PER2 (NM_022817) Human Untagged Clone

CAT#: SC309597

PER2 (untagged)-Human period homolog 2 (Drosophila) (PER2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PER2
• Synonyms: FASPS; FASPS1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_022817, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAATGGATACGCGGAATTTCCGCCCAGCCCCAGTAACCCCACCAAGGAGCCCGTGGAGCCCCAGCCCA
  GCCAGGTCCCACTGCAGGAAGATGTGGACATGAGCAGTGGCTCCAGTGGACATGAGACCAACGAAAACTG
  CTCCACGGGGCGGGACTCGCAGGGCAGTGACTGTGACGACAGTGGGAAGGAGCTGGGGATGCTGGTGGAG
  CCACCGGATGCCCGCCAGAGTCCAGATACCTTTAGCCTGATGATGGCAAAATCTGAACACAACCCATCTA
  CAAGTGGCTGCAGTAGCGACCAGTCTTCGAAAGTGGACACACACAAAGAACTGATAAAAACACTAAAGGA
  GCTGAAGGTCCACCTCCCTGCAGACAAGAAGGCCAAGGGCAAGGCCAGTACGCTGGCCACCTTGAAGTAC
  GCCCTCAGGAGCGTGAAGCAGGTGAAAGCCAATGAAGAGTATTACCAGCTGCTGATGTCCAGCGAGGGTC
  ACCCCTGTGGAGCAGACGTGCCCTCCTACACCGTGGAGGAGATGGAGAGCGTTACCTCTGAGCACATTGT
  GAAGAATGCCGATATGTTTGCGGTGGCCGTGTCCCTGGTGTCTGGGAAGATCCTGTACATCTCTGACCAG
  GTTGCATCCATATTTCACTGTAAAAGAGATGCCTTCAGCGATGCCAAGTTTGTGGAGTTCCTGGCGCCTC
  ACGATGTGGGCGTGTTCCACAGTTTCACCTCCCCGTACAAGCTTCCCTTGTGGAGCATGTGCAGTGGAGC
  AGATTCTTTTACTCAAGAATGCATGGAGGAGAAATCTTTCTTTTGCCGTGTCAGTGTCCGGAAAAGCCAC
  GAGAATGAAATCCGCTACCACCCCTTCCGCATGACGCCCTACCTGGTCAAGGTGCGGGACCAACAAGGTG
  CTGAGAGTCAGCTTTGCTGCCTTCTGCTGGCAGAGAGAGTGCACTCTGGTTATGAAGCCCCTAGAATTCC
  TCCTGAAAAGAGAATTTTTACAACCACCCATACACCAAATTGTTTGTTCCAGGATGTGGATGAAAGGGCG
  GTCCCTCTCCTGGGCTACCTACCTCAGGACCTGATTGAAACCCCAGTGCTCGTGCAGCTCCACCCTAGTG
  ACAGGCCCTTGATGCTGGCCATCCACAAAAAGATCCTGCAGTCAGGCGGGCAGCCTTTCGACTATTCTCC
  CATTCGGTTTCGCGCCCGGAACGGAGAGTACATCACGTTGGACACCAGCTGGTCCAGCTTCATCAACCCA
  TGGAGCAGGAAAATCTCCTTCATCATTGGGAGGCACAAAGTCAGGGTGGGCCCTTTGAATGAGGACGTGT
  TTGCAGCCCACCCCTGCACAGAGGAGAAGGCCCTGCACCCCAGCATTCAGGAGCTCACAGAGCAGATCCA
  CCGGCTCCTGCTGCAGCCCGTCCCCCACAGCGGCTCCAGTGGCTACGGGAGTCTGGGCAGCAACGGGTCC
  CACGAGCACCTTATGAGCCAGACCTCCTCCAGCGACAGCAACGGCCATGAGGACTCACGCCGGAGGAGAG
  CCGAAATTTGTAAAAATGGTAACAAGACCAAAAATAGAAGTCATTATTCTCATGAATCTGGAGAACAAAA
  GAAAAAATCCGTTACAGAAATGCAAACTAATCCCCCAGCTGAGAAGAAAGCTGTCCCTGCCATGGAAAAG
  GACAGCCTGGGGGTCAGCTTCCCCGAGGAGTTGGCCTGCAAGAACCAGCCCACCTGCTCCTACCAGCAGA
  TCAGCTGCTTGGACAGCGTCATCAGGTACTTGGAGAGCTGCAATGAGGCTGCCACCCTGAAGAGGAAATG
  CGAGTTCCCAGCAAACGTCCCAGCGCTAAGGTCCAGTGATAAGCGGAAGGCCACAGTCAGCCCAGGGCCA
