Phospholipase C beta 1 (PLCB1) (NM_015192) Human Untagged Clone

CAT#: SC309945

PLCB1 (untagged)-Human phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PLCB1
• Synonyms: EIEE12; PI-PLC; PLC-154; PLC-beta-1; PLC-I; PLC154; PLCB1A; PLCB1B
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015192 edited
  GCAGAATCCGCCGCGACTGGCAGCCTCGGCTGACCGGCTCGGCTTCTCTTCGCCTTCCGA
  GGCTCCTCATCCACCGCGGGCTCCAGACCTCGCGTCCCGCCCGGGGCATGGCCGGGCGCT
  GCGCCCCCGCGCGCTCTGCCTGCTGAGCGGCGCCGGAGGGAGGTGCGGAGGCCGGGAGGC
  CGGGGAGGCCGGCTGGGAGCAGAGTCGAGCGCCTCCGGAGCAGAGAAAGGAGCCCGCGCC
  CCGCGCCCCGCGCCCCGCGCACGGTCCCCAGTCCCTGCCGCGCTCGCCCGGGCCGCCCGG
  AGCCCAGATGAGCCCAGATGGCCGGGGCTCAACCCGGAGTGCACGCCTTGCAACTCAAGC
  CCGTGTGCGTGTCCGACAGCCTCAAGAAGGGCACCAAATTCGTCAAGTGGGATGATGATT
  CAACTATTGTTACTCCAATTATTTTGAGGACTGACCCTCAGGGATTTTTCTTTTACTGGA
  CAGATCAAAACAAGGAGACAGAGCTACTGGATCTCAGCCTTGTCAAAGATGCCAGATGTG
  GGAGACACGCCAAAGCTCCCAAGGACCCCAAATTACGTGAACTTTTGGATGTGGGGAACA
  TCGGGCGCCTGGAGCAGCGCATGATCACAGTGGTGTATGGGCCTGACCTCGTGAACATCT
  CCCATTTGAATCTCGTGGCTTTCCAAGAAGAAGTGGCCAAGGAATGGACAAATGAGGTTT
  TCAGTTTGGCAACAAACCTGCTGGCCCAAAACATGTCCAGGGATGCATTTCTGGAAAAAG
  CCTATACTAAACTTAAGCTGCAAGTCACTCCAGAAGGGCGTATTCCTCTCAAAAACATAT
  ATCGCTTGTTTTCAGCAGATCGGAAGCGAGTTGAAACTGCTTTAGAGGCTTGTAGTCTTC
  CATCTTCAAGGAATGATTCAATACCTCAAGAAGATTTCACTCCAGAAGTGTACAGAGTTT
  TCCTCAACAACCTTTGCCCTCGACCTGAAATTGATAACATCTTTTCAGAATTTGGTGCAA
  AAAGCAAACCATATCTTACCGTTGATCAGATGATGGATTTTATCAACCTTAAGCAGCGAG
  ATCCTCGGCTTAATGAAATACTTTATCCACCTCTAAAACAAGAGCAAGTCCAAGTATTGA
  TTGAGAAGTATGAACCCAACAACAGCCTCGCCAGAAAAGGACAAATATCAGTGGATGGGT
  TCATGCGCTATCTGAGTGGAGAAGAAAACGGAGTCGTTTCACCTGAGAAACTGGATTTGA
  ATGAAGACATGTCTCAGCCCCTTTCTCACTATTTCATTAATTCCTCGCACAACACCTACC
  TCACAGCTGGCCAACTGGCTGGAAACTCCTCTGTTGAGATGTATCGCCAAGTGCTCCTGT
  CTGGTTGTCGCTGTGTGGAGCTGGACTGCTGGAAGGGACGGACTGCAGAAGAGGAACCTG
  TCATCACCCATGGCTTCACCATGACAACTGAAATATCTTTCAAGGAAGTGATAGAAGCAA
  TTGCGGAGTGTGCATTTAAGACTTCACCTTTTCCAATTCTCCTTTCGTTTGAGAACCATG
  TGGATTCCCCAAAGCAGCAAGCCAAGATGGCGGAGTACTGCCGACTGATCTTTGGGGATG
  CCCTTCTCATGGAGCCCCTGGAAAAATATCCACTGGAATCTGGAGTTCCTCTTCCAAGCC
