JIP3 (MAPK8IP3) (NM_001040439) Human Untagged Clone

CAT#: SC310710

MAPK8IP3 (untagged)-Human mitogen-activated protein kinase 8 interacting protein 3 (MAPK8IP3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAPK8IP3
• Synonyms: JIP-3; JIP3; JSAP1; NEDBA; syd; SYD2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001040439, the custom clone sequence may differ by one or more nucleotides
  ATGATGGAGATCCAGATGGACGAGGGCGGCGGCGTGGTGGTGTACCAGGACGACTACTGC
  TCCGGCTCGGTGATGTCGGAGCGGGTGTCGGGCCTGGCGGGCTCCATCTACCGCGAGTTC
  GAGCGCCTCATCCACTGCTACGACGAGGAGGTGGTCAAGGAGCTCATGCCGCTGGTGGTG
  AACGTGCTGGAGAACCTAGACTCGGTGCTCAGCGAGAACCAGGAGCACGAGGTGGAGCTG
  GAGCTGCTGCGCGAGGACAACGAGCAGCTGCTCACCCAGTACGAGCGTGAGAAGGCGCTG
  CGCAGGCAGGCGGAGGAGAAATTCATTGAGTTTGAAGATGCTCTGGAACAAGAGAAGAAA
  GAGCTGCAAATCCAGGTGGAGCACTACGAGTTCCAGACGCGCCAGCTGGAGCTGAAGGCC
  AAGAACTATGCCGATCAGATTTCCCGGTTGGAGGAGCGGGAGTCGGAGATGAAGAAGGAG
  TACAATGCCCTGCACCAGCGGCACACAGAGATGATACAGACCTACGTGGAGCACATTGAG
  AGGTCCAAGATGCAGCAGGTCGGAGGAAACAGCCAGACCGAGAGCAGCCTGCCGGGGCGG
  AGGAAGGAGCGCCCCACCTCCCTGAACGTGTTCCCCCTGGCTGACGGCACGGTACGTGCA
  CAGATCGGGGGCAAGCTCGTGCCTGCGGGGGACCACTGGCACCTGAGTGACCTCGGCCAG
  CTGCAGTCCAGCTCCAGCTACCAGTGTCCACAGGATGAAATGTCCGAGTCAGGCCAGTCC
  TCGGCGGCCGCCACACCCAGCACCACAGGCACCAAGTCCAACACGCCCACATCCTCCGTG
  CCCTCGGCCGCCGTCACACCCCTCAACGAGAGCCTGCAGCCCCTGGGGGACTATGGCGTG
  GGCTCCAAGAACAGCAAGCGTGCCCGGGAGAAGCGCGACAGCCGCAACATGGAAGTACAG
  GTCACCCAGGAGATGCGCAACGTCAGTATAGGCATGGGCAGCAGTGACGAGTGGTCTGAT
  GTTCAAGACATTATTGACTCCACGCCAGAGCTGGACATGTGTCCAGAGACCCGCCTGGAC
  CGCACAGGAAGCAGCCCAACCCAGGGCATCGTGAACAAAGCTTTCGGCATCAACACCGAC
  TCCCTGTACCATGAGCTGTCGACGGCAGGGTCTGAGGTCATCGGGGATGTGGACGAAGGG
  GCCGACCTCCTAGGGGAGTTCTCAGGAATGGGCAAAGAAGTGGGGAATCTGCTACTGGAA
  AACTCACAGCTTCTGGAAACCAAAAACGCCTTGAATGTGGTGAAGAATGACCTGATTGCC
  AAGGTCGACCAGCTGTCCGGGGAGCAGGAGGTGCTGAGGGGCGAGTTGGAGGCTGCTAAG
  CAGGCCAAAGTCAAGCTGGAAAACCGTATCAAGGAGCTGGAAGAGGAACTGAAAAGAGTG
  AAGTCCGAGGCCATCATCGCCCGCCGTGAACCCAAAGAAGAGGCGGAGGATGTAAGCAGC
  TATCTCTGTACAGAATCGGACAAAATCCCCATGGCCCAGCGCCGCCGCTTCACGCGGGTG
  GAGATGGCCCGTGTGCTCATGGAGCGGAACCAGTACAAGGAGCGGCTGATGGAGCTGCAG
  GAGGCTGTGCGGTGGACTGAGATGATCAGAGCGTCCCGAGAGCACCCATCCGTCCAGGAG
  AAGAAGAAGTCGACCATCTGGCAGTTCTTCAGCCGCCTCTTCAGCTCTTCCTCCAGCCCC
  CCTCCGGCCAAGCGCCCCTATCCCTCGGTGAACATCCACTACAAGTCACCCACCACTGCC
  GGCTTCAGCCAGCGCCGCAACCATGCCATGTGCCCGATCTCGGCAGGCAGCCGGCCCCTG
  GAATTCTTCCCTGACGACGACTGCACGTCCTCCGCCCGTCGAGAGCAGAAGCGCGAGCAG
  TACCGCCAGGTGCGTGAGCACGTGCGTAACGACGACGGCCGTCTGCAGGCCTGCGGCTGG
