RGR (NM_002921) Human Untagged Clone

CAT#: SC310563

RGR (untagged)-Human retinal G protein coupled receptor (RGR), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RGR
• Synonyms: RP44
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002921 edited
  GGGAGAGTGAGGATGGCAGAGACCAGTGCCTTGCCCACCGGCTTCGGGGAGCTCGAGGTG
  CTGGCTGTGGGGATGGTGCTACTGGTGGAAGCTCTCTCCGGTCTCAGCCTCAATACCCTG
  ACCATCTTCTCTTTCTGCAAGACCCCGGAGCTGCGGACTCCCTGCCACCTACTGGTGCTG
  AGCTTGGCTCTTGCGGACAGTGGGATCAGCCTGAATGCCCTCGTTGCAGCCACATCCAGC
  CTTCTCCGTGTCTCCCACAGGCGCTGGCCCTACGGCTCGGACGGCTGCCAGGCTCACGGC
  TTCCAGGGCTTTGTGACAGCGTTGGCCAGCATCTGCAGCAGTGCAGCCATCGCATGGGGG
  CGTTATCACCACTACTGCACCCGTAGCCAGCTGGCCTGGAACTCAGCCGTCTCTCTGGTG
  CTCTTCGTGTGGCTGTCTTCTGCCTTCTGGGCAGCTCTGCCCCTTCTGGGTTGGGGTCAC
  TATGACTATGAGCCACTGGGGACATGCTGCACCCTGGACTACTCCAAGGGGGACAGAAAC
  TTCACCAGCTTCCTCTTCACCATGTCCTTCTTCAACTTCGCCATGCCCCTCTTCATCACG
  ATCACTTCCTACAGTCTCATGGAGCAGAAACTGGGGAAGAGTGGCCATCTCCAGGTAAAC
  ACCACTCTGCCAGCAAGGACGCTGCTGCTCGGCTGGGGCCCCTATGCCATCCTGTATCTA
  TACGCAGTCATCGCAGACGTGACTTCCATCTCCCCCAAACTGCAGATGGTGCCCGCCCTC
  ATTGCCAAAATGGTGCCCACGATCAATGCCATCAACTATGCCCTGGGCAATGAGATGGTC
  TGCAGGGGAATCTGGCAGTGCCTCTCACCGCAGAAGAGGGAGAAGGACCGAACCAAGTGA
  GCCTGCCACCCTGGAGTGAGCCCCAGGCCAGGAGGCTGTTCCAGGAGTCCTGCCCAGCAG
  CCTCGGTGGCCAAGCCCAGACACTCACCCACCTTCCCCAGTGGCCCCGTGGATCCTGGTC
  CTAGGCTGGACACAGGATTCAGAAAGACACCAGGCTGCACAGAAAGAGCCAGATGGACCT
  GAGTGTCGGTCACAGCCCCCTACACTCAAGGCTGAGAGGCCTCAGGAAAGTCATTCCTTT
  TTAAAAATAATAATAAATGTAAGGGGGTACAGTGCAGTTTTGTTACATGGATAGATTGCC
  TAGTGGTGAAGTCTGGGCTTTTAGTGTAACCATCACCCTAATAATATACGTTGTACCCAT
  TAAGTTATTTCTCATCCCTCACCCCCTCCCACCTTGTCACCCTTCTGAGTCTCCAATGTC
  TATTATTCCACACTCCATGTCCACGTGTACACATTATTTAGCTCCCACTTACAAGTGAGA
  ACATGTGGTATTTGACTTTCTGTTTTTGAGTTATTTCACTTAAAATAATGACCTCCAGTT
  TCATCCATGTTGCTGCAAAAGACATGATCTCGTTCTTTTTTATGGCAGTGTAGTATTCCA
  TTCCATATACATATATAAACGTTATATATATGTAACGTTTTCTTTATCCAATCATCTGTT
  GATGGATAGATTCCATATCTTTGCTACTGTAAACAGAGCTGTGATAAGCATACAAGTGCA
  GGTTTCTTTTTGATATACTGATTTCTTTTCCTTTGGGTAGATACCAGTAGTAGGACTGCT
  GGATCAAATGGTAGCTCTATTTTTAAGACAGTATGGAGAAATCACCATACTGTTTTCCAT
  AGGGGTTGTACTAATTTACAGTCCCACCAACAGTGTATAGGTGTTCCCTTTTCTCTGCAT
  CCTTACCAATATCTGTAATTTTTTGACTTTTTAATAATAGCCATTCTCATTTGTGTGAGA
  TAAGGTCTCATTGTGGTTTTAATTTCCATTTCTCTGATGACTTTTGATGTTAAGCATTTT
  TTCATATGCTTCTTAGCCACGTGTATGTATTCTTTTTGAAAAAATGTTTATTCATGTCTT
  TTGCCCACTTTTTAATGGCATTATTTGGATTTTTTTTGTTGAGTTATTTGAGTTTCTTAT
  ATATTCTGGATAATAGTCTGGATAATATATTCTGGATAATATATAATAGTCTTATATATT
  CTGGATATATTCTGGATACATGGTTTGCAAATATTTTCTCCGGTTCTGCACGTTGTTCAT
  TCTGTTGATGGTTTATTTTGCTGTGCAGAAACTTTTTTAGTTTAATTAAGTCCCATTTGT
  CTAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_002921
• Insert Size: 2300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: It is not a varient.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002921.3, NP_002912.2
• RefSeq Size: 1475 bp
• RefSeq ORF: 888 bp
• Locus ID: 5995
• Cytogenetics: 10q23.1
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: 'This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).