  CTATGGATTTAATGTATAAAATTTTGGTGAAAAATAAGAAGAAATCACACAAGTCATCAG
  AAGGAAGCGGCAAAAAGAAGCTCTCAGAACAAGCCTCCAACACCTACAGTGACTCCTCCA
  GCATGTTCGAGCCCTCATCCCCAGGAGCCGGAGAAGCTGATACGGAAAGTGACGACGACG
  ATGATGATGATGACTGTAAAAAATCTTCAATGGATGAGGGGACTGCTGGAAGTGAGGCTA
  TGGCCACAGAAGAAATGTCTAATCTGGTGAACTATATTCAGCCAGTCAAGTTTGAGTCAT
  TTGAAATTTCAAAAAAAAGAAATAAAAGTTTTGAAATGTCTTCCTTCGTGGAAACCAAAG
  GACTTGAACAACTCACCAAGTCTCCAGTGGAATTTGTAGAATATAACAAAATGCAGCTTA
  GCAGGATATATCCAAAAGGAACACGTGTGGATTCATCCAACTATATGCCTCAGCTCTTCT
  GGAATGCAGGTTGTCAGATGGTGGCACTTAATTTCCAGACAATGGACCTGGCTATGCAAA
  TAAATATGGGGATGTATGAATACAACGGGAAGAGTGGCTACAGATTGAAGCCAGAGTTCA
  TGAGGAGGCCTGACAAGCATTTTGATCCATTTACTGAAGGCATCGTAGATGGGATAGTGG
  CAAACACTTTGTCTGTTAAGATTATTTCAGGTCAGTTTCTTTCTGATAAGAAAGTTGGGA
  CTTACGTGGAAGTAGATATGTTTGGTTTGCCTGTGGATACAAGGAGGAAGGCATTTAAGA
  CCAAAACATCCCAAGGAAATGCTGTGAATCCTGTCTGGGAAGAAGAACCTATTGTGTTCA
  AAAAGGTGGTTCTTCCTACTCTGGCCTGTTTGAGAATAGCAGTTTATGAAGAAGGAGGTA
  AATTCATTGGCCACCGTATCTTGCCAGTGCAAGCCATTCGGCCAGGCTATCACTATATCT
  GTCTAAGGAATGAAAGGAACCAGCCTCTGACGCTGCCTGCTGTCTTTGTCTACATAGAAG
  TGAAAGACTATGTGCCAGACACATATGCAGATGTCATCGAAGCTTTATCAAACCCAATCC
  GATATGTGAACCTGATGGAACAGAGAGCTAAGCAATTGGCTGCTTTGACACTGGAAGATG
  AAGAAGAAGTAAAGAAAGAGGCTGATCCTGGAGAAACACCATCAGAGGCTCCAAGTGAAG
  CGAGAACGACTCCAGCAGAAAATGGGGTGAATCACACTACAACCCTGACACCCAAGCCAC
  CCTCCCAGGCTCTCCACAGCCAGCCAGCTCCAGGTTCTGTAAAGGCACCTGCCAAAACAG
  AAGATCTTATTCAGAGTGTCTTAACAGAAGTGGAAGCACAGACCATCGAAGAACTAAAGC
  AACAGAAATCGTTTGTGAAACTTCAAAAGAAACACTACAAAGAAATGAAAGACCTGGTTA
  AGAGACACCACAAGAAAACCACTGACCTTATCAAAGAACACACTACCAAGTATAATGAAA
  TTCAGAATGACTACTTGAGAAGGAGAGCCGCTTTGGAAAAGTCCGCCAAAAAGGACAGTA
  AGAAAAAATCGGAACCCAGCAGCCCTGATCATGGTTCATCAACGATTGAGCAAGACCTCG
  CTGCCCTGGATGCTGAAATGACCCAAAAGTTAATAGACTTGAAGGACAAACAACAGCAGC
  AGCTGCTTAATCTTCGGCAAGAACAGTATTATAGTGAAAAATACCAGAAGCGAGAACATA
  TTAAACTGCTTATTCAAAAGTTGACGGATGTCGCAGAAGAGTGTCAGAACAATCAGTTAA
  AGAAGCTCAAAGAAATCTGTGAGAAAGAAAAGAAAGAATTAAAGAAGAAAATGGATAAAA
  AGAGGCAGGAGAAGATAACAGAAGCTAAATCCAAAGACAAAAGTCAGATGGAAGAGGAGA
  AGACAGAGATGATCCGGTTATATATCCAGGAAGTGGTGCAGTATATCAAGAGGCTAGAAG
  AAGCGCAAAGTAAACGGCAAGAAAAACTCGTAGAGAAACACAAGGAAATACGTCAGCAGA