  AGCCTGCCCGCCAAGTACAAGCAGCTGAGTCCCAACGGGGGCCAGGAGGACACGCGGATG
  AAGAACGTGCCGGTGCCGGTGTACTGCCGCCCTCTGGTGGAGAAGGACCCCACCATGAAG
  CTGTGGTGTGCCGCGGGCGTCAACCTGAGCGGGTGGAGGCCCAATGAGGACGACGCTGGG
  AATGGAGTCAAGCCAGCGCCAGGCCGCGATCCCCTGACCTGCGACCGCGAAGGAGACGGC
  GAGCCCAAGAGCGCCCACACGTCTCCCGAGAAGAAGAAGGCCAAGGAGCTCCCTGAAATG
  GACGCCACCTCCAGCCGGGTGTGGATCCTGACCAGCACCCTGACCACCAGCAAGGTGGTG
  ATCATCGACGCCAACCAGCCGGGCACGGTGGTGGACCAGTTCACCGTCTGCAACGCGCAC
  GTGCTGTGCATCTCCAGCATCCCCGCGGCCAGCGACAGCGACTACCCTCCCGGGGAGATG
  TTCCTGGACAGCGACGTGAACCCAGAGGACCCGGGCGCAGATGGCGTGCTGGCCGGTATC
  ACCCTGGTGGGCTGTGCCACCCGCTGCAACGTGCCGCGGAGCAACTGCTCCTCCCGAGGG
  GACACCCCAGTGCTAGACAAGGGGCAGGGGGAGGTGGCCACCATCGCCAACGGGAAGGTC
  AACCCGTCCCAGTCCACAGAGGAGGCCACAGAGGCCACGGAGGTGCCAGACCCTGGGCCC
  AGCGAGCCAGAGACAGCCACATTGCGGCCCGGGCCTCTCACAGAGCACGTCTTCACTGAC
  CCAGCCCCGACCCCGTCCTCTGGCCCCCAGCCTGGCAGCGAGAACGGGCCAGAGCCTGAC
  AGCAGCAGCACACGGCCAGAGCCAGAGCCCAGCGGGGACCCCACGGGAGCAGGCAGCAGT
  GCTGCACCCACCATGTGGCTGGGAGCCCAGAACGGCTGGCTCTATGTGCACTCGGCTGTG
  GCCAACTGGAAGAAGTGCCTGCACTCCATCAAGCTGAAGGATTCTGTGCTGAGCCTGGTG
  CATGTCAAAGGCCGTGTGCTGGTGGCTCTGGCGGACGGGACCCTGGCCATCTTCCACCGT
  GGTGAAGATGGCCAGTGGGATCTGAGCAACTATCACCTAATGGACCTGGGCCACCCGCAC
  CACTCCATCCGCTGCATGGCTGTTGTGTACGACCGCGTGTGGTGTGGCTACAAGAACAAG
  GTGCACGTCATCCAGCCCAAGACCATGCAGATAGAGAAGTCATTTGACGCCCACCCGCGG
  CGGGAGAGCCAGGTGCGGCAGCTGGCGTGGATCGGCGATGGCGTATGGGTGTCCATCCGC
  CTGGACTCCACCCTGAGGCTCTACCATGCACACACGCACCAGCATCTACAGGACGTGGAC
  ATTGAGCCCTACGTCAGCAAGATGCTAGGCACTGGCAAGCTGGGTTTCTCCTTCGTACGC
  ATCACGGCCCTGCTTGTCGCGGGCAGCCGGCTCTGGGTGGGCACCGGCAACGGAGTGGTC
  ATCTCCATCCCCCTGACAGAGACTGTGGTCCTGCACCGAGGCCAGCTCCTGGGGCTCCGA
  GCCAATAAGACATCCCCCACCTCTGGGGAGGGCGCCCGTCCCGGGGGCATCATCCACGTG
  TATGGCGATGACAGCAGTGACAGGGCGGCCAGCAGCTTCATCCCCTACTGCTCCATGGCC
  CAGGCCCAGCTATGCTTCCATGGGCACCGCGATGCCGTGAAGTTCTTTGTCTCGGTGCCA
  GGGAACGTGCTGGCCACCCTGAATGGGAGTGTGCTGGACAGCCCAGCCGAGGGCCCTGGG
  CCAGCTGCCCCTGCCTCGGAGGTCGAGGGCCAGAAGCTGCGGAACGTGCTGGTGCTGAGC
  GGCGGGGAGGGCTACATCGACTTCCGCATTGGAGACGGAGAGGACGACGAGACGGAGGAG
  GGCGCAGGGGACATGAGCCAGGTGAAGCCCGTGCTGTCCAAGGCAGAGCGCAGTCACATC
  ATCGTGTGGCAGGTGTCCTACACCCCCGAGTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001040439
• ORF Size: 3993 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001040439.1, NP_001035529.1
• RefSeq Size: 5635
• RefSeq ORF: 3993
• Locus ID: 23162
• Protein Families: Druggable Genome
• Protein Pathways: MAPK signaling pathway
• Gene Summary: The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.