGTGTTCAAGTGTGAG
  AAGCATGCCCACCTCTACCGCAAACTCATCACCAACATCCTGGGAGGCTGCATCCAGATG
  GTGCTGGGCCAGATCGAAGACCACAGACGAACCCACCAACCCATCAACATCCCTTTCTTT
  GATGTGTTCCTCAGATACCTGTGCCAGGGCTCCAGTGTGGAAGTGAAGGAGGACAAGTGC
  TGGGAGAAGGTGGAGGTGTCCTCCAACCCGCACCGGGCCAGCAAGCTGACGGACCACAAC
  CCCAAGACCTATTGGGAGTCCAACGGCAGCGCCGGCTCCCACTACATCACCCTGCACATG
  CGCCGGGGCATCCTCATCAGGCAACTGACTCTGCTTGTGGCTAGTGAGGACTCGAGTTAC
  ATGCCGGCCCGAGTGGTGGTGTGCGGGGGTGATAGCACTAGCTCTCTTCACACGGAACTC
  AACTCGGTGAATGTGATGCCCTCTGCCAGCCGGGTGATCCTCCTGGAGAACCTGACCCGC
  TTCTGGCCCATCATCCAGATCCGCATAAAGCGCTGCCAGCAGGGTGGCATTGATACGCGC
  ATTCGGGGGTTAGAGATCCTAGGCCCCAAGCCCACGTTCTGGCCAGTGTTCCGGGAGCAG
  CTCTGTCGTCACACACGCCTCTTCTACATGGTTCGGGCACAGGCCTGGAGCCAGGACATG
  GCAGAGGACCGCAGGAGCCTCCTGCACCTGAGTTCTAGACTCAACGGTGCTCTGCGCCAG
  GAGCAGAATTTTGCTGACCGCTTCCTCCCTGATGACGAGGCTGCCCAAGCTCTGGGCAAG
  ACCTGCTGGGAGGCCCTGGTCAGCCCCGTGGTGCAGAACATCACCTCCCCTGATGAGGAT
  GGCATTAGCCCCCTGGGTTGGCTGCTGGACCAGTACCTGGAGTGTCAGGAAGCTGTCTTC
  AACCCCCAGAGCCGCGGCCCAGCTTTCTTCTCGCGGGTGCGCCGTCTCACTCACCTGCTG
  GTGCATGTCGAGCCCTGTGAGGCACCCCCTCCTGTGGTGGCCACTCCTCGGCCCAAAGGC
  AGAAACAGAAGCCACGACTGGAGCTCCTTGGCTACCCGGGGCCTTCCAAGCAGCATCATG
  AGAAACCTGACGCGCTGTTGGCGGGCCGTGGTGGAGAAGCAGGTGAACAATTTTCTGACC
  TCATCCTGGCGGGATGATGACTTTGTGCCACGCTACTGTGAGCACTTTAATATTCTGCAG
  AACTCAAGCTCTGAACTGTTTGGGCCTCGGGCAGCCTTCTTGCTGGCGCTGCAAAATGGC
  TGTGCGGGAGCCTTGCTGAAGCTCCCTTTTCTCAAAGCTGCCCACGTGAGTGAGCAGTTC
  GCCCGGCACATTGACCAGCAGATCCAGGGCAGCCGGATCGGTGGAGCCCAGGAAATGGAG
  AGGCTGGCACAGCTGCAGCAATGCCTGCAAGCTGTCCTGATTTTCTCCGGCTTGGAGATA
  GCCACCACTTTTGAGCATTATTACCAGCACTACATGGCGGACCGTCTCCTGGGCGTGGTC
  TCGAGCTGGCTGGAGGGGGCCGTGCTGGAGCAGATCGGTCCCTGCTTCCCCAACCGCCTC
  CCCCAGCAGATGTTGCAGAGCCTGAGCACCTCTAAGGAGCTGCAGCGCCAGTTCCACGTC
  TACCAGCTCCAGCAGCTGGATCAGGAACTCCTGAAGCTGGAGGATACAGAGAAGAAAATA
  CAGGTGGGCCTTGGGGCCAGTGGCAAGGAGCACAAGAGCGAGAAGGAAGAGGAAGCTGGG
  GCAGCAGCAGTGGTGGATGTGGCGGAGGGAGAGGAGGAAGAGGAGGAGAATGAGGACCTC
  TACTATGAAGGGGCAATGCCAGAAGTGTCTGTGCTTGTCCTGTCCCGACACTCCTGGCCT
  GTTGCCTCAATCTGCCACACACTGAACCCCAGAACCTGCCTGCCCTCCTACCTGAGGGGC
  ACTTTGAACAGATACTCCAACTTCTACAACAAGAGTCAGAGCCACCCTGCCCTTGAGCGA
  GGCTCACAGAGGCGACTGCAGTGGACGTGGCTGGGCTGGGCTGAGCTGCAGTTTGGGAAC
  CAGACCCTGCATGTGTCCACCGTGCAGATGTGGCTACTGCTGTATCTCAACGACCTGAAG
  GCGGTCTCTGTGGAGAGTCTGCTGGCGTTCTCAGGGCTCTCCGCAGACATGCTCAATCAG
  GCGATTGGGCCCCTCACCTCTTCAAGAGGCCCCCTGGACCTTCACGAGCAAAAGGATATA
  CCAGGAGGGGTCCTCAAGATTCGAGATGGCAGCAAGGAACCCAGGTCGAGATGGGACATT
  GTGCGGCTCATCCCACCTCAGACGTACCTGCAAGCTGAGGGTGAAGACGGCCAGAACTTG
  GAGAAGAGACGGAATCTTCTGAACTGCCTCATCGTCCGAATCCTCAAGGCCCATGGAGAT
  GAGGGGCTGCACATTGACCAGCTTGTCTGTCTGGTGCTGGAGGCTTGGCAGAAGGGCCCG
  TGTCCTCCCAGGGGTTTGGTCAGCAGCCTTGGTAAGGGGTCTGCATGCAGCAGCACTGAC
  GTCCTCTCCTGCATCCTACACCTCCTGGGCAAGGGCACGCTGAGACGCCATGACGACCGG
  CCCCAGGTGCTGTCCTATGCAGTCCCTGTGACTGTCATGGAGCCTCACACTGAGTCCCTG
  AACCCAGGCTCCTCAGGCCCCAACCCACCCCTCACCTTCCATACCCTACAGATTCGCTCC
  CGGGGTGTGCCCTATGCCTCCTGCACTGCCACCCAGAGCTTCTCTACCTTCCGGTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_014780
• ORF Size: 5097 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014780.3, NP_055595.2
• RefSeq Size: 5491
• RefSeq ORF: 5097
• Locus ID: 9820
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
  Transcript Variant: This variant (2) uses alternate splice junctions at the 3' end of two different exons compared to variant 1. One alternate splice junction causes a frameshift compared to variant 1 while the other does not. The resulting isoform (2) has a longer N-terminus and contains an alternate segment compared to isoform 1.