PCDHGA8 (NM_032088) Human Untagged Clone

CAT#: SC309600

PCDHGA8 (untagged)-Human protocadherin gamma subfamily A, 8 (PCDHGA8), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHGA8
• Synonyms: PCDH-GAMMA-A8
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_032088, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCGCTCCACAGAGTCGCCCCAGACGCGGCGAGCTGATCCTGCTGTGCGCGCTGCTGGGAACGCTGT
  GGGAAATCGGGAGGGGACAGATTCGCTACTCTGTGCCAGAAGAGACGGACAAAGGCTCCTTCGTGGGTAA
  TATCTCCAAGGACCTGGGGCTGGACCCCCGGAAGCTGGCGAAGCACGGAGTCCGTATCGTCTCCAGAGGT
  AGGACGCAGCTCTTTGCTCTGAACCCGCGCAGCGGCAGCTTGATCACCGCGGGCAGGATAGATCGGGAGG
  AGCTCTGCGCTCAGAGCCCGCGGTGTCTGATAAATATTAACACCCTGGTTGAGGATAAAGGAAAACTCTT
  TGGGGTAGAAATAGAAATAATTGATATTAACGATAATAACCCAAAATTCCAGGTCGAAGATCTAGAAGTA
  AAAATTAACGAAATCGCGGTTCCTGGAGCACGTTATCCACTCCCAGAAGCTGTTGACCCGGATGTGGGCG
  TGAACTCCCTCCAGAGCTACCAGCTCAGCCCCAATCACCACTTCTCCCTGGACGTGCAGACTGGAGACAA
  TGGAGCCATAAACCCAGAGCTGGTGCTGGAGCGCGCCCTGGACAGGGAGGAAGAGGCTGCTCACCACCTG
  GTCCTCACGGCCTCGGATGGCGGCAAGCCGCCTCGCTCTAGCACAGTGCGCATCCACGTGACAGTGTTGG
  ATACAAATGACAATGCCCCGGTTTTTCCTCACCCGATTTACCGAGTGAAAGTCCTTGAGAACATGCCCCC
  AGGCACGCGGCTGCTTACTGTAACAGCCAGCGACCCGGATGAGGGAATCAACGGAAAAGTGGCATACAAA
  TTCCGGAAAATTAATGAAAAACAAACTCCGTTATTCCAGCTTAATGAAAATACTGGGGAAATATCAATAG
  CAAAAAGTCTAGATTATGAAGAATGTTCATTTTATGAAATGGAAATACAAGCCGAAGATGTGGGGGCACT
  TCTGGGGAGGACCAAATTGCTCATTTCGGTGGAAGATGTAAATGACAATAGACCAGAAGTGATCATTACG
  TCTTTGTTTAGCCCAGTGTTAGAAAATTCTCTTCCCGGGACAGTAATTGCCTTCTTGAGTGTGCATGACC
  AAGACTCTGGAAAGAATGGTCAAGTTGTCTGTTACACACGTGATAATTTACCTTTTAAATTAGAAAAGTC
  AATAGGTAATTATTATAGATTAGTGACAAGGAAATATTTGGACCGAGAAAATGTCTCTATCTACAATATC
  ACAGTGATGGCCTCAGATCTAGGAACACCACCTCTGTCCACTGAAACTCAAATCGCTCTGCACGTGGCAG
  ACATTAACGACAACCCTCCTACTTTCCCTCATGCCTCCTACTCAGCGTATATCCTAGAGAACAACCTGAG
  AGGAGCCTCCATCTTTTCCTTGACTGCACACGACCCCGACAGCCAGGAGAATGCCCAGGTCACTTACTCT
  GTGACCGAGGACACGCTGCAGGGGGCGCCCCTGTCCTCGTATATCTCCATCAACTCTGACACCGGTGTCC
  TGTATGCGCTGCAATCTTTCGACTATGAGCAGATCCGAGACCTGCAGCTACTGGTAACAGCCAGCGACAG
  CGGGGACCCGCCCCTCAGCAGCAACATGTCACTGAGCCTGTTCGTGCTGGACCAGAATGACAACGCGCCC
  GAGATCCTGTACCCCGCCCTCCCCACAGACGGTTCCACTGGCGTGGAGCTGGCGCCCCGCTCCGCAGAGC
  GTGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACAGAGACTCGGGCCAGAACGCCTGGCTGTCCTACCG
  CCTGCTCAAGGCCAGCGAGCCGGGACTCTTCTCGGTGGGTCTGCACACGGGCGAGGTGCGCACGGCGCGA
  GCCCTGCTGGACAGAGATGCGCTCAAGCAGAGCCTCGTGGTGGCCGTCCAGGACCATGGCCAGCCCCCTC
  TCTCCGCCACTGTCACGCTCACCGTAGCCGTGGCTGACAGCATCCCCGAAGTCCTGACCGAGTTGGGCAG
  TCTGAAGCCTTCGGTCGACCCGAACGATTCGAGCCTTACACTCTATCTCGTGGTGGCAGTGGCTGCCATC
  TCCTGTGTCTTCCTCGCCTTTGTCGCTGTGCTTCTGGGGCTCAGGCTGAGGCGCTGGCACAAGTCACGCC
  TGCTCCAGGATTCCGGTGGCAGATTGGTAGGCGTGCCTGCCTCACATTTTGTGGGTGTTGAGGAGGTACA
  GGCTTTCCTGCAGACCTATTCCCAGGAAGTCTCCCTCACCGCCGACTCGCGGAAGAGTCACCTGATCTTT
  CCCCAGCCCAACTACGCAGACATGCTCATCAGTCAGGAGGGCTGTGAGAAAAATGATTCTTTGTTAACAT
  CCGTAGATTTTCATGAATATAAGAATGAAGCTGATCATGGTCAGCAAGCCCCGCCCAACACGGACTGGCG
  TTTCTCTCAGGCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAAC
  AACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCTGATGGGAGCT
  CCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGACCCCAGTTCACCCTGCAGCA
  CGTGCCCGACTACCGCCAGAATGTCTACATCCCAGGCAGCAATGCCACACTGACCAACGCAGCTGGCAAG
  CGGGATGGCAAGGCCCCAGCAGGTGGCAATGGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_032088
• ORF Size: 2799 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_032088.1, NP_114477.1
• RefSeq Size: 5503
• RefSeq ORF: 2799
• Locus ID: 9708
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) includes the constant region exons and encodes the longest isoform (1).