  TCCTGGATGAAAAGCCCAAGCTGCAGGTGGAGCTGGAGCAAGAATACCAAGACAAATTCA
  AAAGACTGCCCCTCGAGATTTTGGAATTCGTGCAGGAAGCCATGAAAGGAAAGATCAGTG
  AAGACAGCAATCACGGTTCTGCCCCTCTCTCCCTGTCCTCAGACCCTGGAAAAGTGAACC
  ACAAGACTCCCTCCAGTGAGGAGCTGGGAGGAGACATCCCAGGAAAAGAATTTGATACTC
  CTCTGTGAATGCTCCTGCCAGGCCTTCAGAAATTGCATGGCCACTCCAGCGTCATCGGAC
  TCTCTCTTATTACAAAGATCACTGCCCAGGACCATCTTCCCGAGAAGCATCCCTTAGCCT
  AAAATCCACACCAAAGGGAGAGTTCCAGAGGAATCCATGAAGAATTCCCATGCCCAGGCT
  CCATGTGTCATGTGGAAACCTCCACAGGTCTGCTAGTGAAGAATGCATGTATGTGAGATT
  TTTGTTTTCTTTCCAATAGCAAATTCAAAGCAAGCAACTTGCAGGCTCCATGGAACTTTT
  AATGAAGGACAGTGTCTTCTTTGAAGAAAATCAAGCTCGTGTTTTTATTCGAAGCTCTGG
  TGTAAAATATTTCAAAGTCATAGAAATAGTTTGAGAAATGCATAGCATTATTTAACACTA
  TTGAACAGCCGACTTTGAGCATTGTTTCTTCTAACTGCCCCTCAACTACCATTATCTTCA
  AGTCAACATGCATATTACATTTTCATCCTTTGCTTTGCAAGCACTGGTGGCTTGCAGTTT
  GCTAATTTATTTATCATAGAGTCATCAATGTATTTGTTGCTGACATGGTTTTATTAGATA
  CTGTAGTGATTCAAATAAGTTTTCTATTTGAAAAAAAAAATCACTTGATTGTATCCTTGC
  CCAGTGAAGCCATCCTAAGACTTAGCAATATGGATTGTACATTTGGCTGCATGAGCAAGT
  CGGCCGCACACTTCCAGACAGTGTGCTGTTTGAATTGACTATTTGCACTCAAAGTCTGGG
  TATTCATTGGTTATTGGCCTGAAATGATCAAATAACTACAAATGATCTGTTGAATAAAAA
  TAGTTGAGCTGATATATGTTAAGCAGATATTCAATCAGAATGAACAGGTTCCGGTGGTTA
  TTTTGCCGTTTGACATTTTTTATGGTTCATTTATTTTTAATATAGAGAGGAAGATTGAAT
  ATTTATCTAGAGAATACAAAGACCCACATGTAAATGATAGGTATTATCTCCATGTATATA
  TGTACCCACTTAGTCATGTAAGTGCATATACACATACACACACATGAGTGTAGACATGTG
  TTTATTAATTGACAATGACCCAAATCTCTTCCACAAGACTTAAAACCAAATTCAGGGACA
  AATGGATAGAGAAGAAAAGGGTCAAACATCGAGATTACATGGATGTTAAATTATATGGAG
  ACGCTAAGAAATAATTGATGGAGCCATTGATGCAAACCGAAGTAGATTTAGAACTTATAT
  GAATTTGATTTATATTTTGCAAGATCAAAAATTAGATGTTAAGTATCAGATTTTAAGCTT
  GTTTTAATGGTCAAAAAATTAGGACAGAAATAATATGGACATTTATTAGTATCTTCCATA
  ATTTTTAAGTCTGACACATTTCTATTTTATTCTAACATAAAAAAACTTCCATTATATATT
  TACTAAGTATATTTAATTCACTTAACTCTGTCTTTATAAGTTCCTATTTTAGATGGAATA
  AGAGAAACAAATTATATCAAGGTAAAACTGATCAAAAGCATAATTGAAAGTTCTGAAAAA
  AGAAAAATAATAATATGTAGAAAAATGTAACTTAGAGAGTAACACATGAACATTGAAGTT
  AAAACCCAGAAGCCAGATGCTCACAGTTTTATTTTACTTTAAAATAAACCTGTCTGACTG
  TAGCTTTGTGAAATATCTTAAAACGCAAAAACCAATTGTGTCCTGAAAATTGTTTCAAGA