  CACGCTGGAGAGGCAGAGCCGCCCTCCAGGGTGAACAGCCGCACGGGAGTAGGTACGCACCTGACCTCGC
  TGGCACTGCCGGGCAAGGCAGAGAGTGTGGCGTCGCTCACCAGCCAGTGCAGCTACAGCAGCACCATCGT
  CCATGTGGGAGACAAGAAGCCGCAGCCGGAGTTAGAGATGGTGGAAGATGCTGCGAGTGGGCCAGAATCC
  CTGGACTGCCTGGCGGGCCCTGCCCTGGCCTGTGGTCTCAGCCAAGAGAAGGAGCCCTTCAAGAAGCTGG
  GCCTCACCAAGGAGGTACTCGCTGCACACACACAGAAGGAGGAGCAGAGCTTCCTGCAGAAGTTCAAAGA
  AATAAGAAAACTCAGCATTTTCCAGTCCCACTGCCATTACTACTTGCAAGAAAGATCCAAGGGGCAGCCA
  AGTGAACGAACTGCCCCTGGACTAAGAAATACTTCCGGAATAGATTCACCTTGGAAAAAAACAGGAAAGA
  ACAGAAAATTGAAGTCCAAGCGGGTCAAACCTCGAGACTCATCTGAGAGCACCGGATCTGGGGGGCCCGT
  GTCCGCCCGGCCCCCGCTGGTGGGCTTGAACGCCACAGCCTGGTCACCCTCAGACACGTCCCAGTCCAGC
  TGCCCAGCCGTGCCCTTTCCCGCCCCAGTGCCAGCAGCTTATTCACTGCCCGTGTTTCCAGCGCCAGGGA
  CTGTGGCAGCACCCCCGGCACCTCCCCACGCCAGCTTCACAGTGCCTGCTGTGCCCGTGGACCTCCAGCA
  CCAGTTTGCAGTCCAGCCCCCACCTTTCCCTGCCCCTTTGGCGCCTGTCATGGCATTCATGCTACCCAGT
  TATTCCTTCCCCTCGGGGACCCCAAACCTGCCCCAGGCCTTCTTCCCCAGCCAGCCTCAGTTTCCGAGCC
  ACCCCACACTCACATCCGAGATGGCCTCTGCCTCACAGCCTGAGTTCCCCAGCCGGACCTCGATCCCCAG
  ACAGCCATGTGCTTGTCCAGCCACCCGGGCCACCCCACCATCGGCCATGGGTAGGGCCTCCCCACCGCTC
  TTTCAGTCCCGCAGCAGCTCGCCCCTGCAGCTCAACCTGCTGCAGCTGGAGGAAGCCCCTGAGGGTGGCA
  CTGGAGCCATGGGGACCACAGGGGCCACAGAGACAGCAGCTGTAGGGGCGGACTGCAAACCTGGCACTTC
  TCGGGACCAGCAGCCGAAGGCGCCTCTGACCCGTGATGAACCCTCAGACACACAGAACAGTGACGCCCTT
  TCCACGTCAAGCGGCCTCCTAAACCTCCTGCTGAATGAGGACCTCTGCTCAGCCTCGGGCTCTGCTGCTT
  CGGAGTCTCTGGGCTCCGGCTCACTGGGCTGCGACGCCTCCCCGAGTGGGGCAGGCAGTAGTGACACAAG
  TCATACCAGCAAATATTTTGGAAGCATTGACTCCTCAGAGAATAATCACAAAGCAAAAATGAACACTGGT
  ATGGAAGAAAGTGAGCATTTCATTAAGTGCGTCCTGCAGGATCCCATCTGGCTGCTGATGGCAGATGCGG
  ACAGCAGCGTCATGATGACGTACCAGCTGCCTTCCCGAAATTTAGAAGCGGTTTTGAAGGAGGACAGAGA
  GAAGCTGAAGCTCCTACAGAAACTCCAGCCCAGGTTCACGGAGAGTCAGAAGCAGGAGCTGCGCGAGGTC
  CACCAGTGGATGCAGACGGGCGGCCTGCCCGCAGCCATCGACGTGGCAGAATGTGTTTACTGTGAAAACA
  AGGAAAAAGGTAATATTTGCATACCATATGAGGAAGATATTCCTTCTCTGGGACTCAGCGAAGTGTCGGA
  CACCAAAGAAGACGAAAATGGATCCCCCTTGAATCACAGGATCGAAGAGCAGACGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_022817
• ORF Size: 3768 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_022817.2, NP_073728.1
• RefSeq Size: 6342
• RefSeq ORF: 3768
• Locus ID: 8864
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Circadian rhythm - mammal
• Gene Summary: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]