ALDH8A1 (NM_170771) Human Untagged Clone

CAT#: SC310397

ALDH8A1 (untagged)-Human aldehyde dehydrogenase 8 family, member A1 (ALDH8A1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ALDH8A1
• Synonyms: ALDH12; DJ352A20.2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_170771, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTGGAACAAACGCACTTTTGATGCTGGAAAACTTCATAGATGGAAAATTTTTACCTTGTAGCTCAT
  ATATAGATTCTTACGACCCATCAACAGGGGAAGTGTATTGCAGAGTGCCAAATAGTGGAAAAGACGAGAT
  CGAAGCCGCGGTCAAGGCCGCCAGAGAAGCCTTTCCCAGCTGGTCATCCCGCAGCCCCCAGGAGCGCTCA
  CGGGTCCTGAACCAGGTGGCGGATTTGCTGGAGCAGTCCCTGGAGGAGTTTGCCCAGGCCGAGTCTAAAG
  ACCAAGGGAAAACCTTAGCACTGGCAAGAACCATGGACATTCCCCGGTCTGTGCAGAACTTCAGGTTCTT
  CGCTTCCTCCAGCCTGCACCACACGTCAGAGTGCACGCAGATGGACCACCTGGGCTGCATGCACTACACG
  GTGCGGGCCCCGGTGGGAGTCGCTGGTCTGATCAGCCCCTGGAATTTGCCACTCTACTTGCTGACCTGGA
  AGATAGCTCCAGCGATGGCTGCAGGGAACACTGTGATAGCCAAGCCCAGTGAGCTGACTTCAGTGACTGC
  GTGGATGTTGTGCAAACTCCTGGATAAAGCAGGTGTTCCACCAGGTGTGGTCAATATTGTGTTTGGAACC
  GGGCCCAGGGTGGGTGAGGCCCTGGTGTCCCACCCAGAGGTGCCCCTGATCTCCTTCACCGGGAGCCAGC
  CCACCGCTGAGCGGATCACCCAGCTGAGCGCTCCCCACTGCAAAAAGCTCTCCCTGGAGCTGGGGGGCAA
  GAATCCTGCCATCATCTTTGAGGACGCCAACCTGGATGAGTGCATTCCGGCAACCGTCAGGTCCAGCTTT
  GCCAACCAGGTCAGAAGTTACGTCAAGAGAGCTCTTGCTGAAGGTGCCCAAATTTGGTGCGGTGAGGGAG
  TGGATAAGTTGAGCCTCCCTGCCAGGAACCAGGCAGGCTACTTTATGCTTCCCACGGTGATAACAGACAT
  TAAGGATGAATCCTGCTGCATGACGGAAGAGATATTTGGTCCAGTGACGTGTGTCGTCCCCTTTGATAGT
  GAAGAGGAGGTGATTGAAAGAGCCAACAACGTTAAGTATGGGCTGGCGGCTACCGTGTGGTCCAGCAATG
  TGGGGCGCGTCCACCGGGTGGCTAAGAAGCTGCAGTCTGGCTTGGTCTGGACCAACTGCTGGCTCATCAG
  GGAGCTGAACCTTCCTTTCGGGGGGATGAAGAGTTCTGGAATAGGTAGAGAGGGAGCCAAGGACTCTTAC
  GACTTCTTCACTGAGATCAAAACCATCACCGTTAAACACTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_170771
• ORF Size: 1302 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_170771.2, NP_739577.1
• RefSeq Size: 2405
• RefSeq ORF: 1302
• Locus ID: 64577
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the aldehyde dehydrogenase family of proteins. The encoded protein has been implicated in the synthesis of 9-cis-retinoic acid and in the breakdown of the amino acid tryptophan. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. In addition, this enzyme has been shown to catalyze the conversion of 2-aminomuconic semialdehyde to 2-aminomuconate in the kynurenine pathway of tryptophan catabolism. [provided by RefSeq, Jul 2018]
  Transcript Variant: This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter protein (isoform 2), that is missing an internal segment compared to isoform 1.