  ATTTAATATTTTTATGAAAATTATTTTATTTAACTTTAAGCAATAACTAGAGATTACAAT
  TAAATTTTAATCAAAATGAAGGCTTAGTTCAAACATAAGGAAACAGTGTTTGATTAAAAA
  AAACACATCTAGTAAGACGTAAGGGGAAAATCACATCCTCTTTGGAGATGATTATATTTT
  GATCTGAAGGGTTTGGGGTGTTCATTAGACACTTAATAAAACTTAACTTCCAATGAAAAA
  GAAATCTTTTGTAAATCATTCTACTTTTGCACTTTGAAAGAAAGGCGTTAATCATAAAGA
  AGCAAGAATGGTCAAAATCGAATGCTGCATTTTTATAAACAAAATTACAGACTGTCTGAA
  ATTGAAGAAGAATGAACTAATAATAGCATTCATAACCAAACACAATGATGATTATTGCAG
  AACATTGTATCACATTTTAGTCCAGAGATAGAATAAAGTTGAATAACCTTGACTTACACA
  AAACTGTTTTGGTAGTTGGATTTCATTATCTTAGTGAATTTAGTCATTTTACAATATGTT
  TGTATTTGGCCATTTACTGTAATCACATTTTTATATCTGTACAATGACACTTTTTGCAGT
  TGTGGGGTAGTGTGTAACACTGTCCATCTTGCATCATTGAAACTACTACAATGATACTAT
  CATTTAATAATATTAATATTACTTGAAATAGACTAAGATAAAGAAAAGGGGTCTGTATGA
  TGTGCAGTTTTGTGCCTTTATGTATTTGCCTTGTTCTTTGTCGAATGTGTGAAATTCTGT
  ACTGTGGTTTTTCCTATAATAGAAAGTAGAGCTGTGTATTAAATTAGACTGTGTCTCTCT
  GATACCTTTACACTACTGAGAATAGCATGGTTTTGGCCATGTAAACCAATTTTCAAAGTT
  CTAATGACATAGCCATGTGTTTTTGGTTTTTTATATTTCATTTTAAAATTTGAGTATCAC
  CATACATTAATTAATACTCCTGTAGTAGATAAGCTGTCATTAAGTAATTCCCAAAAAGGG
  CCATTTGCTTGCATTACTTTGAATTTAATGTTGCGCTTGTGCACTGTGTTAATATTGTTT
  GTGATGGATTGGACGTTGTGACTCTTGCCTTTTAAGAAGAAAAAAAAGATAGGACAAAGT
  ATTTGAAGCTCTTAAAATGTACATATTTTGGTTCTTCTATCTCAAATTATTTAAAATGCA
  TAATTCACATTTTTGTAATAATTCTATGCAATTTTGTGGCATGATGTTTCTTCCACTTGT
  AATTTTATGTGCTTTCATCACAAATCCAAAGGAAAGAATAAAAATTTCTTAACACAAAAA
  AAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_015192
• ORF Size: 3651 bp
• Insert Size: 7100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid.

Reference Data

• RefSeq: NM_015192.2, NP_056007.1
• RefSeq Size: 6705
• RefSeq ORF: 3651
• Locus ID: 23236
• Domains: C2, PI-PLC-X, PI-PLC-Y
• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway, Chemokine signaling pathway, Gap junction, GnRH signaling pathway, Huntington's disease, Inositol phosphate metabolism, Long-term depression, Long-term potentiation, Melanogenesis, Metabolic pathways, Phosphatidylinositol signaling system, Vascular smooth muscle contraction, Wnt signaling pathway
• Gene Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (a).